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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

by Ripke, Stephan, Trzaskowski, Maciej, Byrne, Enda M., Adams, Mark J., Andlauer, Till M. F., Bacanu, Silviu-Alin, Beekman, Aartjan F. T., Bigdeli, Tim B., Binder, Elisabeth B., Blackwood, Douglas R. H., Bybjerg-Grauholm, Jonas, Castelao, Enrique, Couvy-Duchesne, Baptiste, Craddock, Nick, Deary, Ian J., Finucane, Hilary K., Forstner, Andreas J., Frank, Josef, Gill, Michael, Goes, Fernando S., Grove, Jakob, Hall, Lynsey S., Hannon, Eilis, Hansen, Thomas F., Hickie, Ian B., Hoffmann, Per, Horn, Carsten, Hougaard, David M., Hyde, Craig L., Jorgenson, Eric, Knowles, James A., Kraft, Julia, Krogh, Jesper, Kutalik, Zoltán, Lane, Jacqueline M., Li, Yihan, Li, Yun, Liu, Xiaoxiao, Lu, Leina, MacIntyre, Donald J., MacKinnon, Dean F., Maier, Robert M., Marchini, Jonathan, Mbarek, Hamdi, McGrath, Patrick, Mehta, Divya, Montgomery, Grant W., Nauck, Matthias, Nivard, Michel G., Pedersen, Carsten Bøcker, Posthuma, Danielle, Purcell, Shaun M., Quiroz, Jorge A., Saeed Mirza, Saira, Schoevers, Robert, Schulte, Eva C., Shi, Jianxin, Shyn, Stanley I., Smit, Johannes H., Smith, Daniel J., Stockmeier, Craig A., Teumer, Alexander, Thompson, Wesley, Thomson, Pippa A., Thorgeirsson, Thorgeir E., Tian, Chao, Treutlein, Jens, van Hemert, Albert M., Viktorin, Alexander, Visscher, Peter M., Wang, Yunpeng, Weinsheimer, Shantel Marie, Wellmann, Jürgen, Witt, Stephanie H., Wu, Yang, Xi, Hualin S., Yang, Jian, Zhang, Futao, Baune, Bernhard T., Berger, Klaus, de Geus, E. C. J., Domschke, Katharina, Esko, Tõnu, Hinds, David A., Li, Qingqin S., McIntosh, Andrew M., Metspalu, Andres, Mors, Ole, Müller-Myhsok, Bertram, O’Donovan, Michael C., Paciga, Sara A., Pedersen, Nancy L., Perlis, Roy H., Potash, James B., Schaefer, Catherine, Schulze, Thomas G., Uher, Rudolf, Völzke, Henry, Winslow, Ashley R., Børglum, Anders D.
Published in Nature genetics (01.05.2018)

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A Comparison of Ten Polygenic Score Methods for Psychiatric Disorders Applied Across Multiple Cohorts

