RADX Promotes Genome Stability and Modulates Chemosensitivity by Regulating RAD51 at Replication Forks
Dungrawala, Huzefa, Bhat, Kamakoti P., Le Meur, Rémy, Chazin, Walter J., Ding, Xia, Sharan, Shyam K., Wessel, Sarah R., Sathe, Aditya A., Zhao, Runxiang, Cortez, David
Published in Molecular cell (03.08.2017)
Published in Molecular cell (03.08.2017)
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Journal Article
Replication fork stability confers chemoresistance in BRCA-deficient cells
Ray Chaudhuri, Arnab, Callen, Elsa, Ding, Xia, Gogola, Ewa, Duarte, Alexandra A, Lee, Ji-Eun, Wong, Nancy, Lafarga, Vanessa, Calvo, Jennifer A, Panzarino, Nicholas J, John, Sam, Day, Amanda, Crespo, Anna Vidal, Shen, Binghui, Starnes, Linda M, de Ruiter, Julian R, Daniel, Jeremy A, Konstantinopoulos, Panagiotis A, Cortez, David, Cantor, Sharon B, Fernandez-Capetillo, Oscar, Ge, Kai, Jonkers, Jos, Rottenberg, Sven, Sharan, Shyam K, Nussenzweig, André
Published in Nature (London) (21.07.2016)
Published in Nature (London) (21.07.2016)
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Recombineering: a homologous recombination-based method of genetic engineering
Sharan, Shyam K, Court, Donald L, Thomason, Lynn C, Kuznetsov, Sergey G
Published in Nature protocols (01.01.2009)
Published in Nature protocols (01.01.2009)
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Journal Article
Genetically engineered mouse models for hereditary cancer syndromes
Biswas, Kajal, Mohammed, Altaf, Sharan, Shyam K., Shoemaker, Robert H.
Published in Cancer science (01.05.2023)
Published in Cancer science (01.05.2023)
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Journal Article
Identification PMS1 and PMS2 as potential meiotic substrates of CDK2 activity
Palmer, Nathan, Talib, S Zakiah A, Goh, Christine M F, Biswas, Kajal, Sharan, Shyam K, Kaldis, Philipp
Published in PloS one (23.03.2023)
Published in PloS one (23.03.2023)
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Coiled-Coil Domain: Uncoiling Tumor Suppression by BRCA1
Mishra, Arun P, Sahu, Sounak, Sharan, Shyam K
Published in Cancer research (Chicago, Ill.) (15.12.2021)
Published in Cancer research (Chicago, Ill.) (15.12.2021)
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Journal Article
Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2
Hartford, Suzanne A, Chittela, Rajanikant, Ding, Xia, Vyas, Aradhana, Martin, Betty, Burkett, Sandra, Haines, Diana C, Southon, Eileen, Tessarollo, Lino, Sharan, Shyam K
Published in PLoS genetics (04.08.2016)
Published in PLoS genetics (04.08.2016)
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Journal Article
Variants of uncertain clinical significance in hereditary breast and ovarian cancer genes: best practices in functional analysis for clinical annotation
Monteiro, Alvaro N, Bouwman, Peter, Kousholt, Arne N, Eccles, Diana M, Millot, Gael A, Masson, Jean-Yves, Schmidt, Marjanka K, Sharan, Shyam K, Scully, Ralph, Wiesmüller, Lisa, Couch, Fergus, Vreeswijk, Maaike P G
Published in Journal of medical genetics (01.08.2020)
Published in Journal of medical genetics (01.08.2020)
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microRNA-155 positively regulates glucose metabolism via PIK3R1-FOXO3a-cMYC axis in breast cancer
Kim, Sinae, Lee, Eunji, Jung, Jaeyun, Lee, Jong Won, Kim, Hee Jung, Kim, Jisun, Yoo, Hyun Ju, Lee, Hee Jin, Chae, Sun Young, Jeon, Sang Min, Son, Byung Ho, Gong, Gyungyup, Sharan, Shyam K, Chang, Suhwan
Published in Oncogene (01.05.2018)
Published in Oncogene (01.05.2018)
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Bypass of premature stop codons and generation of functional BRCA2 by exon skipping
Stauffer, Stacey, Biswas, Kajal, Sharan, Shyam K
