Therapeutic targeting of PFKFB3 with a novel glycolytic inhibitor PFK158 promotes lipophagy and chemosensitivity in gynecologic cancers
Mondal, Susmita, Roy, Debarshi, Sarkar Bhattacharya, Sayantani, Jin, Ling, Jung, Deokbeom, Zhang, Song, Kalogera, Eleftheria, Staub, Julie, Wang, Yaxian, Xuyang, Wen, Khurana, Ashwani, Chien, Jeremey, Telang, Sucheta, Chesney, Jason, Tapolsky, Gilles, Petras, Dzeja, Shridhar, Viji
Published in International journal of cancer (01.01.2019)
Published in International journal of cancer (01.01.2019)
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Journal Article
Quinacrine upregulates p21/p27 independent of p53 through autophagy-mediated downregulation of p62-Skp2 axis in ovarian cancer
Jung, DeokBeom, Khurana, Ashwani, Roy, Debarshi, Kalogera, Eleftheria, Bakkum-Gamez, Jamie, Chien, Jeremy, Shridhar, Viji
Published in Scientific reports (06.02.2018)
Published in Scientific reports (06.02.2018)
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Journal Article
Nanoceria: a rare-earth nanoparticle as a novel anti-angiogenic therapeutic agent in ovarian cancer
Giri, Shailendra, Karakoti, Ajay, Graham, Rondell P, Maguire, Jacie L, Reilly, Christopher M, Seal, Sudipta, Rattan, Ramandeep, Shridhar, Viji
Published in PloS one (31.01.2013)
Published in PloS one (31.01.2013)
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Journal Article
Inhibition of PFKFB3 induces cell death and synergistically enhances chemosensitivity in endometrial cancer
Xiao, Yinan, Jin, Ling, Deng, Chaolin, Guan, Ye, Kalogera, Eleftheria, Ray, Upasana, Thirusangu, Prabhu, Staub, Julie, Sarkar Bhattacharya, Sayantani, Xu, Haotian, Fang, Xiaoling, Shridhar, Viji
Published in Oncogene (25.02.2021)
Published in Oncogene (25.02.2021)
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Journal Article
The Role of Heparanase and Sulfatases in the Modification of Heparan Sulfate Proteoglycans within the Tumor Microenvironment and Opportunities for Novel Cancer Therapeutics
Hammond, Edward, Khurana, Ashwani, Shridhar, Viji, Dredge, Keith
Published in Frontiers in oncology (01.01.2014)
Published in Frontiers in oncology (01.01.2014)
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Journal Article
Bevacizumab May Differentially Improve Ovarian Cancer Outcome in Patients with Proliferative and Mesenchymal Molecular Subtypes
Kommoss, Stefan, Winterhoff, Boris, Oberg, Ann L, Konecny, Gottfried E, Wang, Chen, Riska, Shaun M, Fan, Jian-Bing, Maurer, Matthew J, April, Craig, Shridhar, Viji, Kommoss, Friedrich, du Bois, Andreas, Hilpert, Felix, Mahner, Sven, Baumann, Klaus, Schroeder, Willibald, Burges, Alexander, Canzler, Ulrich, Chien, Jeremy, Embleton, Andrew C, Parmar, Mahesh, Kaplan, Richard, Perren, Timothy, Hartmann, Lynn C, Goode, Ellen L, Dowdy, Sean C, Pfisterer, Jacobus
Published in Clinical cancer research (15.07.2017)
Published in Clinical cancer research (15.07.2017)
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Journal Article
HtrA serine proteases as potential therapeutic targets in cancer
Chien, Jeremy, Campioni, Mara, Shridhar, Viji, Baldi, Alfonso
Published in Current cancer drug targets (01.06.2009)
Published in Current cancer drug targets (01.06.2009)
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Journal Article
Quinacrine-Induced Autophagy in Ovarian Cancer Triggers Cathepsin-L Mediated Lysosomal/Mitochondrial Membrane Permeabilization and Cell Death
Thirusangu, Prabhu, Pathoulas, Christopher L, Ray, Upasana, Xiao, Yinan, Staub, Julie, Jin, Ling, Khurana, Ashwani, Shridhar, Viji
Published in Cancers (21.04.2021)
Published in Cancers (21.04.2021)
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Journal Article
