Discovery of 6‑Amino-2-{[(1S)‑1-methylbutyl]oxy}-9-[5-(1-piperidinyl)pentyl]-7,9-dihydro‑8H‑purin-8-one (GSK2245035), a Highly Potent and Selective Intranasal Toll-Like Receptor 7 Agonist for the Treatment of Asthma
Biggadike, Keith, Ahmed, Mahbub, Ball, Doug I, Coe, Diane M, Dalmas Wilk, Deidre A, Edwards, Chris D, Gibbon, Bob H, Hardy, Charlotte J, Hermitage, Stephen A, Hessey, Joanne O, Hillegas, Aimee E, Hughes, Stephen C, Lazarides, Linos, Lewell, Xiao Q, Lucas, Amanda, Mallett, David N, Price, Mark A, Priest, Fiona M, Quint, Diana J, Shah, Poonam, Sitaram, Anesh, Smith, Stephen A, Stocker, Richard, Trivedi, Naimisha A, Tsitoura, Daphne C, Weller, Victoria
Published in Journal of medicinal chemistry (10.03.2016)
Published in Journal of medicinal chemistry (10.03.2016)
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Journal Article
Delivering an Automated and Integrated Approach to Combination Screening Using Acoustic-Droplet Technology
Cross, Kevin, Craggs, Richard, Swift, Denise, Sitaram, Anesh, Daya, Sandeep, Roberts, Mark, Hawley, Shaun, Owen, Paul, Isherwood, Bev
Published in Journal of Laboratory Automation (01.02.2016)
Published in Journal of Laboratory Automation (01.02.2016)
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Journal Article
Discovery of 6-Amino-2-{[(1 S )-1-methylbutyl]oxy}-9-[5-(1-piperidinyl)pentyl]-7,9-dihydro-8 H -purin-8-one (GSK2245035), a Highly Potent and Selective Intranasal Toll-Like Receptor 7 Agonist for the Treatment of Asthma
Biggadike, Keith, Ahmed, Mahbub, Ball, Doug I., Coe, Diane M., Dalmas Wilk, Deidre A., Edwards, Chris D., Gibbon, Bob H., Hardy, Charlotte J., Hermitage, Stephen A., Hessey, Joanne O., Hillegas, Aimee E., Hughes, Stephen C., Lazarides, Linos, Lewell, Xiao Q., Lucas, Amanda, Mallett, David N., Price, Mark A., Priest, Fiona M., Quint, Diana J., Shah, Poonam, Sitaram, Anesh, Smith, Stephen A., Stocker, Richard, Trivedi, Naimisha A., Tsitoura, Daphne C., Weller, Victoria
Published in Journal of medicinal chemistry (10.03.2016)
Published in Journal of medicinal chemistry (10.03.2016)
Get full text
Journal Article