Activation of RNase L is dependent on OAS3 expression during infection with diverse human viruses
Li, Yize, Banerjee, Shuvojit, Wang, Yuyan, Goldstein, Stephen A., Dong, Beihua, Gaughan, Christina, Silverman, Robert H., Weiss, Susan R.
Published in Proceedings of the National Academy of Sciences - PNAS (23.02.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (23.02.2016)
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Journal Article
Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication
Kindler, Eveline, Gil-Cruz, Cristina, Spanier, Julia, Li, Yize, Wilhelm, Jochen, Rabouw, Huib H, Züst, Roland, Hwang, Mihyun, V'kovski, Philip, Stalder, Hanspeter, Marti, Sabrina, Habjan, Matthias, Cervantes-Barragan, Luisa, Elliot, Ruth, Karl, Nadja, Gaughan, Christina, van Kuppeveld, Frank J M, Silverman, Robert H, Keller, Markus, Ludewig, Burkhard, Bergmann, Cornelia C, Ziebuhr, John, Weiss, Susan R, Kalinke, Ulrich, Thiel, Volker
Published in PLoS pathogens (01.02.2017)
Published in PLoS pathogens (01.02.2017)
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COVID-19: Coronavirus replication, pathogenesis, and therapeutic strategies
Bergmann, Cornelia C, Silverman, Robert H
Published in Cleveland Clinic journal of medicine (01.06.2020)
Published in Cleveland Clinic journal of medicine (01.06.2020)
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Journal Article
SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial-derived cells and cardiomyocytes
Li, Yize, Renner, David M., Comar, Courtney E., Whelan, Jillian N., Reyes, Hanako M., Cardenas-Diaz, Fabian Leonardo, Truitt, Rachel, Tan, Li Hui, Dong, Beihua, Alysandratos, Konstantinos Dionysios, Huang, Jessie, Palmer, James N., Adappa, Nithin D., Kohanski, Michael A., Kotton, Darrell N., Silverman, Robert H., Yang, Wenli, Morrisey, Edward E., Cohen, Noam A., Weiss, Susan R.
Published in Proceedings of the National Academy of Sciences - PNAS (20.04.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (20.04.2021)
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Journal Article
Antagonism of the Interferon-Induced OAS-RNase L Pathway by Murine Coronavirus ns2 Protein Is Required for Virus Replication and Liver Pathology
Zhao, Ling, Jha, Babal K., Wu, Ashley, Elliott, Ruth, Ziebuhr, John, Gorbalenya, Alexander E., Silverman, Robert H., Weiss, Susan R.
Published in Cell host & microbe (14.06.2012)
Published in Cell host & microbe (14.06.2012)
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Journal Article
RNase L Activates the NLRP3 Inflammasome during Viral Infections
Chakrabarti, Arindam, Banerjee, Shuvojit, Franchi, Luigi, Loo, Yueh-Ming, Gale, Michael, Núñez, Gabriel, Silverman, Robert H.
Published in Cell host & microbe (08.04.2015)
Published in Cell host & microbe (08.04.2015)
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Journal Article
molecular basis for selective inhibition of unconventional mRNA splicing by an IRE1-binding small molecule
Cross, Benedict C. S, Bond, Peter J, Sadowski, Pawel G, Jha, Babal Kant, Zak, Jaroslav, Goodman, Jonathan M, Silverman, Robert H, Neubert, Thomas A, Baxendale, Ian R, Ron, David, Harding, Heather P
Published in Proceedings of the National Academy of Sciences - PNAS (10.04.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (10.04.2012)
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Journal Article
Interferons at age 50: past, current and future impact on biomedicine
Borden, Ernest C, Sen, Ganes C, Uze, Gilles, Silverman, Robert H, Ransohoff, Richard M, Foster, Graham R, Stark, George R
Published in Nature reviews. Drug discovery (01.12.2007)
Published in Nature reviews. Drug discovery (01.12.2007)
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Journal Article
Cytosolic double-stranded RNA activates the NLRP3 inflammasome via MAVS-induced membrane permeabilization and K+ efflux
Franchi, Luigi, Eigenbrod, Tatjana, Muñoz-Planillo, Raúl, Ozkurede, Ulas, Kim, Yun-Gi, Arindam, Chakrabarti, Gale, Jr, Michael, Silverman, Robert H, Colonna, Marco, Akira, Shizuo, Núñez, Gabriel
Published in The Journal of immunology (1950) (15.10.2014)
Published in The Journal of immunology (1950) (15.10.2014)
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Journal Article
Zika Virus Production Is Resistant to RNase L Antiviral Activity
Whelan, Jillian N, Li, Yize, Silverman, Robert H, Weiss, Susan R
Published in Journal of virology (15.08.2019)
Published in Journal of virology (15.08.2019)
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Journal Article
OAS-RNase L innate immune pathway mediates the cytotoxicity of a DNA-demethylating drug
Banerjee, Shuvojit, Gusho, Elona, Gaughan, Christina, Dong, Beihua, Gu, Xiaorong, Holvey-Bates, Elise, Talukdar, Manisha, Li, Yize, Weiss, Susan R., Sicheri, Frank, Saunthararajah, Yogen, Stark, George R., Silverman, Robert H.
