Using What We Already Have: Uncovering New Drug Repurposing Strategies in Existing Omics Data
Pulley, Jill M, Rhoads, Jillian P, Jerome, Rebecca N, Challa, Anup P, Erreger, Kevin B, Joly, Meghan M, Lavieri, Robert R, Perry, Kelly E, Zaleski, Nicole M, Shirey-Rice, Jana K, Aronoff, David M
Published in Annual review of pharmacology and toxicology (06.01.2020)
Published in Annual review of pharmacology and toxicology (06.01.2020)
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Journal Article
Human and Machine Intelligence Together Drive Drug Repurposing in Rare Diseases
Challa, Anup P, Zaleski, Nicole M, Jerome, Rebecca N, Lavieri, Robert R, Shirey-Rice, Jana K, Barnado, April, Lindsell, Christopher J, Aronoff, David M, Crofford, Leslie J, Harris, Raymond C, Alp Ikizler, T, Mayer, Ingrid A, Holroyd, Kenneth J, Pulley, Jill M
Published in Frontiers in genetics (28.07.2021)
Published in Frontiers in genetics (28.07.2021)
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Journal Article
Norepinephrine transporter variant A457P knock-in mice display key features of human postural orthostatic tachycardia syndrome
Shirey-Rice, Jana K, Klar, Rebecca, Fentress, Hugh M, Redmon, Sarah N, Sabb, Tiffany R, Krueger, Jessica J, Wallace, Nathan M, Appalsamy, Martin, Finney, Charlene, Lonce, Suzanna, Diedrich, André, Hahn, Maureen K
Published in Disease models & mechanisms (01.07.2013)
Published in Disease models & mechanisms (01.07.2013)
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Journal Article
PheWAS-ME: a web-app for interactive exploration of multimorbidity patterns in PheWAS
Strayer, Nick, Shirey-Rice, Jana K, Shyr, Yu, Denny, Joshua C, Pulley, Jill M, Xu, Yaomin
Published in Bioinformatics (19.07.2021)
Published in Bioinformatics (19.07.2021)
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Journal Article
Mining 100 million notes to find homelessness and adverse childhood experiences: 2 case studies of rare and severe social determinants of health in electronic health records
Bejan, Cosmin A, Angiolillo, John, Conway, Douglas, Nash, Robertson, Shirey-Rice, Jana K, Lipworth, Loren, Cronin, Robert M, Pulley, Jill, Kripalani, Sunil, Barkin, Shari, Johnson, Kevin B, Denny, Joshua C
Published in Journal of the American Medical Informatics Association : JAMIA (01.01.2018)
Published in Journal of the American Medical Informatics Association : JAMIA (01.01.2018)
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Journal Article
Interactive network-based clustering and investigation of multimorbidity association matrices with associationSubgraphs
Strayer, Nick, Zhang, Siwei, Yao, Lydia, Vessels, Tess, Bejan, Cosmin A, Hsi, Ryan S, Shirey-Rice, Jana K, Balko, Justin M, Johnson, Douglas B, Phillips, Elizabeth J, Bick, Alex, Edwards, Todd L, Velez Edwards, Digna R, Pulley, Jill M, Wells, Quinn S, Savona, Michael R, Cox, Nancy J, Roden, Dan M, Ruderfer, Douglas M, Xu, Yaomin
Published in Bioinformatics (Oxford, England) (01.01.2023)
Published in Bioinformatics (Oxford, England) (01.01.2023)
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Journal Article
Leveraging Human Genetics to Identify Safety Signals Prior to Drug Marketing Approval and Clinical Use
Jerome, Rebecca N., Joly, Meghan Morrison, Kennedy, Nan, Shirey-Rice, Jana K., Roden, Dan M., Bernard, Gordon R., Holroyd, Kenneth J., Denny, Joshua C., Pulley, Jill M.
Published in Drug safety (01.06.2020)
Published in Drug safety (01.06.2020)
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Journal Article
A Phenome-Wide Association Study Uncovers a Pathological Role of Coagulation Factor X during Acinetobacter baumannii Infection
Choby, Jacob E, Monteith, Andrew J, Himmel, Lauren E, Margaritis, Paris, Shirey-Rice, Jana K, Pruijssers, Andrea, Jerome, Rebecca N, Pulley, Jill, Skaar, Eric P
Published in Infection and immunity (01.05.2019)
Published in Infection and immunity (01.05.2019)
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Journal Article
The Astounding Breadth of Health Disparity: Phenome-Wide Effects of Race on Disease Risk
Pulley, Jill M., Jerome, Rebecca N., Bernard, Gordon R., Shirey-Rice, Jana K., Xu, Yaomin, Wilkins, Consuelo H.
Published in Journal of the National Medical Association (01.04.2021)
Published in Journal of the National Medical Association (01.04.2021)
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Journal Article
Using Human ‘Experiments of Nature’ to Predict Drug Safety Issues: An Example with PCSK9 Inhibitors
Jerome, Rebecca N., Pulley, Jill M., Roden, Dan M., Shirey-Rice, Jana K., Bastarache, Lisa A., R. Bernard, Gordon, B. Ekstrom, Leeland, Lancaster, William J., Denny, Joshua C.