by Ni, Guiyan, Wang, Ying, Ge, Tian, Smoller, Jordan W., Ripke, Stephan, Farh, Kai-How, Holmans, Peter A., Agartz, Ingrid, Belliveau, Richard A., Bigdeli, Tim B., Black, Donald W., Buckner, Randy L., Cheng, Wei, Degenhardt, Franziska, Dudbridge, Frank, Eichhammer, Peter, Farrell, Martilias S., Frank, Josef, Freedman, Robert, Friedl, Marion, Giegling, Ina, Giusti-Rodríguez, Paola, Gratten, Jacob, Hartmann, Annette M., Hollegaard, Mads V., Kahn, René S., Karachanak-Yankova, Sena, Kavanagh, David, Keller, Matthew C., Kennedy, James L., Knowles, James A., Kucinskiene, Zita Ausrele, Li, Tao, Loughland, Carmel M., Lubinski, Jan, Maier, Wolfgang, Mallet, Jacques, Michie, Patricia T., Myin-Germeys, Inez, Nertney, Deborah A., Nicodemus, Kristin K., Nikitina-Zake, Liene, O’Callaghan, Eadbhard, O’Dushlaine, Colm, Pejovic-Milovancevic, Milica, Pocklington, Andrew J., Powell, John, Pulver, Ann E., Ruderfer, Douglas M., Salomaa, Veikko, Shi, Jianxin, Sim, Kang, Slominsky, Petr, Spencer, Chris C.A., Stahl, Eli A., Steinberg, Stacy, Stogmann, Elisabeth, Suvisaari, Jaana, Williams, Nigel M., Witt, Stephanie H., Wormley, Brandon K., Blackwood, Douglas H.R., Bramon, Elvira, Buxbaum, Joseph D., Esko, Tõnu, Gurling, Hugh, Moran, Jennifer L., Mowry, Bryan J., Owen, Michael J., Petryshen, Tracey L., Weinberger, Daniel R., Byrne, Enda M., Abdellaoui, Abdel, Andlauer, Till F.M., Castelao, Enrique, Derks, Eske M., Foo, Jerome C., Forstner, Andreas J., Hall, Lynsey S., Homuth, Georg, Jansen, Rick, Jones, Ian, Jones, Lisa A., Kretzschmar, Warren W., McGuffin, Peter, Mihailov, Evelin, Mostafavi, Sara, Nivard, Michel G., O’Reilly, Paul F., Quiroz, Jorge A., Smith, Daniel J., Thompson, Wesley, Treutlein, Jens, Umbricht, Daniel, Wu, Yang, Zhang, Futao, Grabe, Hans J., Hayward, Caroline, Lewis, Glyn, Wray, Naomi R.
Published in Biological psychiatry (1969) (01.11.2021)

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The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls

by de Leeuw, Christiaan A., McQuillin, Andrew, Ripke, Stephan, Trzaskowski, Maciej, Agerbo, Esben, Alliey-Rodriguez, Ney, Andlauer, Till F.M., Awasthi, Swapnil, Badner, Judith A., Bækvad-Hansen, Marie, Bøen, Erlend, Castelao, Enrique, Cerrato, Felecia, Cervantes, Pablo, Colodro-Conde, Lucía, Davies, Gail, Del-Favero, Jurgen, Dumont, Ashley, Fischer, Sascha B., Foo, Jerome C., Forty, Liz, Gordon, Scott D., Green, Melissa J., Grove, Jakob, Hansen, Christine Søholm, Hansen, Thomas F., Heilbronner, Urs, van Hemert, Albert M., Hipolito, Maria, Hoffmann, Per, Holland, Dominic, Jamain, Stéphane, Jansen, Rick, Johnson, Jessica S., de Jong, Simone, Hassan Kiadeh, Farnush Farhadi, Kraft, Julia, Krogh, Jesper, Lawson, William B., Li, Yihan, Maaser, Anna, MacKinnon, Dean F., Mahon, Pamela B., Maier, Robert M., Medland, Sarah E., Mehta, Divya, Mihailov, Evelin, Montgomery, Grant W., Mullins, Niamh, Nyholt, Dale R., Ösby, Urban, Peterson, Roseann E., Pistis, Giorgio, Reinbold, Céline S., Ryu, Euijung, Schoevers, Robert, Schork, Nicholas J., Schulte, Eva C., Shehktman, Tatyana, Streit, Fabian, Thompson, Robert C., Traylor, Matthew, Vedder, Helmut, Viktorin, Alexander, Visscher, Peter M., Watson, Stanley J., Weinsheimer, Shantel Marie, Wu, Yang, Zhang, Peng, Agartz, Ingrid, Backlund, Lena, Bellivier, Frank, Blackwood, Douglas H.R., Domenici, Enrico, Fullerton, Janice M., Goes, Fernando, Hayward, Caroline, Hultman, Christina M., Jones, Ian, Kahn, René S., Kloiber, Stefan, Leboyer, Marion, Li, Qingqin S., Lucae, Susanne, Madden, Pamela A.F., Magnusson, Patrik K., Martin, Nicholas G., Mortensen, Preben Bo, Neale, Benjamin M., Nordentoft, Merete, O'Donovan, Michael C., Pato, Carlos, Pato, Michele T., Penninx, Brenda W.J. H., Posthuma, Danielle, Stefansson, Kari, Vieta, Eduard, Di Florio, Arianna, Ophoff, Roel A., Wray, Naomi R.
Published in Biological psychiatry (1969) (15.07.2020)

