Targeting vascular (endothelial) dysfunction
Daiber, Andreas, Steven, Sebastian, Weber, Alina, Shuvaev, Vladimir V., Muzykantov, Vladimir R., Laher, Ismail, Li, Huige, Lamas, Santiago, Münzel, Thomas
Published in British journal of pharmacology (01.06.2017)
Published in British journal of pharmacology (01.06.2017)
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Journal Article
PECAM-1 directed re-targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E-mediated uptake
Parhiz, Hamideh, Shuvaev, Vladimir V., Pardi, Norbert, Khoshnejad, Makan, Kiseleva, Raisa Yu, Brenner, Jacob S., Uhler, Thomas, Tuyishime, Steven, Mui, Barbara L., Tam, Ying K., Madden, Thomas D., Hope, Michael J., Weissman, Drew, Muzykantov, Vladimir R.
Published in Journal of controlled release (10.12.2018)
Published in Journal of controlled release (10.12.2018)
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Journal Article
Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood–brain barrier
Marcos-Contreras, Oscar A., Greineder, Colin F., Kiseleva, Raisa Yu, Parhiz, Hamideh, Walsh, Landis R., Zuluaga-Ramirez, Viviana, Myerson, Jacob W., Hood, Elizabeth D., Villa, Carlos H., Tombacz, Istvan, Pardi, Norbert, Seliga, Alecia, Mui, Barbara L., Tam, Ying K., Glassman, Patrick M., Shuvaev, Vladimir V., Nong, Jia, Brenner, Jacob S., Khoshnejad, Makan, Madden, Tom, Weissmann, Drew, Persidsky, Yuri, Muzykantov, Vladimir R.
Published in Proceedings of the National Academy of Sciences - PNAS (18.02.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (18.02.2020)
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Journal Article
Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE)
Parhiz, Hamideh, Brenner, Jacob S., Patel, Priyal N., Papp, Tyler E., Shahnawaz, Hamna, Li, Qin, Shi, Ruiqi, Zamora, Marco E., Yadegari, Amir, Marcos-Contreras, Oscar A., Natesan, Ambika, Pardi, Norbert, Shuvaev, Vladimir V., Kiseleva, Raisa, Myerson, Jacob W., Uhler, Thomas, Riley, Rachel S., Han, Xuexiang, Mitchell, Michael J., Lam, Kieu, Heyes, James, Weissman, Drew, Muzykantov, Vladimir R.
Published in Journal of controlled release (01.04.2022)
Published in Journal of controlled release (01.04.2022)
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Journal Article
Polytopic ligand directed self-assembly-polymetallic [n x n] grids versus non-grid oligomers
Dawe, Louise N, Shuvaev, Konstantin V, Thompson, Laurence K
Published in Chemical Society reviews (01.01.2009)
Published in Chemical Society reviews (01.01.2009)
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Journal Article
Acute administration of catalase targeted to ICAM-1 attenuates neuropathology in experimental traumatic brain injury
Lutton, Evan M., Razmpour, Roshanak, Andrews, Allison M., Cannella, Lee Anne, Son, Young-Jin, Shuvaev, Vladimir V., Muzykantov, Vladimir R., Ramirez, Servio H.
Published in Scientific reports (19.06.2017)
Published in Scientific reports (19.06.2017)
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Journal Article
Up-regulation of NADPH oxidase-mediated redox signaling contributes to the loss of barrier function in KRIT1 deficient endothelium
Goitre, Luca, DiStefano, Peter V., Moglia, Andrea, Nobiletti, Nicholas, Baldini, Eva, Trabalzini, Lorenza, Keubel, Julie, Trapani, Eliana, Shuvaev, Vladimir V., Muzykantov, Vladimir R., Sarelius, Ingrid H., Retta, Saverio Francesco, Glading, Angela J.
Published in Scientific reports (15.08.2017)
Published in Scientific reports (15.08.2017)
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Journal Article
Icam-1 targeted nanogels loaded with dexamethasone alleviate pulmonary inflammation
Ferrer, M Carme Coll, Shuvaev, Vladimir V, Zern, Blaine J, Composto, Russell J, Muzykantov, Vladimir R, Eckmann, David M
Published in PloS one (14.07.2014)
Published in PloS one (14.07.2014)
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Journal Article
Endothelial Targeting of Antibody-Decorated Polymeric Filomicelles
Shuvaev, Vladimir V, Ilies, Marc A, Simone, Eric, Zaitsev, Sergei, Kim, Younghoon, Cai, Shenshen, Mahmud, Abdullah, Dziubla, Thomas, Muro, Silvia, Discher, Dennis E, Muzykantov, Vladimir R
Published in ACS nano (27.09.2011)
Published in ACS nano (27.09.2011)
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Journal Article
Targeted modulation of reactive oxygen species in the vascular endothelium
Shuvaev, Vladimir V., Muzykantov, Vladimir R.
