Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of preclinical and clinical nanoparticles
Vu, Vivian P., Gifford, Geoffrey B., Chen, Fangfang, Benasutti, Halli, Wang, Guankui, Groman, Ernest V., Scheinman, Robert, Saba, Laura, Moghimi, Seyed Moein, Simberg, Dmitri
Published in Nature nanotechnology (01.03.2019)
Published in Nature nanotechnology (01.03.2019)
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Journal Article
Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo
Chen, Fangfang, Wang, Guankui, Griffin, James I., Brenneman, Barbara, Banda, Nirmal K., Holers, V. Michael, Backos, Donald S., Wu, LinPing, Moghimi, Seyed Moein, Simberg, Dmitri
Published in Nature nanotechnology (01.04.2017)
Published in Nature nanotechnology (01.04.2017)
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Journal Article
Roadmap and strategy for overcoming infusion reactions to nanomedicines
Szebeni, Janos, Simberg, Dmitri, González-Fernández, África, Barenholz, Yechezkel, Dobrovolskaia, Marina A.
Published in Nature nanotechnology (01.12.2018)
Published in Nature nanotechnology (01.12.2018)
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Journal Article
Dendrimer end-terminal motif-dependent evasion of human complement and complement activation through IgM hitchhiking
Wu, Lin-Ping, Ficker, Mario, Christensen, Jørn B., Simberg, Dmitri, Trohopoulos, Panagiotis N., Moghimi, Seyed M.
Published in Nature communications (11.08.2021)
Published in Nature communications (11.08.2021)
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Journal Article
Mechanisms and Barriers in Cancer Nanomedicine: Addressing Challenges, Looking for Solutions
Anchordoquy, Thomas J, Barenholz, Yechezkel, Boraschi, Diana, Chorny, Michael, Decuzzi, Paolo, Dobrovolskaia, Marina A, Farhangrazi, Z. Shadi, Farrell, Dorothy, Gabizon, Alberto, Ghandehari, Hamidreza, Godin, Biana, La-Beck, Ninh M, Ljubimova, Julia, Moghimi, S. Moein, Pagliaro, Len, Park, Ji-Ho, Peer, Dan, Ruoslahti, Erkki, Serkova, Natalie J, Simberg, Dmitri
Published in ACS nano (24.01.2017)
Published in ACS nano (24.01.2017)
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Journal Article
C1q-Mediated Complement Activation and C3 Opsonization Trigger Recognition of Stealth Poly(2-methyl-2-oxazoline)-Coated Silica Nanoparticles by Human Phagocytes
Tavano, Regina, Gabrielli, Luca, Lubian, Elisa, Fedeli, Chiara, Visentin, Silvia, Polverino De Laureto, Patrizia, Arrigoni, Giorgio, Geffner-Smith, Alessandra, Chen, Fangfang, Simberg, Dmitri, Morgese, Giulia, Benetti, Edmondo M, Wu, Linping, Moghimi, Seyed Moein, Mancin, Fabrizio, Papini, Emanuele
Published in ACS nano (26.06.2018)
Published in ACS nano (26.06.2018)
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Journal Article
Systematic Surface Engineering of Magnetic Nanoworms for In vivo Tumor Targeting
Park, Ji‐Ho, von Maltzahn, Geoffrey, Zhang, Lianglin, Derfus, Austin M., Simberg, Dmitri, Harris, Todd J., Ruoslahti, Erkki, Bhatia, Sangeeta N., Sailor, Michael J.
