Deficiency in Acyl-CoA:Wax Alcohol Acyltransferase 2 causes evaporative dry eye disease by abolishing biosynthesis of wax esters
Widjaja-Adhi, Made Airanthi K, Silvaroli, Josie A, Chelstowska, Sylwia, Trischman, Thomas, Bederman, Ilya, Sayegh, Rony, Golczak, Marcin
Published in The FASEB journal (01.10.2020)
Published in The FASEB journal (01.10.2020)
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Journal Article
Kidney toxicity of the BRAF-kinase inhibitor vemurafenib is driven by off-target ferrochelatase inhibition
Bai, Yuntao, Kim, Ji Young, Bisunke, Bijay, Jayne, Laura A., Silvaroli, Josie A., Balzer, Michael S., Gandhi, Megha, Huang, Kevin M., Sander, Veronika, Prosek, Jason, Cianciolo, Rachel E., Baker, Sharyn D., Sparreboom, Alex, Jhaveri, Kenar D., Susztak, Katalin, Bajwa, Amandeep, Pabla, Navjot Singh
Published in Kidney international (01.12.2021)
Published in Kidney international (01.12.2021)
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Journal Article
Molecular Basis for Vitamin A Uptake and Storage in Vertebrates
Chelstowska, Sylwia, Widjaja-Adhi, Made Airanthi K, Silvaroli, Josie A, Golczak, Marcin
Published in Nutrients (26.10.2016)
Published in Nutrients (26.10.2016)
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Journal Article
Book Review
Molecular basis for the interaction of cellular retinol binding protein 2 (CRBP2) with nonretinoid ligands
Silvaroli, Josie A., Plau, Jacqueline, Adams, Charlie H., Banerjee, Surajit, Widjaja-Adhi, Made Airanthi K., Blaner, William S., Golczak, Marcin
Published in Journal of lipid research (01.01.2021)
Published in Journal of lipid research (01.01.2021)
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Journal Article
Discovery and characterization of a specific inhibitor of serine-threonine kinase cyclin-dependent kinase-like 5 (CDKL5) demonstrates role in hippocampal CA1 physiology
Castano, Anna, Silvestre, Margaux, Wells, Carrow I, Sanderson, Jennifer L, Ferrer, Carla A, Ong, Han Wee, Lang, Yi, Richardson, William, Silvaroli, Josie A, Bashore, Frances M, Smith, Jeffery L, Genereux, Isabelle M, Dempster, Kelvin, Drewry, David H, Pabla, Navlot S, Bullock, Alex N, Benke, Tim A, Ultanir, Sila K, Axtman, Alison D
Published in eLife (25.07.2023)
Published in eLife (25.07.2023)
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Journal Article
Interaction of Antifungal Drugs with CYP3A- and OATP1B-Mediated Venetoclax Elimination
Eisenmann, Eric D, Garrison, Dominique A, Talebi, Zahra, Jin, Yan, Silvaroli, Josie A, Kim, Jin-Gyu, Sparreboom, Alex, Savona, Michael R, Mims, Alice S, Baker, Sharyn D
Published in Pharmaceutics (23.03.2022)
Published in Pharmaceutics (23.03.2022)
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Journal Article
Role of the CDKL1-SOX11 signaling axis in acute kidney injury
Silvaroli, Josie A., Martinez, Gabriela V., Vanichapol, Thitinee, Davidson, Alan J., Zepeda-Orozco, Diana, Pabla, Navjot S., Kim, Ji Young
Published in American journal of physiology. Renal physiology (01.09.2024)
Published in American journal of physiology. Renal physiology (01.09.2024)
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Journal Article
Ligand Binding Induces Conformational Changes in Human Cellular Retinol-binding Protein 1 (CRBP1) Revealed by Atomic Resolution Crystal Structures
Silvaroli, Josie A., Arne, Jason M., Chelstowska, Sylwia, Kiser, Philip D., Banerjee, Surajit, Golczak, Marcin
Published in The Journal of biological chemistry (15.04.2016)
Published in The Journal of biological chemistry (15.04.2016)
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Journal Article
Intestinal Enteroendocrine Cell Signaling: Retinol-binding Protein 2 and Retinoid Actions
Calderon, Rossana M, Smith, Christopher A, Miedzybrodzka, Emily L, Silvaroli, Josie A, Golczak, Marcin, Gribble, Fiona M, Reimann, Frank, Blaner, William S
Published in Endocrinology (Philadelphia) (01.07.2022)
Published in Endocrinology (Philadelphia) (01.07.2022)
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Journal Article
Genome-Wide CRISPR Screen Identifies Phospholipid Scramblase 3 as the Biological Target of Mitoprotective Drug SS-31
