Genome-wide association analysis identifies genetic correlates of immune infiltrates in solid tumors
Siemers, Nathan O, Holloway, James L, Chang, Han, Chasalow, Scott D, Ross-MacDonald, Petra B, Voliva, Charles F, Szustakowski, Joseph D
Published in PloS one (27.07.2017)
Published in PloS one (27.07.2017)
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Journal Article
Cancer-associated fibroblasts are the main contributors to epithelial-to-mesenchymal signatures in the tumor microenvironment
Szabo, Peter M, Vajdi, Amir, Kumar, Namit, Tolstorukov, Michael Y, Chen, Benjamin J, Edwards, Robin, Ligon, Keith L, Chasalow, Scott D, Chow, Kin-Hoe, Shetty, Aniket, Bolisetty, Mohan, Holloway, James L, Golhar, Ryan, Kidd, Brian A, Hull, Philip Ansumana, Houser, Jeff, Vlach, Logan, Siemers, Nathan O, Saha, Saurabh
Published in Scientific reports (21.02.2023)
Published in Scientific reports (21.02.2023)
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Journal Article
Nearest Neighbor Networks: clustering expression data based on gene neighborhoods
Huttenhower, Curtis, Flamholz, Avi I, Landis, Jessica N, Sahi, Sauhard, Myers, Chad L, Olszewski, Kellen L, Hibbs, Matthew A, Siemers, Nathan O, Troyanskaya, Olga G, Coller, Hilary A
Published in BMC bioinformatics (12.07.2007)
Published in BMC bioinformatics (12.07.2007)
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Journal Article
Analyses of PD-L1 and Inflammatory Gene Expression Association with Efficacy of Nivolumab ± Ipilimumab in Gastric Cancer/Gastroesophageal Junction Cancer
Lei, Ming, Siemers, Nathan O, Pandya, Dimple, Chang, Han, Sanchez, Teresa, Harbison, Christopher, Szabo, Peter M, Janjigian, Yelena, Ott, Patrick A, Sharma, Padmanee, Bendell, Johanna, Evans, Thomas R Jeffry, de Braud, Filippo, Chau, Ian, Boyd, Zachary
Published in Clinical cancer research (15.07.2021)
Published in Clinical cancer research (15.07.2021)
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Journal Article
An immune-active tumor microenvironment favors clinical response to ipilimumab
Ji, Rui-Ru, Chasalow, Scott D., Wang, Lisu, Hamid, Omid, Schmidt, Henrik, Cogswell, John, Alaparthy, Suresh, Berman, David, Jure-Kunkel, Maria, Siemers, Nathan O., Jackson, Jeffrey R., Shahabi, Vafa
Published in Cancer Immunology, Immunotherapy (01.07.2012)
Published in Cancer Immunology, Immunotherapy (01.07.2012)
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Journal Article
Fc-optimized Anti-CCR8 Antibody Depletes Regulatory T Cells in Human Tumor Models
Campbell, Joseph R, McDonald, Bryan R, Mesko, Paul B, Siemers, Nathan O, Singh, Priti B, Selby, Mark, Sproul, Tim W, Korman, Alan J, Vlach, Logan M, Houser, Jeff, Sambanthamoorthy, Sharmila, Lu, Kai, Hatcher, Sandra V, Lohre, Jack, Jain, Renu, Lan, Ruth Y
Published in Cancer research (Chicago, Ill.) (01.06.2021)
Published in Cancer research (Chicago, Ill.) (01.06.2021)
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Journal Article
Transcriptional profiling of the dose response: a more powerful approach for characterizing drug activities
Ji, Rui-Ru, de Silva, Heshani, Jin, Yisheng, Bruccoleri, Robert E, Cao, Jian, He, Aiqing, Huang, Wenjun, Kayne, Paul S, Neuhaus, Isaac M, Ott, Karl-Heinz, Penhallow, Becky, Cockett, Mark I, Neubauer, Michael G, Siemers, Nathan O, Ross-Macdonald, Petra
Published in PLoS computational biology (01.09.2009)
Published in PLoS computational biology (01.09.2009)
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Journal Article
Exome sequencing reveals comprehensive genomic alterations across eight cancer cell lines
Chang, Han, Jackson, Donald G, Kayne, Paul S, Ross-Macdonald, Petra B, Ryseck, Rolf-Peter, Siemers, Nathan O
Published in PloS one (20.06.2011)
Published in PloS one (20.06.2011)
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Journal Article
Gene set enrichment analysis
Tilford, Charles A, Siemers, Nathan O
