Tumor-targeted micelle-forming block copolymers for overcoming of multidrug resistance
Braunová, Alena, Kostka, Libor, Sivák, Ladislav, Cuchalová, Lucie, Hvězdová, Zuzana, Laga, Richard, Filippov, Sergey, Černoch, Peter, Pechar, Michal, Janoušková, Olga, Šírová, Milada, Etrych, Tomáš
Published in Journal of controlled release (10.01.2017)
Published in Journal of controlled release (10.01.2017)
Get full text
Journal Article
Neutrophils in Cancer immunotherapy: friends or foes?
Huang, Xueqin, Nepovimova, Eugenie, Adam, Vojtech, Sivak, Ladislav, Heger, Zbynek, Valko, Marian, Wu, Qinghua, Kuca, Kamil
Published in Molecular cancer (18.05.2024)
Published in Molecular cancer (18.05.2024)
Get full text
Journal Article
IL-2/JES6-1 mAb complexes dramatically increase sensitivity to LPS through IFN-γ production by CD25 + Foxp3 - T cells
Tomala, Jakub, Weberova, Petra, Tomalova, Barbora, Jiraskova Zakostelska, Zuzana, Sivak, Ladislav, Kovarova, Jirina, Kovar, Marek
Published in eLife (21.12.2021)
Published in eLife (21.12.2021)
Get full text
Journal Article
Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK)
Huang, Xueqin, You, Li, Nepovimova, Eugenie, Psotka, Miroslav, Malinak, David, Valko, Marian, Sivak, Ladislav, Korabecny, Jan, Heger, Zbynek, Adam, Vojtech, Wu, Qinghua, Kuca, Kamil
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2023)
Get full text
Journal Article
Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling
Sivák, Ladislav, Šubr, Vladimír, Kovářová, Jiřina, Dvořáková, Barbora, Šírová, Milada, Říhová, Blanka, Randárová, Eva, Kraus, Michal, Tomala, Jakub, Studenovský, Martin, Vondráčková, Michaela, Sedláček, Radislav, Makovický, Petr, Fučíková, Jitka, Vošáhlíková, Šárka, Špíšek, Radek, Kostka, Libor, Etrych, Tomáš, Kovář, Marek
Published in Journal of controlled release (10.04.2021)
Published in Journal of controlled release (10.04.2021)
Get full text
Journal Article
BODIPY-labelled acetylcholinesterase reactivators can be encapsulated into ferritin nanovehicles for enhanced bioavailability in the CNS
Prchalova, Eliska, Sukupova, Martina, Malinak, David, Andrys, Rudolf, Sivak, Ladislav, Pekarik, Vladimir, Skarka, Adam, Svobodova, Jana, Prchal, Lukas, Fresser, Lukas, Heger, Zbynek, Musilek, Kamil
Published in Biomedicine & pharmacotherapy (01.11.2023)
Published in Biomedicine & pharmacotherapy (01.11.2023)
Get full text
Journal Article
HPMA Copolymer Mebendazole Conjugate Allows Systemic Administration and Possesses Antitumour Activity In Vivo
Studenovský, Martin, Rumlerová, Anna, Kovářová, Jiřina, Dvořáková, Barbora, Sivák, Ladislav, Kostka, Libor, Berdár, Daniel, Etrych, Tomáš, Kovář, Marek
Published in Pharmaceutics (04.06.2022)
Published in Pharmaceutics (04.06.2022)
Get full text
Journal Article
Overcoming multidrug resistance in Dox-resistant neuroblastoma cell lines via treatment with HPMA copolymer conjugates containing anthracyclines and P-gp inhibitors
Koziolová, Eva, Janoušková, Olga, Cuchalová, Lucie, Hvězdová, Zuzana, Hraběta, Jan, Eckschlager, Tomáš, Sivák, Ladislav, Ulbrich, Karel, Etrych, Tomáš, Šubr, Vladimír
Published in Journal of controlled release (10.07.2016)
Published in Journal of controlled release (10.07.2016)
Get full text
Journal Article
Platinum-based drug-induced depletion of amino acids in the kidneys and liver
Mitrevska, Katerina, Cernei, Natalia, Michalkova, Hana, Rodrigo, Migue Angel Merlos, Sivak, Ladislav, Heger, Zbynek, Zitka, Ondrej, Kopel, Pavel, Adam, Vojtech, Milosavljevic, Vedran
