α-Thujone (the active component of absinthe): γ-Aminobutyric acid type A receptor modulation and metabolic detoxification
Höld, Karin M., Sirisoma, Nilantha S., Ikeda, Tomoko, Narahashi, Toshio, Casida, John E.
Published in Proceedings of the National Academy of Sciences - PNAS (11.04.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (11.04.2000)
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A Role for Transferrin Receptor in Triggering Apoptosis When Targeted with Gambogic Acid
Kasibhatla, Shailaja, Jessen, Katayoun A, Maliartchouk, Sergei, Wang, Jean Yu, English, Nicole M, Drewe, John, Qiu, Ling, Archer, Shannon P, Ponce, Anthony E, Sirisoma, Nilantha, Jiang, Songchun, Zhang, Han-Zhong, Gehlsen, Kurt R, Cai, Sui Xiong, Green, Douglas R, Tseng, Ben
Published in Proceedings of the National Academy of Sciences - PNAS (23.08.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (23.08.2005)
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Discovery of 1-benzoyl-3-cyanopyrrolo[1,2-a]quinolines as a new series of apoptosis inducers using a cell-and caspase-based high-throughput screening assay. Part 1: Structure-activity relationships of the 1-and 3-positions
KEMNITZER, William, KUEMMERLE, Jared, SONGCHUN JIANG, ZHANG, Han-Zhong, SIRISOMA, Nilantha, KASIBHATLA, Shailaja, CROGAN-GRUNDY, Candace, TSENG, Ben, DREWE, John, SUI XIONG CAI
Published in Bioorganic & medicinal chemistry letters (01.12.2008)
Published in Bioorganic & medicinal chemistry letters (01.12.2008)
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Discovery of 4-anilino- N-methylthieno[3,2- d]pyrimidines and 4-anilino- N-methylthieno[2,3- d]pyrimidines as potent apoptosis inducers
Kemnitzer, William, Sirisoma, Nilantha, May, Chris, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry letters (01.07.2009)
Published in Bioorganic & medicinal chemistry letters (01.07.2009)
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The Natural Polyamine Spermine Functions Directly as a Free Radical Scavenger
Ha, Hyo Chol, Sirisoma, Nilantha S., Kuppusamy, Periannan, Zweier, Jay L., Woster, Patrick M., Casero, Robert A.
Published in Proceedings of the National Academy of Sciences - PNAS (15.09.1998)
Published in Proceedings of the National Academy of Sciences - PNAS (15.09.1998)
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Discovery of substituted N′-(2-oxoindolin-3-ylidene)benzohydrazides as new apoptosis inducers using a cell- and caspase-based HTS assay
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Published in Bioorganic & medicinal chemistry letters (15.05.2009)
Published in Bioorganic & medicinal chemistry letters (15.05.2009)
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Discovery of N-methyl-4-(4-methoxyanilino)quinazolines as potent apoptosis inducers. Structure–activity relationship of the quinazoline ring
Sirisoma, Nilantha, Pervin, Azra, Zhang, Hong, Jiang, Songchun, Adam Willardsen, J., Anderson, Mark B., Mather, Gary, Pleiman, Christopher M., Kasibhatla, Shailaja, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry letters (01.04.2010)
Published in Bioorganic & medicinal chemistry letters (01.04.2010)
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Detoxification of α- and β-Thujones (the Active Ingredients of Absinthe): Site Specificity and Species Differences in Cytochrome P450 Oxidation in Vitro and in Vivo
Höld, Karin M, Sirisoma, Nilantha S, Casida, John E
Published in Chemical research in toxicology (01.05.2001)
Published in Chemical research in toxicology (01.05.2001)
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Discovery of N-(4-Methoxyphenyl)-N,2-dimethylquinazolin-4-amine, a Potent Apoptosis Inducer and Efficacious Anticancer Agent with High Blood Brain Barrier Penetration
Sirisoma, Nilantha, Pervin, Azra, Zhang, Hong, Jiang, Songchun, Willardsen, J. Adam, Anderson, Mark B, Mather, Gary, Pleiman, Christopher M, Kasibhatla, Shailaja, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Journal of medicinal chemistry (23.04.2009)
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Abstract 4851: Potent cell cycle inhibitors suitable for treatment of multidrug-resistant tumors
Sivaraja, Mohan, Sizikov, Sivan, Sirisoma, Nilantha, Kirtadze, Tamari, Chattopadhyay, Madhuri, Ewald, Makena, Dash, Subhadra, Wong, Anne, Neckermann, Georg, To, Elaine, Chang, Stephanie, Shiau, Timothy P., Williams, David C., Short, Kevin M., Estiarte, Angels, Datta, Anirban, Kita, David B.
