Osteogenic Effects of KY-054, a Novel Coumarin Derivative on Femur Cortical Bone in Ovariectomized Female Rats
Yamamoto, Megumi, Ito, Yuma, Fukui, Masaki, Otake, Kazuya, Shoji, Yoshimichi, Kitao, Tatsuya, Shirahase, Hiroaki, Hinoi, Eiichi
Published in Biological & pharmaceutical bulletin (01.10.2023)
Published in Biological & pharmaceutical bulletin (01.10.2023)
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Journal Article
Osteoblastgenic and Osteogenic Effects of KY-273 with CDK8/19 Inhibitory Activity in Bone Marrow Mesenchymal Stem Cells and Female Rats
Yamamoto, Megumi, Shibata, Yui, Ito, Yuma, Fukui, Masaki, Kioka, Hikaru, Shoji, Yoshimichi, Kitao, Tatsuya, Shirahase, Hiroaki, Hinoi, Eiichi
Published in Biological & pharmaceutical bulletin (2024)
Published in Biological & pharmaceutical bulletin (2024)
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Journal Article
Discovery of Novel Chromenopyridine Derivatives as Readthrough-Inducing Drugs
Kawai, Shota, Takashima, Shunsuke, Ando, Masafumi, Shintaku, Sayaka, Takeda, Shigemitsu, Otake, Kazuya, Ito, Yuma, Fukui, Masaki, Yamamoto, Megumi, Shoji, Yoshimichi, Shirahase, Hiroaki, Kitao, Tatsuya
Published in Chemical & pharmaceutical bulletin (01.12.2023)
Published in Chemical & pharmaceutical bulletin (01.12.2023)
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Journal Article
Synthesis and Evaluation of Novel Triaryl Derivatives with Readthrough-Inducing Activity
Kawai, Shota, Takashima, Shunsuke, Ando, Masafumi, Shintaku, Sayaka, Takeda, Shigemitsu, Otake, Kazuya, Ito, Yuma, Fukui, Masaki, Yamamoto, Megumi, Shoji, Yoshimichi, Shirahase, Hiroaki, Kitao, Tatsuya
Published in Chemical & pharmaceutical bulletin (01.09.2023)
Published in Chemical & pharmaceutical bulletin (01.09.2023)
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Journal Article
Therapeutic effects of the allosteric protein tyrosine phosphatase 1B inhibitor KY-226 on experimental diabetes and obesity via enhancements in insulin and leptin signaling in mice
Ito, Yuma, Fukui, Masaki, Kanda, Mamoru, Morishita, Ko, Shoji, Yoshimichi, Kitao, Tatsuya, Hinoi, Eiichi, Shirahase, Hiroaki
Published in Journal of pharmacological sciences (01.05.2018)
Published in Journal of pharmacological sciences (01.05.2018)
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Journal Article
Novel Non-carboxylate Benzoylsulfonamide-Based Protein Tyrosine Phosphatase 1B Inhibitors with Non-competitive Actions
Morishita, Ko, Shoji, Yoshimichi, Tanaka, Shunkichi, Fukui, Masaki, Ito, Yuma, Kitao, Tatsuya, Ozawa, Shin-ichiro, Hirono, Shuichi, Shirahase, Hiroaki
Published in Chemical & pharmaceutical bulletin (01.12.2017)
Published in Chemical & pharmaceutical bulletin (01.12.2017)
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Journal Article
2-Acyl-3-carboxyl-tetrahydroisoquinoline Derivatives: Mixed-Type PTP1B Inhibitors without PPARγ Activation
Morishita, Ko, Shoji, Yoshimichi, Fukui, Masaki, Ito, Yuma, Kitao, Tatsuya, Ozawa, Shin-ichiro, Hirono, Shuichi, Shirahase, Hiroaki
Published in Chemical & pharmaceutical bulletin (01.12.2018)
Published in Chemical & pharmaceutical bulletin (01.12.2018)
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Journal Article
Novel Acyl-CoA: Cholesterol Acyltransferase Inhibitor: Indoline-Based Sulfamide Derivatives with Low Lipophilicity and Protein Binding Ratio
Takahashi, Kenji, Ohta, Masaru, Shoji, Yoshimichi, Kasai, Masayasu, Kunishiro, Kazuyoshi, Miike, Tomohiro, Kanda, Mamoru, Shirahase, Hiroaki
Published in Chemical & pharmaceutical bulletin (01.08.2010)
Published in Chemical & pharmaceutical bulletin (01.08.2010)
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Journal Article
Novel Tetrahydroisoquinoline Derivatives with Inhibitory Activities against Acyl-CoA: Cholesterol Acyltransferase and Lipid Peroxidation
Ohta, Masaru, Takahashi, Kenji, Kasai, Masayasu, Shoji, Yoshimichi, Kunishiro, Kazuyoshi, Miike, Tomohiro, Kanda, Mamoru, Mukai, Chisato, Shirahase, Hiroaki
Published in Chemical & pharmaceutical bulletin (01.08.2010)
Published in Chemical & pharmaceutical bulletin (01.08.2010)
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Journal Article
Novel Non-carboxylate Benzoylsulfonamide-Based Protein Tyrosine Phosphatase 1B Inhibitors with Non-competitive Actions
Ko Morishitaa, Yoshimichi Shojia, Shunkichi Tanakaa, Masaki Fukuia, Yuma Itoa, Tatsuya Kitaoa, Shin-ichiro Ozawab, Shuichi Hironob, Hiroaki Shirahasea
Published in Chemical and Pharmaceutical Bulletin (01.12.2017)
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Published in Chemical and Pharmaceutical Bulletin (01.12.2017)
Journal Article
2-Acyl-3-carboxyl-tetrahydroisoquinoline Derivatives : Mixed-Type PTP1B Inhibitors without PPARγ Activation
Ko Morishitaa, Yoshimichi Shojia, Masaki Fukuia, Yuma Itoa, Tatsuya Kitaoa, Shin-ichiro Ozawab, Shuichi Hironob, Hiroaki Shirahasea
Published in Chemical and Pharmaceutical Bulletin (01.12.2018)
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Published in Chemical and Pharmaceutical Bulletin (01.12.2018)
Journal Article
Novel Acyl-CoA: Cholesterol Acyltransferase Inhibitor: Indoline-Based Sulfamide Derivatives with Low Lipophilicity and Protein Binding Ratio
Kenji TAKAHASHI, Masaru OHTA, Yoshimichi SHOJI, Masayasu KASAI, Kazuyoshi KUNISHIRO, Tomohiro MIIKE, Mamoru KANDA, Hiroaki SHIRAHASE
Published in Chemical & Pharmaceutical Bulletin (2010)
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Published in Chemical & Pharmaceutical Bulletin (2010)
Journal Article
Novel Tetrahydroisoquinoline Derivatives with Inhibitory Activities against Acyl-CoA: Cholesterol Acyltransferase and Lipid Peroxidation
Masaru OHTAa, b, Kenji TAKAHASHIa, Masayasu KASAIa, Yoshimichi SHOJIa, Kazuyoshi KUNISHIROa, Tomohiro MIIKEa, Mamoru KANDAa, Chisato MUKAIb, Hiroaki SHIRAHASEa
Published in Chemical & Pharmaceutical Bulletin (2010)
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Published in Chemical & Pharmaceutical Bulletin (2010)
Journal Article