Discovery of 4-(5-Methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a Novel alpha 7 Nicotinic Acetylcholine Receptor Agonist for the Treatment of Cognitive Disorders in Schizophrenia: Synthesis, SAR Development, and in Vivo Efficacy in Cognition Models
O'Donnell, Christopher J., Rogers, Bruce N., Bronk, Brian S., Bryce, Dianne K., Coe, Jotham W., Cook, Karen K., Duplantier, Allen J., Evrard, Edelweiss, Hajos, Mihaly, Hoffmann, William E., Hurst, Raymond S., Maklad, Noha, Mather, Robert J., McLean, Stafford, Nedza, Frank M., O'Neill, Brian T., Peng, Langu, Qian, Weimin, Rottas, Melinda M., Sands, Steven B., Schmidt, Anne W., Shrikhande, Alka V., Spracklin, Douglas K., Wong, Diane F., Zhang, Andy, Zhang, Lei
Published in Journal of medicinal chemistry (11.02.2010)
Published in Journal of medicinal chemistry (11.02.2010)
Get full text
Journal Article
Discovery of 4-(5-Methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a Novel α7 Nicotinic Acetylcholine Receptor Agonist for the Treatment of Cognitive Disorders in Schizophrenia: Synthesis, SAR Development, and in Vivo Efficacy in Cognition Models
O’Donnell, Christopher J, Rogers, Bruce N, Bronk, Brian S, Bryce, Dianne K, Coe, Jotham W, Cook, Karen K, Duplantier, Allen J, Evrard, Edelweiss, Hajós, Mihaly, Hoffmann, William E, Hurst, Raymond S, Maklad, Noha, Mather, Robert J, McLean, Stafford, Nedza, Frank M, O’Neill, Brian T, Peng, Langu, Qian, Weimin, Rottas, Melinda M, Sands, Steven B, Schmidt, Anne W, Shrikhande, Alka V, Spracklin, Douglas K, Wong, Diane F, Zhang, Andy, Zhang, Lei
Published in Journal of medicinal chemistry (11.02.2010)
Published in Journal of medicinal chemistry (11.02.2010)
Get full text
Journal Article