Structural dynamics of receptor recognition and pH-induced dissociation of full-length Clostridioides difficile Toxin B
Jiang, Mengqiu, Shin, Joonyoung, Simeon, Rudo, Chang, Jeng-Yih, Meng, Ran, Wang, Yuhang, Shinde, Omkar, Li, Pingwei, Chen, Zhilei, Zhang, Junjie
Published in PLoS biology (24.03.2022)
Published in PLoS biology (24.03.2022)
Get full text
Journal Article
Selection and characterization of ultrahigh potency designed ankyrin repeat protein inhibitors of C. difficile toxin B
Simeon, Rudo, Jiang, Mengqiu, Chamoun-Emanuelli, Ana M, Yu, Hua, Zhang, Yongrong, Meng, Ran, Peng, Zeyu, Jakana, Joanita, Zhang, Junjie, Feng, Hanping, Chen, Zhilei
Published in PLoS biology (24.06.2019)
Published in PLoS biology (24.06.2019)
Get full text
Journal Article
Protease-stable DARPins as promising oral therapeutics
Simeon, Rudo A, Zeng, Yu, Chonira, Vikas, Aguirre, Andrea Martinez, Lasagna, Mauricio, Baloh, Marko, Sorg, Joseph A, Tommos, Cecilia, Chen, Zhilei
Published in Protein engineering, design and selection (15.02.2021)
Published in Protein engineering, design and selection (15.02.2021)
Get full text
Journal Article
Phenothiazines Inhibit Hepatitis C Virus Entry, Likely by Increasing the Fluidity of Cholesterol-Rich Membranes
CHAMOUN-EMANUELLI, Ana M, PECHEUR, Eve-Isabelle, SIMEON, Rudo L, DA HUANG, CREMER, Paul S, ZHILEI CHEN
Published in Antimicrobial Agents and Chemotherapy (01.06.2013)
Published in Antimicrobial Agents and Chemotherapy (01.06.2013)
Get full text
Journal Article
Designed Ankyrin Repeat Protein (DARPin) Neutralizers of TcdB from Clostridium difficile Ribotype 027
Peng, Zeyu, Simeon, Rudo, Mitchell, Samuel B, Zhang, Junjie, Feng, Hanping, Chen, Zhilei
Published in mSphere (02.10.2019)
Published in mSphere (02.10.2019)
Get full text
Journal Article
Correction: Selection and characterization of ultrahigh potency designed ankyrin repeat protein inhibitors of C. difficile toxin B
Simeon, Rudo, Jiang, Mengqiu, Chamoun-Emanuelli, Ana M, Yu, Hua, Zhang, Yongrong, Meng, Ran, Peng, Zeyu, Jakana, Joanita, Zhang, Junjie, Feng, Hanping, Chen, Zhilei
Published in PLoS biology (04.10.2019)
Published in PLoS biology (04.10.2019)
Get full text
Journal Article
PD 404,182 Is a Virocidal Small Molecule That Disrupts Hepatitis C Virus and Human Immunodeficiency Virus
Chamoun, Ana Maria, Chockalingam, Karuppiah, Bobardt, Michael, Simeon, Rudo, Chang, Jinhong, Gallay, Philippe, Chen, Zhilei
Published in Antimicrobial Agents and Chemotherapy (01.02.2012)
Published in Antimicrobial Agents and Chemotherapy (01.02.2012)
Get full text
Journal Article
A Multi-Specific DARPin Potently Neutralizes Shiga Toxin 2 via Simultaneous Modulation of Both Toxin Subunits
Zeng, Yu, Jiang, Mengqiu, Robinson, Sally, Peng, Zeyu, Chonira, Vikas, Simeon, Rudo, Tzipori, Saul, Zhang, Junjie, Chen, Zhilei
Published in Bioengineering (Basel) (27.09.2022)
Published in Bioengineering (Basel) (27.09.2022)
Get full text
Journal Article
Discovery and Characterization of a New Cell-Penetrating Protein
Simeon, Rudo L, Chamoun, Ana Maria, McMillin, Thomas, Chen, Zhilei
Published in ACS chemical biology (20.12.2013)
Published in ACS chemical biology (20.12.2013)
Get full text
Journal Article
De Novo Isolation & Affinity Maturation of yeast-displayed Virion-binding human fibronectin domains by flow cytometric screening against Virions
Heinzelman, Pete, Low, Alyssa, Simeon, Rudo, Wright, Gus A, Chen, Zhilei
Published in Journal of biological engineering (16.10.2019)
Published in Journal of biological engineering (16.10.2019)
Get full text
Journal Article
Creation and characterization of a cell-death reporter cell line for hepatitis C virus infection
Chen, Zhilei, Simeon, Rudo L., Chockalingam, Karuppiah, Rice, Charles M.
Published in Antiviral research (01.05.2010)
Published in Antiviral research (01.05.2010)
Get full text
Journal Article
Potent and pan-neutralization of SARS-CoV-2 variants of concern by DARPins
Chonira, Vikas, Kwon, Young Do, Gorman, Jason, Case, James Brett, Ku, Zhiqiang, Simeon, Rudo, Casner, Ryan G, Harris, Darcy R, Olia, Adam S, Stephens, Tyler, Shapiro, Lawrence, Boyd, Hannah, Tsybovsky, Yaroslav, Krammer, Florian, Diamond, Michael S, Kwong, Peter D, An, Zhiqiang, Chen, Zhilei
Published in bioRxiv (31.05.2022)
Published in bioRxiv (31.05.2022)
Get full text
Journal Article
Paper
Correction to: Protease-stable DARPins as promising oral therapeutics
Simeon, Rudo A, Zeng, Yu, Chonira, Vikas, Aguirre, Andrea Martinez, Lasagna, Mauricio, Baloh, Marko, Sorg, Joseph A, Tommos, Cecilia, Chen, Zhilei
Published in Protein engineering, design and selection (17.02.2022)
Published in Protein engineering, design and selection (17.02.2022)
Get full text
Journal Article
A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins
Chonira, Vikas, Kwon, Young D., Gorman, Jason, Case, James Brett, Ku, Zhiqiang, Simeon, Rudo, Casner, Ryan G., Harris, Darcy R., Olia, Adam S., Stephens, Tyler, Shapiro, Lawrence, Bender, Michael F., Boyd, Hannah, Teng, I-Ting, Tsybovsky, Yaroslav, Krammer, Florian, Zhang, Ningyan, Diamond, Michael S., Kwong, Peter D., An, Zhiqiang, Chen, Zhilei
Published in Nature chemical biology (01.03.2023)
Published in Nature chemical biology (01.03.2023)
Get full text
Journal Article
A Cell Protection Screen Reveals Potent Inhibitors of Multiple Stages of the Hepatitis C Virus Life Cycle
Chockalingam, Karuppiah, Simeon, Rudo, Rice, Charles, Chen, Zhilei
Published in Antiviral research (01.04.2010)
Published in Antiviral research (01.04.2010)
Get full text
Journal Article