Published in Journal of human genetics (01.09.2020)
Published in Journal of human genetics (01.09.2020)
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Journal Article
Intragenic DNA methylation and BORIS-mediated cancer-specific splicing contribute to the Warburg effect
Singh, Smriti, Narayanan, Sathiya Pandi, Biswas, Kajal, Gupta, Amit, Ahuja, Neha, Yadav, Sandhya, Panday, Rajendra Kumar, Samaiya, Atul, Sharan, Shyam K., Shukla, Sanjeev
Published in Proceedings of the National Academy of Sciences - PNAS (24.10.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (24.10.2017)
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Antibacterial Use in Admitted Patients of a Super Speciality Hospital in Western India
Shyam, Sharan, Jaiswal, Sanjay
Published in Journal of pharmacology & pharmacotherapeutics (01.01.2021)
Published in Journal of pharmacology & pharmacotherapeutics (01.01.2021)
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Journal Article
WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells
Datta, Arindam, Biswas, Kajal, Sommers, Joshua A, Thompson, Haley, Awate, Sanket, Nicolae, Claudia M, Thakar, Tanay, Moldovan, George-Lucian, Shoemaker, Robert H, Sharan, Shyam K, Brosh, Jr, Robert M
Published in Nature communications (12.11.2021)
Published in Nature communications (12.11.2021)
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Journal Article
Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies
Ding, Xia, Ray Chaudhuri, Arnab, Callen, Elsa, Pang, Yan, Biswas, Kajal, Klarmann, Kimberly D, Martin, Betty K, Burkett, Sandra, Cleveland, Linda, Stauffer, Stacey, Sullivan, Teresa, Dewan, Aashish, Marks, Hanna, Tubbs, Anthony T, Wong, Nancy, Buehler, Eugen, Akagi, Keiko, Martin, Scott E, Keller, Jonathan R, Nussenzweig, André, Sharan, Shyam K
Published in Nature communications (08.08.2016)
Published in Nature communications (08.08.2016)
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The Indenoisoquinoline TOP1 Inhibitors Selectively Target Homologous Recombination-Deficient and Schlafen 11-Positive Cancer Cells and Synergize with Olaparib
Marzi, Laetitia, Szabova, Ludmila, Gordon, Melanie, Weaver Ohler, Zoe, Sharan, Shyam K, Beshiri, Michael L, Etemadi, Moudjib, Murai, Junko, Kelly, Kathleen, Pommier, Yves
Published in Clinical cancer research (15.10.2019)
Published in Clinical cancer research (15.10.2019)
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Journal Article
Interferon restores replication fork stability and cell viability in BRCA-defective cells via ISG15
Moro, Ramona N, Biswas, Uddipta, Kharat, Suhas S, Duzanic, Filip D, Das, Prosun, Stavrou, Maria, Raso, Maria C, Freire, Raimundo, Chaudhuri, Arnab Ray, Sharan, Shyam K, Penengo, Lorenza
Published in Nature communications (02.10.2023)
Published in Nature communications (02.10.2023)
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Journal Article
The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation
Xu, Xiaoping, Ni, Kai, He, Yafeng, Ren, Jianke, Sun, Chongkui, Liu, Yie, Aladjem, Mirit I., Burkett, Sandra, Finney, Richard, Ding, Xia, Sharan, Shyam K., Muegge, Kathrin
Published in Nature communications (10.06.2021)
Published in Nature communications (10.06.2021)
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Journal Article
Degradation of 5hmC-marked stalled replication forks by APE1 causes genomic instability
Kharat, Suhas S, Ding, Xia, Swaminathan, Divya, Suresh, Akshey, Singh, Manish, Sengodan, Satheesh K, Burkett, Sandra, Marks, Hanna, Pamala, Chinmayi, He, Yafeng, Fox, Stephen D, Buehler, Eugen C, Muegge, Kathrin, Martin, Scott E, Sharan, Shyam K
Published in Science signaling (18.08.2020)
Published in Science signaling (18.08.2020)
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