Small Molecule Inhibitors of Cyclophilin D To Protect Mitochondrial Function as a Potential Treatment for Acute Pancreatitis
Shore, Emma R, Awais, Muhammad, Kershaw, Neil M, Gibson, Robert R, Pandalaneni, Sravan, Latawiec, Diane, Wen, Li, Javed, Muhammad A, Criddle, David N, Berry, Neil, O’Neill, Paul M, Lian, Lu-Yun, Sutton, Robert
Published in Journal of medicinal chemistry (24.03.2016)
Published in Journal of medicinal chemistry (24.03.2016)
Get full text
Journal Article
Optimisation of the synthesis of second generation 1,2,4,5 tetraoxane antimalarials
O' Neill, Paul M., Sabbani, Sunil, Nixon, Gemma L., Schnaderbeck, Matthew, Roberts, Natalie L., Shore, Emma R., Riley, Christopher, Murphy, Ben, McGillan, Paul, Ward, Stephen A., Davies, Jill, Amewu, Richard K.
Published in Tetrahedron (06.10.2016)
Published in Tetrahedron (06.10.2016)
Get full text
Journal Article
Synthesis and profiling of benzylmorpholine 1,2,4,5-tetraoxane analogue N205: Towards tetraoxane scaffolds with potential for single dose cure of malaria
O' Neill, Paul M., Stocks, Paul A., Sabbani, Sunil, Roberts, Natalie L., Amewu, Richard K., Shore, Emma R., Aljayyoussi, Ghaith, Angulo-Barturén, Iñigo, Belén, María, Jiménez-Díaz, Bazaga, Santiago Ferrer, Martínez, María Santos, Campo, Brice, Sharma, Raman, Charman, Susan A., Ryan, Eileen, Chen, Gong, Shackleford, David M., Davies, Jill, Nixon, Gemma L., Biagini, Giancarlo A., Ward, Stephen A.
Published in Bioorganic & medicinal chemistry (15.07.2018)
Published in Bioorganic & medicinal chemistry (15.07.2018)
Get full text
Journal Article
A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance
O’Neill, Paul M., Amewu, Richard K., Charman, Susan A., Sabbani, Sunil, Gnädig, Nina F., Straimer, Judith, Fidock, David A., Shore, Emma R., Roberts, Natalie L., Wong, Michael H.-L., Hong, W. David, Pidathala, Chandrakala, Riley, Chris, Murphy, Ben, Aljayyoussi, Ghaith, Gamo, Francisco Javier, Sanz, Laura, Rodrigues, Janneth, Cortes, Carolina Gonzalez, Herreros, Esperanza, Angulo-Barturén, Iñigo, Jiménez-Díaz, María Belén, Bazaga, Santiago Ferrer, Martínez-Martínez, María Santos, Campo, Brice, Sharma, Raman, Ryan, Eileen, Shackleford, David M., Campbell, Simon, Smith, Dennis A., Wirjanata, Grennady, Noviyanti, Rintis, Price, Ric N., Marfurt, Jutta, Palmer, Michael J., Copple, Ian M., Mercer, Amy E., Ruecker, Andrea, Delves, Michael J., Sinden, Robert E., Siegl, Peter, Davies, Jill, Rochford, Rosemary, Kocken, Clemens H. M., Zeeman, Anne-Marie, Nixon, Gemma L., Biagini, Giancarlo A., Ward, Stephen A.
Published in Nature communications (24.05.2017)
Published in Nature communications (24.05.2017)
Get full text
Journal Article