The Opioid Crisis and the Future of Addiction and Pain Therapeutics
Coussens, Nathan P, Sittampalam, G Sitta, Jonson, Samantha G, Hall, Matthew D, Gorby, Heather E, Tamiz, Amir P, McManus, Owen B, Felder, Christian C, Rasmussen, Kurt
Published in The Journal of pharmacology and experimental therapeutics (01.11.2019)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2019)
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Journal Article
Metastatic Tumor-in-a-Dish, a Novel Multicellular Organoid to Study Lung Colonization and Predict Therapeutic Response
Ramamoorthy, Prabhu, Thomas, Sufi Mary, Kaushik, Gaurav, Subramaniam, Dharmalingam, Chastain, Katherine M, Dhar, Animesh, Tawfik, Ossama, Kasi, Anup, Sun, Weijing, Ramalingam, Satish, Gunewardena, Sumedha, Umar, Shahid, Mammen, Joshua M, Padhye, Subhash B, Weir, Scott J, Jensen, Roy A, Sittampalam, G Sitta, Anant, Shrikant
Published in Cancer research (Chicago, Ill.) (01.04.2019)
Published in Cancer research (Chicago, Ill.) (01.04.2019)
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Journal Article
Overcoming Wnt–β-catenin dependent anticancer therapy resistance in leukaemia stem cells
Perry, John M., Tao, Fang, Roy, Anuradha, Lin, Tara, He, Xi C., Chen, Shiyuan, Lu, Xiuling, Nemechek, Jacqelyn, Ruan, Linhao, Yu, Xiazhen, Dukes, Debra, Moran, Andrea, Pace, Jennifer, Schroeder, Kealan, Zhao, Meng, Venkatraman, Aparna, Qian, Pengxu, Li, Zhenrui, Hembree, Mark, Paulson, Ariel, He, Zhiquan, Xu, Dong, Tran, Thanh-Huyen, Deshmukh, Prashant, Nguyen, Chi Thanh, Kasi, Rajeswari M., Ryan, Robin, Broward, Melinda, Ding, Sheng, Guest, Erin, August, Keith, Gamis, Alan S., Godwin, Andrew, Sittampalam, G. Sitta, Weir, Scott J., Li, Linheng
Published in Nature cell biology (01.06.2020)
Published in Nature cell biology (01.06.2020)
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Journal Article
Impact of high-throughput screening in biomedical research
Macarron, Ricardo, Banks, Martyn N, Bojanic, Dejan, Burns, David J, Cirovic, Dragan A, Garyantes, Tina, Green, Darren V. S, Hertzberg, Robert P, Janzen, William P, Paslay, Jeff W, Schopfer, Ulrich, Sittampalam, G. Sitta
Published in Nature reviews. Drug discovery (01.03.2011)
Published in Nature reviews. Drug discovery (01.03.2011)
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Journal Article
Book Review
The NCATS Assay Guidance Manual programme: advancing the practice and rigour of preclinical translation
Markossian, Sarine, Brimacombe, Kyle R., Sittampalam, G. Sitta, Grossman, Abigail, Coussens, Nathan P., Inglese, James, Auld, Douglas S., Chin, William, Austin, Christopher P., Hall, Matthew D.
Published in Nature reviews. Drug discovery (01.12.2022)
Published in Nature reviews. Drug discovery (01.12.2022)
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Journal Article
An approach to rapid distributed manufacturing of broad spectrum anti-viral griffithsin using cell-free systems to mitigate pandemics
Borhani, Shayan G., Levine, Max Z., Krumpe, Lauren H., Wilson, Jennifer, Henrich, Curtis J., O’Keefe, Barry R., Lo, Donald C., Sittampalam, G. Sitta, Godfrey, Alexander G., Lunsford, R. Dwayne, Mangalampalli, Venkata, Tao, Dingyin, LeClair, Christopher A., Thole, Aaron P., Frey, Douglas, Swartz, James, Rao, Govind
Published in New biotechnology (25.09.2023)
Published in New biotechnology (25.09.2023)
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Journal Article
Assay Guidance Manual for Drug Discovery: Technologies That Matter
Markossian, Sarine, Coussens, Nathan P., Dahlin, Jayme L., Sitta Sittampalam, G.
Published in SLAS technology (01.12.2021)
Published in SLAS technology (01.12.2021)
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Journal Article
Novel Phenotypic Outcomes Identified for a Public Collection of Approved Drugs from a Publicly Accessible Panel of Assays
Lee, Jonathan A, Shinn, Paul, Jaken, Susan, Oliver, Sarah, Willard, Francis S, Heidler, Steven, Peery, Robert B, Oler, Jennifer, Chu, Shaoyou, Southall, Noel, Dexheimer, Thomas S, Smallwood, Jeffrey, Huang, Ruili, Guha, Rajarshi, Jadhav, Ajit, Cox, Karen, Austin, Christopher P, Simeonov, Anton, Sittampalam, G Sitta, Husain, Saba, Franklin, Natalie, Wild, David J, Yang, Jeremy J, Sutherland, Jeffrey J, Thomas, Craig J
Published in PloS one (15.07.2015)
Published in PloS one (15.07.2015)
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Journal Article
The translational science training program at NIH: Introducing early career researchers to the science and operation of translation of basic research to medical interventions
Gilliland, C. Taylor, Sittampalam, G. Sitta, Wang, Philip Y., Ryan, Philip E.
