Search Results - "Simone GREVEN" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Preclinical Efficacy of the Auristatin-Based Antibody-Drug Conjugate BAY 1187982 for the Treatment of FGFR2-Positive Solid Tumors

Preclinical Efficacy of the Auristatin-Based Antibody-Drug Conjugate BAY 1187982 for the Treatment of FGFR2-Positive Solid Tumors

by Sommer, Anette, Kopitz, Charlotte, Schatz, Christoph A, Nising, Carl F, Mahlert, Christoph, Lerchen, Hans-Georg, Stelte-Ludwig, Beatrix, Hammer, Stefanie, Greven, Simone, Schuhmacher, Joachim, Braun, Manuela, Zierz, Ruprecht, Wittemer-Rump, Sabine, Harrenga, Axel, Dittmer, Frank, Reetz, Frank, Apeler, Heiner, Jautelat, Rolf, Huynh, Hung, Ziegelbauer, Karl, Kreft, Bertolt
Published in Cancer research (Chicago, Ill.) (01.11.2016)

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IL3RA-Targeting Antibody–Drug Conjugate BAY-943 with a Kinesin Spindle Protein Inhibitor Payload Shows Efficacy in Preclinical Models of Hematologic Malignancies

IL3RA-Targeting Antibody–Drug Conjugate BAY-943 with a Kinesin Spindle Protein Inhibitor Payload Shows Efficacy in Preclinical Models of Hematologic Malignancies

by Kirchhoff, Dennis, Stelte-Ludwig, Beatrix, Lerchen, Hans-Georg, Wengner, Antje Margret, Ahsen, Oliver von, Buchmann, Pascale, Märsch, Stephan, Mahlert, Christoph, Greven, Simone, Dietz, Lisa, Erkelenz, Michael, Zierz, Ruprecht, Johanssen, Sandra, Mumberg, Dominik, Sommer, Anette
Published in Cancers (01.11.2020)

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Site-specific modification of ED-B-targeting antibody using intein-fusion technology

Site-specific modification of ED-B-targeting antibody using intein-fusion technology

by Möhlmann, Sina, Bringmann, Peter, Greven, Simone, Harrenga, Axel
Published in BMC biotechnology (21.07.2011)

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A study on the trastuzumab conjugation at tyrosine using diazonium salts

A study on the trastuzumab conjugation at tyrosine using diazonium salts

by Griebenow, Nils, Greven, Simone, Lobell, Mario, Dilmaç, Alicia M, Bräse, Stefan
Published in RSC advances (01.01.2015)

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Tailored Linker Chemistries for the Efficient and Selective Activation of ADCs with KSPi Payloads

Tailored Linker Chemistries for the Efficient and Selective Activation of ADCs with KSPi Payloads

by Lerchen, Hans-Georg, Stelte-Ludwig, Beatrix, Sommer, Anette, Berndt, Sandra, Rebstock, Anne-Sophie, Johannes, Sarah, Mahlert, Christoph, Greven, Simone, Dietz, Lisa, Jörißen, Hannah
Published in Bioconjugate chemistry (19.08.2020)

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A Novel NAMPT Inhibitor-Based Antibody–Drug Conjugate Payload Class for Cancer Therapy

A Novel NAMPT Inhibitor-Based Antibody–Drug Conjugate Payload Class for Cancer Therapy

by Böhnke, Niels, Berger, Markus, Griebenow, Nils, Rottmann, Antje, Erkelenz, Michael, Hammer, Stefanie, Berndt, Sandra, Günther, Judith, Wengner, Antje M., Stelte-Ludwig, Beatrix, Mahlert, Christoph, Greven, Simone, Dietz, Lisa, Jörißen, Hannah, Barak, Naomi, Bömer, Ulf, Hillig, Roman C., Eberspaecher, Uwe, Weiske, Jörg, Giese, Anja, Mumberg, Dominik, Nising, Carl Friedrich, Weinmann, Hilmar, Sommer, Anette
Published in Bioconjugate chemistry (15.06.2022)

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Technical considerations for the implementation of the multi-attribute-method by mass spectrometry in a quality control laboratory

Technical considerations for the implementation of the multi-attribute-method by mass spectrometry in a quality control laboratory

by Pohl, Thomas, Gervais, Annick, Dirksen, Eef H.C., D'Alessio, Valerio, Bechtold-Peters, Karoline, Burkitt, Will, Cao, Li, Greven, Simone, Lennard, Andrew, Li, Xue, Lössner, Christopher, Niu, Ben, Reusch, Dietmar, O'Riordan, Tomás, Shearer, Justin W., Spencer, David, Xu, Wei, Yi, Linda
Published in European journal of pharmaceutics and biopharmaceutics (01.07.2023)

