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Published in Nature biotechnology (01.03.2003)
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Morphological Deconvolution of Beta-Lactam Polyspecificity in E. coli
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Optimization of novel monobactams with activity against carbapenem-resistant Enterobacteriaceae – Identification of LYS228
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Published in Bioorganic & medicinal chemistry letters (15.02.2018)
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Mode of Action of the Monobactam LYS228 and Mechanisms Decreasing In Vitro Susceptibility in Escherichia coli and Klebsiella pneumoniae
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Published in Antimicrobial agents and chemotherapy (01.10.2018)
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Potent Nonimmunosuppressive Cyclophilin Inhibitors With Improved Pharmaceutical Properties and Decreased Transporter Inhibition
Fu, Jiping, Tjandra, Meiliana, Becker, Christopher, Bednarczyk, Dallas, Capparelli, Michael, Elling, Robert, Hanna, Imad, Fujimoto, Roger, Furegati, Markus, Karur, Subramanian, Kasprzyk, Theresa, Knapp, Mark, Leung, Kwan, Li, Xiaolin, Lu, Peichao, Mergo, Wosenu, Miault, Charlotte, Ng, Simon, Parker, David, Peng, Yunshan, Roggo, Silvio, Rivkin, Alexey, Simmons, Robert L, Wang, Michael, Wiedmann, Brigitte, Weiss, Andrew H, Xiao, Linda, Xie, Lili, Xu, Wenjian, Yifru, Aregahegn, Yang, Shengtian, Zhou, Bo, Sweeney, Zachary K
Published in Journal of medicinal chemistry (23.10.2014)
Published in Journal of medicinal chemistry (23.10.2014)
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IID572: A New Potentially Best-In-Class β‑Lactamase Inhibitor
Reck, Folkert, Bermingham, Alun, Blais, Johanne, Casarez, Anthony, Colvin, Richard, Dean, Charles R, Furegati, Markus, Gamboa, Luis, Growcott, Ellena, Li, Cindy, Lopez, Sara, Metzger, Louis, Nocito, Sandro, Ossola, Flavio, Phizackerley, Kaci, Rasper, Dita, Shaul, Jacob, Shen, Xiaoyu, Simmons, Robert L, Tang, Dazhi, Tashiro, Kyuto, Yue, Qin
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Published in ACS infectious diseases (12.07.2019)
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Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery
Erlanson, Daniel A., Arndt, Joseph W., Cancilla, Mark T., Cao, Kathy, Elling, Robert A., English, Nicki, Friedman, Jessica, Hansen, Stig K., Hession, Cathy, Joseph, Ingrid, Kumaravel, Gnanasambandam, Lee, Wen-Cherng, Lind, Ken E., McDowell, Robert S., Miatkowski, Konrad, Nguyen, Christine, Nguyen, Thinh B., Park, Sophia, Pathan, Nuzhat, Penny, David M., Romanowski, Michael J., Scott, Daniel, Silvian, Laura, Simmons, Robert L., Tangonan, Bradley T., Yang, Wenjin, Sun, Lihong
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
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Size Matters and How You Measure It: A Gram-Negative Antibacterial Example Exceeding Typical Molecular Weight Limits
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Published in ACS infectious diseases (11.10.2019)
Published in ACS infectious diseases (11.10.2019)
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Development of a cyclosporin A derivative with excellent anti-hepatitis C virus potency
Fu, Jiping, Becker, Christopher, Cao, Li, Capparelli, Michael, Denay, Regis, Fujimoto, Roger, Gai, Yu, Gao, Zhaobo, Guenat, Christian, Karur, Subramanian, Kim, Hongyong, Li, Weikuan, Li, Xiaolin, Li, Wei, Lochmann, Thomas, Lu, Amy, Lu, Peichao, Luneau, Alexandre, Meier, Nicole, Mergo, Wosenu, Ng, Simon, Parker, David, Peng, Yunshan, Riss, Bernard, Rivkin, Alexey, Roggo, Silvio, Schroeder, Harald, Schuerch, Friedrich, Simmons, Robert L., Sun, Feng, Sweeney, Zachary K., Tjandra, Meiliana, Wang, Michael, Wang, Ruidong, Weiss, Andrew H., Wenger, Nicolas, Wu, Quanbing, Xiong, Xin, Xu, Su, Xu, Wenjian, Yifru, Aregahegn, Zhao, Jibin, Zhou, Jianguang, Zürcher, Christian, Gallou, Fabrice
Published in Bioorganic & medicinal chemistry (15.02.2018)
Published in Bioorganic & medicinal chemistry (15.02.2018)
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Discovery of an Aurora kinase inhibitor through site-specific dynamic combinatorial chemistry
Cancilla, Mark T., He, Molly M., Viswanathan, Nina, Simmons, Robert L., Taylor, Meggin, Fung, Amy D., Cao, Kathy, Erlanson, Daniel A.
Published in Bioorganic & medicinal chemistry (15.07.2008)
Published in Bioorganic & medicinal chemistry (15.07.2008)
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Discovery of a New Phosphotyrosine Mimetic for PTP1B Using Breakaway Tethering
Erlanson, Daniel A, McDowell, Robert S, He, Molly M, Randal, Mike, Simmons, Robert L, Kung, Jenny, Waight, Andrew, Hansen, Stig K
Published in Journal of the American Chemical Society (14.05.2003)
Published in Journal of the American Chemical Society (14.05.2003)
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