Synchronization of Stochastic Ca²⁺ Release Units Creates a Rhythmic Ca²⁺ Clock in Cardiac Pacemaker Cells
Maltsev, Anna V, Maltsev, Victor A, Mikheev, Maxim, Maltseva, Larissa A, Sirenko, Syevda G, Lakatta, Edward G, Stern, Michael D
Published in Biophysical journal (19.01.2011)
Published in Biophysical journal (19.01.2011)
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A coupled-clock system drives the automaticity of human sinoatrial nodal pacemaker cells
Tsutsui, Kenta, Monfredi, Oliver J, Sirenko-Tagirova, Syevda G, Maltseva, Larissa A, Bychkov, Rostislav, Kim, Mary S, Ziman, Bruce D, Tarasov, Kirill V, Tarasova, Yelena S, Zhang, Jing, Wang, Mingyi, Maltsev, Alexander V, Brennan, Jaclyn A, Efimov, Igor R, Stern, Michael D, Maltsev, Victor A, Lakatta, Edward G
Published in Science signaling (12.06.2018)
Published in Science signaling (12.06.2018)
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Rhythmic beating of stem cell-derived cardiac cells requires dynamic coupling of electrophysiology and Ca cycling
Zahanich, Ihor, Sirenko, Syevda G, Maltseva, Larissa A, Tarasova, Yelena S, Spurgeon, Harold A, Boheler, Kenneth R, Stern, Michael D, Lakatta, Edward G, Maltsev, Victor A
Published in Journal of molecular and cellular cardiology (01.01.2011)
Published in Journal of molecular and cellular cardiology (01.01.2011)
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Action potential characterization in intact mouse heart: steady-state cycle length dependence and electrical restitution
Knollmann, Bjorn C, Schober, Tilmann, Petersen, Andreas O, Sirenko, Syevda G, Franz, Michael R
Published in American journal of physiology. Heart and circulatory physiology (01.01.2007)
Published in American journal of physiology. Heart and circulatory physiology (01.01.2007)
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F110I and R278C Troponin T Mutations That Cause Familial Hypertrophic Cardiomyopathy Affect Muscle Contraction in Transgenic Mice and Reconstituted Human Cardiac Fibers
Hernandez, Olga M., Szczesna-Cordary, Danuta, Knollmann, Björn C., Miller, Todd, Bell, Michael, Zhao, Jiaju, Sirenko, Syevda G., Diaz, Zoraida, Guzman, Georgianna, Xu, Yuanyuan, Wang, Ying, Kerrick, W. Glenn L., Potter, James D.
Published in The Journal of biological chemistry (04.11.2005)
Published in The Journal of biological chemistry (04.11.2005)
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Electrochemical Na+ and Ca2+ gradients drive coupled-clock regulation of automaticity of isolated rabbit sinoatrial nodal pacemaker cells
Sirenko, Syevda G, Maltsev, Victor A, Yaniv, Yael, Bychkov, Rostislav, Yaeger, Daniel, Vinogradova, Tatiana, Spurgeon, Harold A, Lakatta, Edward G
Published in American journal of physiology. Heart and circulatory physiology (01.07.2016)
Published in American journal of physiology. Heart and circulatory physiology (01.07.2016)
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Ca(2+)/calmodulin-activated phosphodiesterase 1A is highly expressed in rabbit cardiac sinoatrial nodal cells and regulates pacemaker function
Lukyanenko, Yevgeniya O, Younes, Antoine, Lyashkov, Alexey E, Tarasov, Kirill V, Riordon, Daniel R, Lee, Joonho, Sirenko, Syevda G, Kobrinsky, Evgeny, Ziman, Bruce, Tarasova, Yelena S, Juhaszova, Magdalena, Sollott, Steven J, Graham, David R, Lakatta, Edward G
Published in Journal of molecular and cellular cardiology (01.09.2016)
Published in Journal of molecular and cellular cardiology (01.09.2016)
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Journal Article
Ca2+/calmodulin-activated phosphodiesterase 1A is highly expressed in rabbit cardiac sinoatrial nodal cells and regulates pacemaker function
Lukyanenko, Yevgeniya O., Younes, Antoine, Lyashkov, Alexey E., Tarasov, Kirill V., Riordon, Daniel R., Lee, Joonho, Sirenko, Syevda G., Kobrinsky, Evgeny, Ziman, Bruce, Tarasova, Yelena S., Juhaszova, Magdalena, Sollott, Steven J., Graham, David R., Lakatta, Edward G.
