Pharmacological inhibition of lysosomal two-pore channel 2 (TPC2) confers neuroprotection in stroke via autophagy regulation
Tedeschi, Valentina, Vinciguerra, Antonio, Sisalli, Maria Josè, Pignataro, Giuseppe, Secondo, Agnese
Published in Neurobiology of disease (01.03.2023)
Published in Neurobiology of disease (01.03.2023)
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Inhibition of autophagy by chloroquine prevents resistance to PI3K/AKT inhibitors and potentiates their antitumor effect in combination with paclitaxel in triple negative breast cancer models
Cocco, Stefania, Leone, Alessandra, Roca, Maria Serena, Lombardi, Rita, Piezzo, Michela, Caputo, Roberta, Ciardiello, Chiara, Costantini, Susan, Bruzzese, Francesca, Sisalli, Maria José, Budillon, Alfredo, De Laurentiis, Michelino
Published in Journal of translational medicine (27.06.2022)
Published in Journal of translational medicine (27.06.2022)
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Journal Article
Ultrafine particulate matter pollution and dysfunction of endoplasmic reticulum Ca2+ store: A pathomechanism shared with amyotrophic lateral sclerosis motor neurons?
Sapienza, Silvia, Tedeschi, Valentina, Apicella, Barbara, Pannaccione, Anna, Russo, Carmela, Sisalli, Maria Josè, Magliocca, Giorgia, Loffredo, Stefania, Secondo, Agnese
Published in Ecotoxicology and environmental safety (15.03.2024)
Published in Ecotoxicology and environmental safety (15.03.2024)
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Editorial: Advances in brain disorders: from mechanisms to therapeutic targets
Bono, Federica, Abate, Giulia, Bonini, Sara Anna, Sisalli, Maria Josè, Bellucci, Arianna
Published in Frontiers in molecular neuroscience (28.11.2023)
Published in Frontiers in molecular neuroscience (28.11.2023)
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Journal Article
The 3-(3-oxoisoindolin-1-yl)pentane-2,4-dione (ISOAC1) as a new molecule able to inhibit Amyloid β aggregation and neurotoxicity
Piccialli, Ilaria, Greco, Francesca, Roviello, Giovanni, Sisalli, Maria Josè, Tedeschi, Valentina, di Mola, Antonia, Borbone, Nicola, Oliviero, Giorgia, De Feo, Vincenzo, Secondo, Agnese, Massa, Antonio, Pannaccione, Anna
Published in Biomedicine & pharmacotherapy (01.12.2023)
Published in Biomedicine & pharmacotherapy (01.12.2023)
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Journal Article
Ncx3-Induced Mitochondrial Dysfunction in Midbrain Leads to Neuroinflammation in Striatum of A53t-α-Synuclein Transgenic Old Mice
Di Martino, Rossana, Sisalli, Maria, Sirabella, Rossana, Della Notte, Salvatore, Borzacchiello, Domenica, Feliciello, Antonio, Annunziato, Lucio, Scorziello, Antonella
Published in International journal of molecular sciences (01.08.2021)
Published in International journal of molecular sciences (01.08.2021)
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Journal Article
Age-Related Changes in D-Aspartate Oxidase Promoter Methylation Control Extracellular D-Aspartate Levels and Prevent Precocious Cell Death during Brain Aging
Punzo, Daniela, Errico, Francesco, Cristino, Luigia, Sacchi, Silvia, Keller, Simona, Belardo, Carmela, Luongo, Livio, Nuzzo, Tommaso, Imperatore, Roberta, Florio, Ermanno, De Novellis, Vito, Affinito, Ornella, Migliarini, Sara, Maddaloni, Giacomo, Sisalli, Maria Josè, Pasqualetti, Massimo, Pollegioni, Loredano, Maione, Sabatino, Chiariotti, Lorenzo, Usiello, Alessandro
Published in The Journal of neuroscience (09.03.2016)
Published in The Journal of neuroscience (09.03.2016)
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Journal Article
Oxidative Metabolism in Brain Ischemia and Preconditioning: Two Sides of the Same Coin
D'Apolito, Elena, Sisalli, Maria Josè, Tufano, Michele, Annunziato, Lucio, Scorziello, Antonella
Published in Antioxidants (01.05.2024)
Published in Antioxidants (01.05.2024)
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Journal Article
Knocking-out the Siah2 E3 ubiquitin ligase prevents mitochondrial NCX3 degradation, regulates mitochondrial fission and fusion, and restores mitochondrial function in hypoxic neurons
Sisalli, Maria Josè, Ianniello, Gaetano, Savoia, Claudia, Cuomo, Ornella, Annunziato, Lucio, Scorziello, Antonella
Published in Cell communication and signaling (12.03.2020)
Published in Cell communication and signaling (12.03.2020)
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Anti-miRNA103/107 encapsulated in transferrin-conjugated lipid nanoparticles crosses blood-brain barrier and reduces brain ischemic damage
Cepparulo, Pasquale, Cuomo, Ornella, Campani, Virginia, Vinciguerra, Antonio, Sisalli, Maria Josè, Nele, Valeria, Anzilotti, Serenella, Valsecchi, Valeria, Casamassa, Antonella, Brancaccio, Paola, Scorziello, Antonella, De Rosa, Giuseppe, Annunziato, Lucio, Pignataro, Giuseppe
Published in Molecular therapy. Nucleic acids (12.03.2024)
Published in Molecular therapy. Nucleic acids (12.03.2024)
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Journal Article