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A mega-analysis of genome-wide association studies for major depressive disorder

by Ripke, Stephan, Wray, Naomi R, Lewis, Cathryn M, Hamilton, Steven P, Weissman, Myrna M, Breen, Gerome, Byrne, Enda M, Blackwood, Douglas H R, Boomsma, Dorret I, Cichon, Sven, Heath, Andrew C, Holsboer, Florian, Lucae, Susanne, Madden, Pamela A F, Martin, Nicholas G, McGuffin, Peter, Muglia, Pierandrea, Noethen, Markus M, Penninx, Brenda P, Pergadia, Michele L, Potash, James B, Rietschel, Marcella, Lin, Danyu, Müller-Myhsok, Bertram, Shi, Jianxin, Steinberg, Stacy, Grabe, Hans J, Lichtenstein, Paul, Magnusson, Patrik, Perlis, Roy H, Preisig, Martin, Smoller, Jordan W, Stefansson, Kari, Uher, Rudolf, Kutalik, Zoltan, Tansey, Katherine E, Teumer, Alexander, Viktorin, Alexander, Barnes, Michael R, Bettecken, Thomas, Binder, Elisabeth B, Breuer, René, Castro, Victor M, Churchill, Susanne E, Coryell, William H, Craddock, Nick, Craig, Ian W, Czamara, Darina, De Geus, Eco J, Degenhardt, Franziska, Farmer, Anne E, Fava, Maurizio, Frank, Josef, Gainer, Vivian S, Gallagher, Patience J, Gordon, Scott D, Goryachev, Sergey, Gross, Magdalena, Guipponi, Michel, Henders, Anjali K, Herms, Stefan, Hickie, Ian B, Hoefels, Susanne, Hoogendijk, Witte, Hottenga, Jouke Jan, Iosifescu, Dan V, Ising, Marcus, Jones, Ian, Jones, Lisa, Jung-Ying, Tzeng, Knowles, James A, Kohane, Isaac S, Kohli, Martin A, Korszun, Ania, Landen, Mikael, Lawson, William B, Lewis, Glyn, Macintyre, Donald, Maier, Wolfgang, Mattheisen, Manuel, McGrath, Patrick J, McIntosh, Andrew, McLean, Alan, Middeldorp, Christel M, Middleton, Lefkos, Montgomery, Grant M, Murphy, Shawn N, Nauck, Matthias, Nolen, Willem A, Nyholt, Dale R, O'Donovan, Michael, Oskarsson, Högni, Pedersen, Nancy, Scheftner, William A, Schulz, Andrea, Schulze, Thomas G, Shyn, Stanley I, Sigurdsson, Engilbert, Slager, Susan L, Smit, Johannes H
Published in Molecular psychiatry (01.04.2013)

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Genome-wide Association for Major Depression Through Age at Onset Stratification: Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

by Power, Robert A, Tansey, Katherine E, Buttenschøn, Henriette Nørmølle, Cohen-Woods, Sarah, Bigdeli, Tim, Hall, Lynsey S, Kutalik, Zoltán, Lee, S. Hong, Ripke, Stephan, Steinberg, Stacy, Teumer, Alexander, Viktorin, Alexander, Wray, Naomi R, Arolt, Volker, Baune, Bernard T, Boomsma, Dorret I, Børglum, Anders D, Byrne, Enda M, Castelao, Enrique, Craddock, Nick, Craig, Ian W, Dannlowski, Udo, Deary, Ian J, Degenhardt, Franziska, Forstner, Andreas J, Gordon, Scott D, Grabe, Hans J, Grove, Jakob, Hamilton, Steven P, Hayward, Caroline, Heath, Andrew C, Hocking, Lynne J, Homuth, Georg, Hottenga, Jouke J, Kloiber, Stefan, Krogh, Jesper, Landén, Mikael, Lang, Maren, Levinson, Douglas F, Lichtenstein, Paul, Lucae, Susanne, MacIntyre, Donald J, Madden, Pamela, Magnusson, Patrik K.E, Martin, Nicholas G, McIntosh, Andrew M, Middeldorp, Christel M, Milaneschi, Yuri, Montgomery, Grant W, Mors, Ole, Müller-Myhsok, Bertram, Nyholt, Dale R, Oskarsson, Hogni, Owen, Michael J, Padmanabhan, Sandosh, Penninx, Brenda W.J.H, Pergadia, Michele L, Porteous, David J, Potash, James B, Preisig, Martin, Rivera, Margarita, Shi, Jianxin, Shyn, Stanley I, Sigurdsson, Engilbert, Smit, Johannes H, Smith, Blair H, Stefansson, Hreinn, Stefansson, Kari, Strohmaier, Jana, Sullivan, Patrick F, Thomson, Pippa, Thorgeirsson, Thorgeir E, Van der Auwera, Sandra, Weissman, Myrna M, Breen, Gerome, Lewis, Cathryn M
Published in Biological psychiatry (1969) (15.02.2017)

