High-Resolution Functional Proteomics by Active-Site Peptide Profiling
Okerberg, Eric S., Wu, Jiangyue, Zhang, Baohong, Samii, Babak, Blackford, Kelly, Winn, David T., Shreder, Kevin R., Burbaum, Jonathan J., Patricelli, Matthew P., Stubbe, JoAnne
Published in Proceedings of the National Academy of Sciences - PNAS (05.04.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (05.04.2005)
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Quinolone derivatives containing strained spirocycle as orally active glycogen synthase kinase 3β (GSK-3β) inhibitors for type 2 diabetics
Seto, Shigeki, Yumoto, Kazuhiko, Okada, Kyoko, Asahina, Yoshikazu, Iwane, Aya, Iwago, Maki, Terasawa, Reiko, Shreder, Kevin R., Murakami, Koji, Kohno, Yasushi
Published in Bioorganic & medicinal chemistry (01.02.2012)
Published in Bioorganic & medicinal chemistry (01.02.2012)
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Hit-to-lead optimization and kinase selectivity of imidazo[1,2-a]quinoxalin-4-amine derived JNK1 inhibitors
Li, Bei, Cociorva, Oana M., Nomanbhoy, Tyzoon, Weissig, Helge, Li, Qiang, Nakamura, Kai, Liyanage, Marek, Zhang, Melissa C., Shih, Ann Y., Aban, Arwin, Hu, Yi, Cajica, Julia, Pham, Lan, Kozarich, John W., Shreder, Kevin R.
Published in Bioorganic & medicinal chemistry letters (15.09.2013)
Published in Bioorganic & medicinal chemistry letters (15.09.2013)
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Amides of 4-hydroxy-8-methanesulfonylamino-quinoline-2-carboxylic acid as zinc-dependent inhibitors of Lp-PLA(2)
Hu, Yi, Lin, Emme C. K., Pham, Lan M., Cajica, Julia, Amantea, Christopher M., Okerberg, Eric, Brown, Heidi E., Fraser, Allister, Du, Lingling, Kohno, Yasushi, Ishiyama, Junichi, Kozarich, John W., Shreder, Kevin R.
Published in Bioorganic & medicinal chemistry letters (01.03.2013)
Published in Bioorganic & medicinal chemistry letters (01.03.2013)
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Synthesis and structure–activity relationship of 4-quinolone-3-carboxylic acid based inhibitors of glycogen synthase kinase-3β
Cociorva, Oana M., Li, Bei, Nomanbhoy, Tyzoon, Li, Qiang, Nakamura, Ayako, Nakamura, Kai, Nomura, Masahiro, Okada, Kyoko, Seto, Shigeki, Yumoto, Kazuhiro, Liyanage, Marek, Zhang, Melissa C., Aban, Arwin, Leen, Brandon, Szardenings, Anna Katrin, Rosenblum, Jonathan S., Kozarich, John W., Kohno, Yasushi, Shreder, Kevin R.
Published in Bioorganic & medicinal chemistry letters (01.10.2011)
Published in Bioorganic & medicinal chemistry letters (01.10.2011)
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Amides of xanthurenic acid as zinc-dependent inhibitors of Lp-PLA
Lin, Emme C.K, Hu, Yi, Amantea, Christopher M, Pham, Lan M, Cajica, Julia, Okerberg, Eric, Brown, Heidi E, Fraser, Allister, Du, Lingling, Kohno, Yasushi, Ishiyama, Junichi, Kozarich, John W, Shreder, Kevin R
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
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Synthesis and structure–activity relationship of (1-halo-2-naphthyl) carbamate-based inhibitors of KIAA1363 (NCEH1/AADACL1)
Shreder, Kevin R., Lin, Emme C.K., Wu, Jiangyue, Cajica, Julia, Amantea, Christopher M., Hu, Yi, Okerberg, Eric, Brown, Heidi E., Pham, Lan M., Chung, De Michael, Fraser, Allister S., McGee, Ethel, Rosenblum, Jonathan S., Kozarich, John W.
Published in Bioorganic & medicinal chemistry letters (01.09.2012)
Published in Bioorganic & medicinal chemistry letters (01.09.2012)
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6-Position optimization of tricyclic 4-quinolone-based inhibitors of glycogen synthase kinase-3β: Discovery of nitrile derivatives with picomolar potency
Li, Bei, Cociorva, Oana M., Nomanbhoy, Tyzoon, Li, Qiang, Nakamura, Kai, Nomura, Masahiro, Okada, Kyoko, Yumoto, Kazuhiro, Liyanage, Marek, Zhang, Melissa C., Aban, Arwin, Szardenings, Anna Katrin, Kozarich, John W., Kohno, Yasushi, Shreder, Kevin R.
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
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Synthesis of AX7593, a Quinazoline-Derived Photoaffinity Probe for EGFR
Shreder, Kevin R, Wong, Melissa S, Nomanbhoy, Tyzoon, Leventhal, Phillip S, Fuller, Stacy R
Published in Organic letters (14.10.2004)
Published in Organic letters (14.10.2004)
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Synthesis and optimization of 2-pyridin-3-yl-benzo[ d][1,3]oxazin-4-one based inhibitors of human neutrophil elastase
Shreder, Kevin R., Cajica, Julia, Du, Lingling, Fraser, Allister, Hu, Yi, Kohno, Yasushi, Lin, Emme C.K., Liu, Steve J., Okerberg, Eric, Pham, Lan, Wu, Jiangyue, Kozarich, John W.