Published in Biochemistry and molecular biology education (01.01.2017)
Published in Biochemistry and molecular biology education (01.01.2017)
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Journal Article
Effects of respiratory mechanical forces on the pharmacological response of lung cancer cells to chemotherapeutic agents
Hendricks, Peter, Diaz, Francisco J., Schmitt, Sarah, Sitta Sittampalam, G., Nirmalanandhan, Victor Sanjit
Published in Fundamental & clinical pharmacology (01.10.2012)
Published in Fundamental & clinical pharmacology (01.10.2012)
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Journal Article
The third international meeting on genetic disorders in the RAS/MAPK pathway: Towards a therapeutic approach
Korf, Bruce, Ahmadian, Reza, Allanson, Judith, Aoki, Yoko, Bakker, Annette, Wright, Emma Burkitt, Denger, Brian, Elgersma, Ype, Gelb, Bruce D., Gripp, Karen W., Kerr, Bronwyn, Kontaridis, Maria, Lazaro, Conxi, Linardic, Corinne, Lozano, Reymundo, MacRae, Calum A., Messiaen, Ludwine, Mulero-Navarro, Sonia, Neel, Benjamin, Plotkin, Scott, Rauen, Katherine A., Roberts, Amy, Silva, Alcino J., Sittampalam, Sitta G., Zhang, Chao, Schoyer, Lisa
Published in American journal of medical genetics. Part A (01.08.2015)
Published in American journal of medical genetics. Part A (01.08.2015)
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Journal Article
Conference Proceeding
Fully Three-Dimensional Bioprinted Skin Equivalent Constructs with Validated Morphology and Barrier Function
Derr, Kristy, Zou, Jinyun, Luo, Keren, Song, Min Jae, Sittampalam, G. Sitta, Zhou, Chao, Michael, Sam, Ferrer, Marc, Derr, Paige
Published in Tissue engineering. Part C, Methods (01.06.2019)
Published in Tissue engineering. Part C, Methods (01.06.2019)
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Journal Article
Small-Molecule Screens: A Gateway to Cancer Therapeutic Agents with Case Studies of Food and Drug Administration-Approved Drugs
Coussens, Nathan P, Braisted, John C, Peryea, Tyler, Sittampalam, G Sitta, Simeonov, Anton, Hall, Matthew D
Published in Pharmacological reviews (01.10.2017)
Published in Pharmacological reviews (01.10.2017)
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Journal Article
A Perspective on Innovating the Chemistry Lab Bench
Godfrey, Alexander G, Michael, Samuel G, Sittampalam, Gurusingham Sitta, Zahoránszky-Köhalmi, Gergely
Published in Frontiers in robotics and AI (25.02.2020)
Published in Frontiers in robotics and AI (25.02.2020)
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Journal Article
Mapping biologically active chemical space to accelerate drug discovery
Sittampalam, G. Sitta, Rudnicki, Dobrila D., Tagle, Danilo A., Simeonov, Anton, Austin, Christopher P.
Published in Nature reviews. Drug discovery (01.02.2019)
Published in Nature reviews. Drug discovery (01.02.2019)
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Journal Article
Assay Guidance Manual for Drug Discovery: Robust or Go Bust
Markossian, Sarine, Coussens, Nathan P., Dahlin, Jayme L., Sittampalam, G. Sitta
Published in SLAS discovery (01.12.2021)
Published in SLAS discovery (01.12.2021)
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Journal Article
Preclinical target validation for non-addictive therapeutics development for pain
Hargreaves, Richard, Akinsanya, Karen, Ajit, Seena K, Dhruv, Neel T, Driscoll, Jamie, Farina, Peter, Gavva, Narender, Gill, Marie, Houghton, Andrea, Iyengar, Smriti, Jones, Carrie, Kavelaars, Annemieke, Kaykas, Ajamete, Koroshetz, Walter J, Laeng, Pascal, Laird, Jennifer M, Lo, Donald C, Luthman, Johan, Munro, Gordon, Oshinsky, Michael L, Sittampalam, G Sitta, Woller, Sarah A, Tamiz, Amir P
Published in Expert opinion on therapeutic targets (02.09.2022)
Published in Expert opinion on therapeutic targets (02.09.2022)
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Journal Article
Development of a fluorescence resonance energy transfer assay for measuring the activity of Streptococcus pneumoniae DNA ligase, an enzyme essential for DNA replication, repair, and recombination
Cynthia Chen, Xinyi, Hentz, Nathaniel G, Hubbard, Fredrick, Meier, Timothy I, Sittampalam, Sitta, Zhao, Genshi
Published in Analytical biochemistry (15.10.2002)
Published in Analytical biochemistry (15.10.2002)
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