Plumbagin inhibits tumorigenesis and angiogenesis of ovarian cancer cells in vivo
Sinha, Sutapa, Pal, Krishnendu, Elkhanany, Ahmed, Dutta, Shamit, Cao, Ying, Mondal, Gourish, Iyer, Seethalakshmi, Somasundaram, Veena, Couch, Fergus J., Shridhar, Viji, Bhattacharya, Resham, Mukhopadhyay, Debabrata, Srinivas, Priya
Published in International journal of cancer (01.03.2013)
Published in International journal of cancer (01.03.2013)
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Journal Article
Role of Hedgehog Signaling in Ovarian Cancer
Bhattacharya, Resham, Kwon, Junhye, Ali, Bushra, Wang, Enfeng, Patra, Sujata, Shridhar, Viji, Mukherjee, Priyabrata
Published in Clinical cancer research (01.12.2008)
Published in Clinical cancer research (01.12.2008)
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Journal Article
PFKFB3 inhibition reprograms malignant pleural mesothelioma to nutrient stress-induced macropinocytosis and ER stress as independent binary adaptive responses
Sarkar Bhattacharya, Sayantani, Thirusangu, Prabhu, Jin, Ling, Roy, Debarshi, Jung, Deokbeom, Xiao, Yinan, Staub, Julie, Roy, Bhaskar, Molina, Julian R., Shridhar, Viji
Published in Cell death & disease (27.09.2019)
Published in Cell death & disease (27.09.2019)
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Journal Article
Combining copy number, methylation markers, and mutations as a panel for endometrial cancer detection via intravaginal tampon collection
Sangtani, Ajleeta, Wang, Chen, Weaver, Amy, Hoppman, Nicole L., Kerr, Sarah E., Abyzov, Alexej, Shridhar, Viji, Staub, Julie, Kocher, Jean-Pierre A., Voss, Jesse S., Podratz, Karl C., Wentzensen, Nicolas, Kisiel, John B., Sherman, Mark E., Bakkum-Gamez, Jamie N.
Published in Gynecologic oncology (01.02.2020)
Published in Gynecologic oncology (01.02.2020)
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Journal Article
Group III phospholipase A2 downregulation attenuated survival and metastasis in ovarian cancer and promotes chemo-sensitization
Ray, Upasana, Roy, Debarshi, Jin, Ling, Thirusangu, Prabhu, Staub, Julie, Xiao, Yinan, Kalogera, Eleftheria, Wahner Hendrickson, Andrea E, Cullen, Grace D, Goergen, Krista, Oberg, Ann L, Shridhar, Viji
Published in Journal of experimental & clinical cancer research (03.06.2021)
Published in Journal of experimental & clinical cancer research (03.06.2021)
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Journal Article
Serine Protease HtrA1 Associates with Microtubules and Inhibits Cell Migration
Chien, Jeremy, Ota, Takayo, Aletti, Giovanni, Shridhar, Ravi, Boccellino, Mariarosaria, Quagliuolo, Lucio, Baldi, Alfonso, Shridhar, Viji
Published in Molecular and Cellular Biology (01.08.2009)
Published in Molecular and Cellular Biology (01.08.2009)
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Journal Article
Quinacrine in endometrial cancer: Repurposing an old antimalarial drug
Kalogera, Eleftheria, MD, Roy, Debarshi, Ph.D, Khurana, Ashwani, Ph.D, Mondal, Susmita, Ph.D, Weaver, Amy L., MS, He, Xiaoping, MD. Ph.D, Dowdy, Sean C., MD, Shridhar, Viji, Ph.D
Published in Gynecologic oncology (01.07.2017)
Published in Gynecologic oncology (01.07.2017)
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Journal Article
Quinacrine Induces Nucleolar Stress in Treatment-Refractory Ovarian Cancer Cell Lines
Oien, Derek B., Ray, Upasana, Pathoulas, Christopher L., Jin, Ling, Thirusangu, Prabhu, Jung, Deokbeom, Kumka, Joseph E., Xiao, Yinan, Sarkar Bhattacharya, Sayantani, Montoya, Dennis, Chien, Jeremy, Shridhar, Viji
Published in Cancers (16.09.2021)
Published in Cancers (16.09.2021)
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Journal Article