SLAMF receptors negatively regulate B cell receptor signaling in chronic lymphocytic leukemia via recruitment of prohibitin-2
von Wenserski, Lisa, Schultheiß, Christoph, Bolz, Sarah, Schliffke, Simon, Simnica, Donjete, Willscher, Edith, Gerull, Helwe, Wolters-Eisfeld, Gerrit, Riecken, Kristoffer, Fehse, Boris, Altfeld, Marcus, Nollau, Peter, Binder, Mascha
Published in Leukemia (01.04.2021)
Published in Leukemia (01.04.2021)
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Journal Article
Azacitidine-induced reconstitution of the bone marrow T cell repertoire is associated with superior survival in AML patients
Grimm, Juliane, Simnica, Donjete, Jäkel, Nadja, Paschold, Lisa, Willscher, Edith, Schulze, Susann, Dierks, Christine, Al-Ali, Haifa Kathrin, Binder, Mascha
Published in Blood cancer journal (New York) (28.01.2022)
Published in Blood cancer journal (New York) (28.01.2022)
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Journal Article
Evolutionary clonal trajectories in nodular lymphocyte-predominant Hodgkin lymphoma with high risk of transformation
Paschold, Lisa, Willscher, Edith, Bein, Julia, Vornanen, Martine, Eichenauer, Dennis A., Simnica, Donjete, Thiele, Benjamin, Wickenhauser, Claudia, Rosenwald, Andreas, Bernd, Heinz-Wolfram, Klapper, Wolfram, Feller, Alfred C., Ott, German, Fend, Falko, Hartmann, Sylvia, Binder, Mascha
Published in Haematologica (Roma) (01.10.2021)
Published in Haematologica (Roma) (01.10.2021)
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Journal Article
Subclonal heterogeneity sheds light on the transformation trajectory in IGLV3-21R110 chronic lymphocytic leukemia
Paschold, Lisa, Simnica, Donjete, Brito, Ramon Benitez, Zhang, Tianjiao, Schultheiß, Christoph, Dierks, Christine, Binder, Mascha
Published in Blood cancer journal (New York) (30.03.2022)
Published in Blood cancer journal (New York) (30.03.2022)
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Journal Article
T cell receptor next-generation sequencing reveals cancer-associated repertoire metrics and reconstitution after chemotherapy in patients with hematological and solid tumors
Simnica, Donjete, Akyüz, Nuray, Schliffke, Simon, Mohme, Malte, v.Wenserski, Lisa, Mährle, Thorben, Fanchi, Lorenzo F., Lamszus, Katrin, Binder, Mascha
Published in Oncoimmunology (02.11.2019)
Published in Oncoimmunology (02.11.2019)
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Journal Article
Characterization of the T cell receptor repertoire and melanoma tumor microenvironment upon combined treatment with ipilimumab and hTERT vaccination
Ellingsen, Espen Basmo, Bounova, Gergana, Kerzeli, Iliana, Anzar, Irantzu, Simnica, Donjete, Aamdal, Elin, Guren, Tormod, Clancy, Trevor, Mezheyeuski, Artur, Inderberg, Else Marit, Mangsbo, Sara M, Binder, Mascha, Hovig, Eivind, Gaudernack, Gustav
Published in Journal of translational medicine (11.09.2022)
Published in Journal of translational medicine (11.09.2022)
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Journal Article
Targeting the Mutational Landscape of Bystander Cells: Drug-Promoted Blood Cancer From High-Prevalence Pre-neoplasias in Patients on BRAF Inhibitors
Simnica, Donjete, Ittrich, Harald, Bockemeyer, Carsten, Stein, Alexander, Binder, Mascha
Published in Frontiers in oncology (11.09.2020)
Published in Frontiers in oncology (11.09.2020)
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Journal Article
Dietary-Induced Bacterial Metabolites Reduce Inflammation and Inflammation-Associated Cancer via Vitamin D Pathway