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (12.03.2019)
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Journal Article
Ribonuclease L mediates the cell-lethal phenotype of double-stranded RNA editing enzyme ADAR1 deficiency in a human cell line
Li, Yize, Banerjee, Shuvojit, Goldstein, Stephen A, Dong, Beihua, Gaughan, Christina, Rath, Sneha, Donovan, Jesse, Korennykh, Alexei, Silverman, Robert H, Weiss, Susan R
Published in eLife (31.03.2017)
Published in eLife (31.03.2017)
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Journal Article
Homologous 2′,5′-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity
Zhang, Rong, Jha, Babal K., Ogden, Kristen M., Dong, Beihua, Zhao, Ling, Elliott, Ruth, Patton, John T., Silverman, Robert H., Weiss, Susan R.
Published in Proceedings of the National Academy of Sciences - PNAS (06.08.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (06.08.2013)
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Journal Article
Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation
Thornbrough, Joshua M, Jha, Babal K, Yount, Boyd, Goldstein, Stephen A, Li, Yize, Elliott, Ruth, Sims, Amy C, Baric, Ralph S, Silverman, Robert H, Weiss, Susan R
Published in mBio (29.03.2016)
Published in mBio (29.03.2016)
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Journal Article
Dimeric Structure of Pseudokinase RNase L Bound to 2-5A Reveals a Basis for Interferon-Induced Antiviral Activity
Huang, Hao, Zeqiraj, Elton, Dong, Beihua, Jha, Babal Kant, Duffy, Nicole M., Orlicky, Stephen, Thevakumaran, Neroshan, Talukdar, Manisha, Pillon, Monica C., Ceccarelli, Derek F., Wan, Leo C.K., Juang, Yu-Chi, Mao, Daniel Y.L., Gaughan, Christina, Brinton, Margo A., Perelygin, Andrey A., Kourinov, Igor, Guarné, Alba, Silverman, Robert H., Sicheri, Frank
Published in Molecular cell (23.01.2014)
Published in Molecular cell (23.01.2014)
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Journal Article
Initiation of a ZAKα-dependent ribotoxic stress response by the innate immunity endoribonuclease RNase L
Xi, Jiajia, Snieckute, Goda, Martínez, José Francisco, Arendrup, Frederic Schrøder Wenzel, Asthana, Abhishek, Gaughan, Christina, Lund, Anders H., Bekker-Jensen, Simon, Silverman, Robert H.
Published in Cell reports (Cambridge) (23.04.2024)
Published in Cell reports (Cambridge) (23.04.2024)
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Journal Article
RNase L Triggers Autophagy in Response to Viral Infections
CHAKRABARTI, Arindam, KUMAR GHOSH, Prabar, BANERJEE, Shuvojit, GAUGHAN, Christina, SILVERMAN, Robert H
Published in Journal of Virology (01.10.2012)
Published in Journal of Virology (01.10.2012)
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Journal Article
Activation of IFN-β expression by a viral mRNA through RNase L and MDA5
Luthra, Priya, Sun, Dengyun, Silverman, Robert H, He, Biao
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.2011)
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