Inflammation (or synovitis)-driven osteoarthritis: an opportunity for personalizing prognosis and treatment?
Siebuhr, AS, Bay-Jensen, AC, Jordan, JM, Kjelgaard-Petersen, CF, Christiansen, C, Abramson, SB, Attur, M, Berenbaum, F, Kraus, V, Karsdal, MA
Published in Scandinavian journal of rheumatology (03.03.2016)
Published in Scandinavian journal of rheumatology (03.03.2016)
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Journal Article
Disease-modifying treatments for osteoarthritis (DMOADs) of the knee and hip: lessons learned from failures and opportunities for the future
Karsdal, M.A, Michaelis, M, Ladel, C, Siebuhr, A.S, Bihlet, A.R, Andersen, J.R, Guehring, H, Christiansen, C, Bay-Jensen, A.C, Kraus, V.B
Published in Osteoarthritis and cartilage (01.12.2016)
Published in Osteoarthritis and cartilage (01.12.2016)
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Journal Article
POS0431 FIBROBLASTS ARE NOT JUST FIBROBLASTS - CLEAR DIFFERENCES IN ECM PRODUCTION BETWEEN DERMAL AND LUNG FIBROBLASTS IN RESPONSE TO GROWTH FACTORS
Madsen, S. F., Siebuhr, A. S., Jessen, H., Sand, J. M. B., Karsdal, M., Bay-Jensen, A. C.
Published in Annals of the rheumatic diseases (01.06.2021)
Published in Annals of the rheumatic diseases (01.06.2021)
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Journal Article
Sprifermin (rhFGF18) versus vehicle induces a biphasic process of extracellular matrix remodeling in human knee OA articular cartilage ex vivo
Reker, D., Siebuhr, A. S., Thudium, C. S., Gantzel, T., Ladel, C., Michaelis, M., Aspberg, A., Berchtold, M. W., Karsdal, M. A., Gigout, A., Bay-Jensen, A. C.
Published in Scientific reports (07.04.2020)
Published in Scientific reports (07.04.2020)
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Journal Article
Identification and characterisation of osteoarthritis patients with inflammation derived tissue turnover
Siebuhr, A.S, Petersen, K.K, Arendt-Nielsen, L, Egsgaard, L.L, Eskehave, T, Christiansen, C, Simonsen, O, Hoeck, H.C, Karsdal, M.A, Bay-Jensen, A.C
Published in Osteoarthritis and cartilage (01.01.2014)
Published in Osteoarthritis and cartilage (01.01.2014)
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Journal Article
Association between biochemical cartilage markers and clinical symptoms in patients with hip osteoarthritis: cohort study with 2-year follow-up
Dorleijn, D.M.J, Luijsterburg, P.A.J, Bay-Jensen, A.C, Siebuhr, A.S, Karsdal, M.A, Rozendaal, R.M, Bos, P.K, Bierma-Zeinstra, S.M.A
Published in Osteoarthritis and cartilage (01.01.2015)
Published in Osteoarthritis and cartilage (01.01.2015)
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Journal Article
FRI0084 Structural progressors in rheumatoid arthritis identified by serology – identification of the patients in most need of intensive treatment
Karsdal, M. A., Siebuhr, A. S., Leeming, D. J., Byrjalsen, I., Christiansen, C., Platt, A., Bay-Jensen, A.-C.
Published in Annals of the rheumatic diseases (01.06.2013)
Published in Annals of the rheumatic diseases (01.06.2013)
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Journal Article
SAT0317 Identification of Osteoarthritis Patients with Chronic Tissue Inflammation Whom may Benefit from Anti-Inflammatory Treatment
Siebuhr, A. S., Petersen, K. K., Arendt-Nielsen, L., Egsgaard, L. L., Eskehave, T., Christiansen, C., Simonsen, O., Hoeck, H. C., Karsdal, M. A., Bay-Jensen, A. C.
Published in Annals of the rheumatic diseases (01.06.2013)
Published in Annals of the rheumatic diseases (01.06.2013)
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Journal Article
Circulating levels of MMP-mediated connective tissue destruction is predictive of structural progression in patients with inflammatory arthritis
Siebuhr, A.-S, Bay-Jensen, A.-C, Leeming, D.J, Platt, A, Byrjalsen, I, Christiansen, C, van der Heijde, D, Karsdal;, M
Published in Osteoarthritis and cartilage (01.04.2013)
Published in Osteoarthritis and cartilage (01.04.2013)
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Journal Article
Investigating the Robustness and Diagnostic Potential of Extracellular Matrix Remodelling Biomarkers in Alkaptonuria
Genovese, F., Siebuhr, A. S., Musa, K., Gallagher, J. A., Milan, A. M., Karsdal, M. A., Rovensky, J., Bay-Jensen, A. C., Ranganath, L. R.
