Parvalbumin overexpression alters immune-mediated increases in intracellular calcium, and delays disease onset in a transgenic model of familial amyotrophic lateral sclerosis
Beers, D. R., Ho, B. K., Siklos, L., Alexianu, M. E., Mosier, D. R., Mohamed, A. H., Otsuka, Y., Kozovska, M. E., McAlhany, R. E., Smith, R. G., Appel, S. H.
Published in Journal of neurochemistry (01.11.2001)
Published in Journal of neurochemistry (01.11.2001)
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ApoE-Targeting Increases the Transfer of Solid Lipid Nanoparticles with Donepezil Cargo across a Culture Model of the Blood-Brain Barrier
Topal, Gizem Rüya, Mészáros, Mária, Porkoláb, Gergő, Szecskó, Anikó, Polgár, Tamás Ferenc, Siklós, László, Deli, Mária A, Veszelka, Szilvia, Bozkir, Asuman
Published in Pharmaceutics (29.12.2020)
Published in Pharmaceutics (29.12.2020)
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Motoneuronal inflammasome activation triggers excessive neuroinflammation and impedes regeneration after sciatic nerve injury
Molnár, Kinga, Nógrádi, Bernát, Kristóf, Rebeka, Mészáros, Ádám, Pajer, Krisztián, Siklós, László, Nógrádi, Antal, Wilhelm, Imola, Krizbai, István A
Published in Journal of neuroinflammation (19.03.2022)
Published in Journal of neuroinflammation (19.03.2022)
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Wild-Type Microglia Extend Survival in PU.1 Knockout Mice with Familial Amyotrophic Lateral Sclerosis
Beers, David R., Henkel, Jenny S., Xiao, Qin, Zhao, Weihua, Wang, Jinghong, Yen, Albert A., Siklos, Laszlo, McKercher, Scott R., Appel, Stanley H.
Published in Proceedings of the National Academy of Sciences - PNAS (24.10.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (24.10.2006)
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Passive Transfer of Blood Sera from ALS Patients with Identified Mutations Results in Elevated Motoneuronal Calcium Level and Loss of Motor Neurons in the Spinal Cord of Mice
Polgár, Tamás F., Meszlényi, Valéria, Nógrádi, Bernát, Körmöczy, Laura, Spisák, Krisztina, Tripolszki, Kornélia, Széll, Márta, Obál, Izabella, Engelhardt, József I., Siklós, László, Patai, Roland
Published in International journal of molecular sciences (16.09.2021)
Published in International journal of molecular sciences (16.09.2021)
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Experimental Motor Neuron Disease Induced in Mice with Long-Term Repeated Intraperitoneal Injections of Serum from ALS Patients
Obál, Izabella, Nógrádi, Bernát, Meszlényi, Valéria, Patai, Roland, Ricken, Gerda, Kovacs, Gabor G, Tripolszki, Kornélia, Széll, Márta, Siklós, László, Engelhardt, József I
Published in International journal of molecular sciences (25.05.2019)
Published in International journal of molecular sciences (25.05.2019)
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Transmigration of melanoma cells through the blood-brain barrier: role of endothelial tight junctions and melanoma-released serine proteases
Fazakas, Csilla, Wilhelm, Imola, Nagyoszi, Péter, Farkas, Attila E, Haskó, János, Molnár, Judit, Bauer, Hannelore, Bauer, Hans-Christian, Ayaydin, Ferhan, Dung, Ngo Thi Khue, Siklós, László, Krizbai, István A
Published in PloS one (02.06.2011)
Published in PloS one (02.06.2011)
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Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue
Henkel, Jenny S., Engelhardt, Joseph I., Siklós, László, Simpson, Ericka P., Kim, Seung H., Pan, Tianhong, Goodman, J. Clay, Siddique, Teepu, Beers, David R., Appel, Stanley H.
