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Comparison of electrocardiographic analysis for risk of QT interval prolongation using safety pharmacology and toxicological studies
Guth, B.D., Bass, A.S., Briscoe, R., Chivers, S., Markert, M., Siegl, P.K.S., Valentin, J.-P.
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Torcetrapib-induced blood pressure elevation is independent of CETP inhibition and is accompanied by increased circulating levels of aldosterone. Commenary
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A potent, orally active, balanced affinity angiotensin II AT1 antagonist and AT2 binding inhibitor
de Laszlo, Stephen E, Quagliato, Carol S, Greenlee, William J, Patchett, Arthur A, Chang, Raymond S. L, Lotti, Victor J, Chen, Tsing Bau, Scheck, Stacey A, Faust, Kristi A
Published in Journal of medicinal chemistry (01.10.1993)
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Potent, orally active imidazo[4,5-b]pyridine-based angiotensin II receptor antagonists
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Published in The Journal of pharmacology and experimental therapeutics (01.07.1992)
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Published in Proceedings of the National Academy of Sciences - PNAS (15.05.1984)
Published in Proceedings of the National Academy of Sciences - PNAS (15.05.1984)
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Published in The Journal of pharmacology and experimental therapeutics (01.07.1992)
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Antithrombotic efficacy of recombinant tick anticoagulant peptide : a potent inhibitor of coagulation factor Xa in a primate model of arterial thrombosis
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Published in Circulation (New York, N.Y.) (01.10.1991)
Published in Circulation (New York, N.Y.) (01.10.1991)
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A highly potent, orally active imidazo-[4,5-b]pyridine biphenylacylsulfonamide (MK-996;L-159,282) : a new AT1-selective angiotensin II receptor antagonist
CHAKRAVARTY, P. K, NAYLOR, E. M, SCHORN, T. W, SCHAFFER, L. W, BROTEN, T. P, SIEGL, P. K. S, PATCHETT, A. A, GREENLEE, W. J, CHEN, A, CHANG, R. S. L, TSING-BAU CHEN, FAUST, K. A, LOTTI, V. J, KIVLIGHN, S. D, GABLE, R. A, ZINGARO, G. J
Published in Journal of medicinal chemistry (25.11.1994)
Published in Journal of medicinal chemistry (25.11.1994)
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Triazolinone Biphenylsulfonamides as Angiotensin II Receptor Antagonists with High Affinity for Both the AT1 and AT2 Subtypes
Chang, Linda L, Ashton, Wallace T, Flanagan, Kelly L, Chen, Tsing-Bau, O'Malley, Stacey S, Zingaro, Gloria J, Siegl, Peter K. S, Kivlighn, Salah D, Lotti, Victor J
Published in Journal of medicinal chemistry (01.12.1994)
Published in Journal of medicinal chemistry (01.12.1994)
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