Published in Methods in molecular biology (Clifton, N.J.) (2009)
Published in Methods in molecular biology (Clifton, N.J.) (2009)
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Journal Article
HBEGF, SRA1, and IK: Three cosegregating genes as determinants of cardiomyopathy
Friedrichs, Frauke, Zugck, Christian, Rauch, Gerd-Jörg, Ivandic, Boris, Weichenhan, Dieter, Müller-Bardorff, Margit, Meder, Benjamin, El Mokhtari, Nour Eddine, Regitz-Zagrosek, Vera, Hetzer, Roland, Schäfer, Arne, Schreiber, Stefan, Chen, Jian, Neuhaus, Isaac, Ji, Ruiru, Siemers, Nathan O, Frey, Norbert, Rottbauer, Wolfgang, Katus, Hugo A, Stoll, Monika
Published in Genome Research (01.03.2009)
Published in Genome Research (01.03.2009)
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Journal Article
SDRS—an algorithm for analyzing large-scale dose–response data
Ji, Rui-Ru, Siemers, Nathan O, Lei, Ming, Schweizer, Liang, Bruccoleri, Robert E
Published in Bioinformatics (15.10.2011)
Published in Bioinformatics (15.10.2011)
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Journal Article
Development and Activities of a New Melphalan Prodrug Designed for Tumor-Selective Activation
Kerr, David E, Li, Zhengong, Siemers, Nathan O, Senter, Peter D, Vrudhula, Vivekananda M
Published in Bioconjugate chemistry (01.03.1998)
Published in Bioconjugate chemistry (01.03.1998)
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Journal Article
종양을 치료하는 방법
SANCHEZ TERESA K, PANDYA DIMPLE, HARBISON CHRISTOPHER T, BOYD ZACHARY S, CHANG HAN, LEI MING, SIEMERS NATHAN O, WALSH ALICE M, SZABO PETER M
Year of Publication 03.12.2021
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Year of Publication 03.12.2021
Patent
암을 치료하기 위한 항-CCR8 항체
SELBY MARK J, LEE JOHN K, ADELAKUN OLUFEMI A, CAMPBELL JOSEPH RICHARD, MCDONALD BRYAN, LEE PETER SUNG KEUN, MESKO PAUL BLAINE, LU KAI, GREENAWALT DANIELLE M, LIANG LINDA, JAIN RENU, LAN RUTH YIN ZONG, RAJPAL ARVIND, TERRACINA GABY A, FINDEISEN FELIX, SAMBANTHAMOORTHY SHARMILA, BARMAN ISHITA, SIEMERS NATHAN O, DIONG SJ JIAN ZHE, STROP PAVEL, WANG XI TAO, JHATAKIA AMY D
Year of Publication 29.11.2022
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Year of Publication 29.11.2022
Patent
Cephalosporin prodrugs of paclitaxel for immunologically specific activation by L-49-sFv-β-Lactamase fusion protein
Vrudhula, Vivekananda M., Kerr, David E., Siemers, Nathan O., Dubowchik, Gene M., Senter, Peter D.
Published in Bioorganic & medicinal chemistry letters (10.02.2003)
Published in Bioorganic & medicinal chemistry letters (10.02.2003)
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Journal Article
종양을 치료하는 방법
SACI SAMY ABDEL, HARBISON CHRISTOPHER T, JACKSON DONALD G, LEI MING, WALSH ALICE M, SZABO PETER M, QIAN XIAOZHONG, YOUNG TINA C, RIZZO JASMINE, SANCHEZ TERESA K, SRINIVASAN SUJAYA, PANDYA DIMPLE, BOYD ZACHARY S, CHANG HAN, SIEMERS NATHAN O, WIND ROTOLO MEGAN M
Year of Publication 03.12.2021
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Year of Publication 03.12.2021
Patent
Structural and functional characterization of CFE88: Evidence that a conserved and essential bacterial protein is a methyltransferase
Constantine, Keith L., Krystek, Stanley R., Healy, Matthew D., Doyle, Michael L., Siemers, Nathan O., Thanassi, Jane, Yan, Ning, Xie, Dianlin, Goldfarb, Valentina, Yanchunas, Joseph, Tao, Li, Dougherty, Brian A., Farmer, Bennett T.
Published in Protein science (01.06.2005)
Published in Protein science (01.06.2005)
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Journal Article
Comparison of Recombinant and Synthetically Formed Monoclonal Antibody-β-Lactamase Conjugates for Anticancer Prodrug Activation
Kerr, David E, Vrudhula, Vivekananda M, Svensson, Håkan P, Siemers, Nathan O, Senter, Peter D
Published in Bioconjugate chemistry (01.11.1999)
Published in Bioconjugate chemistry (01.11.1999)
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Journal Article