Published in Frontiers in oncology (21.09.2022)
Published in Frontiers in oncology (21.09.2022)
Get full text
Journal Article
Metallothionein-3 is a multifunctional driver that modulates the development of sorafenib-resistant phenotype in hepatocellular carcinoma cells
Rodrigo, Miguel Angel Merlos, Michalkova, Hana, Jimenez, Ana Maria Jimenez, Petrlak, Frantisek, Do, Tomas, Sivak, Ladislav, Haddad, Yazan, Kubickova, Petra, de Los Rios, Vivian, Casal, J Ignacio, Serrano-Macia, Marina, Delgado, Teresa C, Boix, Loreto, Bruix, Jordi, Martinez Chantar, Maria L, Adam, Vojtech, Heger, Zbynek
Published in Biomarker research (09.04.2024)
Published in Biomarker research (09.04.2024)
Get full text
Journal Article
Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P‑gp- and STAT3-Mediated Chemoresistance
Kostka, Libor, Sivák, Ladislav, Šubr, Vladimír, Kovářová, Jiřina, Šírová, Milada, Říhová, Blanka, Sedlacek, Radislav, Etrych, Tomáš, Kovář, Marek
Published in Biomacromolecules (13.06.2022)
Published in Biomacromolecules (13.06.2022)
Get full text
Journal Article
Overcoming multidrug resistance via simultaneous delivery of cytostatic drug and P-glycoprotein inhibitor to cancer cells by HPMA copolymer conjugate
Sivak, Ladislav, Subr, Vladimir, Tomala, Jakub, Rihova, Blanka, Strohalm, Jiri, Etrych, Tomas, Kovar, Marek
Published in Biomaterials (01.01.2017)
Published in Biomaterials (01.01.2017)
Get full text
Journal Article
Proteinase-activated Receptor 2: Springboard of Tumors
Vetvicka, David, Suhaj, Petr, Olejar, Tomas, Sivak, Ladislav, Benes, Jiri, Pouckova, Pavla
Published in Anticancer research (01.01.2024)
Published in Anticancer research (01.01.2024)
Get full text
Journal Article
Engineered human H-chain ferritin with reversed charge of the internal cavity exhibits RNA-mediated spongelike effect for loading RNA/DNA-binding molecules
Charousova, Marketa, Kudlickova Peskova, Marie, Takacsova, Paulina, Kapolkova, Katerina, Haddad, Yazan, Bilek, Jan, Sivak, Ladislav, Bartejs, Tomas, Heger, Zbynek, Pekarik, Vladimir
Published in Biomaterials science (27.02.2024)
Published in Biomaterials science (27.02.2024)
Get full text
Journal Article
Toward understanding the kinetics of disassembly of ferritins of varying origin and subunit composition
Krausova, Katerina, Charousova, Marketa, Kratochvil, Zdenek, Takacsova, Paulina, Tesarova, Barbora, Sivak, Ladislav, Peskova, Marie Kudlickova, Sukupova, Martina, Zivotska, Hana, Makovicky, Pavol, Yamashita, Ichiro, Okamoto, Naofumi, Hynek, David, Haddad, Yazan, Pekarik, Vladimir, Rex, Simona, Heger, Zbynek
Published in Applied materials today (01.08.2022)
Published in Applied materials today (01.08.2022)
Get full text
Journal Article
Polymer inhibitors of ABC transporter overcoming multidrug resistance: synthesis, characterization and in vivo evaluation
Šubr, Vladimír, Koziolová, Eva, Sivák, Ladislav, Říhová, Blanka, Kovář, Marek, Etrych, Tomáš
Published in Journal of controlled release (10.08.2017)
Published in Journal of controlled release (10.08.2017)
Get full text
Journal Article
Polymer inhibitors of ABC transporter overcoming multidrug resistance: Synthesis, characterization and in vitro evaluation
Šubr, Vladimír, Koziolová, Eva, Sivák, Ladislav, Říhová, Blanka, Kovář, Marek, Ulbrich, Karel
Published in Journal of controlled release (10.09.2015)
Published in Journal of controlled release (10.09.2015)
Get full text
Journal Article