Open ADAMTS13, induced by antibodies, is a biomarker for subclinical immune-mediated thrombotic thrombocytopenic purpura
Roose, Elien, Schelpe, An-Sofie, Tellier, Edwige, Sinkovits, György, Joly, Bérangère S., Dekimpe, Charlotte, Kaplanski, Gilles, Le Besnerais, Maelle, Mancini, Ilaria, Falter, Tanja, Von Auer, Charis, Feys, Hendrik B., Reti, Marienn, Rossmann, Heidi, Vandenbulcke, Aline, Pareyn, Inge, Voorberg, Jan, Greinacher, Andreas, Benhamou, Ygal, Deckmyn, Hans, Fijnheer, Rob, Prohászka, Zoltan, Peyvandi, Flora, Lämmle, Bernhard, Coppo, Paul, De Meyer, Simon F., Veyradier, Agnès, Vanhoorelbeke, Karen
Published in Blood (16.07.2020)
Published in Blood (16.07.2020)
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Journal Article
Complement Overactivation and Consumption Predicts In-Hospital Mortality in SARS-CoV-2 Infection
Sinkovits, György, Mező, Blanka, Réti, Marienn, Müller, Veronika, Iványi, Zsolt, Gál, János, Gopcsa, László, Reményi, Péter, Szathmáry, Beáta, Lakatos, Botond, Szlávik, János, Bobek, Ilona, Prohászka, Zita Z, Förhécz, Zsolt, Csuka, Dorottya, Hurler, Lisa, Kajdácsi, Erika, Cervenak, László, Kiszel, Petra, Masszi, Tamás, Vályi-Nagy, István, Prohászka, Zoltán
Published in Frontiers in immunology (25.03.2021)
Published in Frontiers in immunology (25.03.2021)
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Journal Article
Annual incidence and severity of acute episodes in hereditary thrombotic thrombocytopenic purpura
Tarasco, Erika, Bütikofer, Lukas, Friedman, Kenneth D., George, James N., Hrachovinova, Ingrid, Knöbl, Paul N., Matsumoto, Masanori, von Krogh, Anne Sophie, Aebi-Huber, Isabella, Cermakova, Zuzana, Górska-Kosicka, Magdalena, Jalowiec, Katarzyna A., Largiadèr, Carlo R., Prohászka, Zoltán, Sinkovits, György, Windyga, Jerzy, Lämmle, Bernhard, Kremer Hovinga, Johanna A.
Published in Blood (24.06.2021)
Published in Blood (24.06.2021)
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Journal Article
Evidence, detailed characterization and clinical context of complement activation in acute multisystem inflammatory syndrome in children
Sinkovits, György, Schnur, János, Hurler, Lisa, Kiszel, Petra, Prohászka, Zita Z., Sík, Pál, Kajdácsi, Erika, Cervenak, László, Maráczi, Veronika, Dávid, Máté, Zsigmond, Borbála, Rimanóczy, Éva, Bereczki, Csaba, Willems, Loek, Toonen, Erik J. M., Prohászka, Zoltán
Published in Scientific reports (17.11.2022)
Published in Scientific reports (17.11.2022)
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Journal Article
Anti-Inflammatory Cytokine Profiles in Thrombotic Thrombocytopenic Purpura-Differences Compared to COVID-19
Demeter, Flóra, Bihari, György, Vadicsku, Dorina, Sinkovits, György, Kajdácsi, Erika, Horváth, Laura, Réti, Marienn, Müller, Veronika, Iványi, Zsolt, Gál, János, Gopcsa, László, Reményi, Péter, Szathmáry, Beáta, Lakatos, Botond, Szlávik, János, Bobek, Ilona, Prohászka, Zita Z, Förhécz, Zsolt, Masszi, Tamás, Vályi-Nagy, István, Prohászka, Zoltán, Cervenak, László
Published in International journal of molecular sciences (17.09.2024)
Published in International journal of molecular sciences (17.09.2024)
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Journal Article
Concentration and Subclass Distribution of Anti-ADAMTS13 IgG Autoantibodies in Different Stages of Acquired Idiopathic Thrombotic Thrombocytopenic Purpura
Sinkovits, György, Szilágyi, Ágnes, Farkas, Péter, Inotai, Dóra, Szilvási, Anikó, Tordai, Attila, Rázsó, Katalin, Réti, Marienn, Prohászka, Zoltán
Published in Frontiers in immunology (16.07.2018)
Published in Frontiers in immunology (16.07.2018)
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Journal Article
