Precision oncology in metastatic colorectal cancer — from biology to medicine
Di Nicolantonio, Federica, Vitiello, Pietro Paolo, Marsoni, Silvia, Siena, Salvatore, Tabernero, Josep, Trusolino, Livio, Bernards, Rene, Bardelli, Alberto
Published in Nature reviews. Clinical oncology (01.08.2021)
Published in Nature reviews. Clinical oncology (01.08.2021)
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Early‐onset colorectal cancer in young individuals
Mauri, Gianluca, Sartore‐Bianchi, Andrea, Russo, Antonio‐Giampiero, Marsoni, Silvia, Bardelli, Alberto, Siena, Salvatore
Published in Molecular oncology (01.02.2019)
Published in Molecular oncology (01.02.2019)
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Exploring the links between cancer and placenta development
Costanzo, Vincenzo, Bardelli, Alberto, Siena, Salvatore, Abrignani, Sergio
Published in Open biology (01.06.2018)
Published in Open biology (01.06.2018)
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Adaptive mutability of colorectal cancers in response to targeted therapies
Russo, Mariangela, Crisafulli, Giovanni, Sogari, Alberto, Reilly, Nicole M, Arena, Sabrina, Lamba, Simona, Bartolini, Alice, Amodio, Vito, Magrì, Alessandro, Novara, Luca, Sarotto, Ivana, Nagel, Zachary D, Piett, Cortt G, Amatu, Alessio, Sartore-Bianchi, Andrea, Siena, Salvatore, Bertotti, Andrea, Trusolino, Livio, Corigliano, Mattia, Gherardi, Marco, Lagomarsino, Marco Cosentino, Di Nicolantonio, Federica, Bardelli, Alberto
Published in Science (American Association for the Advancement of Science) (20.12.2019)
Published in Science (American Association for the Advancement of Science) (20.12.2019)
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Journal Article
Biomarkers Predicting Clinical Outcome of Epidermal Growth Factor Receptor–Targeted Therapy in Metastatic Colorectal Cancer
Siena, Salvatore, Sartore-Bianchi, Andrea, Di Nicolantonio, Federica, Balfour, Julia, Bardelli, Alberto
Published in JNCI : Journal of the National Cancer Institute (07.10.2009)
Published in JNCI : Journal of the National Cancer Institute (07.10.2009)
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Journal Article
Plasma HER2 ( ERBB2 ) Copy Number Predicts Response to HER2-targeted Therapy in Metastatic Colorectal Cancer
Siravegna, Giulia, Sartore-Bianchi, Andrea, Nagy, Rebecca J, Raghav, Kanwal, Odegaard, Justin I, Lanman, Richard B, Trusolino, Livio, Marsoni, Silvia, Siena, Salvatore, Bardelli, Alberto
Published in Clinical cancer research (15.05.2019)
Published in Clinical cancer research (15.05.2019)
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Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients
Siravegna, Giulia, Mussolin, Benedetta, Buscarino, Michela, Corti, Giorgio, Cassingena, Andrea, Crisafulli, Giovanni, Ponzetti, Agostino, Cremolini, Chiara, Amatu, Alessio, Lauricella, Calogero, Lamba, Simona, Hobor, Sebastijan, Avallone, Antonio, Valtorta, Emanuele, Rospo, Giuseppe, Medico, Enzo, Motta, Valentina, Antoniotti, Carlotta, Tatangelo, Fabiana, Bellosillo, Beatriz, Veronese, Silvio, Budillon, Alfredo, Montagut, Clara, Racca, Patrizia, Marsoni, Silvia, Falcone, Alfredo, Corcoran, Ryan B, Di Nicolantonio, Federica, Loupakis, Fotios, Siena, Salvatore, Sartore-Bianchi, Andrea, Bardelli, Alberto
Published in Nature medicine (01.07.2015)
Published in Nature medicine (01.07.2015)