Increased KV2.1 Channel Clustering Underlies the Reduction of Delayed Rectifier K+ Currents in Hippocampal Neurons of the Tg2576 Alzheimer’s Disease Mouse
Piccialli, Ilaria, Sisalli, Maria José, de Rosa, Valeria, Boscia, Francesca, Tedeschi, Valentina, Secondo, Agnese, Pannaccione, Anna
Published in Cells (Basel, Switzerland) (09.09.2022)
Published in Cells (Basel, Switzerland) (09.09.2022)
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Involvement of the Na+/Ca2+ exchanger isoform 1 (NCX1) in Neuronal Growth Factor (NGF)-induced Neuronal Differentiation through Ca2+-dependent Akt Phosphorylation
Secondo, Agnese, Esposito, Alba, Sirabella, Rossana, Boscia, Francesca, Pannaccione, Anna, Molinaro, Pasquale, Cantile, Maria, Ciccone, Roselia, Sisalli, Maria Josè, Scorziello, Antonella, Di Renzo, Gianfranco, Annunziato, Lucio
Published in The Journal of biological chemistry (16.01.2015)
Published in The Journal of biological chemistry (16.01.2015)
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Journal Article
L-Ornithine L-Aspartate Restores Mitochondrial Function and Modulates Intracellular Calcium Homeostasis in Parkinson’s Disease Models
Sisalli, Maria Josè, Della Notte, Salvatore, Secondo, Agnese, Ventra, Carmelo, Annunziato, Lucio, Scorziello, Antonella
Published in Cells (Basel, Switzerland) (01.09.2022)
Published in Cells (Basel, Switzerland) (01.09.2022)
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NCX1 Is a Novel Target Gene for Hypoxia-Inducible Factor-1 in Ischemic Brain Preconditioning
VALSECCHI, Valeria, PIGNATARO, Giuseppe, DI RENZO, Gianfranco, ANNUNZIATO, Lucio, DEL PRETE, Annalisa, SIRABELLA, Rossana, MATRONE, Carmela, BOSCIA, Francesca, SCORZIELLO, Antonella, SISALLI, Maria Josè, ESPOSITO, Elga, ZAMBRANO, Nicola
Published in Stroke (1970) (01.03.2011)
Published in Stroke (1970) (01.03.2011)
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Tracking the evolution of epialleles during neural differentiation and brain development: D-Aspartate oxidase as a model gene
Florio, Ermanno, Keller, Simona, Coretti, Lorena, Affinito, Ornella, Scala, Giovanni, Errico, Francesco, Fico, Annalisa, Boscia, Francesca, Sisalli, Maria Josè, Reccia, Mafalda Giovanna, Miele, Gennaro, Monticelli, Antonella, Scorziello, Antonella, Lembo, Francesca, Colucci-D'Amato, Luca, Minchiotti, Gabriella, Avvedimento, Vittorio Enrico, Usiello, Alessandro, Cocozza, Sergio, Chiariotti, Lorenzo
Published in Epigenetics (02.01.2017)
Published in Epigenetics (02.01.2017)
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Pharmacological Characterization of the Newly Synthesized 5‑Amino‑N‑butyl-2-(4-ethoxyphenoxy)-benzamide Hydrochloride (BED) as a Potent NCX3 Inhibitor That Worsens Anoxic Injury in Cortical Neurons, Organotypic Hippocampal Cultures, and Ischemic Brain
Secondo, Agnese, Pignataro, Giuseppe, Ambrosino, Paolo, Pannaccione, Anna, Molinaro, Pasquale, Boscia, Francesca, Cantile, Maria, Cuomo, Ornella, Esposito, Alba, Sisalli, Maria Josè, Scorziello, Antonella, Guida, Natascia, Anzilotti, Serenella, Fiorino, Ferdinando, Severino, Beatrice, Santagada, Vincenzo, Caliendo, Giuseppe, Di Renzo, Gianfranco, Annunziato, Lucio
Published in ACS chemical neuroscience (19.08.2015)
Published in ACS chemical neuroscience (19.08.2015)
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Journal Article
Lysosomal calcium is modulated by STIM1/TRPML1 interaction which participates to neuronal survival during ischemic preconditioning
Tedeschi, Valentina, Sisalli, Maria José, Petrozziello, Tiziana, Canzoniero, Lorella Maria Teresa, Secondo, Agnese
Published in The FASEB journal (01.02.2021)
Published in The FASEB journal (01.02.2021)
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Journal Article
The activation of Mucolipin TRP channel 1 (TRPML1) protects motor neurons from L-BMAA neurotoxicity by promoting autophagic clearance
Tedeschi, Valentina, Petrozziello, Tiziana, Sisalli, Maria José, Boscia, Francesca, Canzoniero, Lorella Maria Teresa, Secondo, Agnese
Published in Scientific reports (24.07.2019)
Published in Scientific reports (24.07.2019)
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Na+/Ca2+ exchanger isoform 1 (NCX1) and canonical transient receptor potential channel 6 (TRPC6) are recruited by STIM1 to mediate Store-Operated Calcium Entry in primary cortical neurons
Tedeschi, Valentina, Sisalli, Maria Josè, Pannaccione, Anna, Piccialli, Ilaria, Molinaro, Pasquale, Annunziato, Lucio, Secondo, Agnese
Published in Cell calcium (Edinburgh) (01.01.2022)
Published in Cell calcium (Edinburgh) (01.01.2022)
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Nuclear-encoded NCX3 and AKAP121: Two novel modulators of mitochondrial calcium efflux in normoxic and hypoxic neurons
Sisalli, Maria Josè, Feliciello, Antonio, Della Notte, Salvatore, Di Martino, Rossana, Borzacchiello, Domenica, Annunziato, Lucio, Scorziello, Antonella
Published in Cell calcium (Edinburgh) (01.05.2020)
Published in Cell calcium (Edinburgh) (01.05.2020)
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