Tonabersat Inhibits Connexin43 Hemichannel Opening and Inflammasome Activation in an In Vitro Retinal Epithelial Cell Model of Diabetic Retinopathy
Lyon, Heather, Shome, Avik, Rupenthal, Ilva D, Green, Colin R, Mugisho, Odunayo O
Published in International journal of molecular sciences (30.12.2020)
Published in International journal of molecular sciences (30.12.2020)
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Next-Generation Hypoxic Cell Radiosensitizers: Nitroimidazole Alkylsulfonamides
Bonnet, Muriel, Hong, Cho Rong, Wong, Way Wua, Liew, Lydia P, Shome, Avik, Wang, Jingli, Gu, Yongchuan, Stevenson, Ralph J, Qi, Wen, Anderson, Robert F, Pruijn, Frederik B, Wilson, William R, Jamieson, Stephen M. F, Hicks, Kevin O, Hay, Michael P
Published in Journal of medicinal chemistry (08.02.2018)
Published in Journal of medicinal chemistry (08.02.2018)
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Orally Delivered Connexin43 Hemichannel Blocker, Tonabersat, Inhibits Vascular Breakdown and Inflammasome Activation in a Mouse Model of Diabetic Retinopathy
Mugisho, Odunayo O, Aryal, Jyoti, Shorne, Avik, Lyon, Heather, Acosta, Monica L, Green, Colin R, Rupenthal, Ilva D
Published in International journal of molecular sciences (15.02.2023)
Published in International journal of molecular sciences (15.02.2023)
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Journal Article
Design, Synthesis and Anticancer Evaluation of Nitroimidazole Radiosensitisers
Liew, Lydia P, Shome, Avik, Wong, Way W, Hong, Cho R, Hicks, Kevin O, Jamieson, Stephen M F, Hay, Michael P
Published in Molecules (Basel, Switzerland) (31.05.2023)
Published in Molecules (Basel, Switzerland) (31.05.2023)
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Comprehensive Grading System for Experimental Autoimmune Uveitis in Mice
Shome, Avik, Mugisho, Odunayo O, Niederer, Rachael L, Rupenthal, Ilva D
Published in Biomedicines (01.07.2023)
Published in Biomedicines (01.07.2023)
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Journal Article
Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance
Mountjoy, Kathleen G., Caron, Alexandre, Hubbard, Kristina, Shome, Avik, Grey, Angus C., Sun, Bo, Bould, Sarah, Middleditch, Martin, Pontré, Beau, McGregor, Ailsa, Harris, Paul W.R., Kowalczyk, Renata, Brimble, Margaret A., Botha, Rikus, Tan, Karen M.L., Piper, Sarah J., Buchanan, Christina, Lee, Syann, Coll, Anthony P., Elmquist, Joel K.
Published in Molecular metabolism (Germany) (01.03.2018)
Published in Molecular metabolism (Germany) (01.03.2018)
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Blocking the inflammasome: A novel approach to treat uveitis
Shome, Avik, Mugisho, Odunayo O., Niederer, Rachael L., Rupenthal, Ilva D.
Published in Drug discovery today (01.12.2021)
Published in Drug discovery today (01.12.2021)
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Identification of 6-Anilino Imidazo4,5-cpyridin-2-ones as Selective DNA-Dependent Protein Kinase Inhibitors and Their Application as Radiosensitizers
Hong, Cho R, Liew, Lydia P, Wong, Way W, Dickson, Benjamin D, Cheng, Gary, Shome, Avik, Airey, Rebecca, Jaiswal, Jagdish, Lipert, Barbara, Jamieson, Stephen M F, Wilson, William R, Hay, Michael P
Published in Journal of medicinal chemistry (25.07.2024)
Published in Journal of medicinal chemistry (25.07.2024)
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Journal Article
Connexin43 hemichannel block inhibits NLRP3 inflammasome activation in a human retinal explant model of diabetic retinopathy
Louie, Henry H., Shome, Avik, Kuo, Charisse YJ, Rupenthal, Ilva D., Green, Colin R., Mugisho, Odunayo O.
