Key Topics in Molecular Docking for Drug Design
Torres, Pedro H M, Sodero, Ana C R, Jofily, Paula, Silva-Jr, Floriano P
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Published in International journal of molecular sciences (15.09.2019)
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Exploring the DNA binding/cleavage, cellular accumulation and topoisomerase inhibition of 2-hydroxy-3-(aminomethyl)-1,4-naphthoquinone Mannich bases and their platinum(II) complexes
Neves, Amanda P., Pereira, Michelle X.G., Peterson, Erica J., Kipping, Ralph, Vargas, Maria D., Silva-Jr, Floriano P., Carneiro, J. Walkimar M., Farrell, Nicholas P.
Published in Journal of inorganic biochemistry (01.02.2013)
Published in Journal of inorganic biochemistry (01.02.2013)
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On the three-finger protein domain fold and CD59-like proteins in Schistosoma mansoni
Farias, Leonardo P, Krautz-Peterson, Greice, Tararam, Cibele A, Araujo-Montoya, Bogar O, Fraga, Tatiana R, Rofatto, Henrique K, Silva, Jr, Floriano P, Isaac, Lourdes, Da'dara, Akram A, Wilson, R Alan, Shoemaker, Charles B, Leite, Luciana C C
Published in PLoS neglected tropical diseases (01.10.2013)
Published in PLoS neglected tropical diseases (01.10.2013)
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Editorial: Current approaches in infectious disease drug discovery
Silva-Jr, Floriano P, Panda, Siva S, Andrade, Carolina Horta, Furnham, Nicholas
Published in Frontiers in chemistry (30.11.2022)
Published in Frontiers in chemistry (30.11.2022)
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Ethyl Diazoacetate
Aquino, Gabriel A. S., Silva-Jr, Floriano P., Ferreira, Sabrina B.
Published in SynOpen (2017) (01.03.2023)
Published in SynOpen (2017) (01.03.2023)
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Proteomic and bioinformatic analysis of Trypanosoma cruzi chemotherapy and potential drug targets: new pieces for an old puzzle
Sadok Menna-Barreto, Rubem Figueiredo, Belloze, Kele Teixeira, Perales, Jonas, Silva, Jr, Floriano Paes
Published in Current drug targets (01.03.2014)
Published in Current drug targets (01.03.2014)
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Insights into cytochrome bc1 complex binding mode of antimalarial 2-hydroxy-1,4-naphthoquinones through molecular modelling
Sodero, Ana Carolina Rennó, Abrahim-Vieira, Bárbara, Torres, Pedro Henrique Monteiro, Pascutti, Pedro Geraldo, Garcia, Célia Rs, Ferreira, Vitor Francisco, Rocha, David Rodrigues da, Ferreira, Sabrina Baptista, Silva, Jr, Floriano Paes
Published in Memórias do Instituto Oswaldo Cruz (01.04.2017)
Published in Memórias do Instituto Oswaldo Cruz (01.04.2017)
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N-acetyl-cysteine inhibits liver oxidative stress markers in BALB/c mice infected with Leishmania amazonensis
Gasparotto, Juciano, Kunzler, Alice, Senger, Mario Roberto, Souza, Celeste da Silva Freitas de, Simone, Salvatore Giovanni de, Bortolin, Rafael Calixto, Somensi, Nauana, Dal-Pizzol, Felipe, Moreira, José Claudio Fonseca, Abreu-Silva, Ana Lúcia, Calabrese, Kátia da Silva, Silva, Jr, Floriano Paes, Gelain, Daniel Pens
Published in Memórias do Instituto Oswaldo Cruz (01.02.2017)
Published in Memórias do Instituto Oswaldo Cruz (01.02.2017)
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New Imatinib Derivatives with Antiproliferative Activity against A549 and K562 Cancer Cells
Oliveira, Andressa, Moura, Stefany, Pimentel, Luiz, Neto, João, Dantas, Rafael, Silva-Jr, Floriano, Bastos, Monica, Boechat, Nubia
Published in Molecules (Basel, Switzerland) (24.01.2022)
Published in Molecules (Basel, Switzerland) (24.01.2022)
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Natural products targeting into cancer hallmarks: An update on caffeine, theobromine, and (+)-catechin
Cadoná, Francine C., Dantas, Rafael Ferreira, de Mello, Gabriela Haas, Silva-Jr, Floriano Paes
Published in Critical reviews in food science and nutrition (12.09.2022)
