Single-cell analysis of human adipose tissue identifies depot and disease specific cell types
Vijay, Jinchu, Gauthier, Marie-Frédérique, Biswell, Rebecca L, Louiselle, Daniel A, Johnston, Jeffrey J, Cheung, Warren A, Belden, Bradley, Pramatarova, Albena, Biertho, Laurent, Gibson, Margaret, Simon, Marie-Michelle, Djambazian, Haig, Staffa, Alfredo, Bourque, Guillaume, Laitinen, Anita, Nystedt, Johanna, Vohl, Marie-Claude, Fraser, Jason D, Pastinen, Tomi, Tchernof, André, Grundberg, Elin
Published in Nature metabolism (01.01.2020)
Published in Nature metabolism (01.01.2020)
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Integrative analysis of vascular endothelial cell genomic features identifies AIDA as a coronary artery disease candidate gene
Lalonde, Simon, Codina-Fauteux, Valérie-Anne, de Bellefon, Sébastian Méric, Leblanc, Francis, Beaudoin, Mélissa, Simon, Marie-Michelle, Dali, Rola, Kwan, Tony, Lo, Ken Sin, Pastinen, Tomi, Lettre, Guillaume
Published in Genome Biology (08.07.2019)
Published in Genome Biology (08.07.2019)
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Population whole-genome bisulfite sequencing across two tissues highlights the environment as the principal source of human methylome variation
Busche, Stephan, Shao, Xiaojian, Caron, Maxime, Kwan, Tony, Allum, Fiona, Cheung, Warren A, Ge, Bing, Westfall, Susan, Simon, Marie-Michelle, Barrett, Amy, Bell, Jordana T, McCarthy, Mark I, Deloukas, Panos, Blanchette, Mathieu, Bourque, Guillaume, Spector, Timothy D, Lathrop, Mark, Pastinen, Tomi, Grundberg, Elin
Published in Genome Biology (23.12.2015)
Published in Genome Biology (23.12.2015)
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Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome
Cheung, Warren A, Shao, Xiaojian, Morin, Andréanne, Siroux, Valérie, Kwan, Tony, Ge, Bing, Aïssi, Dylan, Chen, Lu, Vasquez, Louella, Allum, Fiona, Guénard, Frédéric, Bouzigon, Emmanuelle, Simon, Marie-Michelle, Boulier, Elodie, Redensek, Adriana, Watt, Stephen, Datta, Avik, Clarke, Laura, Flicek, Paul, Mead, Daniel, Paul, Dirk S, Beck, Stephan, Bourque, Guillaume, Lathrop, Mark, Tchernof, André, Vohl, Marie-Claude, Demenais, Florence, Pin, Isabelle, Downes, Kate, Stunnenberg, Hendrick G, Soranzo, Nicole, Pastinen, Tomi, Grundberg, Elin
Published in Genome Biology (10.03.2017)
Published in Genome Biology (10.03.2017)
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Customized MethylC-Capture Sequencing to Evaluate Variation in the Human Sperm DNA Methylome Representative of Altered Folate Metabolism
Chan, Donovan, Shao, Xiaojian, Dumargne, Marie-Charlotte, Aarabi, Mahmoud, Simon, Marie-Michelle, Kwan, Tony, Bailey, Janice L, Robaire, Bernard, Kimmins, Sarah, San Gabriel, Maria C, Zini, Armand, Librach, Clifford, Moskovtsev, Sergey, Grundberg, Elin, Bourque, Guillaume, Pastinen, Tomi, Trasler, Jacquetta M
Published in Environmental health perspectives (01.08.2019)
Published in Environmental health perspectives (01.08.2019)
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Eosinophil microRNAs Play a Regulatory Role in Allergic Diseases Included in the Atopic March
Bélanger, Émile, Madore, Anne-Marie, Boucher-Lafleur, Anne-Marie, Simon, Marie-Michelle, Kwan, Tony, Pastinen, Tomi, Laprise, Catherine
Published in International journal of molecular sciences (27.11.2020)
Published in International journal of molecular sciences (27.11.2020)
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Capturing sex-specific and hypofertility-linked effects of assisted reproductive technologies on the cord blood DNA methylome
Rahimi, Sophia, Shao, Xiaojian, Chan, Donovan, Martel, Josée, Bérard, Anick, Fraser, William D, Simon, Marie-Michelle, Kwan, Tony, Bourque, Guillaume, Trasler, Jacquetta
Published in Clinical epigenetics (11.05.2023)
Published in Clinical epigenetics (11.05.2023)
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Dissecting features of epigenetic variants underlying cardiometabolic risk using full-resolution epigenome profiling in regulatory elements
Allum, Fiona, Hedman, Åsa K, Shao, Xiaojian, Cheung, Warren A, Vijay, Jinchu, Guénard, Frédéric, Kwan, Tony, Simon, Marie-Michelle, Ge, Bing, Moura, Cristiano, Boulier, Elodie, Rönnblom, Lars, Bernatsky, Sasha, Lathrop, Mark, McCarthy, Mark I, Deloukas, Panos, Tchernof, André, Pastinen, Tomi, Vohl, Marie-Claude, Grundberg, Elin
Published in Nature communications (14.03.2019)
Published in Nature communications (14.03.2019)
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Transposable elements are associated with the variable response to influenza infection
Chen, Xun, Pacis, Alain, Aracena, Katherine A., Gona, Saideep, Kwan, Tony, Groza, Cristian, Lin, Yen Lung, Sindeaux, Renata, Yotova, Vania, Pramatarova, Albena, Simon, Marie-Michelle, Pastinen, Tomi, Barreiro, Luis B., Bourque, Guillaume
Published in Cell genomics (10.05.2023)