O'Mahony, Caitlin, Clooney, Adam, Clarke, Siobhan F, Aguilera, Mònica, Gavin, Aisling, Simnica, Donjete, Ahern, Mary, Fanning, Aine, Stanley, Maurice, Rubio, Raul Cabrera, Patterson, Elaine, Marques, Tatiana, Wall, Rebecca, Houston, Aileen, Mahmoud, Amr, Bennett, Michael W, Stanton, Catherine, Claesson, Marcus J, Cotter, Paul D, Shanahan, Fergus, Joyce, Susan A, Melgar, Silvia
Published in International journal of molecular sciences (18.01.2023)
Published in International journal of molecular sciences (18.01.2023)
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Journal Article
Inflammasome Signaling Regulates the Microbial–Neuroimmune Axis and Visceral Pain in Mice
Aguilera, Mònica, Rossini, Valerio, Hickey, Ana, Simnica, Donjete, Grady, Fiona, Felice, Valeria D., Moloney, Amy, Pawley, Lauren, Fanning, Aine, McCarthy, Lorraine, O’Mahony, Siobhan M., Cryan, John F., Nally, Ken, Shanahan, Fergus, Melgar, Silvia
Published in International journal of molecular sciences (01.08.2021)
Published in International journal of molecular sciences (01.08.2021)
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Journal Article
PD-L1 Amino Acid Position 88 Represents a Hotspot for PD-L1 Stability With Relevance for PD-L1 Inhibition
Claaß, Luise Victoria, Schultheiß, Christoph, Scholz, Rebekka, Paschold, Lisa, Simnica, Donjete, Heinemann, Volker, Stintzing, Sebastian, Binder, Mascha
Published in Frontiers in oncology (22.07.2022)
Published in Frontiers in oncology (22.07.2022)
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Journal Article
Deep sequencing of bone marrow microenvironments of patients with del(5q) myelodysplastic syndrome reveals imprints of antigenic selection as well as generation of novel T-cell clusters as a response pattern to lenalidomide
Mährle, Thorben, Akyüz, Nuray, Fuchs, Pim, Bonzanni, Nicola, Simnica, Donjete, Germing, Ulrich, Asemissen, Anne Marie, Jann, Johann Christoph, Nolte, Florian, Hofmann, Wolf-Karsten, Nowak, Daniel, Binder, Mascha
Published in Haematologica (Roma) (01.07.2019)
Published in Haematologica (Roma) (01.07.2019)
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Journal Article
Translational analysis and final efficacy of the AVETUX trial - Avelumab, cetuximab and FOLFOX in metastatic colorectal cancer
Tintelnot, Joseph, Ristow, Inka, Sauer, Markus, Simnica, Donjete, Schultheiß, Christoph, Scholz, Rebekka, Goekkurt, Eray, von Wenserski, Lisa, Willscher, Edith, Paschold, Lisa, Lorenzen, Sylvie, Riera-Knorrenschild, Jorge, Depenbusch, Reinhard, Ettrich, Thomas J, Dörfel, Steffen, Al-Batran, Salah-Eddin, Karthaus, Meinolf, Pelzer, Uwe, Hinke, Axel, Bauer, Marcus, Massa, Chiara, Seliger, Barbara, Wickenhauser, Claudia, Bokemeyer, Carsten, Hegewisch-Becker, Susanna, Binder, Mascha, Stein, Alexander
Published in Frontiers in oncology (20.12.2022)
Published in Frontiers in oncology (20.12.2022)
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Journal Article
High-Throughput Immunogenetics Reveals a Lack of Physiological T Cell Clusters in Patients With Autoimmune Cytopenias
Simnica, Donjete, Schliffke, Simon, Schultheiß, Christoph, Bonzanni, Nicola, Fanchi, Lorenzo F, Akyüz, Nuray, Gösch, Barbara, Casar, Christian, Thiele, Benjamin, Schlüter, Janina, Lohse, Ansgar W, Binder, Mascha
Published in Frontiers in immunology (21.08.2019)
Published in Frontiers in immunology (21.08.2019)
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Journal Article
Rapid Hypermutation B Cell Trajectory Recruits Previously Primed B Cells Upon Third SARS-Cov-2 mRNA Vaccination
