TREM2 triggers microglial density and age‐related neuronal loss
Linnartz‐Gerlach, Bettina, Bodea, Liviu‐Gabriel, Klaus, Christine, Ginolhac, Aurélien, Halder, Rashi, Sinkkonen, Lasse, Walter, Jochen, Colonna, Marco, Neumann, Harald
Published in Glia (01.03.2019)
Published in Glia (01.03.2019)
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Dicer is associated with ribosomal DNA chromatin in mammalian cells
Sinkkonen, Lasse, Hugenschmidt, Tabea, Filipowicz, Witold, Svoboda, Petr
Published in PloS one (13.08.2010)
Published in PloS one (13.08.2010)
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Focal adhesion kinase plays a dual role in TRAIL resistance and metastatic outgrowth of malignant melanoma
Del Mistro, Greta, Riemann, Shamala, Schindler, Sebastian, Beissert, Stefan, Kontermann, Roland E, Ginolhac, Aurelien, Halder, Rashi, Presta, Luana, Sinkkonen, Lasse, Sauter, Thomas, Kulms, Dagmar
Published in Cell death & disease (12.01.2022)
Published in Cell death & disease (12.01.2022)
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MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells
Svoboda, Petr, Filipowicz, Witold, Sinkkonen, Lasse, Hugenschmidt, Tabea, Berninger, Philipp, Gaidatzis, Dimos, Mohn, Fabio, Artus-Revel, Caroline G, Zavolan, Mihaela
Published in Nature structural & molecular biology (01.03.2008)
Published in Nature structural & molecular biology (01.03.2008)
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Stress-induced inflammation evoked by immunogenic cell death is blunted by the IRE1α kinase inhibitor KIRA6 through HSP60 targeting
Rufo, Nicole, Korovesis, Dimitris, Van Eygen, Sofie, Derua, Rita, Garg, Abhishek D, Finotello, Francesca, Vara-Perez, Monica, Rožanc, Jan, Dewaele, Michael, de Witte, Peter A, Alexopoulos, Leonidas G, Janssens, Sophie, Sinkkonen, Lasse, Sauter, Thomas, Verhelst, Steven H L, Agostinis, Patrizia
Published in Cell death and differentiation (01.01.2022)
Published in Cell death and differentiation (01.01.2022)
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Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions
Soriano-Baguet, Leticia, Grusdat, Melanie, Kurniawan, Henry, Benzarti, Mohaned, Binsfeld, Carole, Ewen, Anouk, Longworth, Joseph, Bonetti, Lynn, Guerra, Luana, Franchina, Davide G., Kobayashi, Takumi, Horkova, Veronika, Verschueren, Charlène, Helgueta, Sergio, Gérard, Deborah, More, Tushar H., Henne, Antonia, Dostert, Catherine, Farinelle, Sophie, Lesur, Antoine, Gérardy, Jean-Jacques, Jäger, Christian, Mittelbronn, Michel, Sinkkonen, Lasse, Hiller, Karsten, Meiser, Johannes, Brenner, Dirk
Published in Cell reports (Cambridge) (28.03.2023)
Published in Cell reports (Cambridge) (28.03.2023)
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Normal and Pathological NRF2 Signalling in the Central Nervous System
Heurtaux, Tony, Bouvier, David S, Benani, Alexandre, Helgueta Romero, Sergio, Frauenknecht, Katrin B. M, Mittelbronn, Michel, Sinkkonen, Lasse
Published in Antioxidants (22.07.2022)
Published in Antioxidants (22.07.2022)
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Web Resource
The Parkinson’s-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1
Walter, Jonas, Bolognin, Silvia, Poovathingal, Suresh K., Magni, Stefano, Gérard, Deborah, Antony, Paul M.A., Nickels, Sarah L., Salamanca, Luis, Berger, Emanuel, Smits, Lisa M., Grzyb, Kamil, Perfeito, Rita, Hoel, Fredrik, Qing, Xiaobing, Ohnmacht, Jochen, Bertacchi, Michele, Jarazo, Javier, Ignac, Tomasz, Monzel, Anna S., Gonzalez-Cano, Laura, Krüger, Rejko, Sauter, Thomas, Studer, Michèle, de Almeida, Luis Pereira, Tronstad, Karl J., Sinkkonen, Lasse, Skupin, Alexander, Schwamborn, Jens C.