Published in Journal of molecular and cellular cardiology (01.09.2016)
Published in Journal of molecular and cellular cardiology (01.09.2016)
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Isoproterenol Exacerbates a Long QT Phenotype in Kcnq1-Deficient Neonatal Mice: Possible Roles for Human-Like Kcnq1 Isoform 1 and Slow Delayed Rectifier K+ Current
Knollmann, Bjorn C, Casimiro, Mathew C, Katchman, Alexander N, Sirenko, Syevda G, Schober, Tilmann, Rong, Qi, Pfeifer, Karl, Ebert, Steven N
Published in The Journal of pharmacology and experimental therapeutics (01.07.2004)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2004)
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Targeted point mutagenesis of mouse Kcnq1: phenotypic analysis of mice with point mutations that cause Romano-Ward syndrome in humans
Casimiro, Mathew C., Knollmann, Bjoern C., Yamoah, Ebenezer N., Nie, Liping, Vary, Jay C., Sirenko, Syevda G., Greene, Anne E., Grinberg, Alexander, Huang, Sing Ping, Ebert, Steven N., Pfeifer, Karl
Published in Genomics (San Diego, Calif.) (01.09.2004)
Published in Genomics (San Diego, Calif.) (01.09.2004)
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Cyclosporine a treatment decreases left ventricular mass in mice expressing a FHC-linked troponin T (179N) mutation
Knollmann, Bioem C., Sirenko, Syevda G., Potter, James D., Horton, Kenneth, Weissman, Neil J.
Published in Journal of the American College of Cardiology (06.03.2002)
Published in Journal of the American College of Cardiology (06.03.2002)
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Electrochemical Na + and Ca 2+ gradients drive coupled-clock regulation of automaticity of isolated rabbit sinoatrial nodal pacemaker cells
Sirenko, Syevda G., Maltsev, Victor A., Yaniv, Yael, Bychkov, Rostislav, Yaeger, Daniel, Vinogradova, Tatiana, Spurgeon, Harold A., Lakatta, Edward G.
Published in American journal of physiology. Heart and circulatory physiology (01.07.2016)
Published in American journal of physiology. Heart and circulatory physiology (01.07.2016)
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Human AC8 Overexpression Increases the Ca2+ Mediated Ensemble and Imparts Improved Rhythmicity to the Sinoatrial Node In Vivo and Ex Vivo
Moen, Jack M., Matt, Michael G., Sirenko, Syevda G., Tarasov, Kirill V., Ahmet, Ismayil, Ramirez, Chris, Monfredi, Oliver, Tsutsui, Kenta, Ziman, Bruce, Yaniv, Yael, Lakatta, Edward G.
Published in Biophysical journal (03.02.2017)
Published in Biophysical journal (03.02.2017)
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Journal Article
Human AC8 Overexpression Increases the Ca 2+ Mediated Ensemble and Imparts Improved Rhythmicity to the Sinoatrial Node In Vivo and Ex Vivo
Moen, Jack M., Matt, Michael G., Sirenko, Syevda G., Tarasov, Kirill V., Ahmet, Ismayil, Ramirez, Chris, Monfredi, Oliver, Tsutsui, Kenta, Ziman, Bruce, Yaniv, Yael, Lakatta, Edward G.
Published in Biophysical journal (01.02.2017)
Published in Biophysical journal (01.02.2017)
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Journal Article
Ca 2 + /calmodulin - activated phosphodiesterase 1A is highly expressed in rabbit cardiac sinoatrial nodal cells and regulates pacemaker function
Lukyanenko, Yevgeniya O, Younes, Antoine, Lyashkov, Alexey E, Tarasov, Kirill V, Riordon, Daniel R, Lee, Joonho, Sirenko, Syevda G, Kobrinsky, Evgeny, Ziman, Bruce, Tarasova, Yelena S, Juhaszova, Magdalena, Sollott, Steven J, Graham, David R, Lakatta, Edward G
Published in Journal of molecular and cellular cardiology (2016)
Published in Journal of molecular and cellular cardiology (2016)
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Journal Article
Familial Hypertrophic Cardiomyopathy-Linked Mutant Troponin T Causes Stress-Induced Ventricular Tachycardia and Ca2+-Dependent Action Potential Remodeling
Knollmann, Björn C, Kirchhof, Paulus, Sirenko, Syevda G, Degen, Hubertus, Greene, Anne E, Schober, Tilmann, Mackow, Jessica C, Fabritz, Larissa, Potter, James D, Morad, Martin
Published in Circulation research (07.03.2003)
Published in Circulation research (07.03.2003)
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Synchronization of Stochastic Ca super(2+) Release Units Creates a Rhythmic Ca super(2+) Clock in Cardiac Pacemaker Cells
Maltsev, Anna V, Maltsev, Victor A, Mikheev, Maxim, Maltseva, Larissa A, Sirenko, Syevda G, Lakatta, Edward G, Stern, Michael D
Published in Biophysical journal (19.01.2011)
Published in Biophysical journal (19.01.2011)
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Journal Article