Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathogenesis
Olafsdottir, Thorunn A., Theodors, Fannar, Bjarnadottir, Kristbjorg, Bjornsdottir, Unnur Steina, Agustsdottir, Arna B., Stefansson, Olafur A., Ivarsdottir, Erna V., Sigurdsson, Jon K., Benonisdottir, Stefania, Eyjolfsson, Gudmundur I., Gislason, David, Gislason, Thorarinn, Guðmundsdóttir, Steinunn, Gylfason, Arnaldur, Halldorsson, Bjarni V., Halldorsson, Gisli H., Juliusdottir, Thorhildur, Kristinsdottir, Anna M., Ludviksdottir, Dora, Ludviksson, Bjorn R., Masson, Gisli, Norland, Kristjan, Onundarson, Pall T., Olafsson, Isleifur, Sigurdardottir, Olof, Stefansdottir, Lilja, Sveinbjornsson, Gardar, Tragante, Vinicius, Gudbjartsson, Daniel F., Thorleifsson, Gudmar, Sulem, Patrick, Thorsteinsdottir, Unnur, Norddahl, Gudmundur L., Jonsdottir, Ingileif, Stefansson, Kari
Published in Nature communications (20.01.2020)
Published in Nature communications (20.01.2020)
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A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis
Kristjansson, Ragnar P., Benonisdottir, Stefania, Davidsson, Olafur B., Oddsson, Asmundur, Tragante, Vinicius, Sigurdsson, Jon K., Stefansdottir, Lilja, Jonsson, Stefan, Jensson, Brynjar O., Arthur, Joseph G., Arnadottir, Gudny A., Sulem, Gerald, Halldorsson, Bjarni V., Gunnarsson, Bjarni, Halldorsson, Gisli H., Stefansson, Olafur A., Oskarsson, Gudjon R., Deaton, Aimee M., Olafsson, Isleifur, Eyjolfsson, Gudmundur I., Sigurdardottir, Olof, Onundarson, Pall T., Gislason, David, Gislason, Thorarinn, Ludviksson, Bjorn R., Ludviksdottir, Dora, Olafsdottir, Thorunn A., Rafnar, Thorunn, Masson, Gisli, Zink, Florian, Bjornsdottir, Gyda, Magnusson, Olafur Th, Bjornsdottir, Unnur S., Thorleifsson, Gudmar, Norddahl, Gudmundur L., Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Jonsdottir, Ingileif, Sulem, Patrick, Stefansson, Kari
Published in Nature genetics (01.02.2019)
Published in Nature genetics (01.02.2019)
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A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma
Smith, Dirk, Helgason, Hannes, Sulem, Patrick, Bjornsdottir, Unnur Steina, Lim, Ai Ching, Sveinbjornsson, Gardar, Hasegawa, Haruki, Brown, Michael, Ketchem, Randal R, Gavala, Monica, Garrett, Logan, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Magnusson, Olafur T, Eyjolfsson, Gudmundur I, Olafsson, Isleifur, Onundarson, Pall Torfi, Sigurdardottir, Olof, Gislason, David, Gislason, Thorarinn, Ludviksson, Bjorn Runar, Ludviksdottir, Dora, Boezen, H Marike, Heinzmann, Andrea, Krueger, Marcus, Porsbjerg, Celeste, Ahluwalia, Tarunveer S, Waage, Johannes, Backer, Vibeke, Deichmann, Klaus A, Koppelman, Gerard H, Bønnelykke, Klaus, Bisgaard, Hans, Masson, Gisli, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F, Johnston, James A, Jonsdottir, Ingileif, Stefansson, Kari
Published in PLoS genetics (08.03.2017)
Published in PLoS genetics (08.03.2017)
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Identification of Common Genetic Variants Influencing Spontaneous Dizygotic Twinning and Female Fertility
Mbarek, Hamdi, Steinberg, Stacy, Nyholt, Dale R., Gordon, Scott D., Miller, Michael B., McRae, Allan F., Hottenga, Jouke Jan, Day, Felix R., Willemsen, Gonneke, de Geus, Eco J., Davies, Gareth E., Martin, Hilary C., Penninx, Brenda W., Jansen, Rick, McAloney, Kerrie, Vink, Jacqueline M., Kaprio, Jaakko, Plomin, Robert, Spector, Tim D., Magnusson, Patrik K., Reversade, Bruno, Harris, R. Alan, Aagaard, Kjersti, Kristjansson, Ragnar P., Olafsson, Isleifur, Eyjolfsson, Gudmundur Ingi, Sigurdardottir, Olof, Iacono, William G., Lambalk, Cornelis B., Montgomery, Grant W., McGue, Matt, Ong, Ken K., Perry, John R.B., Martin, Nicholas G., Stefánsson, Hreinn, Stefánsson, Kari, Boomsma, Dorret I.