Silvaroli, Josie A, Bisunke, Bijay, Kim, Ji Young, Stayton, Amanda, Jayne, Laura A, Martinez, Shirely A, Nguyen, Christopher, Patel, Prisha S, Vanichapol, Thitinee, Verma, Vivek, Akhter, Juheb, Bolisetty, Subhashini, Madhavan, Sethu M, Kuscu, Cem, Coss, Christopher C, Zepeda-Orozco, Diana, Parikh, Samir V, Satoskar, Anjali A, Davidson, Alan J, Eason, James D, Szeto, Hazel H, Pabla, Navjot S, Bajwa, Amandeep
Published in Journal of the American Society of Nephrology (01.06.2024)
Published in Journal of the American Society of Nephrology (01.06.2024)
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Journal Article
Zinc finger protein 24-dependent transcription factor SOX9 up-regulation protects tubular epithelial cells during acute kidney injury
Kim, Ji Young, Silvaroli, Josie A., Martinez, Gabriela Vasquez, Bisunke, Bijay, Luna Ramirez, Alanys V., Jayne, Laura A., Feng, Mei Ji He Ho, Girotra, Bhavya, Acosta Martinez, Shirely M., Vermillion, Corynne R., Karel, Isaac Z., Ferrell, Nicholas, Weisleder, Noah, Chung, Sangwoon, Christman, John W., Brooks, Craig R., Madhavan, Sethu M., Hoyt, Kari R., Cianciolo, Rachel E., Satoskar, Anjali A., Zepeda-Orozco, Diana, Sullivan, Jennifer C., Davidson, Alan J., Bajwa, Amandeep, Pabla, Navjot Singh
Published in Kidney international (01.06.2023)
Published in Kidney international (01.06.2023)
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Journal Article
Abnormal Cannabidiol Modulates Vitamin A Metabolism by Acting as a Competitive Inhibitor of CRBP1
Silvaroli, Josie A, Widjaja-Adhi, Made Airanthi K, Trischman, Thomas, Chelstowska, Sylwia, Horwitz, Samantha, Banerjee, Surajit, Kiser, Philip D, Blaner, William S, Golczak, Marcin
Published in ACS chemical biology (15.03.2019)
Published in ACS chemical biology (15.03.2019)
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Journal Article
Discovery of a Potent and Selective CDKL5/GSK3 Chemical Probe That Is Neuroprotective
Ong, Han Wee, Liang, Yi, Richardson, William, Lowry, Emily R., Wells, Carrow I., Chen, Xiangrong, Silvestre, Margaux, Dempster, Kelvin, Silvaroli, Josie A., Smith, Jeffery L., Wichterle, Hynek, Pabla, Navjot S., Ultanir, Sila K., Bullock, Alex N., Drewry, David H., Axtman, Alison D.
Published in ACS chemical neuroscience (03.05.2023)
Published in ACS chemical neuroscience (03.05.2023)
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Journal Article
Systematic Evaluation of Tyrosine Kinase Inhibitors as OATP1B1 Substrates Using a Competitive Counterflow Screen
Drabison, Thomas, Boeckman, Mike, Yang, Yan, Huang, Kevin M., de Bruijn, Peter, Nepal, Mahesh R., Silvaroli, Josie A., Chowdhury, Anika T., Eisenmann, Eric D., Cheng, Xiaolin, Pabla, Navjotsingh, Mathijssen, Ron H.J., Baker, Sharyn D., Hu, Shuiying, Sparreboom, Alex, Talebi, Zahra
Published in Cancer research communications (23.09.2024)
Published in Cancer research communications (23.09.2024)
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Journal Article
Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight
Lee, Seung-Ah, Yang, Kryscilla Jian Zhang, Brun, Pierre-Jacques, Silvaroli, Josie A, Yuen, Jason J, Shmarakov, Igor, Jiang, Hongfeng, Feranil, Jun B, Li, Xueting, Lackey, Atreju I, Krężel, Wojciech, Leibel, Rudolph L, Libien, Jenny, Storch, Judith, Golczak, Marcin, Blaner, William S
Published in Science advances (01.03.2020)
Published in Science advances (01.03.2020)
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Journal Article
ZFP24 Drives Sox9 Upregulation During AKI: FR-OR09
Kim, Ji Young, Silvaroli, Josie A., Pabla, Navjot Singh P.
Published in Journal of the American Society of Nephrology (01.10.2021)
Published in Journal of the American Society of Nephrology (01.10.2021)
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Journal Article
Genome-Wide CRISPR Screen Reveals That Elamipretide (SS-31) Mediated PLSCR3 Activation Mitigates Mitochondrial Dysfunction During AKI: TH-OR45
Silvaroli, Josie A., Bisunke, Bijay, Kim, Ji Young, Pabla, Navjot Singh P., Bajwa, Amandeep
Published in Journal of the American Society of Nephrology (01.11.2022)
Published in Journal of the American Society of Nephrology (01.11.2022)
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Journal Article