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Does Childhood Trauma Moderate Polygenic Risk for Depression? A Meta-analysis of 5765 Subjects From the Psychiatric Genomics Consortium

by Peyrot, Wouter J., Milaneschi, Yuri, Madden, Pamela A.F., Ripke, Stephan, Mullins, Niamh, Heat, Andrew C., Fisher, Helen L., Byrne, Enda M., Air, Tracy A., Wray, Naomi R., Trzaskowski, Maciej, Byrne, Enda M., Abdellaoui, Abdel, Air, Tracy M., Blackwood, Douglas H.R., Bryois, Julien, Bybjerg-Grauholm, Jonas, Cai, Na, Clarke, Toni-Kim, Crawford, Gregory E., Dolan, Conor V., Escott-Price, Valentina, Farnush, Kiadeh, Farhadi Hassan, Finucane, Hilary K., Forstner, Andreas J., Frank, Josef, Hansen, Thomas F., Herms, Stefan, Hicki, Ian B., Hoffmann, Per, Homuth, Georg, Horn, Carsten, Hottenga, Jouke-Jan, Hougaard, David M., Ising, Marcus, Jansen, Rick, Jorgenson, Eric, Kohane, Isaac S., Kretzschmar, Warren W., Li, Yihan, MacKinnon, Dean F., Maier, Wolfgang, Marchini, Jonathan, Mbarek, Hamdi, McGuffin, Peter, Medland, Sarah E., Mehta, Divya, Middeldorp, Christel M., Mihailov, Evelin, Mondimore, Francis M., Mullins, Niamh, Nauck, Matthias, Nyholt, Dale R., Oskarsson, Hogni, Painter, Jodie N., Pedersen, Marianne Giørtz, Peterson, Roseann E., Pistis, Giorgio, Qvist, Per, Rice, John P., Rivera, Margarita, Shen, Ling, Shi, Jianxin, Smit, Johannes H., Steinberg, Stacy, Strohmaier, Jana, Teumer, Alexander, Thorgeirsson, Thorgeir E., Trubetskoy, Vassily, Uitterlinden, André G., van Hemert, Albert M., Wang, Yunpeng, Webb, Bradley T., Weinsheimer, Shantel Marie, Wu, Yang, Xi, Hualin S., Yang, Jian, Arolt, Volker, de Geus, E.J.C., Hamilton, Steven P., Hayward, Caroline, Kendler, Kenneth S., Madden, Pamela A.F., Magnusson, Patrik K., Metspalu, Andres, Nöthen, Markus M., Penninx, Brenda W.J.H., Schaefer, Catherine, Schulze, Thomas G., Uher, Rudolf, Werge, Thomas, Lewis, Cathryn M., Levinson, Douglas F., Breen, Gerome, Børglum, Anders D., Sullivan, Patrick F., Breen, Gerome, Martin, Nick G., Grabe, Hans J.
Published in Biological psychiatry (1969) (15.07.2018)