Immunogenic hotspots in the spacer domain of ADAMTS13 in immune‐mediated thrombotic thrombocytopenic purpura
Velásquez Pereira, Leydi Carolina, Roose, Elien, Graça, Nuno A. G., Sinkovits, György, Kangro, Kadri, Joly, Bérangère S., Tellier, Edwige, Kaplanski, Gilles, Falter, Tanja, Von Auer, Charis, Rossmann, Heidi, Feys, Hendrik B., Reti, Marienn, Prohászka, Zoltán, Lämmle, Bernhard, Voorberg, Jan, Coppo, Paul, Veyradier, Agnès, De Meyer, Simon F., Männik, Andres, Vanhoorelbeke, Karen
Published in Journal of thrombosis and haemostasis (01.02.2021)
Published in Journal of thrombosis and haemostasis (01.02.2021)
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Journal Article
Complement activation, inflammation and relative ADAMTS13 deficiency in secondary thrombotic microangiopathies
Farkas, Péter, Csuka, Dorottya, Mikes, Bálint, Sinkovits, György, Réti, Marienn, Németh, Endre, Rácz, Kristóf, Madách, Krisztina, Gergely, Mihály, Demeter, Judit, Prohászka, Zoltán, MD, DSc
Published in Immunobiology (1979) (01.02.2017)
Published in Immunobiology (1979) (01.02.2017)
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Journal Article
Decreased circulating dipeptidyl peptidase-4 enzyme activity is prognostic for severe outcomes in COVID-19 inpatients
Nádasdi, Ákos, Sinkovits, György, Bobek, Ilona, Lakatos, Botond, Förhécz, Zsolt, Prohászka, Zita Z, Réti, Marienn, Arató, Miklós, Cseh, Gellért, Masszi, Tamás, Merkely, Béla, Ferdinandy, Péter, Vályi-Nagy, István, Prohászka, Zoltán, Firneisz, Gábor
Published in Biomarkers in medicine (01.04.2022)
Published in Biomarkers in medicine (01.04.2022)
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Journal Article
Hemolytic uremic syndrome in the setting of COVID-19 successfully treated with complement inhibition therapy: An instructive case report of a previously healthy toddler and review of literature
Matošević, Matija, Kos, Ivanka, Davidović, Maša, Ban, Maja, Matković, Hana, Jakopčić, Ivan, Vuković Brinar, Ivana, Szilágyi, Ágnes, Csuka, Dorottya, Sinkovits, György, Prohászka, Zoltán, Vrljičak, Kristina, Lamot, Lovro
Published in Frontiers in pediatrics (15.02.2023)
Published in Frontiers in pediatrics (15.02.2023)
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Journal Article
Elevated Systemic Pentraxin-3 Is Associated With Complement Consumption in the Acute Phase of Thrombotic Microangiopathies
Trojnar, Eszter, Józsi, Mihály, Szabó, Zsóka, Réti, Marienn, Farkas, Péter, Kelen, Kata, Reusz, George S, Szabó, Attila J, Garam, Nóra, Mikes, Bálint, Sinkovits, György, Mező, Blanka, Csuka, Dorottya, Prohászka, Zoltán
Published in Frontiers in immunology (25.02.2019)
Published in Frontiers in immunology (25.02.2019)
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Journal Article
Open ADAMTS13 Conformation in Immune-Mediated Thrombotic Thrombocytopenic Purpura Is Induced By Anti-ADAMTS13 Autoantibodies and Corresponds with an Ongoing ADAMTS13 Pathology
Roose, Elien, Schelpe, An-Sofie, Tellier, Edwige, Sinkovits, György, Kaplanski, Gilles, Le Besnerais, Maelle, Mancini, Ilaria, Vandeputte, Nele, Vandenbulcke, Aline, Pareyn, Inge, Voorberg, J.J., Greinacher, Andreas, Benhamou, Ygal, Deckmyn, Hans, FIjnheer, Rob, Prohászka, Zoltan, Peyvandi, Flora, Coppo, Paul, De Meyer, Simon F, Veyradier, Agnès, Vanhoorelbeke, Karen
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Journal Article
Anti-ADAMTS13 autoantibody profiling in patients with immune-mediated thrombotic thrombocytopenic purpura
