PRMT5 activates AKT via methylation to promote tumor metastasis
Huang, Lei, Zhang, Xiao-Ou, Rozen, Esteban J, Sun, Xiaomei, Sallis, Benjamin, Verdejo-Torres, Odette, Wigglesworth, Kim, Moon, Daniel, Huang, Tingting, Cavaretta, John P, Wang, Gang, Zhang, Lei, Shohet, Jason M, Lee, Mary M, Wu, Qiong
Published in Nature communications (08.07.2022)
Published in Nature communications (08.07.2022)
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WIP1 phosphatase as a potential therapeutic target in neuroblastoma
Richter, Mark, Dayaram, Tajhal, Gilmartin, Aidan G, Ganji, Gopinath, Pemmasani, Sandhya Kiran, Van Der Key, Harjeet, Shohet, Jason M, Donehower, Lawrence A, Kumar, Rakesh
Published in PloS one (06.02.2015)
Published in PloS one (06.02.2015)
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CD114: A New Member of the Neural Crest‐Derived Cancer Stem Cell Marker Family
Zage, Peter E., Whittle, Sarah B., Shohet, Jason M.
Published in Journal of cellular biochemistry (01.02.2017)
Published in Journal of cellular biochemistry (01.02.2017)
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The role of histone demethylase KDM4B in Myc signaling in neuroblastoma
Yang, Jun, AlTahan, Alaa M, Hu, Dongli, Wang, Yingdi, Cheng, Pei-Hsin, Morton, Christopher L, Qu, Chunxu, Nathwani, Amit C, Shohet, Jason M, Fotsis, Theodore, Koster, Jan, Versteeg, Rogier, Okada, Hitoshi, Harris, Adrian L, Davidoff, Andrew M
Published in JNCI : Journal of the National Cancer Institute (01.06.2015)
Published in JNCI : Journal of the National Cancer Institute (01.06.2015)
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MYCN acts as a direct co-regulator of p53 in MYCN amplified neuroblastoma
Agarwal, Saurabh, Milazzo, Giorgio, Rajapakshe, Kimal, Bernardi, Ronald, Chen, Zaowen, Barbieri, Eveline, Koster, Jan, Perini, Giovanni, Coarfa, Cristian, Shohet, Jason M
Published in Oncotarget (17.04.2018)
Published in Oncotarget (17.04.2018)
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MDM2-p53 interaction in paediatric solid tumours: preclinical rationale, biomarkers and resistance
Barone, Giuseppe, Tweddle, Deborah A, Shohet, Jason M, Chesler, Louis, Moreno, Lucas, Pearson, Andrew D J, Van Maerken, Tom
Published in Current drug targets (01.01.2014)
Published in Current drug targets (01.01.2014)
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Journal Article
A p53 drug response signature identifies prognostic genes in high-risk neuroblastoma
Barbieri, Eveline, De Preter, Katleen, Capasso, Mario, Johansson, Peter, Man, Tsz-Kwong, Chen, Zaowen, Stowers, Paris, Tonini, Gian Paolo, Speleman, Frank, Shohet, Jason M
Published in PloS one (19.11.2013)
Published in PloS one (19.11.2013)
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G-CSF Receptor Positive Neuroblastoma Subpopulations Are Enriched in Chemotherapy-Resistant or Relapsed Tumors and Are Highly Tumorigenic
HSU, Danielle M, AGARWAL, Saurabh, METELITSA, Leonid S, GUNARATNE, Preethi, KIM, Eugene S, SHOHET, Jason M, BENHAM, Ashley, COARFA, Cristian, TRAHAN, Denae N, CHEN, Zaowen, STOWERS, Paris N, COURTNEY, Amy N, LAKOMA, Anna, BARBIERI, Eveline
Published in Cancer research (Chicago, Ill.) (01.07.2013)
Published in Cancer research (Chicago, Ill.) (01.07.2013)
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MDM2 inhibition sensitizes neuroblastoma to chemotherapy-induced apoptotic cell death
Barbieri, Eveline, Mehta, Parth, Chen, Zaowen, Zhang, Linna, Slack, Andrew, Berg, Stacey, Shohet, Jason M
Published in Molecular cancer therapeutics (01.09.2006)
Published in Molecular cancer therapeutics (01.09.2006)
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Journal Article
The p53 Regulatory Gene MDM2 Is a Direct Transcriptional Target of MYCN in Neuroblastoma
Slack, Andrew, Chen, Zaowen, Tonelli, Roberto, Pule, Martin, Hunt, Lisa, Pession, Andrea, Shohet, Jason M., Eisenman, Robert N.