Published in American journal of human genetics (05.05.2016)
Published in American journal of human genetics (05.05.2016)
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Variability of Pasteurella multocida isolated from Icelandic sheep and detection of the toxA gene
Einarsdottir, Thorbjorg, Gunnarsson, Eggert, Sigurdardottir, Olof G, Jorundsson, Einar, Fridriksdottir, Vala, Thorarinsdottir, Gudridur E, Hjartardottir, Sigridur
Published in Journal of medical microbiology (01.09.2016)
Published in Journal of medical microbiology (01.09.2016)
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Skin-infiltrating T cells and cytokine expression in Icelandic horses affected with insect bite hypersensitivity: A possible role for regulatory T cells
Heimann, Mareike, Janda, Jozef, Sigurdardottir, Olöf G., Svansson, Vilhjalmur, Klukowska, Jolanta, von Tscharner, Claudia, Doherr, Marcus, Broström, Hans, Andersson, Lisa S., Einarsson, Sigurjón, Marti, Eliane, Torsteinsdottir, Sigurbjörg
Published in Veterinary immunology and immunopathology (15.03.2011)
Published in Veterinary immunology and immunopathology (15.03.2011)
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A Splice Region Variant in LDLR Lowers Non-high Density Lipoprotein Cholesterol and Protects against Coronary Artery Disease
Gretarsdottir, Solveig, Helgason, Hannes, Helgadottir, Anna, Sigurdsson, Asgeir, Thorleifsson, Gudmar, Magnusdottir, Audur, Oddsson, Asmundur, Steinthorsdottir, Valgerdur, Rafnar, Thorunn, de Graaf, Jacqueline, Daneshpour, Maryam S, Hedayati, Mehdi, Azizi, Fereidoun, Grarup, Niels, Jørgensen, Torben, Vestergaard, Henrik, Hansen, Torben, Eyjolfsson, Gudmundur, Sigurdardottir, Olof, Olafsson, Isleifur, Kiemeney, Lambertus A, Pedersen, Oluf, Sulem, Patrick, Thorgeirsson, Gudmundur, Gudbjartsson, Daniel F, Holm, Hilma, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in PLoS genetics (01.09.2015)
Published in PLoS genetics (01.09.2015)
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Genetic variants associated with platelet count are predictive of human disease and physiological markers
Mikaelsdottir, Evgenia, Thorleifsson, Gudmar, Stefansdottir, Lilja, Halldorsson, Gisli, Sigurdsson, Jon K., Lund, Sigrun H., Tragante, Vinicius, Melsted, Pall, Rognvaldsson, Solvi, Norland, Kristjan, Helgadottir, Anna, Magnusson, Magnus K., Ragnarsson, Gunnar B., Kristinsson, Sigurdur Y., Reykdal, Sigrun, Vidarsson, Brynjar, Gudmundsdottir, Ingibjorg J., Olafsson, Isleifur, Onundarson, Pall T., Sigurdardottir, Olof, Sigurdsson, Emil L., Grondal, Gerdur, Geirsson, Arni J., Geirsson, Gudmundur, Gudmundsson, Julius, Holm, Hilma, Saevarsdottir, Saedis, Jonsdottir, Ingileif, Thorgeirsson, Gudmundur, Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Rafnar, Thorunn, Stefansson, Kari
Published in Communications biology (27.09.2021)
Published in Communications biology (27.09.2021)
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Mycoplasma ovipneumoniae--a primary cause of severe pneumonia epizootics in the Norwegian Muskox (Ovibos moschatus) population
Handeland, Kjell, Tengs, Torstein, Kokotovic, Branko, Vikøren, Turid, Ayling, Roger D, Bergsjø, Bjarne, Sigurðardóttir, Olöf G, Bretten, Tord
Published in PloS one (08.09.2014)
Published in PloS one (08.09.2014)
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Genomic Dissection of an Icelandic Epidemic of Respiratory Disease in Horses and Associated Zoonotic Cases
Björnsdóttir, Sigríður, Harris, Simon R, Svansson, Vilhjálmur, Gunnarsson, Eggert, Sigurðardóttir, Ólöf G, Gammeljord, Kristina, Steward, Karen F, Newton, J Richard, Robinson, Carl, Charbonneau, Amelia R L, Parkhill, Julian, Holden, Matthew T G, Waller, Andrew S
