Protein conformational flexibility modulates kinetics and thermodynamics of drug binding
Amaral, M., Kokh, D. B., Bomke, J., Wegener, A., Buchstaller, H. P., Eggenweiler, H. M., Matias, P., Sirrenberg, C., Wade, R. C., Frech, M.
Published in Nature communications (22.12.2017)
Published in Nature communications (22.12.2017)
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M3814, a DNA-dependent Protein Kinase Inhibitor (DNA-PKi), Potentiates the Effect of Ionizing Radiation (IR) in Xenotransplanted Tumors in Nude Mice
Damstrup, L, Zimmerman, A, Sirrenberg, C, Zenke, F, Vassilev, L
Published in International journal of radiation oncology, biology, physics (15.03.2016)
Published in International journal of radiation oncology, biology, physics (15.03.2016)
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A Novel Strategy for ADME Screening of Prodrugs: Combined Use of Serum and Hepatocytes to Integrate Bioactivation and Clearance, and Predict Exposure to Both Active and Prodrug to the Systemic Circulation
Hoppe, Edmund, Hewitt, Nicola J., Buchstaller, Hans-Peter, Eggenweiler, Hans-Michael, Sirrenberg, Christian, Zimmermann, Astrid, März, Joachim, Schwartz, Harry, Saal, Christoph, Meyring, Michael, Hecht, Stefan
Published in Journal of pharmaceutical sciences (01.05.2014)
Published in Journal of pharmaceutical sciences (01.05.2014)
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Journal Article
Role of Tim23 as Voltage Sensor and Presequence Receptor in Protein Import into Mitochondria
Bauer, Matthias F, Sirrenberg, Christian, Neupert, Walter, Brunner, Michael
Published in Cell (04.10.1996)
Published in Cell (04.10.1996)
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Journal Article
Import of carrier proteins into the mitochondrial inner membrane mediated by Tim22
Sirrenberg, Christian, Bauer, Matthias F, Guiard, Bernard, Neupert, Walter, Brunner, Michael
Published in Nature (London) (12.12.1996)
Published in Nature (London) (12.12.1996)
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Journal Article
Biogenesis of Tim23 and Tim17, integral components of the TIM machinery for matrix-targeted preproteins
Kaldi, K, Bauer, M.F, Sirrenberg, C, Neupert, W, Brunner, M
Published in The EMBO journal (16.03.1998)
Published in The EMBO journal (16.03.1998)
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Journal Article
The TIM17 super(.)23 preprotein translocase of mitochondria: composition and function in protein transport into the matrix
Moro, F, Sirrenberg, C, Schneider, H, Neupert, W, Brunner, M
Published in The EMBO journal (01.07.1999)
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Published in The EMBO journal (01.07.1999)
Journal Article
Functional Cooperation and Stoichiometry of Protein Translocases of the Outer and Inner Membranes of Mitochondria
Sirrenberg, Christian, Endres, Maxi, Becker, Karin, Bauer, Matthias F., Walther, Ernst, Neupert, Walter, Brunner, Michael
Published in The Journal of biological chemistry (21.11.1997)
Published in The Journal of biological chemistry (21.11.1997)
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Journal Article
The TIM17.23 preprotein translocase of mitochondria: composition and function in protein transport into the matrix
Moro, F, Sirrenberg, C, Schneider, H C, Neupert, W, Brunner, M
Published in The EMBO journal (01.07.1999)
Published in The EMBO journal (01.07.1999)
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Journal Article
Tim9, a new component of the TIM22 super(.)54 translocase in mitochondria
Adam, A, Endres, M, Sirrenberg, C, Lottspeich, F, Neupert, W, Brunner, M
Published in The EMBO journal (15.01.1999)
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Published in The EMBO journal (15.01.1999)
Journal Article
Tim9, a new component of the TIM22.54 translocase in mitochondria
Adam, A, Endres, M, Sirrenberg, C, Lottspeich, F, Neupert, W, Brunner, M
Published in The EMBO journal (15.01.1999)
Published in The EMBO journal (15.01.1999)
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