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Compliance and regulatory considerations for the implementation of the multi-attribute-method by mass spectrometry in a quality control laboratory

Compliance and regulatory considerations for the implementation of the multi-attribute-method by mass spectrometry in a quality control laboratory

by Gervais, Annick, Dirksen, Eef H.C., Pohl, Thomas, Bechtold-Peters, Karoline, Burkitt, Will, D'Alessio, Valerio, Greven, Simone, Lennard, Andrew, Li, Xue, Lössner, Christopher, Niu, Ben, Reusch, Dietmar, O'Riordan, Tomás, Shearer, Justin W., Spencer, David, Xu, Wei, Yi, Linda
Published in European journal of pharmaceutics and biopharmaceutics (01.10.2023)

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Site-Specific Conjugation of Peptides and Proteins via Rebridging of Disulfide Bonds Using the Thiol–Yne Coupling Reaction

Site-Specific Conjugation of Peptides and Proteins via Rebridging of Disulfide Bonds Using the Thiol–Yne Coupling Reaction

by Griebenow, Nils, Dilmaç, Alicia M, Greven, Simone, Bräse, Stefan
Published in Bioconjugate chemistry (20.04.2016)

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Antibody–Drug Conjugates with Pyrrole‐Based KSP Inhibitors as the Payload Class

Antibody–Drug Conjugates with Pyrrole‐Based KSP Inhibitors as the Payload Class

by Lerchen, Hans‐Georg, Wittrock, Sven, Stelte‐Ludwig, Beatrix, Sommer, Anette, Berndt, Sandra, Griebenow, Nils, Rebstock, Anne‐Sophie, Johannes, Sarah, Cancho‐Grande, Yolanda, Mahlert, Christoph, Greven, Simone, Terjung, Carsten
Published in Angewandte Chemie International Edition (12.11.2018)

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Abstract 4825: Preclinical characterization of BAY-924, a first in class ADC targeting CXCR5-positive B-cell malignancies, with a KSP inhibitor as novel payload

Abstract 4825: Preclinical characterization of BAY-924, a first in class ADC targeting CXCR5-positive B-cell malignancies, with a KSP inhibitor as novel payload

by Johannes, Sarah, Hammer, Stefanie, Maersch, Stephan, Lerchen, Hans-Georg, Stelte-Ludwig, Beatrix, Joerissen, Hannah, Ahsen, Oliver von, Schatz, Christoph, Greven, Simone, Mahlert, Christoph, Mumberg, Dominik, Lejeune, Pascale
Published in Cancer research (Chicago, Ill.) (01.07.2019)

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Abstract 228: KSPi-ADCs: ADCs with novel kinesin spindle protein inhibitor payloads and a tailor-made linker chemistry

Abstract 228: KSPi-ADCs: ADCs with novel kinesin spindle protein inhibitor payloads and a tailor-made linker chemistry

by Lerchen, Hans-Georg, Stelte-Ludwig, Beatrix, Sommer, Anette, Berndt, Sandra, Rebstock, Anne-Sophie, Johannes, Sarah, Marx, Leo, Mahlert, Christoph, Greven, Simone, Dietz, Lisa, Joerissen, Hannah, Weinmann, Hilmar
Published in Cancer research (Chicago, Ill.) (01.07.2019)

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Front Cover: Antibody–Prodrug Conjugates with KSP Inhibitors and Legumain‐Mediated Metabolite Formation (Chem. Eur. J. 35/2019)

Front Cover: Antibody–Prodrug Conjugates with KSP Inhibitors and Legumain‐Mediated Metabolite Formation (Chem. Eur. J. 35/2019)

by Lerchen, Hans‐Georg, Stelte‐Ludwig, Beatrix, Berndt, Sandra, Sommer, Anette, Dietz, Lisa, Rebstock, Anne‐Sophie, Johannes, Sarah, Marx, Leo, Jörißen, Hannah, Mahlert, Christoph, Greven, Simone
Published in Chemistry : a European journal (21.06.2019)

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In vitro Sortagging of an Antibody Fab Fragment: Overcoming Unproductive Reactions of Sortase with Water and Lysine Side Chains

In vitro Sortagging of an Antibody Fab Fragment: Overcoming Unproductive Reactions of Sortase with Water and Lysine Side Chains

by Möhlmann, Sina, Mahlert, Christoph, Greven, Simone, Scholz, Peter, Harrenga, Axel
Published in Chembiochem : a European journal of chemical biology (25.07.2011)