Published in mBio (01.08.2017)
Published in mBio (01.08.2017)
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Long-read sequencing of 3,622 Icelanders provides insight into the role of structural variants in human diseases and other traits
Beyter, Doruk, Ingimundardottir, Helga, Oddsson, Asmundur, Eggertsson, Hannes P., Bjornsson, Eythor, Jonsson, Hakon, Atlason, Bjarni A., Kristmundsdottir, Snaedis, Mehringer, Svenja, Hardarson, Marteinn T., Gudjonsson, Sigurjon A., Magnusdottir, Droplaug N., Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Kristjansson, Ragnar P., Sverrisson, Sverrir T., Holley, Guillaume, Palsson, Gunnar, Stefansson, Olafur A., Eyjolfsson, Gudmundur, Olafsson, Isleifur, Sigurdardottir, Olof, Torfason, Bjarni, Masson, Gisli, Helgason, Agnar, Thorsteinsdottir, Unnur, Holm, Hilma, Gudbjartsson, Daniel F., Sulem, Patrick, Magnusson, Olafur T., Halldorsson, Bjarni V., Stefansson, Kari
Published in Nature genetics (01.06.2021)
Published in Nature genetics (01.06.2021)
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Journal Article
Large-scale whole-genome sequencing of the Icelandic population
Gudbjartsson, Daniel F, Helgason, Hannes, Gudjonsson, Sigurjon A, Zink, Florian, Oddson, Asmundur, Gylfason, Arnaldur, Besenbacher, Soren, Magnusson, Gisli, Halldorsson, Bjarni V, Hjartarson, Eirikur, Sigurdsson, Gunnar Th, Stacey, Simon N, Frigge, Michael L, Holm, Hilma, Saemundsdottir, Jona, Helgadottir, Hafdis Th, Johannsdottir, Hrefna, Sigfusson, Gunnlaugur, Thorgeirsson, Gudmundur, Sverrisson, Jon Th, Gretarsdottir, Solveig, Walters, G Bragi, Rafnar, Thorunn, Thjodleifsson, Bjarni, Bjornsson, Einar S, Olafsson, Sigurdur, Thorarinsdottir, Hildur, Steingrimsdottir, Thora, Gudmundsdottir, Thora S, Theodors, Asgeir, Jonasson, Jon G, Sigurdsson, Asgeir, Bjornsdottir, Gyda, Jonsson, Jon J, Thorarensen, Olafur, Ludvigsson, Petur, Gudbjartsson, Hakon, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Olafsson, Isleifur, Arnar, David O, Magnusson, Olafur Th, Kong, Augustine, Masson, Gisli, Thorsteinsdottir, Unnur, Helgason, Agnar, Sulem, Patrick, Stefansson, Kari
Published in Nature genetics (01.05.2015)
Published in Nature genetics (01.05.2015)
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Journal Article
Variants with large effects on blood lipids and the role of cholesterol and triglycerides in coronary disease
Helgadottir, Anna, Gretarsdottir, Solveig, Thorleifsson, Gudmar, Hjartarson, Eirikur, Sigurdsson, Asgeir, Magnusdottir, Audur, Jonasdottir, Aslaug, Kristjansson, Helgi, Sulem, Patrick, Oddsson, Asmundur, Sveinbjornsson, Gardar, Steinthorsdottir, Valgerdur, Rafnar, Thorunn, Masson, Gisli, Jonsdottir, Ingileif, Olafsson, Isleifur, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Daneshpour, Maryam S, Khalili, Davood, Azizi, Fereidoun, Swinkels, Dorine W, Kiemeney, Lambertus, Quyyumi, Arshed A, Levey, Allan I, Patel, Riyaz S, Hayek, Salim S, Gudmundsdottir, Ingibjorg J, Thorgeirsson, Gudmundur, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F, Holm, Hilma, Stefansson, Kari
Published in Nature genetics (01.06.2016)
Published in Nature genetics (01.06.2016)
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Fatal infection in two Icelandic stallions caused by Halicephalobus gingivalis (Nematoda: Rhabditida)
Eydal, Matthías, Bambir, Slavko H., Sigurdarson, Sigurdur, Gunnarsson, Eggert, Svansson, Vilhjámur, Fridriksson, Stefán, Benediktsson, Ellert Thór, Sigurdardóttir, Ólöf G.