Kangro, Kadri, Roose, Elien, Joly, Bérangère S., Sinkovits, György, Falter, Tanja, von Auer, Charis, Rossmann, Heidi, Reti, Marienn, Voorberg, Jan, Prohászka, Zoltán, Lämmle, Bernhard, Coppo, Paul, Veyradier, Agnès, De Meyer, Simon F., Männik, Andres, Vanhoorelbeke, Karen
Published in Blood advances (14.09.2021)
Published in Blood advances (14.09.2021)
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Journal Article
Complement Levels at Admission Reflecting Progression to Severe Acute Kidney Injury (AKI) in Coronavirus Disease 2019 (COVID-19): A Multicenter Prospective Cohort Study
Henry, Brandon M, Sinkovits, György, Szergyuk, Ivan, de Oliveira, Maria Helena Santos, Lippi, Giuseppe, Benoit, Justin L, Favaloro, Emmanuel J, Pode-Shakked, Naomi, Benoit, Stefanie W, Cooper, David S, Müller, Veronika, Iványi, Zsolt, Gál, János, Réti, Marienn, Gopcsa, László, Reményi, Péter, Szathmáry, Beáta, Lakatos, Botond, Szlávik, János, Bobek, Ilona, Prohászka, Zita Z, Förhécz, Zsolt, Csuka, Dorottya, Hurler, Lisa, Kajdácsi, Erika, Cervenak, László, Mező, Blanka, Kiszel, Petra, Masszi, Tamás, Vályi-Nagy, István, Prohászka, Zoltán
Published in Frontiers in medicine (29.04.2022)
Published in Frontiers in medicine (29.04.2022)
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Journal Article
Early Increase in Complement Terminal Pathway Activation Marker sC5b-9 Is Predictive for the Development of Thrombotic Microangiopathy after Stem Cell Transplantation
Horváth, Orsolya, Kállay, Krisztián, Csuka, Dorottya, Mező, Blanka, Sinkovits, György, Kassa, Csaba, Stréhn, Anita, Csordás, Katalin, Sinkó, János, Prohászka, Zoltán, Kriván, Gergely
Published in Biology of blood and marrow transplantation (01.05.2018)
Published in Biology of blood and marrow transplantation (01.05.2018)
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Journal Article
Class switch towards spike protein-specific IgG4 antibodies after SARS-CoV-2 mRNA vaccination depends on prior infection history
Kiszel, Petra, Sík, Pál, Miklós, János, Kajdácsi, Erika, Sinkovits, György, Cervenak, László, Prohászka, Zoltán
Published in Scientific reports (13.08.2023)
Published in Scientific reports (13.08.2023)
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Journal Article
Associations between the von Willebrand Factor—ADAMTS13 Axis, Complement Activation, and COVID-19 Severity and Mortality
Sinkovits, György, Réti, Marienn, Müller, Veronika, Iványi, Zsolt, Gál, János, Gopcsa, László, Reményi, Péter, Szathmáry, Beáta, Lakatos, Botond, Szlávik, János, Bobek, Ilona, Prohászka, Zita Z., Förhécz, Zsolt, Mező, Blanka, Csuka, Dorottya, Hurler, Lisa, Kajdácsi, Erika, Cervenak, László, Kiszel, Petra, Masszi, Tamás, Vályi-Nagy, István, Prohászka, Zoltán
Published in Thrombosis and haemostasis (01.02.2022)
Published in Thrombosis and haemostasis (01.02.2022)
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Journal Article
Validation of Early Increase in Complement Activation Marker sC5b-9 as a Predictive Biomarker for the Development of Thrombotic Microangiopathy After Stem Cell Transplantation
Mezö, Blanka, Horváth, Orsolya, Sinkovits, György, Veszeli, Nóra, Kriván, Gergely, Prohászka, Zoltán
Published in Frontiers in medicine (06.10.2020)
Published in Frontiers in medicine (06.10.2020)
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Journal Article
Platelet Count, ADAMTS13 Activity, von Willebrand Factor Level and Survival in Patients with Colorectal Cancer: 5-Year Follow-up Study
Garam, Nóra, Maláti, Éva, Sinkovits, György, Gombos, Tímea, Szederjesi, Attila, Barabás, Loránd, Gráf, László, Kocsis, Judit, Prohászka, Zoltán
Published in Thrombosis and haemostasis (01.01.2018)
Published in Thrombosis and haemostasis (01.01.2018)
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