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Antibody–Prodrug Conjugates with KSP Inhibitors and Legumain‐Mediated Metabolite Formation

Antibody–Prodrug Conjugates with KSP Inhibitors and Legumain‐Mediated Metabolite Formation

by Lerchen, Hans‐Georg, Stelte‐Ludwig, Beatrix, Berndt, Sandra, Sommer, Anette, Dietz, Lisa, Rebstock, Anne‐Sophie, Johannes, Sarah, Marx, Leo, Jörißen, Hannah, Mahlert, Christoph, Greven, Simone
Published in Chemistry : a European journal (21.06.2019)

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Inside Cover: Antibody–Drug Conjugates with Pyrrole‐Based KSP Inhibitors as the Payload Class (Angew. Chem. Int. Ed. 46/2018)

Inside Cover: Antibody–Drug Conjugates with Pyrrole‐Based KSP Inhibitors as the Payload Class (Angew. Chem. Int. Ed. 46/2018)

by Lerchen, Hans‐Georg, Wittrock, Sven, Stelte‐Ludwig, Beatrix, Sommer, Anette, Berndt, Sandra, Griebenow, Nils, Rebstock, Anne‐Sophie, Johannes, Sarah, Cancho‐Grande, Yolanda, Mahlert, Christoph, Greven, Simone, Terjung, Carsten
Published in Angewandte Chemie International Edition (12.11.2018)

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Abstract 2907: Identification and optimization of a novel NAMPT inhibitor-based ADC payload class for cancer therapy

Abstract 2907: Identification and optimization of a novel NAMPT inhibitor-based ADC payload class for cancer therapy

by Böhnke, Niels, Berger, Markus, Griebenow, Nils, Giese, Anja, Günther, Judith, Sommer, Anette, Hammer, Stefanie, Berndt, Sandra, Wengner, Antje M., Beier, Rudolf, Stelte-Ludwig, Beatrix, Mahlert, Christoph, Greven, Simone, Dietz, Lisa, Joerissen, Hannah, Rottmann, Antje, Erkelenz, Michael, Barak, Naomi, Bömer, Ulf, Mumber, Dominik, Kreft, Bertolt, Linden, Lars, Nising, Carl Friedrich, Weinmann, Hilmar
Published in Cancer research (Chicago, Ill.) (15.08.2020)

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Abstract 1807: Anti-tumor activity of a novel structural class of NAMPT inhibitor-based ADCs in models of hematologic and solid tumor indications

Abstract 1807: Anti-tumor activity of a novel structural class of NAMPT inhibitor-based ADCs in models of hematologic and solid tumor indications

by Sommer, Anette, Hammer, Stefanie, Berndt, Sandra, Wengner, Antje M., Boehnke, Niels, Berger, Markus, Griebenow, Nils, Steffen, Andreas, Stelte-Ludwig, Beatrix, Mahlert, Christoph, Greven, Simone, Dietz, Lisa, Joerissen, Hannah, Giese, Anja, Quanz, Maria, Bao, Zhengzheng, Wu, Xiuli, Weinmann, Hilmar, Linden, Lars, Kreft, Bertolt, Mumberg, Dominik
Published in Cancer research (Chicago, Ill.) (15.08.2020)

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Antibody–Prodrug Conjugates with KSP Inhibitors and Legumain‐Mediated Metabolite Formation

Antibody–Prodrug Conjugates with KSP Inhibitors and Legumain‐Mediated Metabolite Formation

by Lerchen, Hans‐Georg, Stelte‐Ludwig, Beatrix, Berndt, Sandra, Sommer, Anette, Dietz, Lisa, Rebstock, Anne‐Sophie, Johannes, Sarah, Marx, Leo, Jörißen, Hannah, Mahlert, Christoph, Greven, Simone
Published in Chemistry : a European journal (21.06.2019)

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Abstract 3234: Development of potent and selective antibody-drug conjugates with pyrrole-based KSP inhibitors as novel payload class

Abstract 3234: Development of potent and selective antibody-drug conjugates with pyrrole-based KSP inhibitors as novel payload class

by Lerchen, Hans-Georg, Wittrock, Sven, Griebenow, Nils, Lobell, Mario, Rebstock, Anne-Sophie, Cancho-Grande, Yolanda, Stelte-Ludwig, Beatrix, Mahlert, Christoph, Greven, Simone, Sommer, Anette, Berndt, Sandra, Terjung, Carsten, Apeler, Heiner, Kreft, Bertolt, Jautelat, Rolf
Published in Cancer research (Chicago, Ill.) (01.07.2017)

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