Phospholamban antisense oligonucleotides improve cardiac function in murine cardiomyopathy
Grote Beverborg, Niels, Später, Daniela, Knöll, Ralph, Hidalgo, Alejandro, Yeh, Steve T., Elbeck, Zaher, Silljé, Herman H. W., Eijgenraam, Tim R., Siga, Humam, Zurek, Magdalena, Palmér, Malin, Pehrsson, Susanne, Albery, Tamsin, Bomer, Nils, Hoes, Martijn F., Boogerd, Cornelis J., Frisk, Michael, van Rooij, Eva, Damle, Sagar, Louch, William E., Wang, Qing-Dong, Fritsche-Danielson, Regina, Chien, Kenneth R., Hansson, Kenny M., Mullick, Adam E., de Boer, Rudolf A., van der Meer, Peter
Published in Nature communications (30.08.2021)
Published in Nature communications (30.08.2021)
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Journal Article
Polo-like kinases and the orchestration of cell division
Nigg, Erich A, Barr, Francis A, Silljé, Herman H. W
Published in Nature reviews. Molecular cell biology (01.06.2004)
Published in Nature reviews. Molecular cell biology (01.06.2004)
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Journal Article
HIPPO-Integrin-linked Kinase Cross-Talk Controls Self-Sustaining Proliferation and Survival in Pulmonary Hypertension
Kudryashova, Tatiana V, Goncharov, Dmitry A, Pena, Andressa, Kelly, Neil, Vanderpool, Rebecca, Baust, Jeff, Kobir, Ahasanul, Shufesky, William, Mora, Ana L, Morelli, Adrian E, Zhao, Jing, Ihida-Stansbury, Kaori, Chang, Baojun, DeLisser, Horace, Tuder, Rubin M, Kawut, Steven M, Silljé, Herman H W, Shapiro, Steven, Zhao, Yutong, Goncharova, Elena A
Published in American journal of respiratory and critical care medicine (01.10.2016)
Published in American journal of respiratory and critical care medicine (01.10.2016)
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Journal Article
Phosphoproteome Analysis of the Human Mitotic Spindle
Nousiainen, Marjaana, Silljé, Herman H. W., Sauer, Guido, Nigg, Erich A., Körner, Roman
Published in Proceedings of the National Academy of Sciences - PNAS (04.04.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (04.04.2006)
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A Kinase Interacting Protein 1 regulates mitochondrial protein levels in energy metabolism and promotes mitochondrial turnover after exercise
Nijholt, Kirsten T., Sánchez-Aguilera, Pablo I., Mahmoud, Belend, Gerding, Albert, Wolters, Justina C., Wolters, Anouk H. G., Giepmans, Ben N. G., Silljé, Herman H. W., de Boer, Rudolf A., Bakker, Barbara M., Westenbrink, B. Daan
Published in Scientific reports (01.11.2023)
Published in Scientific reports (01.11.2023)
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Journal Article
Inhibition of Interleukin-6 Receptor in a Murine Model of Myocardial Ischemia-Reperfusion
Hartman, Minke H T, Vreeswijk-Baudoin, Inge, Groot, Hilde E, van de Kolk, Kees W A, de Boer, Rudolf A, Mateo Leach, Irene, Vliegenthart, Rozemarijn, Sillje, Herman H W, van der Harst, Pim
Published in PloS one (09.12.2016)
Published in PloS one (09.12.2016)
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A Kinase Interacting Protein 1 (AKIP1) promotes cardiomyocyte elongation and physiological cardiac remodelling
Nijholt, Kirsten T., Sánchez-Aguilera, Pablo I., Booij, Harmen G., Oberdorf-Maass, Silke U., Dokter, Martin M., Wolters, Anouk H. G., Giepmans, Ben N. G., van Gilst, Wiek H., Brown, Joan H., de Boer, Rudolf A., Silljé, Herman H. W., Westenbrink, B. Daan
Published in Scientific reports (10.03.2023)
Published in Scientific reports (10.03.2023)
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Journal Article
Rodent heart failure models do not reflect the human circulating microRNA signature in heart failure
Vegter, Eline L, Ovchinnikova, Ekaterina S, Silljé, Herman H W, Meems, Laura M G, van der Pol, Atze, van der Velde, A Rogier, Berezikov, Eugene, Voors, Adriaan A, de Boer, Rudolf A, van der Meer, Peter
Published in PloS one (05.05.2017)
Published in PloS one (05.05.2017)
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Journal Article
The phospholamban p.(Arg14del) pathogenic variant leads to cardiomyopathy with heart failure and is unreponsive to standard heart failure therapy
Eijgenraam, Tim R, Boukens, Bastiaan J, Boogerd, Cornelis J, Schouten, E Marloes, van de Kolk, Cees W A, Stege, Nienke M, Te Rijdt, Wouter P, Hoorntje, Edgar T, van der Zwaag, Paul A, van Rooij, Eva, van Tintelen, J Peter, van den Berg, Maarten P, van der Meer, Peter, van der Velden, Jolanda, Silljé, Herman H W, de Boer, Rudolf A
Published in Scientific reports (17.06.2020)
Published in Scientific reports (17.06.2020)
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Towards a Better Understanding of Genotype-Phenotype Correlations and Therapeutic Targets for Cardiocutaneous Genes: The Importance of Functional Studies above Prediction