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Polygenic risk prediction: why and when out-of-sample prediction R2 can exceed SNP-based heritability

by Wang, Xiaotong, Revez, Joana A., Ni, Guiyan, Adams, Mark J., McIntosh, Andrew M., Ripke, Stephan, Trzaskowski, Maciej, Byrne, Enda M., Adams, Mark J., Air, Tracy M., Andlauer, Till F.M., Bacanu, Silviu-Alin, Bryois, Julien, Bybjerg-Grauholm, Jonas, Castelao, Enrique, Clarke, Toni-Kim, Colodro-Conde, Lucía, Couvy-Duchesne, Baptiste, Craddock, Nick, Davies, Gail, Derks, Eske M., Direk, Nese, Dolan, Conor V., Kiadeh, Farnush Farhadi Hassan, Gaspar, Héléna A., Gill, Michael, Goes, Fernando S., Gordon, Scott D., Grove, Jakob, Hall, Lynsey S., Homuth, Georg, Horn, Carsten, Jones, Ian, Jones, Lisa A., Jorgenson, Eric, Kraft, Julia, Kretzschmar, Warren W., Li, Yihan, MacIntyre, Donald J., MacKinnon, Dean F., Maier, Wolfgang, Marchini, Jonathan, Mbarek, Hamdi, McGuffin, Peter, Medland, Sarah E., Mehta, Divya, Middeldorp, Christel M., Mihailov, Evelin, Mondimore, Francis M., Montgomery, Grant W., Mullins, Niamh, Ng, Bernard, Nivard, Michel G., Nyholt, Dale R., Oskarsson, Hogni, Owen, Michael J., Bøcker Pedersen, Carsten, Giørtz Pedersen, Marianne, Peterson, Roseann E., Pistis, Giorgio, Saeed Mirza, Saira, Schoevers, Robert, Schulte, Eva C., Shen, Ling, Shi, Jianxin, Shyn, Stanley I., Sinnamon, Grant C.B., Smit, Johannes H., Stefansson, Hreinn, Strohmaier, Jana, Trubetskoy, Vassily, Uitterlinden, André G., Van der Auwera, Sandra, van Hemert, Albert M., Visscher, Peter M., Wang, Yunpeng, Weinsheimer, Shantel Marie, Wellmann, Jürgen, Willemsen, Gonneke, Xi, Hualin S., Berger, Klaus, Kendler, Kenneth S., Lewis, Glyn, Li, Qingqin S., Madden, Pamela A.F., McIntosh, Andrew M., Metspalu, Andres, Mors, Ole, Nöthen, Markus M., O'Donovan, Michael C., Paciga, Sara A., Pedersen, Nancy L., Porteous, David J., Potash, James B., Rietschel, Marcella, Smoller, Jordan W., Stefansson, Kari, Tiemeier, Henning, Völzke, Henry, Weissman, Myrna M.
Published in American journal of human genetics (06.07.2023)

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Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression

by Hanscombe, Ken B., Euesden, Jack, Choi, Shing Wan, Binder, Elisabeth B., Blackwood, Douglas H.R., Colodro-Conde, Lucía, Dannlowski, Udo, Dunn, Erin C., de Geus, Eco J.C., Grabe, Hans J., Jones, Ian, Knowles, James A., Kutalik, Zoltán, Müller-Myhsok, Bertram, Penninx, Brenda W.J.H., Shyn, Stanley I., Sullivan, Patrick F., Tiemeier, Henning, Weissman, Myrna M., Ripke, Stephan, Byrne, Enda M., Bækvad-Hansen, Marie, Beekman, Aartjan T.F., Buttenschøn, Henriette N., Bybjerg-Grauholm, Jonas, Castelao, Enrique, Christensen, Jane Hvarregaard, Couvy-Duchesne, Baptiste, Craddock, Nick, Davies, Gail, Derks, Eske M., Dolan, Conor V., Eley, Thalia C., Gaspar, Héléna A., Gill, Michael, Goes, Fernando S., Gordon, Scott D., Grove, Jakob, Hickie, Ian B., Hottenga, Jouke-Jan, Jansen, Rick, Jones, Ian, Jorgenson, Eric, Kraft, Julia, Li, Yihan, Lind, Penelope A., MacIntyre, Donald J., Mbarek, Hamdi, McGrath, Patrick, Mehta, Divya, Milaneschi, Yuri, Mullins, Niamh, Nivard, Michel G., Nyholt, Dale R., O'Reilly, Paul F., Oskarsson, Hogni, Pedersen, Carsten Bøcker, Pedersen, Marianne Giørtz, Peterson, Roseann E., Pistis, Giorgio, Rivera, Margarita, Mirza, Saira Saeed, Schoevers, Robert, Schulte, Eva C., Shen, Ling, Shi, Jianxin, Sinnamon, Grant C.B., Smit, Johannes H., Steinberg, Stacy, Tansey, Katherine E., Teumer, Alexander, Van der Auwera, Sandra, Wang, Yunpeng, Weinsheimer, Shantel Marie, Willemsen, Gonneke, Wu, Yang, Yang, Jian, de Geus, EJC, DePaulo, J. Raymond, Esko, Tõnu, Grabe, Hans J., Hamilton, Steven P., Hayward, Caroline, Heath, Andrew C., Kendler, Kenneth S., Lewis, Glyn, Magnusson, Patrik K., Nordentoft, Merete, Pedersen, Nancy L., Penninx, Brenda W.J.H., Porteous, David J., Potash, James B., Schaefer, Catherine, Tiemeier, Henning, Werge, Thomas, Levinson, Douglas F., Breen, Gerome, Sullivan, Patrick F., O'Reilly, Paul F., Lewis, Cathryn M.
Published in Biological psychiatry (1969) (01.03.2020)