Paschold, Lisa, Klee, Bianca, Gottschick, Cornelia, Willscher, Edith, Diexer, Sophie, Schultheiß, Christoph, Simnica, Donjete, Sedding, Daniel, Girndt, Matthias, Gekle, Michael, Mikolajczyk, Rafael, Binder, Mascha
Published in Frontiers in immunology (09.05.2022)
Published in Frontiers in immunology (09.05.2022)
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Journal Article
Maturation trajectories and transcriptional landscape of plasmablasts and autoreactive B cells in COVID-19
Schultheiß, Christoph, Paschold, Lisa, Willscher, Edith, Simnica, Donjete, Wöstemeier, Anna, Muscate, Franziska, Wass, Maxi, Eisenmann, Stephan, Dutzmann, Jochen, Keyßer, Gernot, Gagliani, Nicola, Binder, Mascha
Published in iScience (19.11.2021)
Published in iScience (19.11.2021)
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Journal Article
PD-L1 targeting and subclonal immune escape mediated by PD-L1 mutations in metastatic colorectal cancer
Stein, Alexander, Simnica, Donjete, Schultheiß, Christoph, Scholz, Rebekka, Tintelnot, Joseph, Gökkurt, Eray, von Wenserski, Lisa, Willscher, Edith, Paschold, Lisa, Sauer, Markus, Lorenzen, Sylvie, Riera-Knorrenschild, Jorge, Depenbusch, Reinhard, Ettrich, Thomas J, Dörfel, Steffen, Al-Batran, Salah-Eddin, Karthaus, Meinolf, Pelzer, Uwe, Waberer, Lisa, Hinke, Axel, Bauer, Marcus, Massa, Chiara, Seliger, Barbara, Wickenhauser, Claudia, Bokemeyer, Carsten, Hegewisch-Becker, Susanna, Binder, Mascha
Published in Journal for immunotherapy of cancer (01.07.2021)
Published in Journal for immunotherapy of cancer (01.07.2021)
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Journal Article
Landscape of T‐cell repertoires with public COVID‐19‐associated T‐cell receptors in pre‐pandemic risk cohorts
Simnica, Donjete, Schultheiß, Christoph, Mohme, Malte, Paschold, Lisa, Willscher, Edith, Fitzek, Antonia, Püschel, Klaus, Matschke, Jakob, Ciesek, Sandra, Sedding, Daniel G, Zhao, Yu, Gagliani, Nicola, Maringer, Yacine, Walz, Juliane S, Heide, Janna, Schulze‐zur‐Wiesch, Julian, Binder, Mascha
Published in Clinical & Translational Immunology (2021)
Published in Clinical & Translational Immunology (2021)
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Journal Article
Web Resource
Neoantigen T-Cell Receptor Gene Therapy in Pancreatic Cancer
Simnica, Donjetë, Kobold, Sebastian, Tran, Eric, Urba, Walter J., Leidner, Rom
Published in The New England journal of medicine (11.08.2022)
Published in The New England journal of medicine (11.08.2022)
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Journal Article
Next-Generation Sequencing of T and B Cell Receptor Repertoires from COVID-19 Patients Showed Signatures Associated with Severity of Disease
Schultheiß, Christoph, Paschold, Lisa, Simnica, Donjete, Mohme, Malte, Willscher, Edith, von Wenserski, Lisa, Scholz, Rebekka, Wieters, Imke, Dahlke, Christine, Tolosa, Eva, Sedding, Daniel G., Ciesek, Sandra, Addo, Marylyn, Binder, Mascha
Published in Immunity (18.08.2020)
Published in Immunity (18.08.2020)
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Journal Article
Web Resource
Homologous recombination repair deficient prostate cancer represents an immunologically distinct subtype
van Wilpe, Sandra, Simnica, Donjetë, Slootbeek, Peter, van Ee, Thomas, Pamidimarri Naga, Samhita, Gorris, Mark A. J., van der Woude, Lieke L., Sultan, Shabaz, Koornstra, Rutger H. T., van Oort, Inge M., Gerritsen, Winald R., Kroeze, Leonie I., Simons, Michiel, van Leenders, Geert J. L. H., Binder, Mascha, de Vries, I. Jolanda M., Mehra, Niven
Published in Oncoimmunology (31.12.2022)
Published in Oncoimmunology (31.12.2022)
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Journal Article