Developing better mouse models to study cisplatin-induced kidney injury
Sharp, Cierra N, Siskind, Leah J
Published in American journal of physiology. Renal physiology (01.10.2017)
Published in American journal of physiology. Renal physiology (01.10.2017)
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Sphingolipid Metabolism Cooperates with BAK and BAX to Promote the Mitochondrial Pathway of Apoptosis
Chipuk, Jerry E., McStay, Gavin P., Bharti, Archana, Kuwana, Tomomi, Clarke, Christopher J., Siskind, Leah J., Obeid, Lina M., Green, Douglas R.
Published in Cell (02.03.2012)
Published in Cell (02.03.2012)
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Subclinical kidney injury induced by repeated cisplatin administration results in progressive chronic kidney disease
Sharp, Cierra N, Doll, Mark A, Megyesi, Judit, Oropilla, Gabrielle B, Beverly, Levi J, Siskind, Leah J
Published in American journal of physiology. Renal physiology (01.07.2018)
Published in American journal of physiology. Renal physiology (01.07.2018)
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Repeated administration of low-dose cisplatin in mice induces fibrosis
Sharp, Cierra N, Doll, Mark A, Dupre, Tess V, Shah, Parag P, Subathra, Marimuthu, Siow, Deanna, Arteel, Gavin E, Megyesi, Judit, Beverly, Levi J, Siskind, Leah J
Published in American journal of physiology. Renal physiology (15.03.2016)
Published in American journal of physiology. Renal physiology (15.03.2016)
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BAK activation is necessary and sufficient to drive ceramide synthase-dependent ceramide accumulation following inhibition of BCL2-like proteins
Beverly, Levi J, Howell, Lauren A, Hernandez-Corbacho, Maria, Casson, Lavona, Chipuk, Jerry E, Siskind, Leah J
Published in Biochemical journal (15.05.2013)
Published in Biochemical journal (15.05.2013)
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Kidney glycosphingolipids are elevated early in diabetic nephropathy and mediate hypertrophy of mesangial cells
Subathra, Marimuthu, Korrapati, Midhun, Howell, Lauren A, Arthur, John M, Shayman, James A, Schnellmann, Rick G, Siskind, Leah J
Published in American journal of physiology. Renal physiology (01.08.2015)
Published in American journal of physiology. Renal physiology (01.08.2015)
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Mutant and curli-producing E. coli enhance the disease phenotype in a hSOD1-G93A mouse model of ALS
Kurlawala, Zimple, McMillan, Joseph D., Singhal, Richa A., Morehouse, Johnny, Burke, Darlene A., Sears, Sophia M., Duregon, Eleonora, Beverly, Levi J., Siskind, Leah J., Friedland, Robert P.
Published in Scientific reports (12.04.2023)
Published in Scientific reports (12.04.2023)
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Neutral ceramidase deficiency protects against cisplatin-induced acute kidney injury
Sears, Sophia M., Dupre, Tess V., Shah, Parag P., Davis, Deanna L., Doll, Mark A., Sharp, Cierra N., Vega, Alexis A., Megyesi, Judit, Beverly, Levi J., Snider, Ashley J., Obeid, Lina M., Hannun, Yusuf A., Siskind, Leah J.
Published in Journal of lipid research (01.03.2022)
Published in Journal of lipid research (01.03.2022)
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Towards a molecular understanding of the overlapping and distinct roles of UBQLN1 and UBQLN2 in lung cancer progression and metastasis
Shah, Parag P., Saurabh, Kumar, Kurlawala, Zimple, Vega, Alexis A., Siskind, Leah J., Beverly, Levi J.
Published in Neoplasia (New York, N.Y.) (01.03.2022)
Published in Neoplasia (New York, N.Y.) (01.03.2022)
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Ceramide starves cells to death by downregulating nutrient transporter proteins
Guenther, Garret G, Peralta, Eigen R, Rosales, Kimberly Romero, Wong, Susan Y, Siskind, Leah J, Edinger, Aimee L
Published in Proceedings of the National Academy of Sciences - PNAS (11.11.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (11.11.2008)
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Fibroblast-Derived Extracellular Matrices: An Alternative Cell Culture System That Increases Metastatic Cellular Properties
Scherzer, Michael T, Waigel, Sabine, Donninger, Howard, Arumugam, Vennila, Zacharias, Wolfgang, Clark, Geoffrey, Siskind, Leah J, Soucy, Patricia, Beverly, Levi
Published in PloS one (15.09.2015)
Published in PloS one (15.09.2015)
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The BCL-2 Protein BAK Is Required for Long-chain Ceramide Generation during Apoptosis
Siskind, Leah J., Mullen, Thomas D., Romero Rosales, Kimberly, Clarke, Christopher J., Hernandez-Corbacho, María José, Edinger, Aimee L., Obeid, Lina M.
Published in The Journal of biological chemistry (16.04.2010)
Published in The Journal of biological chemistry (16.04.2010)
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Inhibiting glucosylceramide synthase exacerbates cisplatin-induced acute kidney injury
Dupre, Tess V., Doll, Mark A., Shah, Parag P., Sharp, Cierra N., Siow, Deanna, Megyesi, Judit, Shayman, James, Bielawska, Alicja, Bielawski, Jacek, Beverly, Levi J., Hernandez-Corbacho, Maria, Clarke, Christopher J., Snider, Ashley J., Schnellmann, Rick G., Obeid, Lina M., Hannun, Yusuf A., Siskind, Leah J.
Published in Journal of lipid research (01.07.2017)
Published in Journal of lipid research (01.07.2017)
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Loss of neutral ceramidase protects cells from nutrient- and energy -deprivation-induced cell death
Sundaram, Kumaran, Mather, Andrew R, Marimuthu, Subathra, Shah, Parag P, Snider, Ashley J, Obeid, Lina M, Hannun, Yusuf A, Beverly, Levi J, Siskind, Leah J
Published in Biochemical journal (15.03.2016)
Published in Biochemical journal (15.03.2016)
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