Published in Small (Weinheim an der Bergstrasse, Germany) (20.03.2009)
Published in Small (Weinheim an der Bergstrasse, Germany) (20.03.2009)
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Journal Article
Biomimetic amplification of nanoparticle homing to tumors
Simberg, Dmitri, Duza, Tasmia, Park, Ji Ho, Essler, Markus, Pilch, Jan, Zhang, Lianglin, Derfus, Austin M, Yang, Meng, Hoffman, Robert M, Bhatia, Sangeeta, Sailor, Michael J, Ruoslahti, Erkki
Published in Proceedings of the National Academy of Sciences - PNAS (16.01.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (16.01.2007)
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Journal Article
Dual-Porosity Hollow Nanoparticles for the Immunoprotection and Delivery of Nonhuman Enzymes
Ortac, Inanc, Simberg, Dmitri, Yeh, Ya-san, Yang, Jian, Messmer, Bradley, Trogler, William C, Tsien, Roger Y, Esener, Sadik
Published in Nano letters (11.06.2014)
Published in Nano letters (11.06.2014)
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Journal Article
Mechanisms of complement activation by dextran-coated superparamagnetic iron oxide (SPIO) nanoworms in mouse versus human serum
Banda, Nirmal K, Mehta, Gaurav, Chao, Ying, Wang, Guankui, Inturi, Swetha, Fossati-Jimack, Liliane, Botto, Marina, Wu, LinPing, Moghimi, Seyed Moein, Simberg, Dmitri
Published in Particle and fibre toxicology (26.11.2014)
Published in Particle and fibre toxicology (26.11.2014)
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Journal Article
Surface Modification of Erythrocytes with Lipid Anchors: Structure–Activity Relationship for Optimal Membrane Incorporation, in vivo Retention, and Immunocompatibility
Gaikwad, Hanmant, Wang, Guankui, Li, Yue, Bourne, David, Simberg, Dmitri
Published in Advanced NanoBiomed Research (Online) (01.08.2022)
Published in Advanced NanoBiomed Research (Online) (01.08.2022)
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Journal Article
Publisher Correction: Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of preclinical and clinical nanoparticles
Vu, Vivian P., Gifford, Geoffrey B., Chen, Fangfang, Benasutti, Halli, Wang, Guankui, Groman, Ernest V., Scheinman, Robert, Saba, Laura, Moghimi, Seyed Moein, Simberg, Dmitri
Published in Nature nanotechnology (01.03.2019)
Published in Nature nanotechnology (01.03.2019)
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Journal Article
Activation of Human Complement System by Dextran-Coated Iron Oxide Nanoparticles Is Not Affected by Dextran/Fe Ratio, Hydroxyl Modifications, and Crosslinking
Wang, Guankui, Chen, Fangfang, Banda, Nirmal K, Holers, V Michael, Wu, LinPing, Moghimi, S Moein, Simberg, Dmitri
Published in Frontiers in immunology (10.10.2016)
Published in Frontiers in immunology (10.10.2016)
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Journal Article
Recognition of Dextran–Superparamagnetic Iron Oxide Nanoparticle Conjugates (Feridex) via Macrophage Scavenger Receptor Charged Domains
Chao, Ying, Makale, Milan, Karmali, Priya Prakash, Sharikov, Yuriy, Tsigelny, Igor, Merkulov, Sergei, Kesari, Santosh, Wrasidlo, Wolf, Ruoslahti, Erkki, Simberg, Dmitri
Published in Bioconjugate chemistry (16.05.2012)
Published in Bioconjugate chemistry (16.05.2012)
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Journal Article
C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Attenuates Arthritis in Mice
Banda, Nirmal K, Tomlinson, Stephen, Scheinman, Robert I, Ho, Nhu, Ramirez, Joseline Ramos, Mehta, Gaurav, Wang, Guankui, Vu, Vivian Pham, Simberg, Dmitri, Kulik, Liudmila, Holers, V Michael
Published in Frontiers in immunology (16.10.2020)
Published in Frontiers in immunology (16.10.2020)
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Journal Article
Cyanine lipids promote the shedding of extracellular vesicles from cell membranes
Simberg, Dmitri, Gaikwad, Hanmant, Siegel, David, Barnes, Ashlynn, Kanada, Masamitsu, Wan, Chun, Shen, Jingshi, Balyasnikova, Irina
Published in Precision nanomedicine (15.09.2023)
Published in Precision nanomedicine (15.09.2023)
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Journal Article
Isolation of rare tumor cells from blood cells with buoyant immuno-microbubbles
Shi, Guixin, Cui, Wenjin, Benchimol, Michael, Liu, Yu-Tsueng, Mattrey, Robert F, Mukthavaram, Rajesh, Kesari, Santosh, Esener, Sadik C, Simberg, Dmitri
Published in PloS one (13.03.2013)
Published in PloS one (13.03.2013)
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