Current use and future potential of (physiologically based) pharmacokinetic modelling of radiopharmaceuticals: a review
Siebinga, Hinke, de Wit-van der Veen, Berlinda J, Stokkel, Marcel D M, Huitema, Alwin D R, Hendrikx, Jeroen J M A
Published in Theranostics (01.01.2022)
Published in Theranostics (01.01.2022)
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Journal Article
Predicting the effect of different folate doses on [68Ga]Ga-PSMA-11 organ and tumor uptake using physiologically based pharmacokinetic modeling
Siebinga, Hinke, Hendrikx, Jeroen J. M. A., Huitema, Alwin D. R., de Wit-van der Veen, Berlinda J.
Published in EJNMMI research (15.06.2023)
Published in EJNMMI research (15.06.2023)
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Journal Article
Population pharmacokinetic dosimetry model using imaging data to assess variability in pharmacokinetics of 177Lu‐PSMA‐617 in prostate cancer patients
Siebinga, Hinke, Privé, Bastiaan M., Peters, Steffie M. B., Nagarajah, James, Dorlo, Thomas P. C., Huitema, Alwin D. R., Wit‐van der Veen, Berlinda J., Hendrikx, Jeroen J. M. A.
Published in CPT: pharmacometrics and systems pharmacology (01.08.2023)
Published in CPT: pharmacometrics and systems pharmacology (01.08.2023)
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Journal Article
Somatostatin receptor saturation after administration of high peptide amounts of [177Lu]Lu-HA-DOTATATE: when enough is enough
Siebinga, Hinke, Veerman, Chayenne H. A. M., de Wit-van der Veen, Linda, Stokkel, Marcel P. M., Hendrikx, Jeroen J. M. A., Aalbersberg, Else A.
Published in EJNMMI research (14.12.2022)
Published in EJNMMI research (14.12.2022)
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Journal Article
A physiologically based pharmacokinetic model for [68Ga]Ga-(HA-)DOTATATE to predict whole-body distribution and tumor sink effects in GEP-NET patients
Siebinga, Hinke, de Wit-van der Veen, Berlinda J., Beijnen, Jos H., Dorlo, Thomas P. C., Huitema, Alwin D. R., Hendrikx, Jeroen J. M. A.
Published in EJNMMI research (03.02.2023)
Published in EJNMMI research (03.02.2023)
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Journal Article
Predicting [177Lu]Lu-HA-DOTATATE kidney and tumor accumulation based on [68Ga]Ga-HA-DOTATATE diagnostic imaging using semi-physiological population pharmacokinetic modeling
Siebinga, Hinke, de Wit-van der Veen, Berlinda J., Beijnen, Jos H., Stokkel, Marcel P. M., Dorlo, Thomas P. C., Huitema, Alwin D. R., Hendrikx, Jeroen J. M. A.
Published in EJNMMI physics (24.08.2023)
Published in EJNMMI physics (24.08.2023)
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Journal Article
The Impact of Peptide Amount on Tumor Uptake to Assess PSMA Receptor Saturation on 68Ga-PSMA-11 PET/CT in Patients with Primary Prostate Cancer
Siebinga, Hinke, Heuvel, Judith Olde, Rijkhorst, Erik-Jan, Hendrikx, Jeroen J M A, de Wit-van der Veen, Berlinda J
Published in The Journal of nuclear medicine (1978) (01.01.2023)
Published in The Journal of nuclear medicine (1978) (01.01.2023)
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Journal Article
The Impact of Peptide Amount on Tumor Uptake to Assess PSMA Receptor Saturation on 68 Ga-PSMA-11 PET/CT in Patients with Primary Prostate Cancer
Siebinga, Hinke, Heuvel, Judith Olde, Rijkhorst, Erik-Jan, Hendrikx, Jeroen J M A, de Wit-van der Veen, Berlinda J
Published in Journal of Nuclear Medicine (01.01.2023)
Published in Journal of Nuclear Medicine (01.01.2023)
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Journal Article
A Population Pharmacokinetic Study to Evaluate Doxorubicin Exposure Across All Age Groups
Mohmaed Ali, Ma Ida, Nijstad, A Laura, Boosman, René J, Crombag, Marie-Rose B S, Barnett, Shelby, Veal, Gareth J, Lalmohamed, Arief, van Erp, Nielka P, Steeghs, Neeltje, Zwaan, C Michel, Beijnen, Jos H, Siebinga, Hinke, Huitema, Alwin D R
Published in Clinical pharmacokinetics (16.11.2024)
Published in Clinical pharmacokinetics (16.11.2024)
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Journal Article
The effect of long-acting somatostatin analogues on the uptake of [177Lu]Lu-HA-DOTATATE
Veerman, Chayenne H. A. M., Siebinga, Hinke, de Vries-Huizing, Daphne M. V., Tesselaar, Margot E. T., Hendrikx, Jeroen J. M. A., Stokkel, Marcel P. M., Aalbersberg, Else A.
Published in European journal of nuclear medicine and molecular imaging (01.04.2023)
Published in European journal of nuclear medicine and molecular imaging (01.04.2023)
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Journal Article
Quantification of biochemical PSA dynamics after radioligand therapy with [177Lu]Lu-PSMA-I T using a population pharmacokinetic/pharmacodynamic model
Hinke Siebinga, Berlinda J. de Wit-van der Veen, Daphne M. V. de Vries-Huizing, Wouter V. Vogel, Jeroen J. M. A. Hendrikx, Alwin D. R. Huitema
Published in EJNMMI physics (01.04.2024)
Published in EJNMMI physics (01.04.2024)
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Journal Article
Population pharmacokinetic dosimetry model using imaging data to assess variability in pharmacokinetics of 177 Lu-PSMA-617 in prostate cancer patients
Siebinga, Hinke, Privé, Bastiaan M, Peters, Steffie M B, Nagarajah, James, Dorlo, Thomas P C, Huitema, Alwin D R, de Wit-van der Veen, Berlinda J, Hendrikx, Jeroen J M A
Published in CPT: pharmacometrics and systems pharmacology (01.08.2023)
Published in CPT: pharmacometrics and systems pharmacology (01.08.2023)
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Journal Article
Quantification of biochemical PSA dynamics after radioligand therapy with [177Lu]Lu-PSMA-I&T using a population pharmacokinetic/pharmacodynamic model
Siebinga, Hinke, de Wit-van der Veen, Berlinda J., de Vries-Huizing, Daphne M. V., Vogel, Wouter V., Hendrikx, Jeroen J. M. A., Huitema, Alwin D. R.
Published in EJNMMI physics (24.04.2024)
Published in EJNMMI physics (24.04.2024)
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Journal Article