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Association of Whole-Genome and NETRIN1 Signaling Pathway–Derived Polygenic Risk Scores for Major Depressive Disorder and White Matter Microstructure in the UK Biobank

by Barbu, Miruna C., Zeng, Yanni, Clarke, Toni-Kim, Ripke, Stephan, Mattheisen, Manuel, Byrne, Enda M., Adams, Mark J., Andlauer, Till F.M., Bacanu, Silviu-Alin, Bækvad-Hansen, Marie, Beekman, Aartjan T.F., Bigdeli, Tim B., Blackwood, Douglas H.R., Buttenschøn, Henriette N., Bybjerg-Grauholm, Jonas, Castelao, Enrique, Clarke, Toni-Kim, Crawford, Gregory E., Davies, Gail, Deary, Ian J., Dolan, Conor V., Hassan Kiadeh, Farnush Farhadi, Finucane, Hilary K., Gaspar, Héléna A., Gill, Michael, Goes, Fernando S., Gordon, Scott D., Grove, Jakob, Homuth, Georg, Hougaard, David M., Knowles, James A., Kutalik, Zoltán, Maier, Robert M., Maier, Wolfgang, McGrath, Patrick, McGuffin, Peter, Mehta, Divya, Middeldorp, Christel M., Milaneschi, Yuri, Milani, Lili, Montgomery, Grant W., Mostafavi, Sara, O'Reilly, Paul F., Oskarsson, Hogni, Owen, Michael J., Pedersen, Carsten Bøcker, Pedersen, Marianne Giørtz, Pettersson, Erik, Posthuma, Danielle, Mirza, Saira Saeed, Schoevers, Robert, Schulte, Eva C., Shyn, Stanley I., Sinnamon, Grant C.B., Smit, Johannes H., Stefansson, Hreinn, Tansey, Katherine E., Thompson, Wesley, Trubetskoy, Vassily, Umbricht, Daniel, Van der Auwera, Sandra, Viktorin, Alexander, Visscher, Peter M., Wellmann, Jürgen, Willemsen, Gonneke, Baune, Bernhard T., Berger, Klaus, Boomsma, Dorret I., Domenici, Enrico, Esko, Tõnu, Kloiber, Stefan, Li, Qingqin S., Madden, Pamela A.F., Martin, Nicholas G., McIntosh, Andrew M., Mors, Ole, Müller-Myhsok, Bertram, Nordentoft, Merete, Nöthen, Markus M., O'Donovan, Michael C., Paciga, Sara A., Pedersen, Nancy L., Porteous, David J., Rietschel, Marcella, Smoller, Jordan W., Stefansson, Kari, Tiemeier, Henning, Völzke, Henry, Weissman, Myrna M., Alipanahi, Babak, Bryc, Katarzyna, Huber, Karen E., Litterman, Nadia K., Mountain, Joanna L., Pitts, Steven J., Shelton, Janie F., Tian, Chao, Tung, Joyce Y., Vacic, Vladimir, Whalley, Heather C.
Published in Biological psychiatry : cognitive neuroscience and neuroimaging (01.01.2019)

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