GLIPR2 is a negative regulator of autophagy and the BECN1-ATG14-containing phosphatidylinositol 3-kinase complex
Zhao, Yuting, Zou, Zhongju, Sun, Daxiao, Li, Yue, Sinha, Sangita C., Yu, Li, Bennett, Lynda, Levine, Beth
Published in Autophagy (03.10.2021)
Published in Autophagy (03.10.2021)
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Journal Article
Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2
Saito, Takeshi, Hirai, Reiko, Loo, Yueh-Ming, Owen, David, Johnson, Cynthia L, Sinha, Sangita C, Akira, Shizuo, Fujita, Takashi, Gale, Michael Jr
Published in Proceedings of the National Academy of Sciences - PNAS (09.01.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (09.01.2007)
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Journal Article
Intrinsically disordered regions in autophagy proteins
Mei, Yang, Su, Minfei, Soni, Gaurav, Salem, Saeed, Colbert, Christopher L., Sinha, Sangita C.
Published in Proteins, structure, function, and bioinformatics (01.04.2014)
Published in Proteins, structure, function, and bioinformatics (01.04.2014)
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Journal Article
Structural characterization of Pandoraea pnomenusa B-356 biphenyl dioxygenase reveals features of potent polychlorinated biphenyl-degrading enzymes
Colbert, Christopher L, Agar, Nathalie Y R, Kumar, Pravindra, Chakko, Mathew N, Sinha, Sangita C, Powlowski, Justin B, Eltis, Lindsay D, Bolin, Jeffrey T
Published in PloS one (03.01.2013)
Published in PloS one (03.01.2013)
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Journal Article
Origin of asymmetry in adenylyl cyclases: structures of Mycobacterium tuberculosis Rv1900c
Sinha, Sangita C, Wetterer, Martina, Sprang, Stephen R, Schultz, Joachim E, Linder, Jürgen U
Published in The EMBO journal (23.02.2005)
Published in The EMBO journal (23.02.2005)
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Journal Article
Invariant BECN1 CXXC motifs bind Zn2+ and regulate structure and function of the BECN1 intrinsically disordered region
Mukhopadhyay, Shreya, Subedi, Subeksha, Hopkins, Jesse B., Ugrinov, Angel, Chakravarthy, Srinivas, Colbert, Christopher L., Sinha, Sangita C.
Published in Autophagy (01.02.2024)
Published in Autophagy (01.02.2024)
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Journal Article
Invariant BECN1 CXXC motifs bind Zn 2+ and regulate structure and function of the BECN1 intrinsically disordered region
Mukhopadhyay, Shreya, Subedi, Subeksha, Hopkins, Jesse B, Ugrinov, Angel, Chakravarthy, Srinivas, Colbert, Christopher L, Sinha, Sangita C
Published in Autophagy (01.02.2024)
Published in Autophagy (01.02.2024)
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Journal Article
Epstein–Barr Virus Encoded BCL2, BHRF1, Downregulates Autophagy by Noncanonical Binding of BECN1
Wyatt, Samuel, Glover, Karen, Dasanna, Srinivasulu, Lewison, Monica, González-García, Maribel, Colbert, Christopher L., Sinha, Sangita C.
Published in Biochemistry (Easton) (17.10.2023)
Published in Biochemistry (Easton) (17.10.2023)
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Journal Article
Identification of BECN1 and ATG14 Coiled-Coil Interface Residues That Are Important for Starvation-Induced Autophagy
Mei, Yang, Su, Minfei, Sanishvili, Ruslan, Chakravarthy, Srinivas, Colbert, Christopher L, Sinha, Sangita C
Published in Biochemistry (Easton) (02.08.2016)
Published in Biochemistry (Easton) (02.08.2016)
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Journal Article
Structural transitions in conserved, ordered Beclin 1 domains essential to regulating autophagy
Glover, Karen, Li, Yue, Mukhopadhyay, Shreya, Leuthner, Zoe, Chakravarthy, Srinivas, Colbert, Christopher L., Sinha, Sangita C.
Published in The Journal of biological chemistry (29.09.2017)
Published in The Journal of biological chemistry (29.09.2017)
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Journal Article
Conformational Flexibility Enables the Function of a BECN1 Region Essential for Starvation-Mediated Autophagy
Mei, Yang, Ramanathan, Arvind, Glover, Karen, Stanley, Christopher, Sanishvili, Ruslan, Chakravarthy, Srinivas, Yang, Zhongyu, Colbert, Christopher L, Sinha, Sangita C
Published in Biochemistry (Easton) (05.04.2016)
Published in Biochemistry (Easton) (05.04.2016)
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Journal Article
Structural insights into the interaction of the conserved mammalian proteins GAPR-1 and Beclin 1, a key autophagy protein
Li, Yue, Zhao, Yuting, Su, Minfei, Glover, Karen, Chakravarthy, Srinivas, Colbert, Christopher L, Levine, Beth, Sinha, Sangita C
Published in Acta crystallographica. Section D, Biological crystallography. (01.09.2017)
Published in Acta crystallographica. Section D, Biological crystallography. (01.09.2017)
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Journal Article
Molecular basis of the regulation of Beclin 1-dependent autophagy by the γ-herpesvirus 68 Bcl-2 homolog M11
Sinha, Sangita C., Colbert, Christopher L., Becker, Nils, Wei, Yongjie, Levine, Beth
Published in Autophagy (16.11.2008)
Published in Autophagy (16.11.2008)
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Journal Article
BECN2 interacts with ATG14 through a metastable coiled‐coil to mediate autophagy
Su, Minfei, Li, Yue, Wyborny, Shane, Neau, David, Chakravarthy, Srinivas, Levine, Beth, Colbert, Christopher L., Sinha, Sangita C.
Published in Protein science (01.05.2017)
Published in Protein science (01.05.2017)
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