Published in JIMD Reports, Volume 24 (01.01.2015)
Published in JIMD Reports, Volume 24 (01.01.2015)
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Book Chapter
Journal Article
AB0167 TOFACITINIB AND NINTEDANIB MODULATE COLLAGEN FORMATION IN DERMAL FIBROBLASTS
Siebuhr, A. S., Karsdal, M., Juhl, P., Bay-Jensen, A. C.
Published in Annals of the rheumatic diseases (01.06.2020)
Published in Annals of the rheumatic diseases (01.06.2020)
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Journal Article
SAT0298 IS INTERLEUKIN 6 A FACTOR OF FIBROGENESIS IN DERMAL FIBROBLASTS?
Siebuhr, A. S., Juhl, P., Karsdal, M., Bay-Jensen, A. C.
Published in Annals of the rheumatic diseases (01.06.2020)
Published in Annals of the rheumatic diseases (01.06.2020)
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Journal Article
OP0252 CIRCULATING COLLAGEN TURNOVER MARKERS ARE SPECIFICALLY CHANGED IN VERY EARLY SYSTEMIC SCLEROSIS
Dobrota, R., Jordan, S., Juhl, P., Maurer, B., Becker, M. O., Mihai, C., Bay-Jensen, A. C., Karsdal, M., Siebuhr, A. S., Distler, O.
Published in Annals of the rheumatic diseases (01.06.2020)
Published in Annals of the rheumatic diseases (01.06.2020)
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Journal Article
Type IV collagen metabolism is associated with disease activity, radiographic progression and response to tocilizumab in rheumatoid arthritis
Gudmann, Natasja Stæhr, Junker, Peter, Juhl, Pernille, Thudium, Christian Schneider, Siebuhr, Anne Sofie, Byrjalsen, Inger, Karsdal, Morten Asser, Bay-Jensen, Anne Christine
Published in Clinical and experimental rheumatology (01.09.2018)
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Published in Clinical and experimental rheumatology (01.09.2018)
Journal Article
Pharmacokinetic and pharmacodynamic modelling of the novel anti-ADAMTS-5 nanobody M6495 using the neo-epitope ARGS as a biomarker
Pereira, J., Ottevaere, I., Serruys, B., Dejonckheere, E., Bay-Jensen, A.-C., Siebuhr, A.-S., El Bawab, S., Ladel, C., Lindemann, S.
Published in Osteoarthritis and cartilage (01.04.2018)
Published in Osteoarthritis and cartilage (01.04.2018)
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Journal Article
Suppression of active, but not total MMP-3, is associated with treatment response in a phase III clinical study of rheumatoid arthritis
Siebuhr, Anne Sofie, Kjelgaard-Petersen, Cecilie F, Sun, Shu, Byrjalsen, Inger, Christiansen, Claus, Karsdal, Morten Asser, Bay-Jensen, Anne-Christine
Published in Clinical and experimental rheumatology (01.01.2018)
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Published in Clinical and experimental rheumatology (01.01.2018)
Journal Article
Type I and III collagen turnover is increased in axial spondyloarthritis and psoriatic arthritis. Associations with disease activity and diagnostic capacity
Gudmann, Natasja Stæhr, Siebuhr, Anne Sofie, Christensen, Anne Friesgaard, Ejstrup, Leif, Sørensen, Grith Lykke, Loft, Anne Gitte, Karsdal, Morten Asser, Bay-Jensen, Anne-Christine, Munk, Heidi Lausten, Junker, Peter
Published in Clinical and experimental rheumatology (01.07.2017)
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Published in Clinical and experimental rheumatology (01.07.2017)
Journal Article
Association Between Experimental Pain Biomarkers and Serologic Markers in Patients With Different Degrees of Painful Knee Osteoarthritis
Arendt‐Nielsen, Lars, Eskehave, Thomas N., Egsgaard, Line L., Petersen, Kristian K., Graven‐Nielsen, Thomas, Hoeck, Hans C., Simonsen, Ole, Siebuhr, Anne S., Karsdal, Morten, Bay‐Jensen, Anne C.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2014)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2014)
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Journal Article