Published in Annals of neurology (01.02.2004)
Published in Annals of neurology (01.02.2004)
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Passive Transfer of Sera from ALS Patients with Identified Mutations Evokes an Increased Synaptic Vesicle Number and Elevation of Calcium Levels in Motor Axon Terminals, Similar to Sera from Sporadic Patients
Meszlényi, Valéria, Patai, Roland, Polgár, Tamás F, Nógrádi, Bernát, Körmöczy, Laura, Kristóf, Rebeka, Spisák, Krisztina, Tripolszki, Kornélia, Széll, Márta, Obál, Izabella, Engelhardt, József I, Siklós, László
Published in International journal of molecular sciences (03.08.2020)
Published in International journal of molecular sciences (03.08.2020)
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Upregulation of Nucleotide-Binding Oligomerization Domain-, LRR- and Pyrin Domain-Containing Protein 3 in Motoneurons Following Peripheral Nerve Injury in Mice
Nógrádi, Bernát, Nyúl-Tóth, Ádám, Kozma, Mihály, Molnár, Kinga, Patai, Roland, Siklós, László, Wilhelm, Imola, Krizbai, István A
Published in Frontiers in pharmacology (26.11.2020)
Published in Frontiers in pharmacology (26.11.2020)
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Niosomes decorated with dual ligands targeting brain endothelial transporters increase cargo penetration across the blood-brain barrier
Mészáros, Mária, Porkoláb, Gergő, Kiss, Lóránd, Pilbat, Ana-Maria, Kóta, Zoltán, Kupihár, Zoltán, Kéri, Albert, Galbács, Gábor, Siklós, László, Tóth, András, Fülöp, Lívia, Csete, Mária, Sipos, Áron, Hülper, Petra, Sipos, Péter, Páli, Tibor, Rákhely, Gábor, Szabó-Révész, Piroska, Deli, Mária A, Veszelka, Szilvia
Published in European journal of pharmaceutical sciences (15.10.2018)
Published in European journal of pharmaceutical sciences (15.10.2018)
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An MND/ALS phenotype associated with C9orf72 repeat expansion: Abundant p62-positive, TDP-43-negative inclusions in cerebral cortex, hippocampus and cerebellum but without associated cognitive decline
Troakes, Claire, Maekawa, Satomi, Wijesekera, Lokesh, Rogelj, Boris, Siklós, László, Bell, Christopher, Smith, Bradley, Newhouse, Stephen, Vance, Caroline, Johnson, Lauren, Hortobágyi, Tibor, Shatunov, Aleksey, Al-Chalabi, Ammar, Leigh, Nigel, Shaw, Christopher E., King, Andrew, Al-Sarraj, Safa
Published in Neuropathology (01.10.2012)
Published in Neuropathology (01.10.2012)
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Examination of the Role of Mitochondrial Morphology and Function in the Cardioprotective Effect of Sodium Nitrite Administered 24 h Before Ischemia/Reperfusion Injury
Demeter-Haludka, Vivien, Kovács, Mária, Petrus, Alexandra, Patai, Roland, Muntean, Danina M, Siklós, László, Végh, Ágnes
Published in Frontiers in pharmacology (28.03.2018)
Published in Frontiers in pharmacology (28.03.2018)
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Highly immunoreactive IgG antibodies directed against a set of twenty human proteins in the sera of patients with amyotrophic lateral sclerosis identified by protein array
May, Caroline, Nordhoff, Eckhard, Casjens, Swaantje, Turewicz, Michael, Eisenacher, Martin, Gold, Ralf, Brüning, Thomas, Pesch, Beate, Stephan, Christian, Woitalla, Dirk, Penke, Botond, Janáky, Tamás, Virók, Dezső, Siklós, László, Engelhardt, Jozsef I, Meyer, Helmut E
Published in PloS one (26.02.2014)
Published in PloS one (26.02.2014)
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Axotomy Leads to Reduced Calcium Increase and Earlier Termination of CCL2 Release in Spinal Motoneurons with Upregulated Parvalbumin Followed by Decreased Neighboring Microglial Activation
Paizs, Melinda, Patai, Roland, Engelhardt, Jozsef I, Katarova, Zoya, Obal, Izabella, Siklos, Laszlo
Published in CNS & neurological disorders drug targets (01.01.2017)
Published in CNS & neurological disorders drug targets (01.01.2017)
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Presymptomatically applied AMPA receptor antagonist prevents calcium increase in vulnerable type of motor axon terminals of mice modeling amyotrophic lateral sclerosis
Patai, Roland, Paizs, Melinda, Tortarolo, Massimo, Bendotti, Caterina, Obál, Izabella, Engelhardt, József I., Siklós, László
Published in Biochimica et biophysica acta. Molecular basis of disease (01.07.2017)
Published in Biochimica et biophysica acta. Molecular basis of disease (01.07.2017)
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Intraperitoneally administered IgG from patients with amyotrophic lateral sclerosis or from an immune-mediated goat model increase the levels of TNF-α, IL-6, and IL-10 in the spinal cord and serum of mice
Obál, Izabella, Klausz, Gergely, Mándi, Yvette, Deli, Mária, Siklós, László, Engelhardt, József I
Published in Journal of neuroinflammation (24.05.2016)
Published in Journal of neuroinflammation (24.05.2016)
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Aromatase and estrogen receptor beta expression in the rat olfactory bulb: Neuroestrogen action in the first relay station of the olfactory pathway?
Hoyk, Zsofia, Csakvari, Eszter, Gyenes, Andrea, Siklos, Laszlo, Harada, Nobuhiro, Parducz, Arpad
Published in Acta neurobiologiae experimentalis (01.01.2014)
Published in Acta neurobiologiae experimentalis (01.01.2014)
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