Stat3 Activation Is Limiting for Reprogramming to Ground State Pluripotency
Yang, Jian, van Oosten, Anouk L., Theunissen, Thorold W., Guo, Ge, Silva, Jose C.R., Smith, Austin
Published in Cell stem cell (03.09.2010)
Published in Cell stem cell (03.09.2010)
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Why it is important to study human–monkey embryonic chimeras in a dish
De Los Angeles, Alejandro, Regenberg, Alan, Mascetti, Victoria, Benvenisty, Nissim, Church, George, Deng, Hongkui, Izpisua Belmonte, Juan Carlos, Ji, Weizhi, Koplin, Julian, Loh, Yuin-Han, Niu, Yuyu, Pei, Duanqing, Pera, Martin, Pho, Nam, Pinzon-Arteaga, Carlos, Saitou, Mitinori, Silva, Jose C. R., Tao, Tan, Trounson, Alan, Warrier, Tushar, Zambidis, Elias T.
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Self-renewing human naïve pluripotent stem cells dedifferentiate in 3D culture and form blastoids spontaneously
Guo, Mingyue, Wu, Jinyi, Chen, Chuanxin, Wang, Xinggu, Gong, An, Guan, Wei, Karvas, Rowan M., Wang, Kexin, Min, Mingwei, Wang, Yixuan, Theunissen, Thorold W., Gao, Shaorong, Silva, José C. R.
Published in Nature communications (22.01.2024)
Published in Nature communications (22.01.2024)
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Zfp281 mediates Nanog autorepression through recruitment of the NuRD complex and inhibits somatic cell reprogramming
Fidalgo, Miguel, Faiola, Francesco, Pereira, Carlos-Filipe, Ding, Junjun, Saunders, Arven, Gingold, Julian, Schaniel, Christoph, Lemischka, Ihor R, Silva, José C. R, Wang, Jianlong
Published in Proceedings of the National Academy of Sciences - PNAS (02.10.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (02.10.2012)
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StemBond hydrogels control the mechanical microenvironment for pluripotent stem cells
Labouesse, Céline, Tan, Bao Xiu, Agley, Chibeza C., Hofer, Moritz, Winkel, Alexander K., Stirparo, Giuliano G., Stuart, Hannah T., Verstreken, Christophe M., Mulas, Carla, Mansfield, William, Bertone, Paul, Franze, Kristian, Silva, José C. R., Chalut, Kevin J.
Published in Nature communications (21.10.2021)
Published in Nature communications (21.10.2021)
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One-step generation of conditional and reversible gene knockouts
Andersson-Rolf, Amanda, Mustata, Roxana C, Merenda, Alessandra, Kim, Jihoon, Perera, Sajith, Grego, Tiago, Andrews, Katie, Tremble, Katie, Silva, José C R, Fink, Juergen, Skarnes, William C, Koo, Bon-Kyoung
Published in Nature methods (01.03.2017)
Published in Nature methods (01.03.2017)
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Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency
Pasque, Vincent, Radzisheuskaya, Aliaksandra, Gillich, Astrid, Halley-Stott, Richard P, Panamarova, Maryna, Zernicka-Goetz, Magdalena, Surani, M Azim, Silva, José C R
Published in Journal of cell science (15.12.2012)
Published in Journal of cell science (15.12.2012)
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Reprogramming capacity of Nanog is functionally conserved in vertebrates and resides in a unique homeodomain
Theunissen, Thorold W, Costa, Yael, Radzisheuskaya, Aliaksandra, van Oosten, Anouk L, Lavial, Fabrice, Pain, Bertrand, Castro, L Filipe C, Silva, José C R
Published in Development (Cambridge) (15.11.2011)
Published in Development (Cambridge) (15.11.2011)
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NANOG-dependent function of TET1 and TET2 in establishment of pluripotency
Costa, Yael, Ding, Junjun, Theunissen, Thorold W., Faiola, Francesco, Hore, Timothy A., Shliaha, Pavel V., Fidalgo, Miguel, Saunders, Arven, Lawrence, Moyra, Dietmann, Sabine, Das, Satyabrata, Levasseur, Dana N., Li, Zhe, Xu, Mingjiang, Reik, Wolf, Silva, José C. R., Wang, Jianlong
Published in Nature (London) (21.03.2013)
Published in Nature (London) (21.03.2013)
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OCT4 induces embryonic pluripotency via STAT3 signaling and metabolic mechanisms
Stirparo, Giuliano G., Kurowski, Agata, Yanagida, Ayaka, Bates, Lawrence E., Strawbridge, Stanley E., Hladkou, Siarhei, Stuart, Hannah T., Boroviak, Thorsten E., Silva, Jose C. R., Nichols, Jennifer
Published in Proceedings of the National Academy of Sciences - PNAS (19.01.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (19.01.2021)
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Citrullination regulates pluripotency and histone H1 binding to chromatin
Christophorou, Maria A., Castelo-Branco, Gonçalo, Halley-Stott, Richard P., Oliveira, Clara Slade, Loos, Remco, Radzisheuskaya, Aliaksandra, Mowen, Kerri A., Bertone, Paul, Silva, José C. R., Zernicka-Goetz, Magdalena, Nielsen, Michael L., Gurdon, John B., Kouzarides, Tony
Published in Nature (London) (06.03.2014)
Published in Nature (London) (06.03.2014)
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A defined Oct4 level governs cell state transitions of pluripotency entry and differentiation into all embryonic lineages
Radzisheuskaya, Aliaksandra, Le Bin Chia, Gloryn, dos Santos, Rodrigo L., Theunissen, Thorold W., Castro, L. Filipe C., Nichols, Jennifer, Silva, José C. R.
Published in Nature cell biology (01.06.2013)
Published in Nature cell biology (01.06.2013)
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Long‐Term Perfusion Culture of Monoclonal Embryonic Stem Cells in 3D Hydrogel Beads for Continuous Optical Analysis of Differentiation
Kleine‐Brüggeney, Hans, van Vliet, Liisa D., Mulas, Carla, Gielen, Fabrice, Agley, Chibeza C., Silva, José C. R., Smith, Austin, Chalut, Kevin, Hollfelder, Florian
Published in Small (Weinheim an der Bergstrasse, Germany) (01.02.2019)
Published in Small (Weinheim an der Bergstrasse, Germany) (01.02.2019)
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Reprogramming human cells to naïve pluripotency: how close are we?
Bates, Lawrence E, Silva, José CR
Published in Current opinion in genetics & development (01.10.2017)
Published in Current opinion in genetics & development (01.10.2017)
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ZMYM2 inhibits NANOG-mediated reprogramming
Lawrence, Moyra, Theunissen, Thorold W, Lombard, Patrick, Adams, David J, Silva, José C R
Published in Wellcome open research (2019)
Published in Wellcome open research (2019)
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