Parkinson Disease Epidemiology, Pathology, Genetics, and Pathophysiology
Simon, David K, Tanner, Caroline M, Brundin, Patrik
Published in Clinics in geriatric medicine (01.02.2020)
Published in Clinics in geriatric medicine (01.02.2020)
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Journal Article
VPS35 and the mitochondria: Connecting the dots in Parkinson's disease pathophysiology
Cutillo, Gianni, Simon, David K., Eleuteri, Simona
Published in Neurobiology of disease (01.11.2020)
Published in Neurobiology of disease (01.11.2020)
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Journal Article
Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases
Espay, Alberto J, Vizcarra, Joaquin A, Marsili, Luca, Lang, Anthony E, Simon, David K, Merola, Aristide, Josephs, Keith A, Fasano, Alfonso, Morgante, Francesca, Savica, Rodolfo, Greenamyre, J Timothy, Cambi, Franca, Yamasaki, Tritia R, Tanner, Caroline M, Gan-Or, Ziv, Litvan, Irene, Mata, Ignacio F, Zabetian, Cyrus P, Brundin, Patrik, Fernandez, Hubert H, Standaert, David G, Kauffman, Marcelo A, Schwarzschild, Michael A, Sardi, S Pablo, Sherer, Todd, Perry, George, Leverenz, James B
Published in Neurology (12.02.2019)
Published in Neurology (12.02.2019)
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Journal Article
Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators
St-Pierre, Julie, Drori, Stavit, Uldry, Marc, Silvaggi, Jessica M., Rhee, James, Jäger, Sibylle, Handschin, Christoph, Zheng, Kangni, Lin, Jiandie, Yang, Wenli, Simon, David K., Bachoo, Robert, Spiegelman, Bruce M.
Published in Cell (20.10.2006)
Published in Cell (20.10.2006)
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Journal Article
Targeting energy metabolism via the mitochondrial pyruvate carrier as a novel approach to attenuate neurodegeneration
Quansah, Emmanuel, Peelaerts, Wouter, Langston, J William, Simon, David K, Colca, Jerry, Brundin, Patrik
Published in Molecular neurodegeneration (24.05.2018)
Published in Molecular neurodegeneration (24.05.2018)
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Journal Article
Knockout or inhibition of USP30 protects dopaminergic neurons in a Parkinson’s disease mouse model
Fang, Tracy-Shi Zhang, Sun, Yu, Pearce, Andrew C., Eleuteri, Simona, Kemp, Mark, Luckhurst, Christopher A., Williams, Rachel, Mills, Ross, Almond, Sarah, Burzynski, Laura, Márkus, Nóra M., Lelliott, Christopher J., Karp, Natasha A., Adams, David J., Jackson, Stephen P., Zhao, Jin-Feng, Ganley, Ian G., Thompson, Paul W., Balmus, Gabriel, Simon, David K.
Published in Nature communications (13.11.2023)
Published in Nature communications (13.11.2023)
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Journal Article
Meta-analysis of Parkinson's Disease: Identification of a novel locus, RIT2
Pankratz, Nathan, Beecham, Gary W., DeStefano, Anita L., Dawson, Ted M., Doheny, Kimberly F., Factor, Stewart A., Hamza, Taye H., Hung, Albert Y., Hyman, Bradley T., Ivinson, Adrian J., Krainc, Dmitri, Latourelle, Jeanne C., Clark, Lorraine N., Marder, Karen, Martin, Eden R., Mayeux, Richard, Ross, Owen A., Scherzer, Clemens R., Simon, David K., Tanner, Caroline, Vance, Jeffery M., Wszolek, Zbigniew K., Zabetian, Cyrus P., Myers, Richard H., Payami, Haydeh, Scott, William K., Foroud, Tatiana
Published in Annals of neurology (01.03.2012)
Published in Annals of neurology (01.03.2012)
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Journal Article
Oral N-acetyl-cysteine attenuates loss of dopaminergic terminals in alpha-synuclein overexpressing mice
Clark, Joanne, Clore, Elizabeth L, Zheng, Kangni, Adame, Anthony, Masliah, Eliezer, Simon, David K
Published in PloS one (23.08.2010)
Published in PloS one (23.08.2010)
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Journal Article
Somatic mitochondrial DNA mutations in early parkinson and incidental lewy body disease
Lin, Michael T., Cantuti-Castelvetri, Ippolita, Zheng, Kangni, Jackson, Katie E., Tan, Yong B., Arzberger, Thomas, Lees, Andrew J., Betensky, Rebecca A., Beal, M. Flint, Simon, David K.
Published in Annals of neurology (01.06.2012)
Published in Annals of neurology (01.06.2012)
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Journal Article
Pgc-1α overexpression downregulates Pitx3 and increases susceptibility to MPTP toxicity associated with decreased Bdnf
Clark, Joanne, Silvaggi, Jessica M, Kiselak, Tomas, Zheng, Kangni, Clore, Elizabeth L, Dai, Ying, Bass, Caroline E, Simon, David K
Published in PloS one (07.11.2012)
Published in PloS one (07.11.2012)
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Journal Article
Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's disease
Clark, Joanne, Reddy, Sonika, Zheng, Kangni, Betensky, Rebecca A, Simon, David K
Published in BMC genetics (19.05.2011)
Published in BMC genetics (19.05.2011)
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Journal Article
Efficacy of Deep Brain Stimulation in a Patient with Genetically Confirmed Chorea-Acanthocytosis
Richard, Alby, Hsu, Joey, Baum, Patricia, Alterman, Ron, Simon, David K.
Published in Case reports in neurology (01.05.2019)
Published in Case reports in neurology (01.05.2019)
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Journal Article
Mitochondrial Cyclic AMP Response Element-binding Protein (CREB) Mediates Mitochondrial Gene Expression and Neuronal Survival
Lee, Junghee, Kim, Chun-Hyung, Simon, David K., Aminova, Lyaylya R., Andreyev, Alexander Y., Kushnareva, Yulia E., Murphy, Anne N., Lonze, Bonnie E., Kim, Kwang-Soo, Ginty, David D., Ferrante, Robert J., Ryu, Hoon, Ratan, Rajiv R.
Published in The Journal of biological chemistry (09.12.2005)
Published in The Journal of biological chemistry (09.12.2005)
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Journal Article
Associations between exercise classes and self-reported exercise by people with Parkinson’s disease at Parkinson’s foundation centers of excellence
Nettnin, Ella, Burrows, Stephanie, Miao, Guanhong, Wu, Samuel S., Simon, David K., Rafferty, Miriam R.
Published in Clinical parkinsonism & related disorders (01.01.2022)
Published in Clinical parkinsonism & related disorders (01.01.2022)
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Journal Article
Mitochondrial DNA mutations in Parkinson's disease brain
Simon, David K, Matott, Joanne Clark, Espinosa, Janaina, Abraham, Neeta A
Published in Acta neuropathologica communications (29.04.2017)
Published in Acta neuropathologica communications (29.04.2017)
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Journal Article
Do mtDNA deletions drive premature aging in mtDNA mutator mice?
Kraytsberg, Yevgenya, Simon, David K., Turnbull, Douglas M., Khrapko, Konstantin
Published in Aging cell (01.08.2009)
Published in Aging cell (01.08.2009)
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