Vermeer, Mathilde C S C, Andrei, Daniela, Marsili, Luisa, van Tintelen, J Peter, Silljé, Herman H W, van den Berg, Maarten P, van der Meer, Peter, Bolling, Maria C
Published in International journal of molecular sciences (15.09.2022)
Published in International journal of molecular sciences (15.09.2022)
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Journal Article
Accumulation of 5-oxoproline in myocardial dysfunction and the protective effects of OPLAH
van der Pol, Atze, Gil, Andres, Silljé, Herman H W, Tromp, Jasper, Ovchinnikova, Ekaterina S, Vreeswijk-Baudoin, Inge, Hoes, Martijn, Domian, Ibrahim J, van de Sluis, Bart, van Deursen, Jan M, Voors, Adriaan A, van Veldhuisen, Dirk J, van Gilst, Wiek H, Berezikov, Eugene, van der Harst, Pim, de Boer, Rudolf A, Bischoff, Rainer, van der Meer, Peter
Published in Science translational medicine (08.11.2017)
Published in Science translational medicine (08.11.2017)
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Journal Article
Antisense Therapy Attenuates Phospholamban p.(Arg14del) Cardiomyopathy in Mice and Reverses Protein Aggregation
Eijgenraam, Tim R, Stege, Nienke M, Oliveira Nunes Teixeira, Vivian, de Brouwer, Remco, Schouten, Elisabeth M, Grote Beverborg, Niels, Sun, Liu, Später, Daniela, Knöll, Ralph, Hansson, Kenny M, Amilon, Carl, Janzén, David, Yeh, Steve T, Mullick, Adam E, van der Meer, Peter, de Boer, Rudolf A, Silljé, Herman H W
Published in International journal of molecular sciences (22.02.2022)
Published in International journal of molecular sciences (22.02.2022)
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Journal Article
Metabolic Remodeling in the Pressure-Loaded Right Ventricle: Shifts in Glucose and Fatty Acid Metabolism-A Systematic Review and Meta-Analysis
Koop, Anne-Marie C, Bossers, Guido P L, Ploegstra, Mark-Jan, Hagdorn, Quint A J, Berger, Rolf M F, Silljé, Herman H W, Bartelds, Beatrijs
Published in Journal of the American Heart Association (05.11.2019)
Published in Journal of the American Heart Association (05.11.2019)
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Journal Article
Loss of mitochondrial exo/endonuclease EXOG affects mitochondrial respiration and induces ROS-mediated cardiomyocyte hypertrophy
Tigchelaar, Wardit, Yu, Hongjuan, de Jong, Anne Margreet, van Gilst, Wiek H, van der Harst, Pim, Westenbrink, B Daan, de Boer, Rudolf A, Silljé, Herman H W
Published in American Journal of Physiology: Cell Physiology (15.01.2015)
Published in American Journal of Physiology: Cell Physiology (15.01.2015)
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LXRα improves myocardial glucose tolerance and reduces cardiac hypertrophy in a mouse model of obesity-induced type 2 diabetes
Cannon, Megan V., Silljé, Herman H. W., Sijbesma, Jürgen W. A., Khan, Mohsin A. F., Steffensen, Knut R., van Gilst, Wiek H., de Boer, Rudolf A.
Published in Diabetologia (01.03.2016)
Published in Diabetologia (01.03.2016)
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Functional investigation of two simultaneous or separately segregating DSP variants within a single family supports the theory of a dose‐dependent disease severity
Vermeer, Mathilde C. S. C., Andrei, Daniela, Kramer, Duco, Nijenhuis, Albertine M., Hoedemaekers, Yvonne M., Westers, Helga, Jongbloed, Jan D. H., Pas, Hendri H., Berg, Maarten P., Silljé, Herman H. W., Meer, Peter, Bolling, Maria C.
Published in Experimental dermatology (01.06.2022)
Published in Experimental dermatology (01.06.2022)
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Journal Article
Cardiac function and architecture are maintained in a model of cardiorestricted overexpression of the prorenin-renin receptor
Mahmud, Hasan, Candido, Wellington Mardoqueu, van Genne, Linda, Vreeswijk-Baudoin, Inge, Yu, Hongjuan, van de Sluis, Bart, van Deursen, Jan, van Gilst, Wiek H, Silljé, Herman H W, de Boer, Rudolf A
Published in PloS one (25.02.2014)
Published in PloS one (25.02.2014)
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Journal Article
A translation re‐initiation variant in KLHL24 also causes epidermolysis bullosa simplex and dilated cardiomyopathy via intermediate filament degradation
Vermeer, Mathilde C.S.C., Al‐Shinnag, Mohammad, Silljé, Herman H.W., Gaytan, Antonio Esquivel, Murrell, Dedee F., McGaughran, Julie, Melbourne, Wei, Cowan, Timothy, Akker, Peter C., Spaendonck‐Zwarts, Karin Y., Meer, Peter, Bolling, Maria C.
Published in British journal of dermatology (1951) (01.12.2022)
Published in British journal of dermatology (1951) (01.12.2022)
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