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Published in Nature genetics (01.03.2012)
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WAVE2 suppresses mTOR activation to maintain T cell homeostasis and prevent autoimmunity
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Published in Science (American Association for the Advancement of Science) (26.03.2021)
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Myelin basic protein mRNA levels affect myelin sheath dimensions, architecture, plasticity, and density of resident glial cells
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Published in Glia (01.10.2024)
Published in Glia (01.10.2024)
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Pervasive sharing of genetic effects in autoimmune disease
Cotsapas, Chris, Voight, Benjamin F, Rossin, Elizabeth, Lage, Kasper, Neale, Benjamin M, Wallace, Chris, Abecasis, Gonçalo R, Barrett, Jeffrey C, Behrens, Timothy, Cho, Judy, De Jager, Philip L, Elder, James T, Graham, Robert R, Gregersen, Peter, Klareskog, Lars, Siminovitch, Katherine A, van Heel, David A, Wijmenga, Cisca, Worthington, Jane, Todd, John A, Hafler, David A, Rich, Stephen S, Daly, Mark J
Published in PLoS genetics (01.08.2011)
Published in PLoS genetics (01.08.2011)
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A Role for Noncoding Variation in Schizophrenia
Roussos, Panos, Mitchell, Amanda C., Voloudakis, Georgios, Fullard, John F., Pothula, Venu M., Tsang, Jonathan, Stahl, Eli A., Georgakopoulos, Anastasios, Ruderfer, Douglas M., Charney, Alexander, Okada, Yukinori, Siminovitch, Katherine A., Worthington, Jane, Padyukov, Leonid, Klareskog, Lars, Gregersen, Peter K., Plenge, Robert M., Raychaudhuri, Soumya, Fromer, Menachem, Purcell, Shaun M., Brennand, Kristen J., Robakis, Nikolaos K., Schadt, Eric E., Akbarian, Schahram, Sklar, Pamela
Published in Cell reports (Cambridge) (20.11.2014)
Published in Cell reports (Cambridge) (20.11.2014)
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The autoimmune disease-associated PTPN22 variant promotes calpain-mediated Lyp/Pep degradation associated with lymphocyte and dendritic cell hyperresponsiveness
Siminovitch, Katherine A, Zhang, Jinyi, Zahir, Naima, Jiang, Qiuhong, Miliotis, Helen, Heyraud, Stephanie, Meng, Xianwang, Dong, Baoxia, Xie, Gang, Qiu, Frank, Hao, Zhenyue, McCulloch, Christopher A, Keystone, Edward C, Peterson, Alan C
Published in Nature genetics (01.09.2011)
Published in Nature genetics (01.09.2011)
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Bayesian inference analyses of the polygenic architecture of rheumatoid arthritis
Stahl, Eli A, Wegmann, Daniel, Trynka, Gosia, Gutierrez-Achury, Javier, Do, Ron, Voight, Benjamin F, Kraft, Peter, Chen, Robert, Kallberg, Henrik J, Kurreeman, Fina A S, Kathiresan, Sekar, Wijmenga, Cisca, Gregersen, Peter K, Alfredsson, Lars, Siminovitch, Katherine A, Worthington, Jane, de Bakker, Paul I W, Raychaudhuri, Soumya, Plenge, Robert M
Published in Nature genetics (01.05.2012)
Published in Nature genetics (01.05.2012)
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Identification of Functional and Expression Polymorphisms Associated With Risk for Antineutrophil Cytoplasmic Autoantibody–Associated Vasculitis