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
Published in Bioorganic & medicinal chemistry letters (15.08.2009)
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Amides of xanthurenic acid as zinc-dependent inhibitors of Lp-PLA2
Lin, Emme C.K., Hu, Yi, Amantea, Christopher M., Pham, Lan M., Cajica, Julia, Okerberg, Eric, Brown, Heidi E., Fraser, Allister, Du, Lingling, Kohno, Yasushi, Ishiyama, Junichi, Kozarich, John W., Shreder, Kevin R.
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
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Design and Synthesis of AX7574: A Microcystin-Derived, Fluorescent Probe for Serine/Threonine Phosphatases
Shreder, Kevin R, Liu, Yongsheng, Nomanhboy, Tyzoon, Fuller, Stacy R, Wong, Melissa S, Gai, Wen Zhi, Wu, Jiangyue, Leventhal, Phillip S, Lill, Jennie R, Corral, Sergio
Published in Bioconjugate chemistry (01.07.2004)
Published in Bioconjugate chemistry (01.07.2004)
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Design and synthesis of AX4697, a bisindolylmaleimide exo-affinity probe that labels protein kinase C alpha and beta
Liu, Yongsheng, Wu, Jiangyue, Weissig, Helge, Betancort, Juan M., Gai, Wen Zhi, Leventhal, Phillip S., Patricelli, Matthew P., Samii, Babak, Szardenings, Anna K., Shreder, Kevin R., Kozarich, John W.
Published in Bioorganic & medicinal chemistry (15.11.2008)
Published in Bioorganic & medicinal chemistry (15.11.2008)
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Synthesis and structure–activity relationship of N-alkyl Gly-boro-Pro inhibitors of DPP4, FAP, and DPP7
Hu, Yi, Ma, Lifu, Wu, Min, Wong, Melissa S., Li, Bei, Corral, Sergio, Yu, Zhizhou, Nomanbhoy, Tyzoon, Alemayehu, Senaiet, Fuller, Stacy R., Rosenblum, Jonathan S., Rozenkrants, Natasha, Minimo, Lauro C., Ripka, William C., Szardenings, Anna K., Kozarich, John W., Shreder, Kevin R.
Published in Bioorganic & medicinal chemistry letters (01.10.2005)
Published in Bioorganic & medicinal chemistry letters (01.10.2005)
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Boro-norleucine as a P1 residue for the design of selective and potent DPP7 inhibitors
Shreder, Kevin R., Wong, Melissa S., Corral, Sergio, Yu, Zhizhou, Winn, David T., Wu, Min, Hu, Yi, Nomanbhoy, Tyzoon, Alemayehu, Senaiet, Fuller, Stacy R., Rosenblum, Jonathan S., Kozarich, John W.
Published in Bioorganic & medicinal chemistry letters (01.10.2005)
Published in Bioorganic & medicinal chemistry letters (01.10.2005)
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Amides of 4-hydroxy-8-methanesulfonylamino-quinoline-2-carboxylic acid as zinc-dependent inhibitors of Lp-PLA2
Hu, Yi, Lin, Emme C.K., Pham, Lan M., Cajica, Julia, Amantea, Christopher M., Okerberg, Eric, Brown, Heidi E., Fraser, Allister, Du, Lingling, Kohno, Yasushi, Ishiyama, Junichi, Kozarich, John W., Shreder, Kevin R.
Published in Bioorganic & medicinal chemistry letters (01.03.2013)
Published in Bioorganic & medicinal chemistry letters (01.03.2013)
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Journal Article
Amides of xanthurenic acid as zinc-dependent inhibitors of Lp-PL
Lin, Emme CK, Hu, Yi, Amantea, Christopher M, Pham, Lan M, Cajica, Julia, Okerberg, Eric, Brown, Heidi E, Fraser, Allister, Du, Lingling, Kohno, Yasushi, Ishiyama, Junichi, Kozarich, John W, Shreder, Kevin R, Burstein, Sumner, McQuain, Catherine, Salmonsen, Rebecca, Seicol, Benjamin
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
Published in Bioorganic & medicinal chemistry letters (15.01.2012)
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Synthesis and structure-activity relationship of 4-quinolone-3-carboxylic acid based inhibitors of glycogen synthase kinase-3[beta]
Cociorva, Oana M, Li, Bei, Nomanbhoy, Tyzoon, Li, Qiang, Nakamura, Ayako, Nakamura, Kai, Nomura, Masahiro, Okada, Kyoko, Seto, Shigeki, Yumoto, Kazuhiro, Liyanage, Marek, Zhang, Melissa C, Aban, Arwin, Leen, Brandon, Szardenings, Anna Katrin, Rosenblum, Jonathan S, Kozarich, John W, Kohno, Yasushi, Shreder, Kevin R
Published in Bioorganic & medicinal chemistry letters (01.10.2011)
Published in Bioorganic & medicinal chemistry letters (01.10.2011)
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