Published in Experimental eye research (01.01.2021)
Published in Experimental eye research (01.01.2021)
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Journal Article
Chronic High-Fat Diet Exacerbates Sexually Dimorphic Pomctm1/tm1 Mouse Obesity
Hubbard, Kristina, Shome, Avik, Sun, Bo, Pontré, Beau, McGregor, Ailsa, Mountjoy, Kathleen G
Published in Endocrinology (Philadelphia) (01.05.2019)
Published in Endocrinology (Philadelphia) (01.05.2019)
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Journal Article
Chronic High-Fat Diet Exacerbates Sexually Dimorphic [P.sup.omctm1/tm1] Mouse Obesity
Hubbard, Kristina, Shome, Avik, Sun, Bo, Pontre, Beau, McGregor, Ailsa, Mountjoy, Kathleen G
Published in Endocrinology (Philadelphia) (01.05.2019)
Published in Endocrinology (Philadelphia) (01.05.2019)
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Journal Article
Identification of 6‑Anilino Imidazo[4,5‑c]pyridin-2-ones as Selective DNA-Dependent Protein Kinase Inhibitors and Their Application as Radiosensitizers
Hong, Cho R., Liew, Lydia P., Wong, Way W., Dickson, Benjamin D., Cheng, Gary, Shome, Avik, Airey, Rebecca, Jaiswal, Jagdish, Lipert, Barbara, Jamieson, Stephen M. F., Wilson, William R., Hay, Michael P.
Published in Journal of medicinal chemistry (25.07.2024)
Published in Journal of medicinal chemistry (25.07.2024)
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Journal Article
Abstract 169: Preclinical efficacy and sensitivity determinants of evofosfamide in molecularly defined models of head and neck squamous cell carcinoma
Hunter, Francis W., Shome, Avik, Li, Dan, Wong, Way W., Tsai, Peter, Poonawala, Nooriyah, Kakadiya, Purvi M., Ketelä, Troy M., Kondratyev, Maria K., Lynch, Courtney R., Lee, Tet-Woo, Tran, Khanh B., Devaux, Jules B., Zussman, Rachel, Hong, Cho R., Kee, Dennis, Macann, Andrew M., Hickey, Anthony J., Bohlander, Stefan K., Print, Cristin G., Wilson, William R., Wouters, Bradly G., Jamieson, Stephen M.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma
Jamieson, Stephen Mf, Tsai, Peter, Kondratyev, Maria K, Budhani, Pratha, Liu, Arthur, Senzer, Neil N, Chiorean, E Gabriela, Jalal, Shadia I, Nemunaitis, John J, Kee, Dennis, Shome, Avik, Wong, Way W, Li, Dan, Poonawala-Lohani, Nooriyah, Kakadia, Purvi M, Knowlton, Nicholas S, Lynch, Courtney Rh, Hong, Cho R, Lee, Tet Woo, Grénman, Reidar A, Caporiccio, Laura, McKee, Trevor D, Zaidi, Mark, Butt, Sehrish, Macann, Andrew Mj, McIvor, Nicholas P, Chaplin, John M, Hicks, Kevin O, Bohlander, Stefan K, Wouters, Bradly G, Hart, Charles P, Print, Cristin G, Wilson, William R, Curran, Michael A, Hunter, Francis W
Published in JCI insight (23.08.2018)
Published in JCI insight (23.08.2018)
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Journal Article
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma
Jamieson, Stephen Mf, Tsai, Peter, Kondratyev, Maria K, Budhani, Pratha, Liu, Arthur, Senzer, Neil N, Chiorean, E Gabriela, Jalal, Shadia I, Nemunaitis, John J, Kee, Dennis, Shome, Avik, Wong, Way W, Li, Dan, Poonawala-Lohani, Nooriyah, Kakadia, Purvi M, Knowlton, Nicholas S, Lynch, Courtney Rh, Hong, Cho R, Lee, Tet Woo, Grénman, Reidar A, Caporiccio, Laura, McKee, Trevor D, Zaidi, Mark, Butt, Sehrish, Macann, Andrew Mj, McIvor, Nicholas P, Chaplin, John M, Hicks, Kevin O, Bohlander, Stefan K, Wouters, Bradly G, Hart, Charles P, Print, Cristin G, Wilson, William R, Curran, Michael A, Hunter, Francis W
Published in JCI insight (22.02.2023)
Published in JCI insight (22.02.2023)
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Journal Article
Real-time assessment of encapsulated neonatal porcine islets prior to clinical xenotransplantation
Kitzmann, Jennifer P., Law, Lee, Shome, Avik, Muzina, Marija, Elliott, Robert B., Mueller, Kate R., Schuurman, Henk-Jan, Papas, Klearchos K.
Published in Xenotransplantation (Københaven) (01.11.2012)
Published in Xenotransplantation (Københaven) (01.11.2012)
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