Merkel, Peter A., Xie, Gang, Monach, Paul A., Ji, Xuemei, Ciavatta, Dominic J., Byun, Jinyoung, Pinder, Benjamin D., Zhao, Ai, Zhang, Jinyi, Tadesse, Yohannes, Qian, David, Weirauch, Matthew, Nair, Rajan, Tsoi, Alex, Pagnoux, Christian, Carette, Simon, Chung, Sharon, Cuthbertson, David, Davis, John C., Dellaripa, Paul F., Forbess, Lindsy, Gewurz‐Singer, Ora, Hoffman, Gary S., Khalidi, Nader, Koening, Curry, Langford, Carol A., Mahr, Alfred D., McAlear, Carol, Moreland, Larry, Seo, E. Philip, Specks, Ulrich, Spiera, Robert F., Sreih, Antoine, St.Clair, E. William, Stone, John H., Ytterberg, Steven R., Elder, James T., Qu, Jia, Ochi, Toshiki, Hirano, Naoto, Edberg, Jeffrey C., Falk, Ronald J., Amos, Christopher I., Siminovitch, Katherine A.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2017)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2017)
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Primary Biliary Cirrhosis Associated with HLA, IL12A, and IL12RB2 Variants
Hirschfield, Gideon M, Liu, Xiangdong, Xu, Chun, Lu, Yan, Lu, Yue, Xie, Gang, Gu, Xiangjun, Walker, Erin J, Jing, Kaiyan, Juran, Brian D, Mason, Andrew L, Myers, Robert P, Peltekian, Kevork M, Ghent, Cameron N, Coltescu, Catalina, Atkinson, Elizabeth J, Heathcote, E. Jenny, Lazaridis, Konstantinos N, Amos, Christopher I, Siminovitch, Katherine A
Published in The New England journal of medicine (11.06.2009)
Published in The New England journal of medicine (11.06.2009)
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The Arabidopsis SWI2/SNF2 chromatin Remodeler BRAHMA regulates polycomb function during vegetative development and directly activates the flowering repressor gene SVP
Li, Chenlong, Chen, Chen, Gao, Lei, Yang, Songguang, Nguyen, Vi, Shi, Xuejiang, Siminovitch, Katherine, Kohalmi, Susanne E, Huang, Shangzhi, Wu, Keqiang, Chen, Xuemei, Cui, Yuhai
Published in PLoS genetics (01.01.2015)
Published in PLoS genetics (01.01.2015)
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Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis
Han, Younghun, Byun, Jinyoung, Zhu, Catherine, Sun, Ryan, Roh, Julia Y., Cordell, Heather J., Lee, Hyun-Sung, Shaw, Vikram R., Kang, Sung Wook, Razjouyan, Javad, Cooley, Matthew A., Hassan, Manal M., Siminovitch, Katherine A., Folseraas, Trine, Ellinghaus, David, Bergquist, Annika, Rushbrook, Simon M., Franke, Andre, Karlsen, Tom H., Lazaridis, Konstantinos N., McGlynn, Katherine A., Roberts, Lewis R., Amos, Christopher I.
Published in Nature communications (24.02.2023)
Published in Nature communications (24.02.2023)
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Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population
Okada, Yukinori, Terao, Chikashi, Ikari, Katsunori, Kochi, Yuta, Ohmura, Koichiro, Suzuki, Akari, Kawaguchi, Takahisa, Stahl, Eli A, Kurreeman, Fina A S, Nishida, Nao, Ohmiya, Hiroko, Myouzen, Keiko, Takahashi, Meiko, Sawada, Tetsuji, Nishioka, Yuichi, Yukioka, Masao, Matsubara, Tsukasa, Wakitani, Shigeyuki, Teshima, Ryota, Tohma, Shigeto, Takasugi, Kiyoshi, Shimada, Kota, Murasawa, Akira, Honjo, Shigeru, Matsuo, Keitaro, Tanaka, Hideo, Tajima, Kazuo, Suzuki, Taku, Iwamoto, Takuji, Kawamura, Yoshiya, Tanii, Hisashi, Okazaki, Yuji, Sasaki, Tsukasa, Gregersen, Peter K, Padyukov, Leonid, Worthington, Jane, Siminovitch, Katherine A, Lathrop, Mark, Taniguchi, Atsuo, Takahashi, Atsushi, Tokunaga, Katsushi, Kubo, Michiaki, Nakamura, Yusuke, Kamatani, Naoyuki, Mimori, Tsuneyo, Plenge, Robert M, Yamanaka, Hisashi, Momohara, Shigeki, Yamada, Ryo, Matsuda, Fumihiko, Yamamoto, Kazuhiko
