Δ(9)-Tetrahydrocannabinol acts as a partial agonist/antagonist in mice
Paronis, Carol A, Nikas, Spyros P, Shukla, Vidyanand G, Makriyannis, Alexandros
Published in Behavioural pharmacology (01.12.2012)
Published in Behavioural pharmacology (01.12.2012)
Get more information
Journal Article
Piperidine and piperazine inhibitors of fatty acid amide hydrolase targeting excitotoxic pathology
Lamani, Manjunath, Malamas, Michael S., Farah, Shrouq I., Shukla, Vidyanand G., Almeida, Michael F., Weerts, Catherine M., Anderson, Joseph, Wood, JodiAnne T., Farizatto, Karen L.G., Bahr, Ben A., Makriyannis, Alexandros
Published in Bioorganic & medicinal chemistry (01.12.2019)
Published in Bioorganic & medicinal chemistry (01.12.2019)
Get full text
Journal Article
Cannabinoid CB1 Discrimination: Effects of Endocannabinoids and Catabolic Enzyme Inhibitors
Leonard, Michael Z., Alapafuja, Shakiru O., Ji, Lipin, Shukla, Vidyanand G., Liu, Yingpeng, Nikas, Spyros P., Makriyannis, Alexandros, Bergman, Jack, Kangas, Brian D.
Published in The Journal of pharmacology and experimental therapeutics (01.12.2017)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2017)
Get full text
Journal Article
Cannabinoid CB 1 Discrimination: Effects of Endocannabinoids and Catabolic Enzyme Inhibitors
Leonard, Michael Z, Alapafuja, Shakiru O, Ji, Lipin, Shukla, Vidyanand G, Liu, Yingpeng, Nikas, Spyros P, Makriyannis, Alexandros, Bergman, Jack, Kangas, Brian D
Published in The Journal of pharmacology and experimental therapeutics (01.12.2017)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2017)
Get full text
Journal Article
Sulfonyl Fluoride Inhibitors of Fatty Acid Amide Hydrolase
Alapafuja, Shakiru O, Nikas, Spyros P, Bharathan, Indu T, Shukla, Vidyanand G, Nasr, Mahmoud L, Bowman, Anna L, Zvonok, Nikolai, Li, Jing, Shi, Xiaomeng, Engen, John R, Makriyannis, Alexandros
Published in Journal of medicinal chemistry (26.11.2012)
Published in Journal of medicinal chemistry (26.11.2012)
Get full text
Journal Article
Cannabinoid withdrawal in mice: inverse agonist vs neutral antagonist
Tai, Sherrica, Nikas, Spyros P., Shukla, Vidyanand G., Vemuri, Kiran, Makriyannis, Alexandros, Järbe, Torbjörn U. C.
Published in Psychopharmacology (01.08.2015)
Published in Psychopharmacology (01.08.2015)
Get full text
Journal Article
C3-Heteroaroyl cannabinoids as photolabeling ligands for the CB2 cannabinoid receptor
Dixon, Darryl D., Tius, Marcus A., Thakur, Ganesh A., Zhou, Han, Bowman, Anna L., Shukla, Vidyanand G., Peng, Yan, Makriyannis, Alexandros
Published in Bioorganic & medicinal chemistry letters (15.08.2012)
Published in Bioorganic & medicinal chemistry letters (15.08.2012)
Get full text
Journal Article
Inhibitor of Endocannabinoid Deactivation Protects Against In Vitro and In Vivo Neurotoxic Effects of Paraoxon
Farizatto, Karen L. G., McEwan, Sara A., Naidoo, Vinogran, Nikas, Spyros P., Shukla, Vidyanand G., Almeida, Michael F., Byrd, Aaron, Romine, Heather, Karanian, David A., Makriyannis, Alexandros, Bahr, Ben A.