Published in Drug safety (01.03.2018)
Published in Drug safety (01.03.2018)
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Journal Article
Systematically Prioritizing Candidates in Genome-Based Drug Repurposing
Challa, Anup P, Lavieri, Robert R, Lewis, Judith T, Zaleski, Nicole M, Shirey-Rice, Jana K, Harris, Paul A, Aronoff, David M, Pulley, Jill M
Published in Assay and drug development technologies (01.12.2019)
Published in Assay and drug development technologies (01.12.2019)
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Journal Article
Repurposing N-acetylcysteine for management of non-acetaminophen induced acute liver failure: an evidence scan from a global health perspective
Jerome, Rebecca N, Zahn, Laura A, Abner, Jessica J, Joly, Meghan M, Shirey-Rice, Jana K, Wallis, Robert S, Bernard, Gordon R, Pulley, Jill M
Published in Translational gastroenterology and hepatology (2024)
Published in Translational gastroenterology and hepatology (2024)
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Journal Article
Reply to Ward and Colleagues’ Comment on “Using Human Experiments of Nature to Predict Drug Safety Issues: An Example with PCSK9 Inhibitors”
Jerome, Rebecca N., Pulley, Jill M., Roden, Dan M., Shirey-Rice, Jana K., Bastarache, Lisa A., Bernard, Gordon, Ekstrom, Leeland, Lancaster, William J., Denny, Joshua C.
Published in Drug safety (01.11.2018)
Published in Drug safety (01.11.2018)
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Journal Article
Accelerating Precision Drug Development and Drug Repurposing by Leveraging Human Genetics
Pulley, Jill M, Shirey-Rice, Jana K, Lavieri, Robert R, Jerome, Rebecca N, Zaleski, Nicole M, Aronoff, David M, Bastarache, Lisa, Niu, Xinnan, Holroyd, Kenneth J, Roden, Dan M, Skaar, Eric P, Niswender, Colleen M, Marnett, Lawrence J, Lindsley, Craig W, Ekstrom, Leeland B, Bentley, Alan R, Bernard, Gordon R, Hong, Charles C, Denny, Joshua C
Published in Assay and drug development technologies (01.04.2017)
Published in Assay and drug development technologies (01.04.2017)
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Journal Article
Advocating for mutually beneficial access to shelved compounds
Pulley, Jill M, Jerome, Rebecca N, Shirey-Rice, Jana K, Zaleski, Nicole M, Naylor, Helen M, Pruijssers, Andrea J, Jackson, James C, Bernard, Gordon R, Holroyd, Kenneth J
Published in Future medicinal chemistry (01.06.2018)
Published in Future medicinal chemistry (01.06.2018)
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Journal Article
Motivation for Launching a Cancer Metastasis Inhibition (CMI) Program
Pulley, Jill M., Jerome, Rebecca N., Ogletree, Martin L., Bernard, Gordon R., Lavieri, Robert R., Zaleski, Nicole M., Hong, Charles C., Shirey-Rice, Jana K., Arteaga, Carlos L., Mayer, Ingrid A., Holroyd, Kenneth J., Cook, Rebecca S.
Published in Targeted oncology (01.02.2018)
Published in Targeted oncology (01.02.2018)
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Journal Article
When Enough Is Enough: Decision Criteria for Moving a Known Drug into Clinical Testing for a New Indication in the Absence of Preclinical Efficacy Data
Pulley, Jill M, Jerome, Rebecca N, Zaleski, Nicole M, Shirey-Rice, Jana K, Pruijssers, Andrea J, Lavieri, Robert R, Chettiar, Somsundaram N, Naylor, Helen M, Aronoff, David M, Edwards, David A, Niswender, Colleen M, Dugan, Laura L, Crofford, Leslie J, Bernard, Gordon R, Holroyd, Kenneth J
Published in Assay and drug development technologies (01.12.2017)
Published in Assay and drug development technologies (01.12.2017)
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Journal Article
METHODS OF TREATMENT FOR GASTROINTESTINAL MOTILITY DISORDERS
Jerome, Rebecca N, Beaulieu, Dawn B, Pulley, Jill M, Shirey-Rice, Jana K, Zaleski, Nicole M
Year of Publication 17.08.2023
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Year of Publication 17.08.2023
Patent
METHODS OF TREATMENT FOR A KIDNEY DISEASE
Jerome, Rebecca N, Pulley, Jill M, Shirey-Rice, Jana K, Billings, IV, Frederic T, Zaleski, Nicole M
Year of Publication 05.10.2023
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Year of Publication 05.10.2023
Patent
METHODS OF TREATMENT FOR GASTROINTESTINAL MOTILITY DISORDERS
SHIREY-RICE, Jana K, ZALESKI, Nicole, BEAULIEU, Dawn B, PULLEY, Jill M, JEROME, Rebecca N
Year of Publication 16.12.2021
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Year of Publication 16.12.2021
Patent