Transcriptional repression of estrogen receptor alpha by YAP reveals the Hippo pathway as therapeutic target for ER+ breast cancer
Ma, Shenghong, Tang, Tracy, Probst, Gary, Konradi, Andrei, Jin, Chunyu, Li, Fulong, Gutkind, J. Silvio, Fu, Xiang-Dong, Guan, Kun-Liang
Published in Nature communications (25.02.2022)
Published in Nature communications (25.02.2022)
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B Cells Improve Overall Survival in HPV-Associated Squamous Cell Carcinomas and Are Activated by Radiation and PD-1 Blockade
Kim, Sangwoo S, Shen, Sarek, Miyauchi, Sayuri, Sanders, P Dominick, Franiak-Pietryga, Ida, Mell, Loren, Gutkind, J Silvio, Cohen, Ezra E W, Califano, Joseph A, Sharabi, Andrew B
Published in Clinical cancer research (01.07.2020)
Published in Clinical cancer research (01.07.2020)
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Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry
Feng, Xiaodong, Degese, Maria Sol, Iglesias-Bartolome, Ramiro, Vaque, Jose P., Molinolo, Alfredo A., Rodrigues, Murilo, Zaidi, M. Raza, Ksander, Bruce R., Merlino, Glenn, Sodhi, Akrit, Chen, Qianming, Gutkind, J. Silvio
Published in Cancer cell (16.06.2014)
Published in Cancer cell (16.06.2014)
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Journal Article
Immune Modulation of Head and Neck Squamous Cell Carcinoma and the Tumor Microenvironment by Conventional Therapeutics
Miyauchi, Sayuri, Kim, Sangwoo S, Pang, John, Gold, Kathryn A, Gutkind, J Silvio, Califano, Joseph A, Mell, Loren K, Cohen, Ezra E W, Sharabi, Andrew B
Published in Clinical cancer research (15.07.2019)
Published in Clinical cancer research (15.07.2019)
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Journal Article
Transcriptional signature primes human oral mucosa for rapid wound healing
Iglesias-Bartolome, Ramiro, Uchiyama, Akihiko, Molinolo, Alfredo A, Abusleme, Loreto, Brooks, Stephen R, Callejas-Valera, Juan Luis, Edwards, Dean, Doci, Colleen, Asselin-Labat, Marie-Liesse, Onaitis, Mark W, Moutsopoulos, Niki M, Gutkind, J S, Morasso, Maria I
Published in Science translational medicine (25.07.2018)
Published in Science translational medicine (25.07.2018)
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Journal Article
mTOR co-targeting strategies for head and neck cancer therapy
Wang, Zhiyong, Valera, Juan Callejas, Zhao, Xuefeng, Chen, Qianming, Silvio Gutkind, J.
Published in Cancer and metastasis reviews (01.09.2017)
Published in Cancer and metastasis reviews (01.09.2017)
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Journal Article
Tipifarnib as a Precision Therapy for HRAS -Mutant Head and Neck Squamous Cell Carcinomas
Gilardi, Mara, Wang, Zhiyong, Proietto, Marco, Chillà, Anastasia, Calleja-Valera, Juan Luis, Goto, Yusuke, Vanoni, Marco, Janes, Matthew R, Mikulski, Zbigniew, Gualberto, Antonio, Molinolo, Alfredo A, Ferrara, Napoleone, Gutkind, J Silvio, Burrows, Francis
Published in Molecular cancer therapeutics (01.09.2020)
Published in Molecular cancer therapeutics (01.09.2020)
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Journal Article
The NOTCH4 - HEY1 Pathway Induces Epithelial-Mesenchymal Transition in Head and Neck Squamous Cell Carcinoma
Fukusumi, Takahito, Guo, Theresa W, Sakai, Akihiro, Ando, Mizuo, Ren, Shuling, Haft, Sunny, Liu, Chao, Amornphimoltham, Panomwat, Gutkind, J Silvio, Califano, Joseph A
Published in Clinical cancer research (01.02.2018)