Published in Critical reviews in food science and nutrition (12.09.2022)
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Recent Advances on Targeting Proteases for Antiviral Development
Borges, Pedro Henrique Oliveira, Ferreira, Sabrina Baptista, Silva, Jr, Floriano Paes
Published in Viruses (27.02.2024)
Published in Viruses (27.02.2024)
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Past and future of trypanosomatids high-throughput phenotypic screening
Dantas, Rafael Ferreira, Torres-Santos, Eduardo Caio, Silva, Jr, Floriano Paes
Published in Memórias do Instituto Oswaldo Cruz (01.01.2022)
Published in Memórias do Instituto Oswaldo Cruz (01.01.2022)
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Synthesis and evaluation of the cytotoxic activity of 1,2-furanonaphthoquinones tethered to 1,2,3-1H-triazoles in myeloid and lymphoid leukemia cell lines
Cardoso, Mariana F.C., Rodrigues, Patrícia C., Oliveira, Maria Eduarda I.M., Gama, Ivson L., da Silva, Illana M.C.B., Santos, Isabela O., Rocha, David R., Pinho, Rosa T., Ferreira, Vitor F., de Souza, Maria Cecília B.V., da Silva, Fernando de C., Silva-Jr, Floriano Paes
Published in European journal of medicinal chemistry (12.09.2014)
Published in European journal of medicinal chemistry (12.09.2014)
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Kinetics Studies on the Inhibition Mechanism of Pancreatic α-Amylase by Glycoconjugated 1H-1,2,3-Triazoles: A New Class of Inhibitors with Hypoglycemiant Activity
Senger, Mario Roberto, Gomes, Lucas da Costa Andrade, Ferreira, Sabrina Baptista, Kaiser, Carlos Roland, Ferreira, Vitor Francisco, Silva Jr, Floriano Paes
Published in Chembiochem : a European journal of chemical biology (23.07.2012)
Published in Chembiochem : a European journal of chemical biology (23.07.2012)
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Fragment library screening by X-ray crystallography and binding site analysis on thioredoxin glutathione reductase of Schistosoma mansoni
de Souza Neto, Lauro Ribeiro, Montoya, Bogar Omar, Brandão-Neto, José, Verma, Anil, Bowyer, Sebastian, Moreira-Filho, José Teófilo, Dantas, Rafael Ferreira, Neves, Bruno Junior, Andrade, Carolina Horta, von Delft, Frank, Owens, Raymond J., Furnham, Nicholas, Silva-Jr, Floriano Paes
Published in Scientific reports (18.01.2024)
Published in Scientific reports (18.01.2024)
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Increased tau phosphorylation and receptor for advanced glycation endproducts (RAGE) in the brain of mice infected with Leishmania amazonensis
Gasparotto, Juciano, Senger, Mario Roberto, Kunzler, Alice, Degrossoli, Adriana, de Simone, Salvatore Giovanni, Bortolin, Rafael Calixto, Somensi, Nauana, Girardi, Carolina Saibro, de Souza, Celeste da Silva Freitas, Calabrese, Kátia da Silva, Dal-Pizzol, Felipe, Moreira, José Claudio Fonseca, Silva-Jr, Floriano Paes, Gelain, Daniel Pens
Published in Brain, behavior, and immunity (01.01.2015)
Published in Brain, behavior, and immunity (01.01.2015)
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Synthesis of new lophine-carbohydrate hybrids as cholinesterase inhibitors: cytotoxicity evaluation and molecular modeling
Lopes, João Paulo Bizarro, Silva, Luana, Ceschi, Marco Antonio, Lüdtke, Diogo Seibert, Zimmer, Aline Rigon, Ruaro, Thais Carine, Dantas, Rafael Ferreira, de Salles, Cristiane Martins Cardoso, Silva-Jr, Floriano Paes, Senger, Mario Roberto, Barbosa, Gisele, Lima, Lídia Moreira, Guedes, Isabella Alvim, Dardenne, Laurent Emmanuel
Published in MedChemComm (01.12.2019)
Published in MedChemComm (01.12.2019)
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FindTargetsWEB: A User-Friendly Tool for Identification of Potential Therapeutic Targets in Metabolic Networks of Bacteria
Merigueti, Thiago Castanheira, Carneiro, Marcia Weber, Carvalho-Assef, Ana Paula D'A, Silva-Jr, Floriano Paes, da Silva, Fabricio Alves Barbosa
Published in Frontiers in genetics (04.07.2019)
Published in Frontiers in genetics (04.07.2019)
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