Published in Proceedings of the National Academy of Sciences - PNAS (18.01.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (18.01.2005)
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Journal Article
Aurora B kinase is a potent and selective target in MYCN-driven neuroblastoma
Bogen, Dominik, Wei, Jun S, Azorsa, David O, Ormanoglu, Pinar, Buehler, Eugen, Guha, Rajarshi, Keller, Jonathan M, Mathews Griner, Lesley A, Ferrer, Marc, Song, Young K, Liao, Hongling, Mendoza, Arnulfo, Gryder, Berkley E, Sindri, Sivasish, He, Jianbin, Wen, Xinyu, Zhang, Shile, Shern, John F, Yohe, Marielle E, Taschner-Mandl, Sabine, Shohet, Jason M, Thomas, Craig J, Martin, Scott E, Ambros, Peter F, Khan, Javed
Published in Oncotarget (03.11.2015)
Published in Oncotarget (03.11.2015)
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Neuroblastoma pathogenesis: deregulation of embryonic neural crest development
Tomolonis, Julie A., Agarwal, Saurabh, Shohet, Jason M.
Published in Cell and tissue research (01.05.2018)
Published in Cell and tissue research (01.05.2018)
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Journal Article
Effect of MDM2 and vascular endothelial growth factor inhibition on tumor angiogenesis and metastasis in neuroblastoma
Patterson, Danielle M., Gao, Dongbing, Trahan, Denae N., Johnson, Brett A., Ludwig, Andrew, Barbieri, Eveline, Chen, Zaowen, Diaz-Miron, Jose, Vassilev, Lyubomir, Shohet, Jason M., Kim, Eugene S.
Published in Angiogenesis (London) (01.09.2011)
Published in Angiogenesis (London) (01.09.2011)
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Journal Article
Mdm2 Deficiency Suppresses MYCN-Driven Neuroblastoma Tumorigenesis In Vivo
Chen, Zaowen, Lin, Yunfu, Barbieri, Eveline, Burlingame, Sue, Hicks, John, Ludwig, Andrew, Shohet, Jason M.
Published in Neoplasia (New York, N.Y.) (01.08.2009)
Published in Neoplasia (New York, N.Y.) (01.08.2009)
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A gold nanoparticle platform for the delivery of functional microRNAs into cancer cells
Ghosh, Rajib, Singh, Lalithya C, Shohet, Jason M, Gunaratne, Preethi H
Published in Biomaterials (01.01.2013)
Published in Biomaterials (01.01.2013)
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Journal Article
Blockade of Discoidin Domain Receptor Signaling with Sitravatinib Reveals DDR2 as a Mediator of Neuroblastoma Pathogenesis and Metastasis
Rozen, Esteban J, Frantz, William, Wigglesworth, Kim, Vessella, Theadora, Zhou, Hong Susan, Shohet, Jason M
Published in Molecular cancer therapeutics (01.08.2024)
Published in Molecular cancer therapeutics (01.08.2024)
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Journal Article
G-CSF Promotes Neuroblastoma Tumorigenicity and Metastasis via STAT3-Dependent Cancer Stem Cell Activation
Agarwal, Saurabh, Lakoma, Anna, Chen, Zaowen, Hicks, John, Metelitsa, Leonid S, Kim, Eugene S, Shohet, Jason M
Published in Cancer research (Chicago, Ill.) (15.06.2015)
Published in Cancer research (Chicago, Ill.) (15.06.2015)
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