Published in Cell reports (Cambridge) (19.10.2021)
Published in Cell reports (Cambridge) (19.10.2021)
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Metabolic modelling-based in silico drug target prediction identifies six novel repurposable drugs for melanoma
Bintener, Tamara, Pacheco, Maria Pires, Philippidou, Demetra, Margue, Christiane, Kishk, Ali, Del Mistro, Greta, Di Leo, Luca, Moscardó Garcia, Maria, Halder, Rashi, Sinkkonen, Lasse, De Zio, Daniela, Kreis, Stephanie, Kulms, Dagmar, Sauter, Thomas
Published in Cell death & disease (26.07.2023)
Published in Cell death & disease (26.07.2023)
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ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1
Frangež, Živa, Gérard, Deborah, He, Zhaoyue, Gavriil, Marios, Fernández-Marrero, Yuniel, Seyed Jafari, S. Morteza, Hunger, Robert E., Lucarelli, Philippe, Yousefi, Shida, Sauter, Thomas, Sinkkonen, Lasse, Simon, Hans-Uwe
Published in Frontiers in oncology (12.08.2021)
Published in Frontiers in oncology (12.08.2021)
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Nanopore Single-Molecule Sequencing for Mitochondrial DNA Methylation Analysis: Investigating Parkin-Associated Parkinsonism as a Proof of Concept
Lüth, Theresa, Wasner, Kobi, Klein, Christine, Schaake, Susen, Tse, Ronnie, Pereira, Sandro L, Laß, Joshua, Sinkkonen, Lasse, Grünewald, Anne, Trinh, Joanne
Published in Frontiers in aging neuroscience (28.09.2021)
Published in Frontiers in aging neuroscience (28.09.2021)
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Review of Current Human Genome-Scale Metabolic Models for Brain Cancer and Neurodegenerative Diseases
Kishk, Ali, Pacheco, Maria Pires, Heurtaux, Tony, Sinkkonen, Lasse, Pang, Jun, Fritah, Sabrina, Niclou, Simone P, Sauter, Thomas
Published in Cells (Basel, Switzerland) (01.08.2022)
Published in Cells (Basel, Switzerland) (01.08.2022)
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Single-nuclei chromatin profiling of ventral midbrain reveals cell identity transcription factors and cell-type-specific gene regulatory variation
Gui, Yujuan, Grzyb, Kamil, Thomas, Mélanie H, Ohnmacht, Jochen, Garcia, Pierre, Buttini, Manuel, Skupin, Alexander, Sauter, Thomas, Sinkkonen, Lasse
Published in Epigenetics & chromatin (09.09.2021)
Published in Epigenetics & chromatin (09.09.2021)
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Pituitary Tumor Transforming Gene 1 Orchestrates Gene Regulatory Variation in Mouse Ventral Midbrain During Aging
Gui, Yujuan, Thomas, Mélanie H., Garcia, Pierre, Karout, Mona, Halder, Rashi, Michelucci, Alessandro, Kollmus, Heike, Zhou, Cuiqi, Melmed, Shlomo, Schughart, Klaus, Balling, Rudi, Mittelbronn, Michel, Nadeau, Joseph H., Williams, Robert W., Sauter, Thomas, Buttini, Manuel, Sinkkonen, Lasse
Published in Frontiers in genetics (23.09.2020)
Published in Frontiers in genetics (23.09.2020)
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Time-resolved expression profiling of the nuclear receptor superfamily in human adipogenesis
Lahnalampi, Mari, Heinäniemi, Merja, Sinkkonen, Lasse, Wabitsch, Martin, Carlberg, Carsten
Published in PloS one (27.09.2010)
Published in PloS one (27.09.2010)
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Transcriptomics profiling of human SGBS adipogenesis
Galhardo, Mafalda, Sinkkonen, Lasse, Berninger, Philipp, Lin, Jake, Sauter, Thomas, Heinäniemi, Merja
Published in Genomics data (01.12.2014)
Published in Genomics data (01.12.2014)
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Missing heritability in Parkinson’s disease: the emerging role of non-coding genetic variation
Ohnmacht, Jochen, May, Patrick, Sinkkonen, Lasse, Krüger, Rejko
Published in Journal of Neural Transmission (01.05.2020)
Published in Journal of Neural Transmission (01.05.2020)
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Phagocytosis‐related NADPH oxidase 2 subunit gp91phox contributes to neurodegeneration after repeated systemic challenge with lipopolysaccharides
Shahraz, Anahita, Wißfeld, Jannis, Ginolhac, Aurélien, Mathews, Mona, Sinkkonen, Lasse, Neumann, Harald
Published in Glia (01.01.2021)
Published in Glia (01.01.2021)
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Integrated analysis of transcript-level regulation of metabolism reveals disease-relevant nodes of the human metabolic network
Galhardo, Mafalda, Sinkkonen, Lasse, Berninger, Philipp, Lin, Jake, Sauter, Thomas, Heinäniemi, Merja
Published in Nucleic acids research (01.02.2014)
Published in Nucleic acids research (01.02.2014)
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