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Journal Article
Sorafenib in radioactive iodine-refractory, locally advanced or metastatic differentiated thyroid cancer: a randomised, double-blind, phase 3 trial
Brose, Marcia S, Dr, Nutting, Christopher M, Prof, Jarzab, Barbara, Prof, Elisei, Rossella, Prof, Siena, Salvatore, MD, Bastholt, Lars, MD, de la Fouchardiere, Christelle, MD, Pacini, Furio, Prof, Paschke, Ralf, Prof, Shong, Young Kee, Prof, Sherman, Steven I, Prof, Smit, Johannes W A, Prof, Chung, John, MD, Kappeler, Christian, PhD, Peña, Carol, PhD, Molnár, István, MD, Schlumberger, Martin J, Prof
Published in The Lancet (British edition) (26.07.2014)
Published in The Lancet (British edition) (26.07.2014)
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Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer
Misale, Sandra, Yaeger, Rona, Hobor, Sebastijan, Scala, Elisa, Janakiraman, Manickam, Liska, David, Valtorta, Emanuele, Schiavo, Roberta, Buscarino, Michela, Siravegna, Giulia, Bencardino, Katia, Cercek, Andrea, Chen, Chin-Tung, Veronese, Silvio, Zanon, Carlo, Sartore-Bianchi, Andrea, Gambacorta, Marcello, Gallicchio, Margherita, Vakiani, Efsevia, Boscaro, Valentina, Medico, Enzo, Weiser, Martin, Siena, Salvatore, Di Nicolantonio, Federica, Solit, David, Bardelli, Alberto
Published in Nature (London) (28.06.2012)
Published in Nature (London) (28.06.2012)
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Journal Article
Mutant KRAS Codon 12 and 13 Alleles in Patients With Metastatic Colorectal Cancer: Assessment As Prognostic and Predictive Biomarkers of Response to Panitumumab
PEETERS, Marc, DOUILLARD, Jean-Yves, VAN CUTSEM, Eric, SIENA, Salvatore, ZHANG, Kathy, WILLIAMS, Richard, WIEZOREK, Jeffrey
Published in Journal of clinical oncology (20.02.2013)
Published in Journal of clinical oncology (20.02.2013)
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Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): an international, multicentre, randomised, placebo-controlled, phase 3 trial
Grothey, Axel, MD, Cutsem, Eric Van, Prof, Sobrero, Alberto, MD, Siena, Salvatore, MD, Falcone, Alfredo, MD, Ychou, Marc, MD, Humblet, Yves, MD, Bouché, Olivier, MD, Mineur, Laurent, MD, Barone, Carlo, MD, Adenis, Antoine, MD, Tabernero, Josep, MD, Yoshino, Takayuki, MD, Lenz, Heinz-Josef, MD, Goldberg, Richard M, MD, Sargent, Daniel J, PhD, Cihon, Frank, MS, Cupit, Lisa, MD, Wagner, Andrea, MD, Laurent, Dirk, DrMed
Published in The Lancet (British edition) (26.01.2013)
Published in The Lancet (British edition) (26.01.2013)
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Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer
Barault, Ludovic, Amatu, Alessio, Siravegna, Giulia, Ponzetti, Agostino, Moran, Sebastian, Cassingena, Andrea, Mussolin, Benedetta, Falcomatà, Chiara, Binder, Alexandra M, Cristiano, Carmen, Oddo, Daniele, Guarrera, Simonetta, Cancelliere, Carlotta, Bustreo, Sara, Bencardino, Katia, Maden, Sean, Vanzati, Alice, Zavattari, Patrizia, Matullo, Giuseppe, Truini, Mauro, Grady, William M, Racca, Patrizia, Michels, Karin B, Siena, Salvatore, Esteller, Manel, Bardelli, Alberto, Sartore-Bianchi, Andrea, Di Nicolantonio, Federica
Published in Gut (01.11.2018)
Published in Gut (01.11.2018)
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The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets
