Cross‐linked polysiloxane‐coated stable bond O‐9‐(2,6‐diisopropylphenylcarbamoyl)quinine and quinidine chiral stationary phases as well as application in enantioselective cryo‐HPLC
Woiwode, Ulrich, Sievers‐Engler, Adrian, Lämmerhofer, Michael
Published in Electrophoresis (01.06.2024)
Published in Electrophoresis (01.06.2024)
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Journal Article
Targeted ultra-high performance liquid chromatography-tandem mass spectrometry assay for the quantification of medium-chain phosphatidylcholines in platelets of coronary artery disease patients
Janker, Tamara, Brun, Adrian, Sievers-Engler, Adrian, Dittrich, Kristina, Gawaz, Meinrad, Lämmerhofer, Michael
Published in Journal of Chromatography Open (01.11.2024)
Published in Journal of Chromatography Open (01.11.2024)
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Journal Article
Methods for the comprehensive structural elucidation of constitution and stereochemistry of lipopeptides
Gerhardt, Heike, Sievers-Engler, Adrian, Jahanshah, Ghazaleh, Pataj, Zoltán, Ianni, Federica, Gross, Harald, Lindner, Wolfgang, Lämmerhofer, Michael
Published in Journal of Chromatography A (08.01.2016)
Published in Journal of Chromatography A (08.01.2016)
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Journal Article
Wide-pore fully porous mixed-mode octyl/pyridyl-bonded silica material with pH-dependent surface charge reversal for high-performance hydrophobic charge-induction chromatography of proteins
Wolter, Marc, Barth, Christoph, Maalouf, Mirna, Kramer, Markus, Sievers-Engler, Adrian, Lämmerhofer, Michael
Published in Journal of Chromatography A (22.11.2024)
Published in Journal of Chromatography A (22.11.2024)
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Journal Article
Determination of double bond positions in unsaturated fatty acids by pre-column derivatization with dimethyl and dipyridyl disulfide followed by LC-SWATH-MS analysis
Olfert, Matthias, Knappe, Cornelius, Sievers-Engler, Adrian, Masberg, Benedikt, Lämmerhofer, Michael
Published in Analytical and bioanalytical chemistry (05.10.2024)
Published in Analytical and bioanalytical chemistry (05.10.2024)
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Journal Article
Automated sample preparation with 6-Aminoquinolyl-N-hydroxysuccinimidyl carbamate and iodoacetamide derivatization reagents for enantioselective liquid chromatography tandem mass spectrometry amino acid analysis
Li, Feiyang, Karongo, Ryan, Mavridou, Despoina, Horak, Jeannie, Sievers-Engler, Adrian, Lämmerhofer, Michael
Published in Journal of Chromatography A (11.10.2023)
Published in Journal of Chromatography A (11.10.2023)
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Journal Article
Trisubstituted Imidazoles with a Rigidized Hinge Binding Motif Act As Single Digit nM Inhibitors of Clinically Relevant EGFR L858R/T790M and L858R/T790M/C797S Mutants: An Example of Target Hopping
Juchum, Michael, Günther, Marcel, Döring, Eva, Sievers-Engler, Adrian, Lämmerhofer, Michael, Laufer, Stefan
Published in Journal of medicinal chemistry (08.06.2017)
Published in Journal of medicinal chemistry (08.06.2017)
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Journal Article
UHPLC-ESI-MS/MS assay for quantification of endocannabinoids in cerebrospinal fluid using surrogate calibrant and surrogate matrix approaches
Aydin, Ece, Cebo, Malgorzata, Mielnik, Justyna, Richter, Hardy, Schüle, Rebecca, Sievers-Engler, Adrian, Młynarz, Piotr, Lämmerhofer, Michael
Published in Journal of pharmaceutical and biomedical analysis (05.01.2023)
Published in Journal of pharmaceutical and biomedical analysis (05.01.2023)
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Journal Article
Preparation of fluorescent labeled gentamicin as biological tracer and its characterization by liquid chromatography and high resolution mass spectrometry
Woiwode, Ulrich, Sievers-Engler, Adrian, Lämmerhofer, Michael
Published in Journal of pharmaceutical and biomedical analysis (20.03.2016)
Published in Journal of pharmaceutical and biomedical analysis (20.03.2016)
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Journal Article
Targeting the Gatekeeper MET146 of C‑Jun N‑Terminal Kinase 3 Induces a Bivalent Halogen/Chalcogen Bond
Lange, Andreas, Günther, Marcel, Büttner, Felix Michael, Zimmermann, Markus O, Heidrich, Johannes, Hennig, Susanne, Zahn, Stefan, Schall, Christoph, Sievers-Engler, Adrian, Ansideri, Francesco, Koch, Pierre, Laemmerhofer, Michael, Stehle, Thilo, Laufer, Stefan A, Boeckler, Frank M
Published in Journal of the American Chemical Society (25.11.2015)
Published in Journal of the American Chemical Society (25.11.2015)
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Journal Article
Tri- and Tetrasubstituted Pyridinylimidazoles as Covalent Inhibitors of c‑Jun N‑Terminal Kinase 3
Muth, Felix, El-Gokha, Ahmed, Ansideri, Francesco, Eitel, Michael, Döring, Eva, Sievers-Engler, Adrian, Lange, Andreas, Boeckler, Frank M, Lämmerhofer, Michael, Koch, Pierre, Laufer, Stefan A
Published in Journal of medicinal chemistry (26.01.2017)
Published in Journal of medicinal chemistry (26.01.2017)
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Journal Article
Design, Synthesis, and Biological Evaluation of Novel Type l1/2 p38 alpha MAP Kinase Inhibitors with Excellent Selectivity, High Potency, and Prolonged Target Residence Time by Interfering with the R-Spine
Walter, Niklas M., Wentsch, Heike K., Buehrmann, Mike, Bauer, Silke M., Doering, Eva, Mayer-Wrangowski, Svenja, Sievers-Engler, Adrian, Willemsen-Seegers, Nicole, Zaman, Guido, Buijsman, Rogier, Laemmerhofer, Michael, Rauh, Daniel, Laufer, Stefan A.
Published in Journal of medicinal chemistry (12.10.2017)
Published in Journal of medicinal chemistry (12.10.2017)
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Journal Article
Surface-anchored counterions on weak chiral anion-exchangers accelerate separations and improve their compatibility for mass-spectrometry-hyphenation
Woiwode, Ulrich, Sievers-Engler, Adrian, Zimmermann, Aleksandra, Lindner, Wolfgang, Sánchez-Muñoz, Orlando L., Lämmerhofer, Michael
Published in Journal of Chromatography A (23.06.2017)
Published in Journal of Chromatography A (23.06.2017)
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Journal Article
Ligand–receptor binding increments in enantioselective liquid chromatography
Sievers-Engler, Adrian, Lindner, Wolfgang, Lämmerhofer, Michael
Published in Journal of Chromatography A (10.10.2014)
Published in Journal of Chromatography A (10.10.2014)
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Journal Article