Targeting the Prion-like Aggregation of Mutant p53 to Combat Cancer
Silva, Jerson L, Cino, Elio A, Soares, Iaci N, Ferreira, Vitor F, A. P. de Oliveira, Guilherme
Published in Accounts of chemical research (16.01.2018)
Published in Accounts of chemical research (16.01.2018)
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A hypothesis to reconcile the physical and chemical unfolding of proteins
de Oliveira, Guilherme A. P., Silva, Jerson L.
Published in Proceedings of the National Academy of Sciences - PNAS (26.05.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (26.05.2015)
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High-Pressure Chemical Biology and Biotechnology
Silva, Jerson L, Oliveira, Andrea C, Vieira, Tuane C. R. G, de Oliveira, Guilherme A. P, Suarez, Marisa C, Foguel, Debora
Published in Chemical reviews (23.07.2014)
Published in Chemical reviews (23.07.2014)
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Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues
Ferraz da Costa, Danielly C, Pereira Rangel, Luciana, Martins-Dinis, Mafalda Maria Duarte da Cunha, Ferretti, Giulia Diniz da Silva, Ferreira, Vitor F, Silva, Jerson L
Published in Molecules (Basel, Switzerland) (18.02.2020)
Published in Molecules (Basel, Switzerland) (18.02.2020)
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Bioactive Compounds and Metabolites from Grapes and Red Wine in Breast Cancer Chemoprevention and Therapy
Ferraz da Costa, Danielly C, Pereira Rangel, Luciana, Quarti, Julia, Santos, Ronimara A, Silva, Jerson L, Fialho, Eliane
Published in Molecules (Basel, Switzerland) (01.08.2020)
Published in Molecules (Basel, Switzerland) (01.08.2020)
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SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice
Fontes-Dantas, Fabricia L., Fernandes, Gabriel G., Gutman, Elisa G., De Lima, Emanuelle V., Antonio, Leticia S., Hammerle, Mariana B., Mota-Araujo, Hannah P., Colodeti, Lilian C., Araújo, Suzana M.B., Froz, Gabrielle M., da Silva, Talita N., Duarte, Larissa A., Salvio, Andreza L., Pires, Karina L., Leon, Luciane A.A., Vasconcelos, Claudia Cristina F., Romão, Luciana, Savio, Luiz Eduardo B., Silva, Jerson L., da Costa, Robson, Clarke, Julia R., Da Poian, Andrea T., Alves-Leon, Soniza V., Passos, Giselle F., Figueiredo, Claudia P.
Published in Cell reports (Cambridge) (28.03.2023)
Published in Cell reports (Cambridge) (28.03.2023)
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Phase separation of p53 precedes aggregation and is affected by oncogenic mutations and ligands
Petronilho, Elaine C, Pedrote, Murilo M, Marques, Mayra A, Passos, Yulli M, Mota, Michelle F, Jakobus, Benjamin, Sousa, Gileno dos Santos de, Pereira da Costa, Filipe, Felix, Adriani L, Ferretti, Giulia D. S, Almeida, Fernando P, Cordeiro, Yraima, Vieira, Tuane C. R. G, de Oliveira, Guilherme A. P, Silva, Jerson L
Published in Chemical science (Cambridge) (07.06.2021)
Published in Chemical science (Cambridge) (07.06.2021)
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Heparin binding confers prion stability and impairs its aggregation
Vieira, Tuane C R G, Cordeiro, Yraima, Caughey, Byron, Silva, Jerson L
Published in The FASEB journal (01.06.2014)
Published in The FASEB journal (01.06.2014)
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Loss of the p53 transactivation domain results in high amyloid aggregation of the Δ40p53 isoform in endometrial carcinoma cells
Melo dos Santos, Nataly, de Oliveira, Guilherme A.P., Ramos Rocha, Murilo, Pedrote, Murilo M., Diniz da Silva Ferretti, Giulia, Pereira Rangel, Luciana, Morgado-Diaz, José A., Silva, Jerson L., Rodrigues Pereira Gimba, Etel
Published in The Journal of biological chemistry (14.06.2019)
Published in The Journal of biological chemistry (14.06.2019)
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Anticancer Therapeutic Strategies Targeting p53 Aggregation
Ferretti, Giulia D. S., Quarti, Julia, dos Santos, Gileno, Rangel, Luciana P., Silva, Jerson L.
Published in International journal of molecular sciences (01.10.2022)
Published in International journal of molecular sciences (01.10.2022)
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Aggregation tendencies in the p53 family are modulated by backbone hydrogen bonds
Cino, Elio A, Soares, Iaci N, Pedrote, Murilo M, de Oliveira, Guilherme A P, Silva, Jerson L
Published in Scientific reports (07.09.2016)
Published in Scientific reports (07.09.2016)
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Aggregation-primed molten globule conformers of the p53 core domain provide potential tools for studying p53C aggregation in cancer
Pedrote, Murilo M., de Oliveira, Guilherme A.P., Felix, Adriani L., Mota, Michelle F., Marques, Mayra de A., Soares, Iaci N., Iqbal, Anwar, Norberto, Douglas R., Gomes, Andre M.O., Gratton, Enrico, Cino, Elio A., Silva, Jerson L.
Published in The Journal of biological chemistry (20.07.2018)
Published in The Journal of biological chemistry (20.07.2018)
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Aggregation and Prion-Like Properties of Misfolded Tumor Suppressors: Is Cancer a Prion Disease?
Costa, Danielly C F, de Oliveira, Guilherme A P, Cino, Elio A, Soares, Iaci N, Rangel, Luciana P, Silva, Jerson L
Published in Cold Spring Harbor perspectives in biology (01.10.2016)
Published in Cold Spring Harbor perspectives in biology (01.10.2016)
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The interplay between a GC-rich oligonucleotide and copper ions on prion protein conformational and phase transitions
M. Passos, Yulli, J. do Amaral, Mariana, C. Ferreira, Natalia, Macedo, Bruno, Chaves, Juliana A.P., E. de Oliveira, Vanessa, P. B. Gomes, Mariana, L. Silva, Jerson, Cordeiro, Yraima
Published in International journal of biological macromolecules (15.03.2021)
Published in International journal of biological macromolecules (15.03.2021)
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Co-localization of mutant p53 and amyloid-like protein aggregates in breast tumors
Levy, Claudia B., Stumbo, Ana C., Ano Bom, Ana P.D., Portari, Elisabeth A., Carneiro, Yraima, Silva, Jerson L., De Moura-Gallo, Claudia V.
Published in The international journal of biochemistry & cell biology (2011)
Published in The international journal of biochemistry & cell biology (2011)
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