Published in Nature genetics (01.05.2012)
Published in Nature genetics (01.05.2012)
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Genetics and the environment converge to dysregulate N-glycosylation in multiple sclerosis
Mkhikian, Haik, Grigorian, Ani, Li, Carey F., Chen, Hung-Lin, Newton, Barbara, Zhou, Raymond W., Beeton, Christine, Torossian, Sevan, Tatarian, Gevork Grikor, Lee, Sung-Uk, Lau, Ken, Walker, Erin, Siminovitch, Katherine A., Chandy, K. George, Yu, Zhaoxia, Dennis, James W., Demetriou, Michael
Published in Nature communications (31.05.2011)
Published in Nature communications (31.05.2011)
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Comprehensive Profiling of the Rheumatoid Arthritis Antibody Repertoire
Lo, Ken C., Sullivan, Eric, Bannen, Ryan M., Jin, Huiyan, Rowe, Mark, Li, Hanying, Pinapati, Richard S., Cartwright, Adam J., Tan, John C., Patel, Jigar, Keystone, Edward C., Siminovitch, Katherine A.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.02.2020)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.02.2020)
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Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis
Seldin, Michael F, Liu, Xiangdong, Invernizzi, Pietro, Lu, Yue, Kosoy, Roman, Lu, Yan, Bianchi, Ilaria, Podda, Mauro, Xu, Chun, Xie, Gang, Macciardi, Fabio, Selmi, Carlo, Lupoli, Sara, Shigeta, Russell, Ransom, Michael, Lleo, Ana, Lee, Annette T, Mason, Andrew L, Myers, Robert P, Peltekian, Kevork M, Ghent, Cameron N, Bernuzzi, Francesca, Zuin, Massimo, Rosina, Floriano, Borghesio, Elisabetta, Floreani, Annarosa, Lazzari, Roberta, Niro, Grazia, Andriulli, Angelo, Muratori, Luigi, Muratori, Paolo, Almasio, Piero L, Andreone, Pietro, Margotti, Marzia, Brunetto, Maurizia, Coco, Barbara, Alvaro, Domenico, Bragazzi, Maria C, Marra, Fabio, Pisano, Alessandro, Rigamonti, Cristina, Colombo, Massimo, Marzioni, Marco, Benedetti, Antonio, Fabris, Luca, Strazzabosco, Mario, Portincasa, Piero, Palmieri, Vincenzo O, Tiribelli, Claudio, Croce, Lory, Bruno, Savino, Rossi, Sonia, Vinci, Maria, Prisco, Cleofe, Mattalia, Alberto, Toniutto, Pierluigi, Picciotto, Antonio, Galli, Andrea, Ferrari, Carlo, Colombo, Silvia, Casella, Giovanni, Morini, Lorenzo, Caporaso, Nicola, Colli, Agostino, Spinzi, Giancarlo, Montanari, Renzo, Gregersen, Peter K, Heathcote, E Jenny, Hirschfield, Gideon M, Siminovitch, Katherine A, Amos, Christopher I, Gershwin, M Eric
Published in Nature genetics (01.08.2010)
Published in Nature genetics (01.08.2010)
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Uptake of apoptotic DC converts immature DC into tolerogenic DC that induce differentiation of Foxp3⁺ Treg
Kushwah, Rahul, Wu, Jing, Oliver, Jordan R, Jiang, George, Zhang, Jinyi, Siminovitch, Katherine A, Hu, Jim
Published in European journal of immunology (01.04.2010)
Published in European journal of immunology (01.04.2010)
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