Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development
REDFERN, W. S, CARLSSON, L, CAMM, A. J, HAMMOND, T. G, DAVIS, A. S, LYNCH, W. G, MACKENZIE, I, PALETHORPE, S, SIEGL, P. K. S, STRANG, I, SULLIVAN, A. T, WALLIS, R
Published in Cardiovascular research (01.04.2003)
Published in Cardiovascular research (01.04.2003)
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Journal Article
Torcetrapib‐induced blood pressure elevation is independent of CETP inhibition and is accompanied by increased circulating levels of aldosterone
Forrest, M J, Bloomfield, D, Briscoe, R J, Brown, P N, Cumiskey, A‐M, Ehrhart, J, Hershey, J C, Keller, W J, Ma, X, McPherson, H E, Messina, E, Peterson, L B, Sharif‐Rodriguez, W, Siegl, P K S, Sinclair, P J, Sparrow, C P, Stevenson, A S, Sun, S‐Y, Tsai, C, Vargas, H, Walker, M, West, S H, White, V, Woltmann, R F
Published in British journal of pharmacology (01.08.2008)
Published in British journal of pharmacology (01.08.2008)
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Journal Article
Non-accretive Schrödinger operators and exponential decay of their eigenfunctions
Krejčiřík, D., Raymond, N., Royer, J., Siegl, P.
Published in Israel journal of mathematics (01.09.2017)
Published in Israel journal of mathematics (01.09.2017)
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Journal Article
New SUSYQM coherent states for Pöschl-Teller potentials: a detailed mathematical analysis
Bergeron, H, Siegl, P, Youssef, A
Published in Journal of physics. A, Mathematical and theoretical (22.06.2012)
Published in Journal of physics. A, Mathematical and theoretical (22.06.2012)
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Journal Article
The Pauli equation with complex boundary conditions
Kochan, D, Krej i ík, D, Novák, R, Siegl, P
Published in Journal of physics. A, Mathematical and theoretical (09.11.2012)
Published in Journal of physics. A, Mathematical and theoretical (09.11.2012)
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Journal Article
Comparison of electrocardiographic analysis for risk of QT interval prolongation using safety pharmacology and toxicological studies
Guth, B.D., Bass, A.S., Briscoe, R., Chivers, S., Markert, M., Siegl, P.K.S., Valentin, J.-P.
Published in Journal of pharmacological and toxicological methods (01.09.2009)
Published in Journal of pharmacological and toxicological methods (01.09.2009)
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Journal Article
Complement dependent cytotoxicity (CDC) activity of a humanized anti Lewis-Y antibody: FACS-based assay versus the ‘classical’ radioactive method—Qualification, comparison and application of the FACS-based approach
Nechansky, A., Szolar, O.H.J., Siegl, P., Zinoecker, I., Halanek, N., Wiederkum, S., Kircheis, R.
Published in Journal of pharmaceutical and biomedical analysis (01.05.2009)
Published in Journal of pharmaceutical and biomedical analysis (01.05.2009)
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Journal Article
A novel standard food model to analyze the individual parameters of human mastication
Slavicek, G., Soykher, M., Gruber, H., Siegl, P., Oxtoby, M.
Published in International journal of stomatology & occlusion medicine (01.12.2009)
Published in International journal of stomatology & occlusion medicine (01.12.2009)
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Journal Article
A standardized procedure to record human speech trajectories
Gruber, H., Slavicek, G., Siegl, P.
Published in International journal of stomatology & occlusion medicine (01.06.2010)
Published in International journal of stomatology & occlusion medicine (01.06.2010)
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Journal Article
Periodontitis and atherosclerotic cardiovascular disease
Slavicek, G., Gruber, H., Siegl, P., Slavicek, B.
Published in International journal of stomatology & occlusion medicine (01.09.2009)
Published in International journal of stomatology & occlusion medicine (01.09.2009)
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Journal Article
The use of intraoral splints: a case report
Slavicek, G., Siegl, P., Gruber, H.
Published in International journal of stomatology & occlusion medicine (01.06.2009)
Published in International journal of stomatology & occlusion medicine (01.06.2009)
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Journal Article
In vitro pharmacology of L-158,809, a new highly potent and selective angiotensin II receptor antagonist
CHANG, R. S. L, SIEGL, P. K. S, CLINESCHMIDT, B. V, MANTLO, N. B, CHAKRAVARTY, P. K, GREENLEE, W. J, PATCHETT, A. A, LOTTI, V. J
Published in The Journal of pharmacology and experimental therapeutics (01.07.1992)
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Published in The Journal of pharmacology and experimental therapeutics (01.07.1992)
Journal Article
In vivo pharmacology of L-158,809, a new highly potent and selective nonpeptide angiotensin II receptor antagonist
SIEGL, P. K. S, CHANG, R. S. L, MANTLO, N. B, CHAKRAVARTY, P. K, ONDEYKA, D. L, GREENLEE, W. J, PATCHETT, A. A, SWEET, C. S, LOTTI, V. J
Published in The Journal of pharmacology and experimental therapeutics (01.07.1992)
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Published in The Journal of pharmacology and experimental therapeutics (01.07.1992)
Journal Article
Antithrombotic efficacy of recombinant tick anticoagulant peptide : a potent inhibitor of coagulation factor Xa in a primate model of arterial thrombosis
SCHAFFER, L. W, DAVIDSON, J. T, VLASUK, G. P, SIEGL, P. K. S
Published in Circulation (New York, N.Y.) (01.10.1991)
Published in Circulation (New York, N.Y.) (01.10.1991)
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Conference Proceeding
Journal Article
Pathophysiological Roles of Endothelin-1 in Dahl Salt-Sensitive Hypertension
Ikeda, Takanori, Ohta, Hisashi, Okada, Megumu, Kawai, Nobuko, Nakao, Rumi, Siegl, Peter K.S, Kobayashi, Tsutomu, Maeda, Seiji, Miyauchi, Takashi, Nishikibe, Masaru
Published in Hypertension (Dallas, Tex. 1979) (01.09.1999)
Published in Hypertension (Dallas, Tex. 1979) (01.09.1999)
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Journal Article
Lack of beneficial effects of growth hormone treatment in conscious dogs during development of heart failure
Shen, You-Tang, Woltmann, R. F, Appleby, S, Prahalada, S, Krause, S. M, Kivilghn, S. D, Johnson, R. G, Siegl, P. K, Lynch, J. J
Published in American journal of physiology. Heart and circulatory physiology (01.02.1998)
Published in American journal of physiology. Heart and circulatory physiology (01.02.1998)
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Journal Article