Published in Veterinary parasitology (25.05.2012)
Published in Veterinary parasitology (25.05.2012)
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Journal Article
Common and rare variants associated with kidney stones and biochemical traits
Oddsson, Asmundur, Sulem, Patrick, Helgason, Hannes, Edvardsson, Vidar O., Thorleifsson, Gudmar, Sveinbjörnsson, Gardar, Haraldsdottir, Eik, Eyjolfsson, Gudmundur I., Sigurdardottir, Olof, Olafsson, Isleifur, Masson, Gisli, Holm, Hilma, Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Indridason, Olafur S., Palsson, Runolfur, Stefansson, Kari
Published in Nature communications (14.08.2015)
Published in Nature communications (14.08.2015)
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Journal Article
Insights into imprinting from parent-of-origin phased methylomes and transcriptomes
Zink, Florian, Magnusdottir, Droplaug N., Magnusson, Olafur T., Walker, Nicolas J., Morris, Tiffany J., Sigurdsson, Asgeir, Halldorsson, Gisli H., Gudjonsson, Sigurjon A., Melsted, Pall, Ingimundardottir, Helga, Kristmundsdottir, Snædis, Alexandersson, Kristjan F., Helgadottir, Anna, Gudmundsson, Julius, Rafnar, Thorunn, Jonsdottir, Ingileif, Holm, Hilma, Eyjolfsson, Gudmundur Ingi, Sigurdardottir, Olof, Olafsson, Isleifur, Masson, Gisli, Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Halldorsson, Bjarni V., Stacey, Simon N., Stefansson, Kari
Published in Nature genetics (01.11.2018)
Published in Nature genetics (01.11.2018)
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Journal Article
Rare SCARB1 mutations associate with high-density lipoprotein cholesterol but not with coronary artery disease
Helgadottir, Anna, Sulem, Patrick, Thorgeirsson, Gudmundur, Gretarsdottir, Solveig, Thorleifsson, Gudmar, Jensson, Brynjar Ö, Arnadottir, Gudny A, Olafsson, Isleifur, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F, Holm, Hilma, Stefansson, Kari
Published in European heart journal (14.06.2018)
Published in European heart journal (14.06.2018)
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Journal Article
Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease
Nioi, Paul, Sigurdsson, Asgeir, Thorleifsson, Gudmar, Helgason, Hannes, Agustsdottir, Arna B, Norddahl, Gudmundur L, Helgadottir, Anna, Magnusdottir, Audur, Jonasdottir, Aslaug, Gretarsdottir, Solveig, Jonsdottir, Ingileif, Steinthorsdottir, Valgerdur, Rafnar, Thorunn, Swinkels, Dorine W, Galesloot, Tessel E, Grarup, Niels, Jørgensen, Torben, Vestergaard, Henrik, Hansen, Torben, Lauritzen, Torsten, Linneberg, Allan, Friedrich, Nele, Krarup, Nikolaj T, Fenger, Mogens, Abildgaard, Ulrik, Hansen, Peter R, Galløe, Anders M, Braund, Peter S, Nelson, Christopher P, Hall, Alistair S, Williams, Michael J.A, van Rij, Andre M, Jones, Gregory T, Patel, Riyaz S, Levey, Allan I, Hayek, Salim, Shah, Svati H, Reilly, Muredach, Eyjolfsson, Gudmundur I, Sigurdardottir, Olof, Olafsson, Isleifur, Kiemeney, Lambertus A, Quyyumi, Arshed A, Rader, Daniel J, Kraus, William E, Samani, Nilesh J, Pedersen, Oluf, Thorgeirsson, Gudmundur, Masson, Gisli, Holm, Hilma, Gudbjartsson, Daniel, Sulem, Patrick, Thorsteinsdottir, Unnur, Stefansson, Kari
Published in The New England journal of medicine (02.06.2016)
Published in The New England journal of medicine (02.06.2016)
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Identification of sequence variants influencing immunoglobulin levels
Jonsson, Stefan, Sveinbjornsson, Gardar, de Lapuente Portilla, Aitzkoa Lopez, Swaminathan, Bhairavi, Plomp, Rosina, Dekkers, Gillian, Ajore, Ram, Ali, Mina, Bentlage, Arthur E H, Elmér, Evelina, Eyjolfsson, Gudmundur I, Gudjonsson, Sigurjon A, Gullberg, Urban, Gylfason, Arnaldur, Halldorsson, Bjarni V, Hansson, Markus, Holm, Hilma, Johansson, Åsa, Johnsson, Ellinor, Jonasdottir, Aslaug, Ludviksson, Bjorn R, Oddsson, Asmundur, Olafsson, Isleifur, Olafsson, Sigurgeir, Sigurdardottir, Olof, Sigurdsson, Asgeir, Stefansdottir, Lilja, Masson, Gisli, Sulem, Patrick, Wuhrer, Manfred, Wihlborg, Anna-Karin, Thorleifsson, Gudmar, Gudbjartsson, Daniel F, Thorsteinsdottir, Unnur, Vidarsson, Gestur, Jonsdottir, Ingileif, Nilsson, Björn, Stefansson, Kari
Published in Nature genetics (01.08.2017)
Published in Nature genetics (01.08.2017)
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