Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl
Dou, Hao, Buetow, Lori, Hock, Andreas, Sibbet, Gary J, Vousden, Karen H, Huang, Danny T
Published in Nature structural & molecular biology (01.02.2012)
Published in Nature structural & molecular biology (01.02.2012)
Get full text
Journal Article
Activation of a Primed RING E3-E2–Ubiquitin Complex by Non-Covalent Ubiquitin
Buetow, Lori, Gabrielsen, Mads, Anthony, Nahoum G., Dou, Hao, Patel, Amrita, Aitkenhead, Hazel, Sibbet, Gary J., Smith, Brian O., Huang, Danny T.
Published in Molecular cell (16.04.2015)
Published in Molecular cell (16.04.2015)
Get full text
Journal Article
Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain
Magnussen, Helge M., Ahmed, Syed F., Sibbet, Gary. J., Hristova, Ventzislava A., Nomura, Koji, Hock, Andreas K., Archibald, Lewis J., Jamieson, Andrew G., Fushman, David, Vousden, Karen H., Weissman, Allan M., Huang, Danny T.
Published in Nature communications (29.04.2020)
Published in Nature communications (29.04.2020)
Get full text
Journal Article
Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity
Nomura, Koji, Klejnot, Marta, Kowalczyk, Dominika, Hock, Andreas K, Sibbet, Gary J, Vousden, Karen H, Huang, Danny T
Published in Nature structural & molecular biology (01.07.2017)
Published in Nature structural & molecular biology (01.07.2017)
Get full text
Journal Article
Essentiality of a non-RING element in priming donor ubiquitin for catalysis by a monomeric E3
Dou, Hao, Buetow, Lori, Sibbet, Gary J, Cameron, Kenneth, Huang, Danny T
Published in Nature structural & molecular biology (01.08.2013)
Published in Nature structural & molecular biology (01.08.2013)
Get full text
Journal Article
A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants
Gabrielsen, Mads, Buetow, Lori, Nakasone, Mark A., Ahmed, Syed Feroj, Sibbet, Gary J., Smith, Brian O., Zhang, Wei, Sidhu, Sachdev S., Huang, Danny T.
Published in Molecular cell (19.10.2017)
Published in Molecular cell (19.10.2017)
Get full text
Journal Article
Structural insights into non-covalent ubiquitin activation of the cIAP1-UbcH5B∼ubiquitin complex
Patel, Amrita, Sibbet, Gary J., Huang, Danny T.
Published in The Journal of biological chemistry (25.01.2019)
Published in The Journal of biological chemistry (25.01.2019)
Get full text
Journal Article
E3 ligase-inactivation rewires CBL interactome to elicit oncogenesis by hijacking RTK–CBL–CIN85 axis
Ahmed, Syed Feroj, Buetow, Lori, Gabrielsen, Mads, Lilla, Sergio, Sibbet, Gary J., Sumpton, David, Zanivan, Sara, Hedley, Ann, Clark, William, Huang, Danny T.
Published in Oncogene (25.03.2021)
Published in Oncogene (25.03.2021)
Get full text
Journal Article
Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases
Chatrin, Chatrin, Gabrielsen, Mads, Buetow, Lori, Nakasone, Mark A, Ahmed, Syed F, Sumpton, David, Sibbet, Gary J, Smith, Brian O, Huang, Danny T
Published in Science advances (01.09.2020)
Published in Science advances (01.09.2020)
Get full text
Journal Article
Casitas B-lineage lymphoma linker helix mutations found in myeloproliferative neoplasms affect conformation
Buetow, Lori, Tria, Giancarlo, Ahmed, Syed Feroj, Hock, Andreas, Dou, Hao, Sibbet, Gary J, Svergun, Dmitri I, Huang, Danny T
Published in BMC biology (08.09.2016)
Published in BMC biology (08.09.2016)
Get full text
Journal Article
Down-regulation of MHC class I by bovine papillomavirus E5 oncoproteins
HOSSEIN ASHRAFI, G, TSIRIMONAKI, Emmanouella, MARCHETTI, Barbara, O'BRIEN, Philippa M, SIBBET, Gary J, ANDREW, Linda, CAMPO, M. Saveria
Published in Oncogene (10.01.2002)
Published in Oncogene (10.01.2002)
Get full text
Journal Article