Stress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Diverse ER Proteostasis Environments
Shoulders, Matthew D., Ryno, Lisa M., Genereux, Joseph C., Moresco, James J., Tu, Patricia G., Wu, Chunlei, Yates, John R., Su, Andrew I., Kelly, Jeffery W., Wiseman, R. Luke
Published in Cell reports (Cambridge) (25.04.2013)
Published in Cell reports (Cambridge) (25.04.2013)
Get full text
Journal Article
An Adaptable Platform for Directed Evolution in Human Cells
Berman, Chet M, Papa, Louis J, Hendel, Samuel J, Moore, Christopher L, Suen, Patreece H, Weickhardt, Alexander F, Doan, Ngoc-Duc, Kumar, Caiden M, Uil, Taco G, Butty, Vincent L, Hoeben, Robert C, Shoulders, Matthew D
Published in Journal of the American Chemical Society (26.12.2018)
Published in Journal of the American Chemical Society (26.12.2018)
Get full text
Journal Article
The endoplasmic reticulum proteostasis network profoundly shapes the protein sequence space accessible to HIV envelope
Yoon, Jimin, Nekongo, Emmanuel E, Patrick, Jessica E, Hui, Tiffani, Phillips, Angela M, Ponomarenko, Anna I, Hendel, Samuel J, Sebastian, Rebecca M, Zhang, Yu Meng, Butty, Vincent L, Ogbunugafor, C Brandon, Lin, Yu-Shan, Shoulders, Matthew D
Published in PLoS biology (18.02.2022)
Published in PLoS biology (18.02.2022)
Get full text
Journal Article
A cysteine-based molecular code informs collagen C-propeptide assembly
DiChiara, Andrew S., Li, Rasia C., Suen, Patreece H., Hosseini, Azade S., Taylor, Rebecca J., Weickhardt, Alexander F., Malhotra, Diya, McCaslin, Darrell R., Shoulders, Matthew D.
Published in Nature communications (11.10.2018)
Published in Nature communications (11.10.2018)
Get full text
Journal Article
Characterization of an A‑Site Selective Protein Disulfide Isomerase A1 Inhibitor
Cole, Kyle S, Grandjean, Julia M. D, Chen, Kenny, Witt, Collin H, O’Day, Johanna, Shoulders, Matthew D, Wiseman, R. Luke, Weerapana, Eranthie
Published in Biochemistry (Easton) (03.04.2018)
Published in Biochemistry (Easton) (03.04.2018)
Get full text
Journal Article
A Method for Selective Depletion of Zn(II) Ions from Complex Biological Media and Evaluation of Cellular Consequences of Zn(II) Deficiency
Richardson, Christopher E. R, Cunden, Lisa S, Butty, Vincent L, Nolan, Elizabeth M, Lippard, Stephen J, Shoulders, Matthew D
Published in Journal of the American Chemical Society (21.02.2018)
Published in Journal of the American Chemical Society (21.02.2018)
Get full text
Journal Article
Destabilized adaptive influenza variants critical for innate immune system escape are potentiated by host chaperones
Phillips, Angela M, Ponomarenko, Anna I, Chen, Kenny, Ashenberg, Orr, Miao, Jiayuan, McHugh, Sean M, Butty, Vincent L, Whittaker, Charles A, Moore, Christopher L, Bloom, Jesse D, Lin, Yu-Shan, Shoulders, Matthew D
Published in PLoS biology (17.09.2018)
Published in PLoS biology (17.09.2018)
Get full text
Journal Article
Mapping and Exploring the Collagen‑I Proteostasis Network
DiChiara, Andrew S, Taylor, Rebecca J, Wong, Madeline Y, Doan, Ngoc-Duc, Rosario, Amanda M. Del, Shoulders, Matthew D
Published in ACS chemical biology (20.05.2016)
Published in ACS chemical biology (20.05.2016)
Get full text
Journal Article
Reciprocity of Steric and Stereoelectronic Effects in the Collagen Triple Helix
Shoulders, Matthew D, Hodges, Jonathan A, Raines, Ronald T
Published in Journal of the American Chemical Society (28.06.2006)
Published in Journal of the American Chemical Society (28.06.2006)
Get full text
Journal Article
Using CRISPR/Cas9 to generate a heterozygous COL2A1 p.R719C iPSC line (MCRIi019-A-6) model of human precocious osteoarthritis
Yammine, Kathryn M., Mirda Abularach, Sophia, Sampurno, Lisa, Bateman, John F., Lamandé, Shireen R., Shoulders, Matthew D.
Published in Stem cell research (01.03.2023)
Published in Stem cell research (01.03.2023)
Get full text
Journal Article
A High-Throughput Assay for Collagen Secretion Suggests an Unanticipated Role for Hsp90 in Collagen Production
Wong, Madeline Y, Doan, Ngoc Duc, DiChiara, Andrew S, Papa, Louis J, Cheah, Jaime H, Soule, Christian K, Watson, Nicki, Hulleman, John D, Shoulders, Matthew D
Published in Biochemistry (Easton) (15.05.2018)
Published in Biochemistry (Easton) (15.05.2018)
Get full text
Journal Article
Enhanced ER proteostasis and temperature differentially impact the mutational tolerance of influenza hemagglutinin
Phillips, Angela M, Doud, Michael B, Gonzalez, Luna O, Butty, Vincent L, Lin, Yu-Shan, Bloom, Jesse D, Shoulders, Matthew D
Published in eLife (06.09.2018)
Published in eLife (06.09.2018)
Get full text
Journal Article
The Aberrance of the 4S Diastereomer of 4-Hydroxyproline
Shoulders, Matthew D, Kotch, Frank W, Choudhary, Amit, Guzei, Ilia A, Raines, Ronald T
Published in Journal of the American Chemical Society (11.08.2010)
Published in Journal of the American Chemical Society (11.08.2010)
Get full text
Journal Article
Characterizing the Altered Cellular Proteome Induced by the Stress-Independent Activation of Heat Shock Factor 1
Ryno, Lisa M, Genereux, Joseph C, Naito, Tadasuke, Morimoto, Richard I, Powers, Evan T, Shoulders, Matthew D, Wiseman, R. Luke
Published in ACS chemical biology (20.06.2014)
Published in ACS chemical biology (20.06.2014)
Get full text
Journal Article
CRISPR/Cas9 editing to generate a heterozygous COL2A1 p.G1170S human chondrodysplasia iPSC line, MCRIi019-A-2, in a control iPSC line, MCRIi019-A
Kung, Louise H.W., Sampurno, Lisa, Yammine, Kathryn M., Graham, Alison, McDonald, Penny, Bateman, John F., Shoulders, Matthew D., Lamandé, Shireen R.
Published in Stem cell research (01.10.2020)
Published in Stem cell research (01.10.2020)
Get full text
Journal Article
Host proteostasis modulates influenza evolution
Phillips, Angela M, Gonzalez, Luna O, Nekongo, Emmanuel E, Ponomarenko, Anna I, McHugh, Sean M, Butty, Vincent L, Levine, Stuart S, Lin, Yu-Shan, Mirny, Leonid A, Shoulders, Matthew D
Published in eLife (26.09.2017)
Published in eLife (26.09.2017)
Get full text
Journal Article
Origin of the stability conferred upon collagen by fluorination
Shoulders, Matthew D., Kamer, Kimberli J., Raines, Ronald T.
Published in Bioorganic & medicinal chemistry letters (15.07.2009)
Published in Bioorganic & medicinal chemistry letters (15.07.2009)
Get full text
Journal Article