Published in Journal of molecular neuroscience (01.09.2017)
Published in Journal of molecular neuroscience (01.09.2017)
Get full text
Journal Article
Comparisons of Δ9-Tetrahydrocannabinol and Anandamide on a Battery of Cognition-Related Behavior in Nonhuman Primates
Kangas, Brian D, Leonard, Michael Z, Shukla, Vidyanand G, Alapafuja, Shakiru O, Nikas, Spyros P, Makriyannis, Alexandros, Bergman, Jack
Published in The Journal of pharmacology and experimental therapeutics (01.04.2016)
Published in The Journal of pharmacology and experimental therapeutics (01.04.2016)
Get full text
Journal Article
Novel 1′,1′-Chain Substituted Hexahydrocannabinols: 9β-Hydroxy-3-(1-hexyl-cyclobut-1-yl)-hexahydrocannabinol (AM2389) a Highly Potent Cannabinoid Receptor 1 (CB1) Agonist
Nikas, Spyros P, Alapafuja, Shakiru O, Papanastasiou, Ioannis, Paronis, Carol A, Shukla, Vidyanand G, Papahatjis, Demetris P, Bowman, Anna L, Halikhedkar, Aneetha, Han, Xiuwen, Makriyannis, Alexandros
Published in Journal of medicinal chemistry (14.10.2010)
Published in Journal of medicinal chemistry (14.10.2010)
Get full text
Journal Article
AM2389, a high-affinity, in vivo potent CB1-receptor-selective cannabinergic ligand as evidenced by drug discrimination in rats and hypothermia testing in mice
Järbe, Torbjörn U. C., Tai, Sherrica, LeMay, Brian J., Nikas, Spyros P., Shukla, Vidyanand G., Zvonok, Alexander, Makriyannis, Alexandros
Published in Psychopharmacologia (01.03.2012)
Published in Psychopharmacologia (01.03.2012)
Get full text
Journal Article
Molecular-Interaction and Signaling Profiles of AM3677, a Novel Covalent Agonist Selective for the Cannabinoid 1 Receptor
Janero, David R, Yaddanapudi, Suma, Zvonok, Nikolai, Subramanian, Kumar V, Shukla, Vidyanand G, Stahl, Edward, Zhou, Lei, Hurst, Dow, Wager-Miller, James, Bohn, Laura M, Reggio, Patricia H, Mackie, Ken, Makriyannis, Alexandros
Published in ACS chemical neuroscience (19.08.2015)
Published in ACS chemical neuroscience (19.08.2015)
Get full text
Journal Article
Cannabinoid Discrimination and Antagonism by CB1 Neutral and Inverse Agonist Antagonists
Kangas, Brian D., Delatte, Marcus S., Vemuri, V. Kiran, Thakur, Ganesh A., Nikas, Spyridon P., Subramanian, Kumara V., Shukla, Vidyanand G., Makriyannis, Alexandros, Bergman, Jack
Published in The Journal of pharmacology and experimental therapeutics (01.03.2013)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2013)
Get full text
Journal Article
Synthesis and evaluation of potent and selective MGL inhibitors as a glaucoma treatment
Alapafuja, Shakiru O., Malamas, Michael S., Shukla, Vidyanand, Zvonok, Alexander, Miller, Sally, Daily, Laura, Rajarshi, Girija, Miyabe, Christina Yume, Chandrashekhar, Honrao, Wood, JodiAnne, Tyukhtenko, Sergiy, Straiker, Alex, Makriyannis, Alexandros
Published in Bioorganic & medicinal chemistry (01.01.2019)
Published in Bioorganic & medicinal chemistry (01.01.2019)
Get full text
Journal Article
Novel 1 ',1 '-Chain Substituted Hexahydrocannabinols: 9/beta-1-Hydroxy-3-(1-hexyl-cyclobut-l-yl)hexahydrocannabinol (AM2389) a Highly Potent Cannabinoid Receptor 1 (CB1) Agonist
Nikas, Spyros P., Alapafuja, Shakiru O., Papanastasiou, Ioannis, Paronis, Carole A., Shukla, Vidyanand G., Papahatjis, Demetris P., Bowman, Anna L., Halikhedkar, Aneetha, Han, Xiuwen, Makriyannis, Alexandros
Published in Journal of medicinal chemistry (14.10.2010)
Published in Journal of medicinal chemistry (14.10.2010)
Get full text
Journal Article
Equipotent Inhibition of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase – Dual Targets of the Endocannabinoid System to Protect against Seizure Pathology
Naidoo, Vinogran, Karanian, David A., Vadivel, Subramanian K., Locklear, Johnathan R., Wood, JodiAnne T., Nasr, Mahmoud, Quizon, Pamela Marie P., Graves, Emily E., Shukla, Vidyanand, Makriyannis, Alexandros, Bahr, Ben A.
Published in Neurotherapeutics (01.10.2012)
Published in Neurotherapeutics (01.10.2012)
Get full text
Journal Article
Cannabinoid Discrimination and Antagonism by CB 1 Neutral and Inverse Agonist Antagonists
Kangas, Brian D., Delatte, Marcus S., Vemuri, V. Kiran, Thakur, Ganesh A., Nikas, Spyridon P., Subramanian, Kumara V., Shukla, Vidyanand G., Makriyannis, Alexandros, Bergman, Jack
Published in The Journal of pharmacology and experimental therapeutics (01.03.2013)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2013)
Get full text
Journal Article
AM2389, a high-affinity, in vivo potent C[B.sub.1]-receptor-selective cannabinergic ligand as evidenced by drug discrimination in rats and hypothermia testing in mice
Jarbe, Torbjorn U.C, Tai, Sherrica, LeMay, Brian J, Nikas, Spyros P, Shukla, Vidyanand G, Zvonok, Alexander, Makriyannis, Alexandros
Published in Psychopharmacology (15.03.2012)
Published in Psychopharmacology (15.03.2012)
Get full text
Journal Article