Published in Cancer research (Chicago, Ill.) (01.07.2018)
Published in Cancer research (Chicago, Ill.) (01.07.2018)
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MPC-6827 : A small-molecule inhibitor of microtubule formation that is not a substrate for multidrug resistance pumps
KASIBHATLA, Shailaja, BAICHWAL, Vijay, PERVIN, Azra, TSENG, Ben, CARLSON, Robert O, PLEIMAN, Christopher M, SUI XIONG CAI, ROTH, Bruce, SKVORTSOVA, Ira, SKVORTSOV, Sergej, LUKAS, Peter, ENGLISH, Nicole M, SIRISOMA, Nilantha, DREWE, John
Published in Cancer research (Chicago, Ill.) (15.06.2007)
Published in Cancer research (Chicago, Ill.) (15.06.2007)
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트롬빈 억제제, 제제, 및 그의 용도
SHORT KEVIN MICHAEL, KITA DAVID BEN, ESTIARTE MARTINEZ MARIA DE LOS ANGELES, SIRISOMA NILANTHA SUDATH
Year of Publication 30.06.2021
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Year of Publication 30.06.2021
Patent
Discovery of 1-benzoyl-3-cyanopyrrolo[1,2- a]quinolines as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2: Structure–activity relationships of the 4-, 5-, 6-, 7- and 8-positions
Kemnitzer, William, Kuemmerle, Jared, Jiang, Songchun, Sirisoma, Nilantha, Kasibhatla, Shailaja, Crogan-Grundy, Candace, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry letters (01.07.2009)
Published in Bioorganic & medicinal chemistry letters (01.07.2009)
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Discovery of 2-Chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine (EP128265, MPI-0441138) as a Potent Inducer of Apoptosis with High In Vivo Activity
Sirisoma, Nilantha, Kasibhatla, Shailaja, Pervin, Azra, Zhang, Hong, Jiang, Songchun, Willardsen, J. Adam, Anderson, Mark B, Baichwal, Vijay, Mather, Gary G, Jessing, Kevin, Hussain, Raouf, Hoang, Khanh, Pleiman, Christopher M, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Journal of medicinal chemistry (14.08.2008)
Published in Journal of medicinal chemistry (14.08.2008)
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Discovery of substituted 4-anilino-2-(2-pyridyl)pyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. Part 1: Structure–activity relationships of the 4-anilino group
Sirisoma, Nilantha, Kasibhatla, Shailaja, Nguyen, Bao, Pervin, Azra, Wang, Yang, Claassen, Gisela, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry (01.12.2006)
Published in Bioorganic & medicinal chemistry (01.12.2006)
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Discovery of N-aryl-9-oxo-9H-fluorene-1-carboxamides as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 1. Structure–activity relationships of the carboxamide group
Kemnitzer, William, Sirisoma, Nilantha, Nguyen, Bao, Jiang, Songchun, Kasibhatla, Shailaja, Crogan-Grundy, Candace, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry letters (01.06.2009)
Published in Bioorganic & medicinal chemistry letters (01.06.2009)
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Discovery of N-aryl-9-oxo-9H-fluorene-1-carboxamides as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure-activity relationships of the 9-oxo-9H-fluorene ring
KEMNITZER, William, SIRISOMA, Nilantha, SONGCHUN JIANG, KASIBHATLA, Shailaja, CROGAN-GRUNDY, Candace, TSENG, Ben, DREWE, John, SUI XIONG CAI
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
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Discovery of substituted 4-anilino-2-arylpyrimidines as a new series of apoptosis inducers using a cell- and caspase-based high throughput screening assay. 2. Structure–activity relationships of the 2-aryl group
Sirisoma, Nilantha, Pervin, Azra, Nguyen, Bao, Crogan-Grundy, Candace, Kasibhatla, Shailaja, Tseng, Ben, Drewe, John, Cai, Sui Xiong
Published in Bioorganic & medicinal chemistry letters (15.04.2009)
Published in Bioorganic & medicinal chemistry letters (15.04.2009)
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