Published in Journal of controlled release (15.07.2011)
Published in Journal of controlled release (15.07.2011)
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Journal Article
Conference Proceeding
Copper Oxide Nanoparticle-Induced Acute Inflammatory Response and Injury in Murine Lung Is Ameliorated by Synthetic Secoisolariciresinol Diglucoside (LGM2605)
Pietrofesa, Ralph A, Park, Kyewon, Mishra, Om P, Johnson-McDaniel, Darrah, Myerson, Jacob W, Shuvaev, Vladimir V, Arguiri, Evguenia, Chatterjee, Shampa, Moorthy, Ganesh S, Zuppa, Athena, Hwang, Wei-Ting, Christofidou-Solomidou, Melpo
Published in International journal of molecular sciences (31.08.2021)
Published in International journal of molecular sciences (31.08.2021)
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Journal Article
Superoxide Dismutase-Loaded Porous Polymersomes as Highly Efficient Antioxidants for Treating Neuropathic Pain
Kartha, Sonia, Yan, Lesan, Weisshaar, Christine L, Ita, Meagan E, Shuvaev, Vladimir V, Muzykantov, Vladimir R, Tsourkas, Andrew, Winkelstein, Beth A, Cheng, Zhiliang
Published in Advanced healthcare materials (01.09.2017)
Published in Advanced healthcare materials (01.09.2017)
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Journal Article
Anti-inflammatory effect of targeted delivery of SOD to endothelium: mechanism, synergism with NO donors and protective effects in vitro and in vivo
Shuvaev, Vladimir V, Han, Jingyan, Tliba, Samira, Arguiri, Evguenia, Christofidou-Solomidou, Melpo, Ramirez, Servio H, Dykstra, Holly, Persidsky, Yuri, Atochin, Dmitriy N, Huang, Paul L, Muzykantov, Vladimir R
Published in PloS one (11.10.2013)
Published in PloS one (11.10.2013)
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Journal Article
Endothelial Targeted Strategies to Combat Oxidative Stress: Improving Outcomes in Traumatic Brain Injury
Lutton, Evan M, Farney, S Katie, Andrews, Allison M, Shuvaev, Vladimir V, Chuang, Gwo-Yu, Muzykantov, Vladimir R, Ramirez, Servio H
Published in Frontiers in neurology (06.06.2019)
Published in Frontiers in neurology (06.06.2019)
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Journal Article
Bivalent engagement of endothelial surface antigens is critical to prolonged surface targeting and protein delivery in vivo
Kiseleva, R Yu, Glassman, P G, LeForte, K M, Walsh, L R, Villa, C H, Shuvaev, V V, Myerson, J W, Aprelev, P A, Marcos-Contreras, O A, Muzykantov, V R, Greineder, C F
Published in The FASEB journal (01.09.2020)
Published in The FASEB journal (01.09.2020)
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Journal Article
Glycation vs. glycosylation: a tale of two different chemistries and biology in Alzheimer’s disease
Taniguchi, Naoyuki, Takahashi, Motoko, Kizuka, Yasuhiko, Kitazume, Shinobu, Shuvaev, Vladimir V., Ookawara, Tomomi, Furuta, Akiko
Published in Glycoconjugate journal (01.08.2016)
Published in Glycoconjugate journal (01.08.2016)
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Journal Article
Physiologically based modeling of LNP-mediated delivery of mRNA in the vascular system
Parhiz, Hamideh, Shuvaev, Vladimir V., Li, Qin, Papp, Tyler E., Akyianu, Awurama A., Shi, Ruiqi, Yadegari, Amir, Shahnawaz, Hamna, Semple, Sean C., Mui, Barbara L., Weissman, Drew, Muzykantov, Vladimir R., Glassman, Patrick M.
Published in Molecular therapy. Nucleic acids (11.06.2024)
Published in Molecular therapy. Nucleic acids (11.06.2024)
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Journal Article