Medico, Enzo, Russo, Mariangela, Picco, Gabriele, Cancelliere, Carlotta, Valtorta, Emanuele, Corti, Giorgio, Buscarino, Michela, Isella, Claudio, Lamba, Simona, Martinoglio, Barbara, Veronese, Silvio, Siena, Salvatore, Sartore-Bianchi, Andrea, Beccuti, Marco, Mottolese, Marcella, Linnebacher, Michael, Cordero, Francesca, Di Nicolantonio, Federica, Bardelli, Alberto
Published in Nature communications (30.04.2015)
Published in Nature communications (30.04.2015)
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Journal Article
Wild-Type BRAF Is Required for Response to Panitumumab or Cetuximab in Metastatic Colorectal Cancer
Di Nicolantonio, Federica, Martini, Miriam, Molinari, Francesca, Sartore-Bianchi, Andrea, Arena, Sabrina, Saletti, Piercarlo, De Dosso, Sara, Mazzucchelli, Luca, Frattini, Milo, Siena, Salvatore, Bardelli, Alberto
Published in Journal of clinical oncology (10.12.2008)
Published in Journal of clinical oncology (10.12.2008)
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Randomized, Phase III Trial of Panitumumab With Infusional Fluorouracil, Leucovorin, and Oxaliplatin (FOLFOX4) Versus FOLFOX4 Alone As First-Line Treatment in Patients With Previously Untreated Metastatic Colorectal Cancer: The PRIME Study
DOUILLARD, Jean-Yves, SIENA, Salvatore, RIVERA, Fernando, KOCAKOVA, Ilona, RUFF, Paul, BLASINSKA-MORAWIEC, Maria, SMAKAL, Martin, CANON, Jean-Luc, ROTHER, Mark, OLINER, Kelly S, WOLF, Michael, GANSERT, Jennifer, CASSIDY, James, TABERNERO, Josep, BURKES, Ronald, BARUGEL, Mario, HUMBLET, Yves, BODOKY, György, CUNNINGHAM, David, JASSEM, Jacek
Published in Journal of clinical oncology (01.11.2010)
Published in Journal of clinical oncology (01.11.2010)
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Journal Article
CDK4/6 Inhibitors in Breast Cancer Treatment: Potential Interactions with Drug, Gene, and Pathophysiological Conditions
Roncato, Rossana, Angelini, Jacopo, Pani, Arianna, Cecchin, Erika, Sartore-Bianchi, Andrea, Siena, Salvatore, De Mattia, Elena, Scaglione, Francesco, Toffoli, Giuseppe
Published in International journal of molecular sciences (01.09.2020)
Published in International journal of molecular sciences (01.09.2020)
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Journal Article
ALK, ROS1, and NTRK Rearrangements in Metastatic Colorectal Cancer
Pietrantonio, Filippo, Di Nicolantonio, Federica, Schrock, Alexa B, Lee, Jeeyun, Tejpar, Sabine, Sartore-Bianchi, Andrea, Hechtman, Jaclyn F, Christiansen, Jason, Novara, Luca, Tebbutt, Niall, Fucà, Giovanni, Antoniotti, Carlotta, Kim, Seung Tae, Murphy, Danielle, Berenato, Rosa, Morano, Federica, Sun, James, Min, Bosun, Stephens, Philip J, Chen, Marissa, Lazzari, Luca, Miller, Vincent A, Shoemaker, Robert, Amatu, Alessio, Milione, Massimo, Ross, Jeffrey S, Siena, Salvatore, Bardelli, Alberto, Ali, Siraj M, Falcone, Alfredo, de Braud, Filippo, Cremolini, Chiara
Published in JNCI : Journal of the National Cancer Institute (01.12.2017)
Published in JNCI : Journal of the National Cancer Institute (01.12.2017)
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Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies
BENVENUTI, Silvia, SARTORE-BIANCHI, Andrea, DI NICOLANTONIO, Federica, ZANON, Carlo, MORONI, Mauro, VERONESE, Silvio, SIENA, Salvatore, BARDELLI, Alberto
Published in Cancer research (Chicago, Ill.) (15.03.2007)
Published in Cancer research (Chicago, Ill.) (15.03.2007)
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