Published in Cell genomics (10.05.2023)
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Correction to: Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome
Cheung, Warren A, Shao, Xiaojian, Morin, Andréanne, Siroux, Valérie, Kwan, Tony, Ge, Bing, Aïssi, Dylan, Chen, Lu, Vasquez, Louella, Allum, Fiona, Guénard, Frédéric, Bouzigon, Emmanuelle, Simon, Marie-Michelle, Boulier, Elodie, Redensek, Adriana, Watt, Stephen, Datta, Avik, Clarke, Laura, Flicek, Paul, Mead, Daniel, Paul, Dirk S, Beck, Stephan, Bourque, Guillaume, Lathrop, Mark, Tchernof, André, Vohl, Marie-Claude, Demenais, Florence, Pin, Isabelle, Downes, Kate, Stunnenberg, Hendrick G, Soranzo, Nicole, Pastinen, Tomi, Grundberg, Elin
Published in Genome Biology (07.05.2019)
Published in Genome Biology (07.05.2019)
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Large-scale analysis of circulating glutamate and adipose gene expression in relation to abdominal obesity
Maltais-Payette, Ina, Vijay, Jinchu, Simon, Marie-Michelle, Corbeil, Jacques, Brière, Francis, Grundberg, Elin, Tchernof, André
Published in Amino acids (01.09.2022)
Published in Amino acids (01.09.2022)
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Epigenetic variation impacts individual differences in the transcriptional response to influenza infection
Aracena, Katherine A, Lin, Yen-Lung, Luo, Kaixuan, Pacis, Alain, Gona, Saideep, Mu, Zepeng, Yotova, Vania, Sindeaux, Renata, Pramatarova, Albena, Simon, Marie-Michelle, Chen, Xun, Groza, Cristian, Lougheed, David, Gregoire, Romain, Brownlee, David, Boye, Carly, Pique-Regi, Roger, Li, Yang, He, Xin, Bujold, David, Pastinen, Tomi, Bourque, Guillaume, Barreiro, Luis B
Published in Nature genetics (01.03.2024)
Published in Nature genetics (01.03.2024)
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Increased DNA methylation variability in type 1 diabetes across three immune effector cell types
Paul, Dirk S, Teschendorff, Andrew E, Dang, Mary A N, Lowe, Robert, Hawa, Mohammed I, Ecker, Simone, Beyan, Huriya, Cunningham, Stephanie, Fouts, Alexandra R, Ramelius, Anita, Burden, Frances, Farrow, Samantha, Rowlston, Sophia, Rehnstrom, Karola, Frontini, Mattia, Downes, Kate, Busche, Stephan, Cheung, Warren A, Ge, Bing, Simon, Marie-Michelle, Bujold, David, Kwan, Tony, Bourque, Guillaume, Datta, Avik, Lowy, Ernesto, Clarke, Laura, Flicek, Paul, Libertini, Emanuele, Heath, Simon, Gut, Marta, Gut, Ivo G, Ouwehand, Willem H, Pastinen, Tomi, Soranzo, Nicole, Hofer, Sabine E, Karges, Beate, Meissner, Thomas, Boehm, Bernhard O, Cilio, Corrado, Elding Larsson, Helena, Lernmark, Åke, Steck, Andrea K, Rakyan, Vardhman K, Beck, Stephan, Leslie, R David
Published in Nature communications (29.11.2016)
Published in Nature communications (29.11.2016)
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Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants
Allum, Fiona, Shao, Xiaojian, Guénard, Frédéric, Simon, Marie-Michelle, Busche, Stephan, Caron, Maxime, Lambourne, John, Lessard, Julie, Tandre, Karolina, Hedman, Åsa K, Kwan, Tony, Ge, Bing, Rönnblom, Lars, McCarthy, Mark I, Deloukas, Panos, Richmond, Todd, Burgess, Daniel, Spector, Timothy D, Tchernof, André, Marceau, Simon, Lathrop, Mark, Vohl, Marie-Claude, Pastinen, Tomi, Grundberg, Elin
Published in Nature communications (29.05.2015)
Published in Nature communications (29.05.2015)
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Genome graphs detect human polymorphisms in active epigenomic state during influenza infection
Groza, Cristian, Chen, Xun, Pacis, Alain, Simon, Marie-Michelle, Pramatarova, Albena, Aracena, Katherine A., Pastinen, Tomi, Barreiro, Luis B., Bourque, Guillaume
Published in Cell genomics (10.05.2023)
Published in Cell genomics (10.05.2023)
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Asthma-associated polymorphisms in 17q12-21 locus modulate methylation and gene expression of GSDMA in naïve CD4+ T cells
Madore, Anne-Marie, Pain, Lucile, Boucher-Lafleur, Anne-Marie, Morin, Andréanne, Meloche, Jolyane, Simon, Marie-Michelle, Ge, Bing, Kwan, Tony, Cheung, Warren A., Pastinen, Tomi, Laprise, Catherine
Published in Journal of genetics and genomics (20.03.2020)
Published in Journal of genetics and genomics (20.03.2020)
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Erratum: Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants
Allum, Fiona, Shao, Xiaojian, Guénard, Frédéric, Simon, Marie-Michelle, Busche, Stephan, Caron, Maxime, Lambourne, John, Lessard, Julie, Tandre, Karolina, Hedman, Åsa K, Kwan, Tony, Ge, Bing, Rönnblom, Lars, McCarthy, Mark I, Deloukas, Panos, Richmond, Todd, Burgess, Daniel, Spector, Timothy D, Tchernof, André, Marceau, Simon, Lathrop, Mark, Vohl, Marie-Claude, Pastinen, Tomi, Grundberg, Elin
Published in Nature communications (29.07.2015)
Published in Nature communications (29.07.2015)
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