Published in Clinical cancer research (01.02.2018)
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Journal Article
Illuminating the Onco-GPCRome: Novel G protein–coupled receptor-driven oncocrine networks and targets for cancer immunotherapy
Wu, Victoria, Yeerna, Huwate, Nohata, Nijiro, Chiou, Joshua, Harismendy, Olivier, Raimondi, Francesco, Inoue, Asuka, Russell, Robert B., Tamayo, Pablo, Gutkind, J. Silvio
Published in The Journal of biological chemistry (19.07.2019)
Published in The Journal of biological chemistry (19.07.2019)
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Journal Article
Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4
Wang, Zhiyong, Wu, Victoria H., Allevato, Michael M., Gilardi, Mara, He, Yudou, Luis Callejas-Valera, Juan, Vitale-Cross, Lynn, Martin, Daniel, Amornphimoltham, Panomwat, Mcdermott, James, Yung, Bryan S., Goto, Yusuke, Molinolo, Alfredo A., Sharabi, Andrew B., Cohen, Ezra E. W., Chen, Qianming, Lyons, J. Guy, Alexandrov, Ludmil B., Gutkind, J. Silvio
Published in Nature communications (05.12.2019)
Published in Nature communications (05.12.2019)
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Journal Article
mTOR Inhibition Prevents Epithelial Stem Cell Senescence and Protects from Radiation-Induced Mucositis
Iglesias-Bartolome, Ramiro, Patel, Vyomesh, Cotrim, Ana, Leelahavanichkul, Kantima, Molinolo, Alfredo A., Mitchell, James B., Gutkind, J. Silvio
Published in Cell stem cell (07.09.2012)
Published in Cell stem cell (07.09.2012)
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The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer
O'Hayre, Morgan, Vázquez-Prado, José, Kufareva, Irina, Stawiski, Eric W., Handel, Tracy M., Seshagiri, Somasekar, Gutkind, J. Silvio
Published in Nature reviews. Cancer (01.06.2013)
Published in Nature reviews. Cancer (01.06.2013)
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Journal Article
Assembly and activation of the Hippo signalome by FAT1 tumor suppressor
Martin, Daniel, Degese, Maria S., Vitale-Cross, Lynn, Iglesias-Bartolome, Ramiro, Valera, Juan Luis Callejas, Wang, Zhiyong, Feng, Xiaodong, Yeerna, Huwate, Vadmal, Vachan, Moroishi, Toshiro, Thorne, Rick F., Zaida, Moraima, Siegele, Bradford, Cheong, Sok C., Molinolo, Alfredo A., Samuels, Yardena, Tamayo, Pablo, Guan, Kun Liang, Lippman, Scott M., Lyons, J. Guy, Gutkind, J. Silvio
Published in Nature communications (09.07.2018)
Published in Nature communications (09.07.2018)
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Journal Article
Measurement of biomarker proteins for point-of-care early detection and monitoring of cancer
Rusling, James F, Kumar, Challa V, Gutkind, J. Silvio, Patel, Vyomesh
Published in Analyst (London) (01.01.2010)
Published in Analyst (London) (01.01.2010)
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Journal Article
HPV E2, E4, E5 drive alternative carcinogenic pathways in HPV positive cancers
Ren, Shuling, Gaykalova, Daria A., Guo, Theresa, Favorov, Alexander V., Fertig, Elana J., Tamayo, Pablo, Callejas-Valera, Juan Luis, Allevato, Mike, Gilardi, Mara, Santos, Jessica, Fukusumi, Takahito, Sakai, Akihiro, Ando, Mizuo, Sadat, Sayed, Liu, Chao, Xu, Guorong, Fisch, Kathleen M., Wang, Zhiyong, Molinolo, Alfredo A., Gutkind, J. Silvio, Ideker, Trey, Koch, Wayne M., Califano, Joseph A.
Published in Oncogene (01.10.2020)
Published in Oncogene (01.10.2020)
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