Pharmacological Activation of Nrf2 Enhances Functional Liver Regeneration
Chan, Benjamin K.Y., Elmasry, Mohamed, Forootan, Shiva S., Russomanno, Giusy, Bunday, Tobias M., Zhang, Fang, Brillant, Nathalie, Starkey Lewis, Philip J., Aird, Rhona, Ricci, Emanuele, Andrews, Timothy D., Sison‐Young, Rowena L., Schofield, Amy L., Fang, Yongxiang, Lister, Adam, Sharkey, Jack W., Poptani, Harish, Kitteringham, Neil R., Forbes, Stuart J., Malik, Hassan Z., Fenwick, Stephen W., Park, B. Kevin, Goldring, Christopher E., Copple, Ian M.
Published in Hepatology (Baltimore, Md.) (01.08.2021)
Published in Hepatology (Baltimore, Md.) (01.08.2021)
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Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease
Bell, Catherine C, Hendriks, Delilah F G, Moro, Sabrina M L, Ellis, Ewa, Walsh, Joanne, Renblom, Anna, Fredriksson Puigvert, Lisa, Dankers, Anita C A, Jacobs, Frank, Snoeys, Jan, Sison-Young, Rowena L, Jenkins, Rosalind E, Nordling, Åsa, Mkrtchian, Souren, Park, B Kevin, Kitteringham, Neil R, Goldring, Christopher E P, Lauschke, Volker M, Ingelman-Sundberg, Magnus
Published in Scientific reports (04.05.2016)
Published in Scientific reports (04.05.2016)
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Journal Article
Donor‐Dependent and Other Nondefined Factors have Greater Influence on the Hepatic Phenotype than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte‐Like Cells
Heslop, James A., Kia, Richard, Pridgeon, Christopher S., Sison‐Young, Rowena L., Liloglou, Triantafillos, Elmasry, Mohamed, Fenwick, Stephen W., Mills, John S., Kitteringham, Neil R., Goldring, Chris E., Park, B. Kevin
Published in Stem cells translational medicine (01.08.2017)
Published in Stem cells translational medicine (01.08.2017)
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Journal Article
Comparative Proteomic Characterization of 4 Human Liver-Derived Single Cell Culture Models Reveals Significant Variation in the Capacity for Drug Disposition, Bioactivation, and Detoxication
Sison-Young, Rowena L C, Mitsa, Dimitra, Jenkins, Rosalind E, Mottram, David, Alexandre, Eliane, Richert, Lysiane, Aerts, Hélène, Weaver, Richard J, Jones, Robert P, Johann, Esther, Hewitt, Philip G, Ingelman-Sundberg, Magnus, Goldring, Christopher E P, Kitteringham, Neil R, Park, B Kevin
Published in Toxicological sciences (01.10.2015)
Published in Toxicological sciences (01.10.2015)
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Journal Article
Donor‐Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte‐Like Cells
Heslop, James A., Kia, Richard, Pridgeon, Christopher S., Sison‐Young, Rowena L., Liloglou, Triantafillos, Elmasry, Mohamed, Fenwick, Stephen W., Mills, John S., Kitteringham, Neil R., Goldring, Chris E., Park, B. Kevin
Published in Stem cells translational medicine (01.05.2017)
Published in Stem cells translational medicine (01.05.2017)
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Journal Article
MicroRNA-122: a novel hepatocyte-enriched in vitro marker of drug-induced cellular toxicity
Kia, Richard, Kelly, Lorna, Sison-Young, Rowena L C, Zhang, Fang, Pridgeon, Chris S, Heslop, James A, Metcalfe, Pete, Kitteringham, Neil R, Baxter, Melissa, Harrison, Sean, Hanley, Neil A, Burke, Zoë D, Storm, Mike P, Welham, Melanie J, Tosh, David, Küppers-Munther, Barbara, Edsbagge, Josefina, Starkey Lewis, Philip J, Bonner, Frank, Harpur, Ernie, Sidaway, James, Bowes, Joanne, Fenwick, Stephen W, Malik, Hassan, Goldring, Chris E P, Park, B Kevin
Published in Toxicological sciences (01.03.2015)
Published in Toxicological sciences (01.03.2015)
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Journal Article
Cellular Uptake of the Atypical Antipsychotic Clozapine Is a Carrier-Mediated Process
Dickens, David, Rädisch, Steffen, Chiduza, George N, Giannoudis, Athina, Cross, Michael J, Malik, Hassan, Schaeffeler, Elke, Sison-Young, Rowena L, Wilkinson, Emma L, Goldring, Christopher E, Schwab, Matthias, Pirmohamed, Munir, Nies, Anne T
Published in Molecular pharmaceutics (06.08.2018)
Published in Molecular pharmaceutics (06.08.2018)
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Journal Article
A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity
Sison-Young, Rowena L., Lauschke, Volker M., Johann, Esther, Alexandre, Eliane, Antherieu, Sébastien, Aerts, Hélène, Gerets, Helga H. J., Labbe, Gilles, Hoët, Delphine, Dorau, Martina, Schofield, Christopher A., Lovatt, Cerys A., Holder, Julie C., Stahl, Simone H., Richert, Lysiane, Kitteringham, Neil R., Jones, Robert P., Elmasry, Mohamed, Weaver, Richard J., Hewitt, Philip G., Ingelman-Sundberg, Magnus, Goldring, Chris E., Park, B. Kevin
Published in Archives of toxicology (01.03.2017)
Published in Archives of toxicology (01.03.2017)
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Journal Article
Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms
Pridgeon, Chris S., Schlott, Constanze, Wong, Min Wei, Heringa, Minne B., Heckel, Tobias, Leedale, Joe, Launay, Laurence, Gryshkova, Vitalina, Przyborski, Stefan, Bearon, Rachel N., Wilkinson, Emma L., Ansari, Tahera, Greenman, John, Hendriks, Delilah F. G., Gibbs, Sue, Sidaway, James, Sison-Young, Rowena L., Walker, Paul, Cross, Mike J., Park, B. Kevin, Goldring, Chris E. P.
Published in Archives of toxicology (01.02.2018)
Published in Archives of toxicology (01.02.2018)
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Journal Article
A multicenter assessment of single-cell models aligned to standard measures of cell health for prediction of acute hepatotoxicity
Sison-Young, Rowena L., Lauschke, Volker M., Johann, Esther, Alexandre, Eliane, Antherieu, Sébastien, Aerts, Hélène, Gerets, Helga H. J., Labbe, Gilles, Hoët, Delphine, Dorau, Martina, Schofield, Christopher A., Lovatt, Cerys A., Holder, Julie C., Stahl, Simone H., Richert, Lysiane, Kitteringham, Neil R., Jones, Robert P., Elmasry, Mohamed, Weaver, Richard J., Hewitt, Philip G., Ingelman-Sundberg, Magnus, Goldring, Chris E., Park, B. Kevin
Published in Archives of toxicology (01.03.2017)
Published in Archives of toxicology (01.03.2017)
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Journal Article